Afar Region Research Articles

Retraction Note: Effect of Covid-19 on households welfare in Afar Regional State, Ethiopia

Retraction Note: Effect of Covid-19 on households welfare in Afar Regional State, Ethiopia

Low Measles Vaccination Coverage and Spatial Analysis of High Measles Vaccination Dropout in Ethiopia's Underprivileged Areas.

(1) Background: Measles remains a major cause of disease and death worldwide, especially in the World Health Organization African Region. This study aimed to estimate the coverage of measles vaccinations and map the spatial distribution of measles vaccination dropout in Ethiopia; (2) Methods: A cross-sectional survey was conducted in Ethiopia's underprivileged areas. The study included 3646 mothers/caregivers of children. ArcGIS for the spatial analysis, Global Moran's I statistic for spatial autocorrelation, and Getis-Ord Gi* statistics for hot spot analysis were applied; (3) Results: Overall, coverages of measles-containing-vaccine first- and second-doses were 67% and 35%, respectively. Developing regions had the lowest coverages of measles-containing-vaccine first- and second-doses, 46.4% and 21.2%, respectively. On average, the measles vaccination dropout estimate was 48.3%. Refugees had the highest measles vaccination dropout estimate (56.4%). The hot spot analysis detected the highest burden of measles vaccination dropout mainly in the northeastern parts of Ethiopia, such as the Afar Region's zones 1 and 5, the Amhara Region's North Gondar Zone, and peripheral areas in the Benishangul Gumuz Region's Assosa Zone; (4) Conclusions: The overall measles vaccination coverages were relatively low, and measles vaccination dropout estimates were high. Measles vaccination dropout hot spot areas were detected in the northeastern parts of Ethiopia.

Mapping the spatial disparities of HIV prevalence in Ethiopian zones using the generalized additive model

HIV is a worldwide social and health pandemic that poses a significant problem. This study contributes to the 2030 global agenda of reducing HIV prevalence. The study analyzed HIV prevalence using the 2016 Ethiopian Demographic and Health Survey data. The study included men aged 15–54 years and women aged 15–49 years who responded to questions about HIV tests. A generalized geo-additive model (GAM) was fitted to HIV data using nonparametric smooth terms for geolocations. Two smoothing techniques were used in GAMs to evaluate spatial disparities and the probable effects of variables on HIV risk. There were certain areas in Ethiopia that were identified as hot spot zones for HIV, including Nuer and Agnuak in Gambella, West Wollega and Illubabor in Oromia, Benchi Maji and Shaka in SNNPR, Awsi, Fantana, Kilbet, and Gabi in the Afar region, Shinilie of the Somalia region, North and South Wollo, Oromia special zones of the Amhara region, Central Ethiopia, and Addis Ababa city. On the other hand, the eastern parts of Ethiopia, particularly most zones in the Somalia region, were identified as cold spot zones with the lowest HIV odds ratio. The odds of HIV+ were higher for those who reside in rural areas than in urban areas. Furthermore, people who have STIs, who used contraceptive methods, and who learned at the secondary level of education were more likely to be infected with HIV. After adjusting for confounding variables, the results indicated that there are substantially significant spatial variations in HIV prevalence across Ethiopian zones. These results provide essential information to strategically target geographic areas to allocate resources and policy interventions at zonal level administrations.

Inequities and trends of polio immunisation among children aged 12–23 months in Ethiopia: a multilevel analysis of Ethiopian demographic and health survey

IntroductionDespite Ethiopia’s policy intention to provide recommended vaccination services to underprivileged populations, inequity in polio immunisation persists.ObjectiveThis study examined inequity and trends in polio immunisation and determinant factors among children...

Determinants of Overweight Among Type Two Diabetes Mellitus Patients Attending Public Hospitals At Awusi Resu Zone of Afar Region: Unmatched Case-Control Study.

Diabetes is a major cause of morbidity and mortality; affecting More than 415 million people. The primary aim of this study was to assess the determinants of being overweight among Type 2 Diabetic patients attending diabetic clinics of public Hospitals in the Awusi resu zone of Afar region, Northeast Ethiopia. A hospital-based unmatched case-control study design was conducted from May 5 to June 5/2021 by systematic random sampling 286 study participants were involved in the study (96 cases and 190 controls); Logistic regression analysis was performed to identify the best model of factors leading to overweight. The odds ratio and 95% confidence interval were used as a measure of association. Those who have attended college and above have an AOR; of 10.30 CI: (4.16-25.50) ten times higher odds of being overweight when compared to those unable/able to read. Only those who have a family history of diabetes AOR: 3.10 CI (1.04-9.30) have three folds of being overweight when compared to their counterparts. Of those who use insulin for controlling blood glucose (AOR: 0.14 CI (0.03-0.74) 96% at less likely to be overweight compared to those who use exercise. In this study, educational level, Family History, and type of blood glucose controlling mechanism were important predictors of overweight on T2DM. Moreover the diabetes patients were recommended to use insulin for controlling blood glucose.

Optimization and evaluation of alternative village-based breeding plans: the case of goats in Afar region, Ethiopia

The study aims to design and evaluate alternative village-based breeding plans for Afar goats in Aba’ala, Afar region, Ethiopia. The alternative breeding plans were designed and evaluated using ZPLAN+ computer program following the gene flow method and selection index procedures. Input parameters were sourced from a production system survey study, own-flock ranking exercises and literature. The breeding goal traits included six-month weight, daily milk yield and proportions of weaned kids. Four alternatives were designed based on the variation of the number of the traits in the selection index (recording) while keeping all traits in the aggregate breeding goal. Furthermore, the proposed alternative plans were evaluated by varying the years of breeding buck service period. Higher annual genetic gain was estimated for six-month weight (0.2983 kg) in alternative 4, for daily milk yield (0.0083 kg or 8.3 g) and proportion of lambs weaned (0.0142%) in alternative 1 when the years of buck use for breeding was set to two years. Higher selection accuracy was obtained in alternative 1 when all the traits were included in the selection index while lower selection accuracy was achieved in alternative 4 when six-month weight only was included in the selection index. The highest profit per doe per year was achieved in alternative 1 (1.221€) while the lowest was obtained in alternative 4 (0.885 €) when six-month weight only is included in the selection index. The simulation results gave an acceptable range of genetic gains with little difference across the alternatives. Therefore, village breeding programs with a few traits in the recording and two years of breeding buck use are deemed practicable. The proposed breeding plans should be part of the national development strategies and involvement of local research institutions and universities is very crucial to ensure adequate technical support.

Early newborn bathing practice and its determinants among postpartum women in Ethiopia: a systematic review and meta-analysis

BackgroundEarly baby bathing has a major negative impact on the newborn's health. Even though early newborn bathing has numerous detrimental effects on neonatal health, evidence has provided little attention on the current level of practice. Furthermore, there is a dearth of data regarding the overall effects of early newborn bathing in Ethiopia, which would be helpful to program and policy designers. This meta-analysis aimed to ascertain the level of early bathing practice and its determinants among postpartum women in Ethiopia.MethodsAll articles were searched from the Web of Sciences, CINAHL (EBOSCO), Science Direct, MEDLINE, PubMed, Google Scholar, and Google websites from inception to October 10, 2023. The meta-analysis was performed using Stata version 18. The summary estimates with 95% CI were estimated using the random effect model with the Der Simonian Liard method. Heterogeneity was explored using Galbraith plot, Cochrane Q statistics, I2 statistics, and test of theta. To deal with the observed heterogeneity, subgroup analysis, sensitivity analysis, and meta-regression were done.ResultsThis meta-analysis included a total of 2787 postpartum women. The pooled level of early newborn bathing practice among postpartum women in Ethiopia was 55% [95% CI: 38–71]. Based on subgroup analysis by region, the highest level of early newborn bathing practice was among studies conducted in the Afar region which was 73% (95% CI: 69–77). There is a significant association between maternal level of education and early newborn bathing practice among postpartum women in Ethiopia (AOR = 0.51, 95% CI: 0.24, 0.78).ConclusionsIn this meta-analysis, the overall estimate illustrates that more than half of postpartum women practice early newborn bathing in Ethiopia. Maternal level of education was significantly associated with early newborn bathing practice. Thus, both the government and all the concerned stakeholders should take coordinated action to boost information dissemination and awareness creation among postpartum women thereby reducing the practice of early newborn bathing and alleviating consequences of early newborn bathing.

Evaluate the current and predict the future real GDP of Afar regional state, Ethiopia

Ethiopia has implemented numerous national development plans and strategies to achieve sustainable economic growth at both the national and regional levels, specifically in the Afar region. However, there has been a lack of assessment regarding the outcomes and expected goals of these plans and strategies, particularly for the regional economy. Hence, this study assesses the current and future gross domestic product (GDP) of Ethiopia’s Afar regional state. It analyzes the data using a descriptive and econometric model called autoregressive integrated moving average (ARIMA). The analysis shows that the regional GDP has been increasing over time, but per capita income remains below the national average. The service sector dominates the economy, while the growth of the industry sector has been stagnant. This indicates that development policies have not achieved their goals of reducing poverty and transforming the economy. Using the ARIMA model, it is projected that the Afar regional GDP will gradually increase from 19,300.20 Billion Birr to 21,678.20 Billion Birr between 2023q1 and 2025q4, with an average growth rate of 10%. It is important for development policies to prioritize not just economic growth, but also social development within local communities. This involves addressing issues related to institutional capacity, and governance, and leveraging agricultural resources to benefit agro-pastoralists and pastoralists, as the agricultural sector is the main driver of the economy. By understanding the present and projected GDP of the Afar regional state, policymakers and stakeholders can make informed decisions for sustainable and inclusive economic growth.

Predicting the peak flow and assessing the hydrologic hazard of the Kessem Dam, Ethiopia using machine learning and risk management centre-reservoir frequency analysis software

Abstract Flooding due to overtopping during peak flow in embankment dams primarily causes dam failure. The Kessem River watershed of the Awash basin in the Rift Valley of the Afar region in Ethiopia was studied intricately to predict the causes of the Kessem Dam safety using machine learning predictive models and risk management centre-reservoir frequency analysis. Recently developed recurrent neural network predictive models with hybrid Soil Conservation Service Curve Number (SCS-CN) were used for simulation of river flow. Peak daily inflow to the reservoir is predicted to be 467.72, 435.88, and 513.55 m3/s in 2035, 2061, and 2090, respectively. The hydrologic hazard analysis results show 2,823.57 m3/s and 935.21 m; 2,126.3 m3/s and 934.18 m; and 11,491.1 m3/s and 942.11 m peak discharge and maximum reservoir water level during the periods of 2022–2050, 2051–2075, and 2076–2100, respectively, for 0.0001 annual exceedance probability. The Kessem Dam may potentially be overtopped by a flood with a return period of about 10,000 years during the period of 2076–2100. Quantitative hydrologic risk assessment of the dam is used for dam safety evaluation to decide whether the existing structure provides an adequate level of safety, and if not, what modifications are necessary to improve the dam's safety.

Pre-lacteal feeding practice and its associated factors among mothers with children under the age of two years in Dubti town, Afar region, North East Ethiopia: a community based mixed study design.

Pre-lacteal feeding prevents the early initiation of breastfeeding and exclusive breastfeeding. It is understudied in Afar, a pastoral region in northeast Ethiopia. The study assessed the prevalence of pre-lacteal feeding practice and its associated factors among mothers with children under the age of two years in Dubti, North East Ethiopia. A community-based mixed-study design was employed. A systematic sampling technique was used to recruit 370 study participants for the quantitative study, while purposive sampling was used to select 17 study participants for the qualitative study. Logistic regression analysis was used to determine the association between independent variables and dependent variable. The results of logistic regression analysis were presented as an odd ratio with a 95% CI. A P-value <0.05 was used as a cutoff point to determine statistical significance. The qualitative data were analyzed using a thematic approach. Pre-lacteal feeding was practiced by 36% of mothers. Afar ethnicity (AOR = 2.5, 95% CI: 1.2-5.1), an extended family size (≥5) (AOR = 1.73, 95% CI: 1.02-2.9), a birth interval of less than 2 years (AOR = 2.77, 95% CI: 1.59-4.82), the first birth order of an indexed child (AOR = 3.87, 95% CI: 2.14-7.0), male-indexed children (AOR = 2.95, 95% CI: 1.67-5.2), and no antenatal care visits (AOR = 2.67, 95% CI: 1.67), or once or twice antenatal visits were significantly associated with pre-lacteal feeding practice. Breastfeeding counseling (AOR = 0.38, 95% CI: 0.2-0.7) and delivery at a health institution (AOR = 0.3, 95% CI: 0.17-0.55) were protective factors of pre-lacteal feeding practice. The most common pre-lacteal foods were dairy products, water, and certain plant species. Cultural beliefs are the main reason for practicing these pre-lacteal feedings. A significant number of study participants practiced prelacteal feeding. A public health campaign emphasizing the importance of antenatal care follow-ups should be initiated. Breastfeeding counseling and delivery in a health facility should also be strengthened. Community health education about the disadvantages of pre-lacteal feeding practices should be provided to reduce traditional beliefs.

Biting Flies and Associated Pathogens in Camels in Amibara District of Afar Region, Ethiopia.

Biting flies and associated pathogens are the major health constraints on camel production and productivity and are implicated in causing significant economic losses in the pastoralist community in Ethiopia. A cross-sectional study was conducted to estimate the prevalence of biting flies and their associated pathogens in relation to different risk factors in camels in the Amibara district, from October 2019 to April 2020. A total of 480 camels were examined for biting flies and associated pathogens. The study revealed that overall, 87% (418/480) and 18% (87/480) of camels were infested by one or more biting flies and infected with Trypanosoma evansi during the study period, respectively. The collected biting flies were identified into a total of 3 genera: Hippobosca, Stomoxys, and Tabanus under the stereomicroscope. In the present study, Hippobosca (40.4%) was the most prevalent biting fly, followed by Stomoxys (31%) and Tabanus (28.6%), which affected camels in the study area. Among camels infected with Trypanosoma evansi, 7.3% and 16% were positive for parasitological and serological tests, respectively. Age, body condition score, and season appeared to have a significant effect (p ≤ 0.005) on the prevalence of biting flies and T. evansi on dromedaries. According to the findings of this study, biting flies and Trypanosoma evansi were the most common limitations on camel health, production, and productivity in the study area. As a result of the possible threat of biting flies' infestation and Trypanosoma evansi on camels, all-around attention is required in terms of strategic acaricide application, proper antiprotozoal drug use, and raising knowledge about acaricide use to prevent and control biting flies' infestation.

High seroprevalence of IgM antibodies against chikungunya among patients with acute febrile illness seeking healthcare in a malaria-endemic area in the Afar Region, Northeast Ethiopia.

Chikungunya is a disease caused by Aedes mosquito-borne chikungunya virus infection. This disease is becoming one of the emerging/re-emerging viral diseases in tropical and subtropical countries but is neglected by public health systems. This study assessed the seroprevalence of chikungunya virus infection among patients with acute febrile illness seeking healthcare in a malaria-endemic area in the Afar Region, Northeast Ethiopia. An institution-based cross-sectional study was employed from September 2022 to March 2023 to assess the seroprevalence of chikungunya virus infection among malaria-suspected febrile patients attending health institutes in the Afar Region. Sociodemographic, clinical features, and venous blood were collected from each study participant. Blood films were prepared and examined for plasmodium infection using microscopy. Sera were separated and screened for anti-chikungunya virus IgM and IgG antibodies using an enzyme-linked immunosorbent assay. Data were entered into Epi Data 3.1 and analyzed using Stata/SE 14.2. In this study, 368 malaria-suspected febrile patients (55.4% female, aged 5-80 years old, mean ± SD = 27.28 ± 14.0) participated. The prevalence of anti-chikungunya virus IgM antibodies, indicating acute infection, was 47.8%, while the prevalence of IgG antibodies, indicating previous exposure, was 6.3%. Nonmarried participants were found to be more likely to have acute chikungunya virus infection (AOR = 2.34, 95% CI: 1.141-4.964), and back pain was associated with higher likelihood of acute infection (AOR = 1.785; 95% CI: 1.078-2.954). About 10.6% of the participants tested positive for Plasmodium parasite infection, with P. falciparum (84.6%) being the most common, followed by P. vivax (10.3%) and mixed (5.1%) infections. The study revealed a high seroprevalence of acute chikungunya virus infection among febrile patients in the Afar Region, highlighting the importance of regular screening for arbovirus infection in febrile patients to control and mitigate chikungunya spread.

Spatial variation and geographical weighted regression analysis to explore open defecation practice and its determinants among households in Ethiopia.

In Ethiopia, recent evidence revealed that over a quarter (27%) of households (HHs) defecated openly in bush or fields, which play a central role as the source of many water-borne infectious diseases, including cholera. Ethiopia is not on the best track to achieve the SDG of being open-defecation-free by 2030. Therefore, this study aimed to explore the spatial variation and geographical inequalities of open defecation (OD) among HHs in Ethiopia. This was a country-wide community-based cross-sectional study among a weighted sample of 8663 HHs in Ethiopia. The global spatial autocorrelation was explored using the global Moran's-I, and the local spatial autocorrelation was presented by Anselin Local Moran's-I to evaluate the spatial patterns of OD practice in Ethiopia. Hot spot and cold spot areas of OD were detected using ArcGIS 10.8. The most likely high and low rates of clusters with OD were explored using SaTScan 10.1. Geographical weighted regression analysis (GWR) was fitted to explore the geographically varying coefficients of factors associated with OD. The prevalence of OD in Ethiopia was 27.10% (95% CI: 22.85-31.79). It was clustered across enumeration areas (Global Moran's I = 0.45, Z-score = 9.88, P-value ≤ 0.001). Anselin Local Moran's I analysis showed that there was high-high clustering of OD at Tigray, Afar, Northern Amhara, Somali, and Gambela regions, while low-low clustering of OD was observed at Addis Ababa, Dire-Dawa, Harari, SNNPR, and Southwest Oromia. Hotspot areas of OD were detected in the Tigray, Afar, eastern Amhara, Gambela, and Somali regions. Tigray, Afar, northern Amhara, eastern Oromia, and Somali regions were explored as having high rates of OD. The GWR model explained 75.20% of the geographical variation of OD among HHs in Ethiopia. It revealed that as the coefficients of being rural residents, female HH heads, having no educational attainment, having no radio, and being the poorest HHs increased, the prevalence of OD also increased. The prevalence of OD in Ethiopia was higher than the pooled prevalence in sub-Saharan Africa. Tigray, Afar, northern Amhara, eastern Oromia, and Somali regions had high rates of OD. Rural residents, being female HH heads, HHs with no educational attainment, HHs with no radio, and the poorest HHs were spatially varying determinants that affected OD. Therefore, the government of Ethiopia and stakeholders need to design interventions in hot spots and high-risk clusters. The program managers should plan interventions and strategies like encouraging health extension programs, which aid in facilitating basic sanitation facilities in rural areas and the poorest HHs, including female HHs, as well as community mobilization with awareness creation, especially for those who are uneducated and who do not have radios.

Susceptibility status of Aedes aegypti (Diptera: Culicidae) to public health insecticides in Southern Afar Region, Ethiopia.

Mosquito-borne viral diseases such as dengue fever, chikungunya, and yellow fever have been documented in Ethiopia since the 1960s. However, the efficacy of public health insecticides against Aedes aegypti that transmits these viruses remains poorly understood in the country, particularly in the Afar Region. Thus, the aim of the study was to assess the susceptibility status of Ae. aegypti to deltamethrin, permethrin, alpha-cypermethrin, pirimiphos-methyl, bendiocarb, and propoxur insecticides. Larvae and pupae of Aedes species were collected from Awash Arba, Awash Sebat, and Werer towns of the Afar Region of Ethiopia during July-October 2022, brought to the Aklilu Lemma Institute of Pathobiology, insectary and reared to adults. Non-blood-fed, 3-5 days-old females Ae. aegypti were exposed to pyrethroid, carbamate, and organophosphate insecticide impregnated papers in tube test following the standard guidelines. Knockdown rates were noted at 10 minutes interval until one hour. The mortality in mosquitoes was recorded 24 hours after 60 minutes of exposure. The mortality rates of Ae. aegypti exposed to propoxur were 87% in all the study towns. Similarly, 88% mortality in Ae. aegypti was recorded when tested with bendiocarb in Awash Sebat and Awash Arba towns. Suspected resistance of Ae. aegypti (95% mortality) to alpha-cypermethrin was observed in Awash Arba town. However, Ae. aegypti collected from all the three sites was observed to be susceptible to deltamethrin, permethrin, and pirimiphos-methyl. Ae. aegypti was resistant to 0.1% bendiocarb and 0.1% propoxur and possibly resistant to 0.05% alpha-cypermethrin. On the other hand, it was susceptible to 0.05% deltamethrin, 0.75% permethrin, and 0.25% pirimiphos-methyl. Thus, vector control products with deltamethrin, permethrin, and pirimiphos-methyl can be used in the control of adult Ae. aegypti in the Afar Region of Ethiopia. However, further studies should be carried out to evaluate the susceptibility status of Ae. aegypti to alpha-cypermethrin in the Awash Arba area.

Seropositivity, Comparison Between the Efficiency of Serological Tests and Risk Factors of Brucella Infection in Small Ruminants with History of Abortion in the Afar Region of North-Eastern Ethiopia.

Brucellosis is one of the most important reproductive diseases that cause abortion and breeding failure in small ruminants in Ethiopia. Therefore, our objective was to detect the seropositivity and risk factors of Brucella infection in small ruminants with history of abortion using modified RBPT, cELISA, and CFT in the Amibara district of the Afar Region, Ethiopia. Sera were collected from 226 animals (195 goats and 31ewes) and assessed for seropositivity of Brucella infection using modified RBPT, CFT, and competitive ELISA. The overall seroprevalence was 12.0% (27 out of 226), 7.5% (17 out of 226), and 26.5% (60 out of 226) by mRBPT, CFT, and cELISA, respectively. Out of 27 sera that were reactive by mRBPT, 17 (63.0%) were also reactive by (CFT). Out of the 17 sera that were reactive by CFT and mRBPT, 14 (82.4%) were reactive by cELISA. Out of the 29 sera that were non-reactive by both mRBPT and CFT, 10 (34.5%) were found reactive by cELISA. Out of the 226 sera that were tested by both mRBPT and cELISA, 20 (8.9%) were reactive by both tests, while 159 (70.4%) were non-reactive by both tests. The percentage of test agreement (79.2%) between mRBPT and cELISA was poor (k=0.353). High seropositivity for Brucella infection was significantly associated with the presence of retained placenta in the studied animals (adjusted OR=2.2, 95% CI, 1.1-4.4, P=0.030) as detected by cELISA. The current study revealed that a cELISA-based seroepidemiological survey increases the likelihood of detecting individuals with brucellosis and provides reliable evidence for mRBPT. Furthermore, there was a significant association between seropositivity for Brucella infection and retained placenta. These findings emphasize the necessity for proactive measures to reduce the economic impact of brucellosis and mitigate the risk of zoonotic transmission.

Spatial variations and determinants of bottle feeding among children aged 0-23 months in Ethiopia in 2019: A spatial and multi-level analysis.

Bottle feeding should be avoided since it interferes with optimal breastfeeding and it causes diarrheal-related morbidity and mortality. Despite the WHO's recommendation that children to avoid bottle feeding, it is still widely practiced in developing countries including our country, Ethiopia. Therefore, this study aimed to assess the spatial variations, and determinants of bottle feeding among children aged 0-23 months using the recent demographic and health survey data for Ethiopia. A secondary data analysis was conducted using the 2019 Ethiopian mini demographic and health survey data. The total weighted sample of 2067 children aged 0-23 months was included in this study. Spatial analysis was done to identify the hotspot areas of bottle feeding among children in Ethiopia. Multivariable multilevel logistic regression was used to identify predictors of bottle feeding. The spatial analysis was done using ArcGIS 10.7 and Sat Scan 9.6 software. The prevalence of bottle feeding among children aged 0-23 months was 21.52% with 95% CI(19.80%, 23.34%). Age of the child from 6-11 months, and 12-23 months age, having secondary and above education [AOR = 2.09; 95%CI; 1.31, 3.32], being from middle and rich household [AOR = 2.14; 95%CI; 1.37, 3.34] and [AOR = 2.30; 95%CI; 1.46, 3.63], and twin birth [AOR = 8.06; 95%CI; 2.87, 22.58] were significant predictors of bottle feeding. Hotspot areas of bottle feeding were observed in Addis Ababa, Dire Dawa, Harari, and Afar regions of Ethiopia. Bottle feeding practice was found to be spatially clustered in Ethiopia. Education, wealth index, parity, and child's age were significant predictors of bottle feeding. Hotspot areas of bottle feeding were observed in Addis Ababa, Dire Dawa, Harari, and Afar regions. Special attention should be directed towards mothers residing in hotspot areas, educated mothers, mothers of multiple births, and mothers from rich households through community education programs focused on child feeding practices to reduce the practice of bottle-feeding in Ethiopia.

Exploring Spatial Variation of Women’s Tetanus Vaccination in Ethiopia: Spatial Analysis of Ethiopian Demographic and Health Survey 2016

Tetanus is a bacterial infection that causes painful muscular contractions throughout the body, usually starting in the jaw. Every year, 15,000 to 30,000 maternal deaths occur due to tetanus related to the delivery process. Exploring variations of women’s tetanus immunization is crucial for programmers’ planning and monitoring. As a result, this study aims to evaluate the spatial distribution of women’s tetanus vaccination coverage and risk areas of women’s tetanus vaccination clustering in Ethiopia. The study used Ethiopian Demographic and Health Survey data, which was conducted in 2016 using the Ethiopia Population and Housing Census 2007 sampling frame. From 15,683 women aged 15 to 49, a sample of 7,193 women was selected using eligible criteria. This study used spatial data analysis. To determine geographical danger zones for tetanus vaccination of women, cluster, hotspot analysis, spatial interpolation, and spatial scan statistics were used. At the regional level of Ethiopia, tetanus vaccination was spatially clustered (Global Moran’s I = 0.066, p = .0001). Western Tigray, eastern SNNP, and northern Oromia were identified as hotspots of poor tetanus vaccine coverage, whereas western Oromia, Afar, and southeast Amhara regions were designated as non-risky areas of Ethiopia. The spatial Bayesian kriging interpolation analysis predicted high-risk areas were the southwestern and eastern parts of Oromia, western Tigray, Harari, and Dire Dawa Western Tigray, the eastern SNNP, southern Amhara, and northern Oromia have been recognized as a significant hotspot. Health workers, programmers, government, and non-governmental organizations in Ethiopia will implement spatially based strategic interventions for women’s tetanus immunization.

Geographical variation in hotspots of stunting among under-five children in Ethiopia: A geographically weighted regression and multilevel robust Poisson regression analysis.

Childhood stunting is a global public health concern, associated with both short and long-term consequences, including high child morbidity and mortality, poor development and learning capacity, increased vulnerability for infectious and non-infectious disease. The prevalence of stunting varies significantly throughout Ethiopian regions. Therefore, this study aimed to assess the geographical variation in predictors of stunting among children under the age of five in Ethiopia using 2019 Ethiopian Demographic and Health Survey. The current analysis was based on data from the 2019 mini Ethiopian Demographic and Health Survey (EDHS). A total of 5,490 children under the age of five were included in the weighted sample. Descriptive and inferential analysis was done using STATA 17. For the spatial analysis, ArcGIS 10.7 were used. Spatial regression was used to identify the variables associated with stunting hotspots, and adjusted R2 and Corrected Akaike Information Criteria (AICc) were used to compare the models. As the prevalence of stunting was over 10%, a multilevel robust Poisson regression was conducted. In the bivariable analysis, variables having a p-value < 0.2 were considered for the multivariable analysis. In the multivariable multilevel robust Poisson regression analysis, the adjusted prevalence ratio with the 95% confidence interval is presented to show the statistical significance and strength of the association. The prevalence of stunting was 33.58% (95%CI: 32.34%, 34.84%) with a clustered geographic pattern (Moran's I = 0.40, p<0.001). significant hotspot areas of stunting were identified in the west and south Afar, Tigray, Amhara and east SNNPR regions. In the local model, no maternal education, poverty, child age 6-23 months and male headed household were predictors associated with spatial variation of stunting among under five children in Ethiopia. In the multivariable multilevel robust Poisson regression the prevalence of stunting among children whose mother's age is >40 (APR = 0.74, 95%CI: 0.55, 0.99). Children whose mother had secondary (APR = 0.74, 95%CI: 0.60, 0.91) and higher (APR = 0.61, 95%CI: 0.44, 0.84) educational status, household wealth status (APR = 0.87, 95%CI: 0.76, 0.99), child aged 6-23 months (APR = 1.87, 95%CI: 1.53, 2.28) were all significantly associated with stunting. In Ethiopia, under-five children suffering from stunting have been found to exhibit a spatially clustered pattern. Maternal education, wealth index, birth interval and child age were determining factors of spatial variation of stunting. As a result, a detailed map of stunting hotspots and determinants among children under the age of five aid program planners and decision-makers in designing targeted public health measures.

Nationwide Geospatial Analysis to Identify Variations in Primary Cardiovascular Risk in Ethiopia.

Cardiovascular disease (CVD) varies across regions due to socioeconomic, cultural, lifestyle, healthcare access, and environmental factors. To find geographical variations in 10-year primary CVD risk and assess the impact of contextual factors on CVD risk. Data from 2658 Ethiopians aged 40 to 69 years with no previous CVD who participated in a nationally representative World Health Organization (WHO) STEPS survey in 2015 were included in the analysis. The mean 10-year CVD risk for 450 enumeration areas (EA) was used to identify spatial autocorrelation (using Global Moran's I) and CVD hot spots (using getas-Ord Gi*). Geographically Weighted Regression (GWR) analysis quantified the relationship between mean 10-year CVD risk and climate-related factors across areas. The spatial autocorrelation analysis identified significant spatial variation in the 10-year CVD risk at the EA level, with a global Moran's I value of 0.016. Statistically significant hot spot areas with 10-year CVD risk were identified in Addis Ababa (the capital), Benishangul Gumuz, SNNPR (Southern Nations, Nationalities, and Peoples' Region), Amhara, Afar, Oromia, and Hareri regions. In a multivariable GWR analysis, average water vapor pressure was a statistically significant explanatory variable for the geographical variations in 10-year CVD risk. Hot spot areas for 10-year CVD risk were identified across numerous country regions rather than concentrated in a specific region. Alongside these hot spot areas, regions with a higher annual water vapor pressure (humidity) were identified as geographical targets for CVD prevention.

Seroprevalence and Co-Circulation of Rift Valley Fever Virus and West Nile Fever Virus in Livestock Population of Afar Region, Northeast Ethiopia.

The distribution, epidemiology, and socioeconomic impact of Rift Valley fever (RVF) and West Nile (WN) viruses are poorly known in areas of sub-Saharan countries like Ethiopian pastoral region. The human and livestock density in the area has increased greatly in recent years, but little work has been done on arboviral diseases and their potential impact on human and livestock health. The aim of this study was to detect the circulation of zoonotic arboviruses such as Rift Valley fever virus and West Nile viruses in the livestock population and to estimate seroprevalence in Afar pastoral area northeast Ethiopia. Cross-sectional serological survey was carried out in 736 serum samples from which cattle (224), camel (155), goats (121), sheep (144), and donkeys (92) were tested for the presence of anti-RVFV and anti-WNV IgG using a competitive enzyme-linked immunosorbent assay (c-ELISA) in two purposively selected districts of the Afar region. The present study revealed a 9.1% (95% CI = 8.86-9.29) seroprevalence of co-circulation of RVF and WNV. High 32/155 (20.7%) seroprevalence of co-circulation was seen in camels, followed by goat 14/121 (11.6%), cattle 16/224 (7.14%), and sheep 5/144 (3.5%), respectively, and higher 41/421 (9.7%) seroprevalence of co-circulation was observed in Amibara district than Haruka district. Camels were seven times (OR: 7.016, 95% CI = 2.639-18.653) more likely to be seropositive for the co-circulation than sheep (p ≤ 0.001). Livestock herds found in Amibara district were 1.2 times (OR: 1.165, 95% CI = 0.680-1.996) more likely to be seropositive for RVFV infection than those in Haruka areas. Given the co-occurrence of RVFV and WNV circulations, along with often suboptimal human and animal health surveillance in many similar areas' attention should be given. Investigation of the potential socioeconomic and health impacts of zoonotic arbovirus infections in such areas is crucial. Since both RVFV and WNFV are transmitted through a mosquito vector, avoiding mosquito bites is the primary method of prevention.