Males In Age Group Research Articles

Morphometric Analysis of Great Cardiac Vein and its Clinical Implication-A Cadaveric Study

Introduction: Great Cardiac Vein (GCV) is the longest venous vessel of heart. It is the main tributary of the coronary sinus and anterior wall of the left ventricle and interventricular septum are drained by GCV. Aim: To study the morphometry of GCV and its variations in north-western region of India. Materials and Methods: The present cross-sectional study was conducted in the Department of Anatomy, SRMS IMS, Bareilly, Uttar Pradesh, India, from January 2012 to December 2013. Thirty hearts of different ages and of both sexes (22 males and 8 females) procured from cadavers in the department. The length and diameter of GCV were measured with help of thread and digital vernier calipers. The mean, standard deviation and correlation were calculated using Microsoft office excel 2007. Results: In present study, 30 hearts (mean age: 41.83±12.37 years) of both sexes (22 males and 8 females) were studied. The mean length of GCV was 79.26±22.78 mm and the range of length was from 55.50±27.57 to 112.33±36.07 mm. The mean diameter of GCV was 2.85±1.32 mm. The mean length of GCV in males was 83.26±22.05 mm, while in females, the mean length of GCV was 74.72±22.08 mm. The diameter of GCV was having significant relation with weight (r=-0.663, p-value=0.0007) and age group (r-0.481; p-value=-0.023) in cadaveric males. Conclusion: The present morphometric study of GCV provides data for measurement of interventional devices required during interventional procedure in Indian setting.

A study on prevalence of HIV and its associated risk factors in patients visiting tertiary care center of North India

Background: India is home to the second largest population of people living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) with an estimated 5.134 million infections. HIV has infected >75 million people worldwide, with an estimated 37 million people now living with the virus making it the major cause of morbidity and mortality worldwide. HIV is a significant public health problem with tremendous social and economic implications. Aims and Objectives: Our primary aim is to estimate the prevalence of HIV infection and the associated risk factors of HIV infection. Materials and Methods: This is a retrospective study of the patients who visited in integrated counseling and testing center (ICTC) and State Reference Laboratory at a tertiary care center of Agra, Uttar Pradesh from January 2017 to December 2021. The data are in accordance with NACO portal. Results: The highest HIV seropositivity was observed in 35–49 years age group in both males and females in three consecutive years 2017, 2018, and 2019, respectively. HIV seropositivity in males decreased from 8.3% in 2017 to 4.9% in 2021 and in females from 6.0% to 4.6%. The most seropositives belong to married population (41.2%) and the least in divorced population (4.2%). Overall, housewives (20.7%) were maximally affected by HIV seropositivity, followed by skilled workers (15.8%) and unemployed/retired persons (15.7%). Uneducated population had maximum seropositivity rate (35.3%). Majority of HIV positives were heterosexual non-commercial partner (47.4%), while the homosexuals were the least (1.8%) affected. Conclusion: This study highlights the most affected group of HIV seropositive population and their risk behavior. Thus, by making ICTC, more accessible to ramp up the focused screening and prevention efforts for the suspected HIV population and evolving the appropriate policies/strategies for public awareness program will help to reduce the spread of HIV infection among the masses.

INCIDENTES DE SEGURANÇA DO PACIENTE PEDIÁTRICO ANTES E DURANTE A COVID-19: ESTUDO DE MÉTODOS MISTOS

ABSTRACT Objective: to analyze the profile of pediatric patient safety incidents in a university hospital, with a particular focus on comparing notifications before and during the COVID-19 pandemic and on Nursing professionals' perception. Method: a mixed-methods and convergent strategy study conducted at a university hospital from southern Brazil. The data were collected from a database with 1,663 notifications between March and September 2021. After applying the inclusion criteria, a total of 418 records of patient safety incidents occurred between January 2019 and December 2020 were found, which were analyzed by descriptive statistics with SPSS 18.0; semi-structured interviews were carried out with 18 Nursing professionals, using thematic content analysis. Results: the safety incidents recorded in the pediatric units were more related to intravenous medications and fluids, male gender and infant age group. There were no relevant differences when comparing the notifications from 2019 (219) with those from 2020 (199), with a reduction of only 20 (-9.13%). In the professionals' perception, there was also no expressive change in this situation. Conclusions: the characteristics of the patient safety incidents that occurred in pediatric units showed few statistically significant differences in the periods investigated, corroborating the Nursing professionals' perception that there was no significant change in the institution's scenario regarding incidents. Strategies to encourage notifications and improvements in this system are still required to provide a safe environment to pediatric patients.

Assessment and comparison of cardiovascular disease risk factors and biochemical parameters among men and women: A cross-sectional study.

Background: Cardiovascular disease (CVD) is one of the most common causes of death among men and women worldwide. It is predicted that by 2030 around 23.3 million people will die as a consequence of CVD. There are numerous risk factors of CVD. The goal of this study is to examine the cardiovascular clinical and biochemical parameters of hospitalized CVD patients, as well as to assess the most common risk factors. Methods: 72 known healthy individuals were randomly allocated to the control group (male 47 and female 25). We collected data through a questionnaire from 154 CVD patients as a study group (male 108 and female 46). Cardiovascular status was assessed using clinical parameters like hypertension, chest pain, shortness of breathing, pain in the arm, and biochemical parameters like lipid profile, RBS, Creatinine, and an electrolyte panel. Inter- and intra-group comparison was performed using SPSS and Microsoft excel. Results: A total of 154 hospitalized CVD patients were analyzed (male 108 female 46) The most significant age group for males was observed 56- 65 years (mean 60) and female was 38-48 (43) years. A highly statistically significant increase was observed in total cholesterol and LDL in males than females, but a decrease in TG than females. Changes were also observed in other cardiovascular biochemical and clinical Parameters. Conclusion: There was a significant difference in smoking status, physical activity, lipid panel, and other biochemical parameters among males and females.

Behaviour, services and their future estimation towards nCOVID-19 patients in different waves of health care workers

Background: Health care workers (HCWs) presented frequent concerns regarding their health and their families health and high levels of psychological distress during nCOVID19 pandemic, we aimed to estimate towards the future services nCOVID-19 waves like 4th wave in India and their behavior, and services towards the nCOVID-19 Patients and whether HCWs are in more depression or anxiety level.Methods: We developed a questionnaire to study the HCWs. The questionnaire demography and data anxiety, depression behavior consists of 30 questions.Results: high-risk health care workers had elevated stress levels. We sent 200 questionnaires completed questionnaires were returned by 128 (64%) of the participants. Out of which 72 (36%) are incomplete or non-response data. Maximum age is from 30-35 male and 25-30, female age group. Highest number of male age groups from 30 to 35, 25 (37.31%), in case of female age groups from 25-30, 19 (31.15%). Overall, the number of Male 67 (52.34%) and female 61 (47.65%) of the study. From the above descriptive statistics gives that overall average age of female with standard deviation (29.98±6.38), and with overall male, average and standard deviation (32.27±6.60). Median age of female is 27 and Male is 30 years of age. By using the linear regression analysis, we predict the future behaviors and services for upcoming pandemic is very less anxiety and depression with (p<0.001) significant.Conclusions: In conclusion, our study highlights that HCWs are both female and male are predicted less depression and anxiety about the behavior and future pandemic services.

Hepatitis B DNA quantification in the serum of hepatitis B surface antigen-positive patients in Benghazi

Background: Hepatitis B virus (HBV) infection is a global public health problem, with about 240 million people affected worldwide. Serologic techniques are typically used to diagnose it. However, the decision as to which patient to treat or not remains challenging due to the poor sensitivity of serologic markers as prognostic or severity markers. Viral load (VL) determination using polymerase chain reaction techniques is a useful tool in decision-making.
 Aim: The aim of this study was to determine the pattern of HBV viral load levels in people of different age and sex groups, to predict the risk of hepatocellular carcinoma and liver cirrhosis in HBsAg positive patients in the east of Libya.
 Materials and Methods: This is a retrospective and descriptive study. Only one HBV VL test carried out on patients attending the Benghazi university center (from east of Libya) for specialized medical services prior to any HBV targeted therapy were included in the study over a period of 40 months (January 2014 to April 2018) . Hepatitis B DNA VL determinations were analyzed using Microsoft Excel 2010 and Minitab version 17.
 Results: A total of 431 patients, of whom 51.3% (210) were males and 48.7% (221) were females, were included in the study. Of the 431 patients, 31.3% (135) were below 30 years old, while 68.7% (296) were 30 years old or above. Around 31.1% (134) had measurable assay levels (20 - 2000 (Taq) IU/mL); 21.8% (94) had below 20 IU/mL; and 13.2% (57) had above 2000 IU/ml approximately 21.1% (91) had no detectable HBV DNA in their samples. 12.8% (55) of the patients had levels greater than 20000 IU/mL. The distribution of HBsAg positivity among the patients shows an increasing trend from the lower age group 0-10 to 21-30 in males and from 31-40 in females, then a decreasing trend from 31-40 to 81-90 age group in males and from 41-50 to 81-90 age group in females. A total of 431 patients were investigated for hepatitis B viral load, of whom 90.2% were HBeAg negative and 9.8% were HBeAg positive.

Analysis of Working Posture using Kinovea Software to Identify the Incidence of Forward Head among Bank Employees: A Cross-sectional Study

Background: Navi Mumbai is the most developed city in India and hence home for many banks. Purpose: The analysis was done to identify the Craniovertebral angle and their effects. Method: Hundred bankers who had spent at least one-year on the job participated in this survey. They were recruited by non-probability sample of convenience from various banks situated in Navi Mumbai. Results: Craniovertebral angle of 100 bank employees was measured. Forward head posture is identified by measuring Craniovertebral angle. Measurement of Craniovertebral angle is from C7 spinous process to tragus of ear. Majority of the employees observed as having forward head posture. Forward head posture is common in all age groups, mean age group in males is 22-44 years and normal Craniovertebral angle in them is about 48.8°. Mean age group in females is 23-55 years and normal Craniovertebral angle in them is about 47.6°. Normal Craniovertebral angle is 49.9°.

Identification of COVID-19 patients through voice for male age group using autocorrelation technique

Identification of COVID-19 patients through voice for male age group using autocorrelation technique

Improvements in survival for patients with stage IV adenocarcinoma in the lung, diagnosed between 2010 - 2020 - A population-based registry study from Norway.

We investigated how the prognosis for Norwegian patients with stage IV, adenocarcinoma (NSCLC) has developed during the last decade, to observe if increased survival coincides with the introduction of immunotherapy at a population level. Incidence data from the Cancer Registry of Norway are virtually complete and includes information about histological subtypes and biomarkers. The data was used to analyze median and relative survival for females and males diagnosed with stage IV NSCLC, divided by histological subgroups and age-groups. During 2010 - 2020, 14472 patients were diagnosed with lung cancer in stage IV, in Norway. Among them 6351 patients (43%) were classified with adenocarcinoma. The median survival has increased for both sexes, but the largest increase is seen in females. From 2010 to 2020, median survival for females in the 0-69 group increased from 6.7 months to 12 months and from 3.7 months to 10 months for the 70+ age group. For the equivalent male age groups, we see an increase from 6.1 months to 7.7 months for the 0-69 group, and an increase from 3.8 months to 4.5 months for the 70+ group. When excluding patients with EGFR/ALK mutations from the survival analysis, the groups continue to display an increased survival from 2010 to 2020, although modest in the male 70+ group. The 1-year relative survival (RS) has increased for both sexes, from 32.4% to 51.2 in females and 25.4% to 44.5% in males. When EGFR/ALK positive patients were excluded from the analysis 1-year RS in females rose from 32.4% to 47.4% and for males from 25.4% to 41.8%. A real-world patient population of stage IV, NSCLC adenocarcinoma have had a clinically meaningful increase in both median and relative survival from 2010 - 2020. The steepest survival increase has taken place after 2016, the time point where immunotherapy was implemented as a treatment option for the stage IV, adenocarcinoma population not harboring targetable mutations (EGFR/ALK).

Disease burden measured by patient-reported outcomes: does psoriatic arthritis feel worse than rheumatoid arthritis? A cross-sectional nationwide study.

To study the subjective disease burden of patients with psoriatic arthritis (PsA) and rheumatoid arthritis (RA), using patient-reported outcomes (PROs) cross-sectionally. Data of 3598 patients with PsA and 13913 with RA were extracted from the database. Measures included the VAS-values of pain, fatigue and patient global assessment (PGA), HAQ, and disease activity at the most recent visit/remote contact in the period 1.2020 to 9.2021. Values were compared between patients with PsA and RA overall, and by sex and age (<50, 50-59, 60-69 and ≥70 years). Regression analyses were applied. The overall median (IQR)-values for pain were 29 (10, 56) for PsA and 26 (10, 51) for RA, 29 (9, 60) and 28 (8, 54) for fatigue, 28 (10, 52) and 29 (11, 51) for PGA, 0.4 (0, 0.9) and 0.5 (0, 1.0) for HAQ (p<0.001 for all comparisons; adjusted for sex and age). The median (IQR)-values for pain, fatigue, PGA and HAQ were higher for PsA vs. RA in most age groups for males and females. All PROs were higher in older patients with both diagnoses. The median values for DAS28, doctor global assessment, ESR and CRP were 1.9 vs. 2.0, 8 vs. 8, 7 vs. 8 and 2 vs. 3 in PsA and RA, respectively. Overall, both PsA and RA groups showed moderate disease control by patients' perspective, but the burden of disease was higher especially in women with PsA compared to RA. Disease activity was similar and low in both diseases.

Dry eye among computer operators at a tertiary care centre in India.

There is global digitalization. With the increased use of computers in the workplace, refraction and dry eye related health concerns are developing. This study is conducted to evaluate the effects of long-term computer use on tear production and evaporation. Thisis a cross-sectional study among 97 computer operators in a Tertiary care centre. Dry eye disease was assessed subjectively with the Ocular Surface Disease Index (OSDI) questionnaire and objectively by performing Schirmer's test and Tear Break-up Time (TBUT). Majority of participants (59.2%) were male's age group between 36- 40 years. The prevalence of dry eye among the computer Operators was found to be 51%. Mean TBUT and mean Schirmer's Test value for those with dry eye was 12.65s and 10.3mm respectively. This study showed that a positive relation between dry eye and computer usage. Computer users are predisposed to developing dry eye diseases. It is therefore necessary for them to go for regular ophthalmic examination to prevent dry eye symptoms and disease.

Time Trend of Upper Gastrointestinal Cancer Incidence in China from 1990 to 2019 and Analysis Using an Age-Period-Cohort Model.

The aim of this study was to investigate the upper gastrointestinal cancer incidence trend in China from 1990 to 2019 with Joinpoint software and to evaluate the age effect, cohort effect, and period effect using the age–period–cohort model, with the data obtained from the Global Burden of Disease, Injuries, and Risk Factors Study. The crude incidence rate (CR) of upper gastrointestinal cancer in China increased from 41.48/100,000 in 1990 to 62.64/100,000 in 2019, and the average annual percent change (AAPC) was 1.42 (p < 0.05). The age-standardized incidence rate (ASIR) decreased from 50.77/100,000 to 37.42/100,000, and the AAPC was −1.12 (p < 0.05). The net drift was −0.83 (p < 0.05), and the local drifts in the 35–79 age groups of males and all age groups of females were less than 0 (p < 0.05). The age effect showed that the upper gastrointestinal cancer onset risk gradually increased with age, the period effect was fundamentally manifested as a downward trend in onset risk after 2000, and the cohort effect indicated the decreased onset risk of the overall birth cohort after 1926. The ASIR of upper gastrointestinal cancer in China from 1990 to 2019 showed a downward trend, and the onset risk indicated the age, period, and cohort effects.

Türk Çocuklarında Kemik Yaşı Tespitinde “GÖK Atlas” ile “Gilsanz-Ratib Atlas“ın Güvenilirliğinin Karşılaştırılması

Aim: In this study we aimed to evaluate which of the GÖK and GR atlases is more compatible with chronological age in Turkish children aged 5-10 years.&#x0D; Material and Method: In this study, the wrist radiographs of patients aged 5-10 years who applied to İzmir Bakırçay University Çiğli Training and Research Hospital due to trauma were retrospectively analyzed. A total of 360 wrist radiographs were evaluated. Bone age estimates in both groups were compared with chronological ages. &#x0D; Results: In the correlation analysis, the prediction rate with 1-difference tolerance is 88.9% in the GR atlas and 76.7% in the GÖK atlas, while both atlases predict 99% correctly with two-difference tolerance. GR Atlas 168 (46.2%) and GÖK Atlas 147 (40.8%) predicted correctly regardless of gender and age. Of the correct estimations, 53.5% in the GR atlas and 57.8% in the GÖK atlas were male cases. İn male age group at the age of 6 and 10, the GR atlas is more successful, at the age of 7, the GÖK Atlas is more successful, and at the age of 5, 8, and 9 the success of both atlases is the same. İn female age group at the age of 5,7, 8, and 10 the GR atlas is more successful, at the age of 6 and 9 the GÖK Atlas is more successful&#x0D; Conclusion: The GR Atlas was more accurate than the GÖK Atlas. Both the GR Atlas and the GÖK Atlas predicted more accurately in males. Since reference values for bone age can change with environmental and genetic factors all over the world, it is beneficial for all races to create atlas models with multicenter studies in order to establish their own standards.

Male partner age, viral load, and HIV infection in adolescent girls and young women: evidence from eight sub-Saharan African countries.

We aimed to elucidate the role of partnerships with older men in the HIV epidemic among adolescent girls and young women (AGYW) aged 15-24 years in sub-Saharan Africa. Analysis of Population-based HIV Impact Assessments in Eswatini, Lesotho, Malawi, Namibia, Tanzania, Uganda, Zambia, and Zimbabwe. We examined associations between reported partner age and recent HIV infection among AGYW, incorporating male population-level HIV characteristics by age-band. Recent HIV infection was defined using the LAg avidity assay algorithm. Viremia was defined as a viral load of more than 1000 copies/ml, regardless of serostatus. Logistic regression compared recent infection in AGYW with older male partners to those reporting younger partners. Dyadic analysis examined cohabitating male partner age, HIV status, and viremia to assess associations with AGYW infection. Among 17 813 AGYW, increasing partner age was associated with higher odds of recent infection, peaking for partners aged 35-44 (adjusted odds ratio = 8.94, 95% confidence interval: 2.63-30.37) compared with partners aged 15-24. Population-level viremia was highest in this male age-band. Dyadic analyses of 5432 partnerships confirmed the association between partner age-band and prevalent HIV infection (male spousal age 35-44-adjusted odds ratio = 3.82, 95% confidence interval: 2.17-6.75). Most new infections were in AGYW with partners aged 25-34, as most AGYW had partners in this age-band. These results provide evidence that men aged 25-34 drive most AGYW infections, but partners over 9 years older than AGYW in the 35-44 age-band confer greater risk. Population-level infectiousness and male age group should be incorporated into identifying high-risk typologies in AGYW.

Evaluation of biochemical markers for detection of chronic kidney diseases (CKD) in covid positive patient among hospitalize individuals

In evaluating diagnosis of CKD can detect in covid-19 positive patient by estimation of few bio-chemical markers like erythropoietin level, cystatin-C (CysC), BTP (beta trace protein.), IL- 6, IL-8 and TNF alpha. Those chemical parameters usually may be potential diagnostic aspect. The study was undertaken to determine the prevalence of biochemical markers of CKD in covid positive patients those are taking dialysis twice in a week and also to evaluate the risk factors among 50 ICU and non-ICU individuals at salboni super speciality hospital, WB over a period of 6 months (June 2020 to Nov 2020). Blood samples were collected by using venipuncture technique from ICU and non-ICU individuals then serum is separated from the whole blood sample. Then the serum samples were performing CLIA immunoassay technique for detecting those biomarkers. Erythropoietin level was decreased significantly across CKD in age group (40-49) and also age group (50-59) for female and for the male age group (30-39) is significantly decreased in EPO level. Whereas the rest age groups are significantly increased in EPO level. Beta trace protein of all the groups are significantly increased remaining age group (40-49) for male. Cystatin C level, IL-6, IL-8, TNF alpha level is significantly increased of all the groups both male and female. This is in contrast to the bio-chemical markers of CKD in covid patient, many of which are new and unfamiliar to clinicians, relatively costly, and lack the demonstrated clinical benefit over current methods to fully justify their wide implementation.

Intracranial Magnetic Resonance Venography of Superior Sagittal Sinus, Straight Sinus and Cerebral Venous Channels: Normal Anatomy and Variations in North Indian Population

Abstract The intracranial dural venous sinuses can be injured leading to thrombosis with in the dural sinuses causing headache, abnormal vision, weakness of the face and limbs on one side of the body, and seizures.Magnetic Resonance Venography (MRV) is one of the preferred methods of evaluation of the cerebral venous sinus anatomy, variations and pathology, particularly in the diagnosis of venous sinus thrombosis. The purpose of this study is to evaluate the use of MRV to depict the normal intracranial venous anatomy and its variants in North Indian population which can help to avoid potential pitfalls in the diagnosis of dural venous sinus thrombosis, venous infarcts and venous hemorrhage. Aim:The purpose of this study is to evaluate the use of MRV to depict the normal intracranial venous anatomy and its variants in North Indian population, which can help to avoid potential pitfalls in the diagnosis of dural venous sinus thrombosis, venous infarcts and venous hemorrhage. Materials:The present study was undertaken in the Departments of Anatomy and Radiodiagnosis at a North Indian tertiary care teaching hospital over a period of two years. Magnetic Resonance Venograms (MRV) of patients attending the radiology department were used to study the normal anatomy and variations in the dural venous sinuses. 50 MRV scans of which 26 were of females and 24 of male, were included in the study. Anatomical variations and variations in drainage of the dural venous sinuses were assessed and statistical analysis was done. Results:For both superior sagittal sinus drainage and straight sinus drainage, the proportion of veins draining in right and left transverse sinuses and confluence of sinuses was significantly different in the two age groups (p&lt;0.001) in both males and females. Partial splitting of superior sagittal sinus in anterior one third or posterior one third was also seen. Statistically significant findings were observed regarding the laterality for vein of Labbe &amp; vein of Trolard. Conclusion:MR venography is an excellent diagnostic technique to visualise anatomy and anatomic variations of venous sinuses as observed in our study. The partial splitting of superior sagittal sinus in either anterior one third or posterior one third as seen in our study, can cause misdiagnosis of thrombosis. Hence, knowledge of normal anatomy and anatomic variations in the intracranial venous sinuses is very important to diagnose cerebral venous sinus thrombosis accurately.

Sex differences in suicide mortality in Newfoundland and Labrador: An observational study with medical examiner data from 1997 to 2016.

Globally, the suicide rate is two times higher for males than for females. Previous studies in Newfoundland and Labrador did not examine age-specific rates by sex. The objectives of this study were to determine suicide rates by sex and age group and to compare the demographic and clinical characteristics of males and females who died by suicide. This observational study analyzed a routinely collected dataset based on all medical examiner-determined suicide deaths among people aged 10 years and older in Newfoundland and Labrador, Canada, between 1997 and 2016. Age-standardized and age-specific suicide rates and rate ratios were calculated based on the number of deaths during the period, and descriptive statistics were used to compare demographic and clinical characteristics between males and females. The age-standardized suicide rate was 4.6 times higher among males than females and was higher for males in most age groups. Rates were highest in the young adult age groups for males (20 to 24 years) and females (35 to 39 years). Males who died by suicide were more likely to be from a rural community and to have died by firearm; females were more likely to die by self-poisoning and to have had a mental illness or substance use history. The results are broadly consistent with previous research, though this is the first study to report age-specific suicide rates among females across the life course in Newfoundland and Labrador. The results underscore the need to design public health and clinical interventions that account for sex differences in suicide risks.

Trends in incidence and mortality of esophageal cancer in China 1990-2019: A joinpoint and age-period-cohort analysis.

BackgroundThe incidence and mortality trends of esophageal cancer (EC) remain unknown in China. This study aimed to describe the trend in incidence and mortality of EC in China.MethodsWe extracted age-standardized rates and numbers of EC in China for 1990−2019 from the Global Burden of Disease study 2019. The age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) were calculated to describe the trends, while the annual percentage of change and the average annual percent change (AAPC) were analyzed by the joinpoint regression analysis. The incidence and mortality data were analyzed via age-period-cohort model analysis.ResultsThe ASIR and ASMR decreased slightly before 1999, then increased from 1999 to 2004, and decreased again thereafter, with overall AAPC values of −2.5 (−2.8, −2.1) for females and -0.9 (−1.1, −0.8) for males regarding incidence, with overall AAPC values of −3.1 (−3.3, −2.9) for females and −1.2 (−1.3, −1.1) for males regarding mortality. As a whole, the relative risk (RR) of EC increased with age in both females and males regarding incidence and mortality, except for the 80–84-year-old age group in females and the 85–89-year-old age group in males regarding incidence, where they began to decrease. The RR of EC increased with age in females and males regarding mortality, except for the 85–89-year-old age group in males. The time period showed a trend of first rising and then decreasing, and the RR of time period effect was lower in 2015 than that in 1990 in females regarding both incidence and mortality, whereas males showed a significant upward trend in both incidence and mortality. The birth cohort effect showed an overall downward trend.ConclusionsThe overall incidence and mortality of EC in China shows an increased and then decreased trend from 1990 to 2019. The AAPC decreased in incidence and mortality from 1990 to 2019. The RR of incidence and mortality of EC in China is greatly affected by age in both sexes, by time period in male, we should be paid more attention to.

No Postoperative Change in Body Mass Index Was Observed Among Adolescent Female Patients After Sports or Trauma Surgery

Purpose: The purpose of this study was to identify whether adolescent females are more prone to postoperative BMI decreases when compared to other female age groups and all male age groups. We hypothesized postoperative BMI would decrease in adolescent females when compared to males and younger females. Methods: A list of patients aged 5 to 19 who underwent surgery from 2016-2020 was generated with the 50 most frequently used diagnosis codes of two orthopedic surgeons at an orthopaedic hospital. Patients were excluded if they had undergone multiple surgeries. BMI data was collected at baseline and 2-8 months post-surgery. Patients were divided in cohorts by age: school-age, pre-adolescent, and adolescent. Results: A total of 156 patients were analyzed with a mean BMI of 20.9. There were 24 school-aged, 72 pre-adolescent, and 60 adolescent patients. No statistically significant difference in BMI change was noted between groups as determined by one-way ANOVA (p=0.86). Conclusion: There were no significant postoperative changes in BMI between males and females over the time intervals measured, however, surgeons should still be attentive to this risk. Further research focused on subtle changes in eating habits is necessary to determine if eating disorders develop without BMI changes following surgical intervention.

COVID-19 vaccination and myocarditis: A review of current literature.

Vaccination for coronavirus disease 2019 (COVID-19) is a critical strategy in controlling the current pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). After widespread COVID-19 vaccine imple-mentation, isolated case reports about myocarditis as a potential adverse reaction started coming. As of November 12, 2021, Centers for Disease Control and Prevention (CDC) has reported 1793 cases of myocarditis or pericarditis among young people with age 12-29 years, most cases have been reported in the male adolescent age group after the second dose of mRNA COVID-19 vaccines. It is very important to monitor the safety standards and adverse reactions of vaccines to effectively implement the vaccination policies. The CDC and the United States Food and Drug Administration actively monitor vaccine-associated adverse reactions a well-known platform such as Vaccine Adverse Event Reporting System. CDC continues to recommend COVID-19 vaccines and booster doses for eligible individuals (age limit according to the type of vaccine) after careful consideration from risk-benefit assessment and favorable outcomes from vaccination. Mechanisms behind COVID-19 vaccine-induced myocarditis are not clear yet but several possibilities such as molecular mimicry between the spike protein of SARS-CoV-2 and self-antigens, immune response to mRNA, and activation of host immunological system, trigger of the pre-existing dysregulated immunological system have been documented in the literature. Overall, data suggests a good prognosis, especially in young patients. In this review article, we cover currently available data on COVID-19 vaccine-related myocarditis incidence, concerns, possible mechanisms of myocarditis, current treatment, and outcome trends, risk vs benefit assessment of COVID-19 vaccination in this current pandemic.