On 8 January 2022, an earthquake with Ms 6.9 struck Menyuan County, Qinghai Province, China, which provides an opportunity to investigate the seismotectonics of the Qilian-Haiyuan fault in northeast Tibet. We collect seismic observation data from China Seismic Network Center from 8 January to 6 February 2022 around the 2022 Menyuan mainshock. The double-difference relocation algorithm is applied to relocate 904 earthquakes, and 820 high-precision hypocenter locations are obtained. The mainshock epicenter was located at 10.2 km depth in the Tuolaishan fault. The aftershock sequence extended towards nearly E-W along the Tuolaishan fault and NW-SE along the Lenglongling fault, parts of the Qilian-Haiyuan fault, but there were fewer aftershocks at the beginning of the rupture near the intersection between the Lenglongling and Tuolaishan faults, suggesting a conjugated type of rupturing with a seismic gap. Integrating with focal mechanism solutions of mainshock and one large aftershock, we suggest that the rupture is a left-lateral strike-slip event with a high dip. The stress change around the faults intersection. The 1986 Ms 6.4 earthquake may trigger the 2016 Ms 6.4 earthquake, and then the extrusion stress could transfer to around the 2022 Ms 6.9 earthquake source area due to the Indo-Eurasian collision. Previous tomographic models revealed low-velocity anomalies under the Menyuan earthquakes, reflecting that fluids could decrease friction coefficient and normal stress on the fault planes and further promote the generation of these earthquakes. These fluids could be contained in the lower crustal flow and mantle upwelling flow under northeast Tibet.