The two moderate earthquakes that occurred close and to the north of the North Aegean Trough (NAT) on 26 September 2020 (Mw5.3) and 16 January 2022 (Mw5.4), both followed by aftershock activity, are examined. Seismic activity along the NAT and its parallel branches is continuous and remarkable, with numerous strong instrumental (M≥6.0) earthquakes. Yet, the frequency of moderate (5.0≤M<6.0) earthquakes outside these major fault branches is rather rare and therefore their investigation provides the optimal means to decipher the seismotectonic properties of the broader area. The temporal and spatial proximity of the two seismic excitations from late September of 2020 through early 2022, intrigues for exhaustive investigation of seismic activity with the employment of earthquake relocation techniques, moment tensor solutions and statistical analysis. Our research revealed that this seismic activity purely falls inside the Mainshock – Aftershock type, with fast aftershock decay rates and moderate productivity. According to our findings, the two seismic sequences, despite their close proximity, exhibit distinctive features as a result of the intricate stress field generated at the western termination of the NAF system in an extensional domain.