In the domestic cat (FeZis catus) phenol is converted mainly to phenylsulphate with only small amounts of phenylglucuronide [l] . The cat’s ability to form the glucuronides of foreign compounds is low compared with other species [2] and it forms little or no glucuronide with phenol [I], benzoic acid [3], sulphadimethoxine [4] , or 1-naphthylacetic acid [5]. It was of interest therefore to find out whether catlike animals were similar to the domestic cat. The above four compounds were administered to weaned lion cubs (Panthera Zeo) and adult African civets (Viverra civet&) and forest genets (Genetru par&m) and their urine examined for metabolites. These animals showed little or no glucuronide formation with these compounds and they excreted phenol almost entirely as phenylsulphate, benzoic acid mainly as hippuric acid, 1-naphthylacetic acid as the glycine conjugate and sulphadimethoxine as such and as the N4-acetyl derivative. As far as conjugation is concerned, these compounds behave in the lion, civet and genet much as they do in the domestic cat.