You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy and New Technology III1 Apr 20122180 ERASER LASER ENUCLEATION OF THE PROSTATE (ELEP) VERSUS BIPOLAR TURP Lukas Lusuardi, Tobias Schätz, Stephan Hruby, Manuela Sieberer, Reinhold Zimmermann, and Günter Janetschek Lukas LusuardiLukas Lusuardi Salzburg, Austria More articles by this author , Tobias SchätzTobias Schätz Salzburg, Austria More articles by this author , Stephan HrubyStephan Hruby Salzburg, Austria More articles by this author , Manuela SiebererManuela Sieberer Salzburg, Austria More articles by this author , Reinhold ZimmermannReinhold Zimmermann Salzburg, Austria More articles by this author , and Günter JanetschekGünter Janetschek Salzburg, Austria More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.2353AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Goal of the present study was to ascertain safety and efficacy of a 1,318-nm diode laser for transurethral enucleation of the prostate comparing it to the “gold standard” bipolar transurethral resection of the prostate (TURP). The Eraser laser has been successfully used to resect lung metastasis. It has been recognized to cut and coagulate vascular rich tissue safely and effectively. We describe a prospective randomized trial of Eraser enucleation (ELEP) of the prostate versus TURP. METHODS A total of 100 patients with lower urinary tract symptoms suggestive of bladder outlet obstruction and a mean prostate size of 61.3 ml on transrectal ultrasound were randomized to ELEP or bipolar TURP. Patients were assessed preoperatively and at 1 and 6 months postoperatively. RESULTS ELEP was equivalent to bipolar TURP in terms of improvement in IPSS, maximal flow rates and quality of life. ELEP was significantly superior to bipolar TURP for measured blood loss (114.54 ± 95.02 vs 389.80 ± 138.60ml, p<0.05), catheter time (31.70 ± 7.79 vs 63.74 ± 13.72 hours, p<0.05) and hospital time (43.15 ± 14.56 vs 89.10 ± 10.73 hours, p<0.05). Using the validated Clavien-Dindo system there were 3 grade Id complications and 1 grade II complication. CONCLUSIONS ELEP and bipolar TURP were equally safe and effective for relieving bladder outflow obstruction and lower urinary tract symptoms. ELEP has the advantage of less blood loss, shorter catheter time and hospital stay. Table 1. Perioperative data Mean ELEP+/− SD Mean TURP+/− SD p Value Operative time (min) 68.00 +/− 10.22 59.41 +/− 4.4 <0.05 Enucleation/resection time (min) 45.60 +/− 6.45 59.42 +/− 4.4 <0.05 Morcellation (min) 20.90 +/− 6.51 Resected wt (gm) 32.10 +/− 9.34 32.16 +/− 8.74 0.989 Retrieval rate (gm/min) 0.44 +/− 0.07 0.43 +/− 0.08 0.674 Hemoglobin postop.(gm/dl) 14.69 +/− 0.97 13.122 +/− 0.75 <0.05 Blood loss (ml) 114.54 +/− 95.02 389.80 +/− 138.60 <0.05 HB loss (gm/dl) 0.24 +/− 0.16 0.61 +/− 0.71 <0.05 Blood loss/resected tissue (ml/gm) 6.05 +/− 3.86 10.90 +/− 3.37 <0.05 Bleeding velocity (ml/min) 2.89 +/− 1.41 5.39 +/− 0.76 <0.05 Catheter time (hours) 31.70 +/− 7.79 63.74 +/− 13.72 <0.05 Hospital time (hours) 43.15 +/− 14.56 89.10 +/− 10.73 <0.05 Intraoperative irrigation volume (l) 21.17 +/− 2.84 14.07 +/− 1.60 <0.05 © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e879 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Lukas Lusuardi Salzburg, Austria More articles by this author Tobias Schätz Salzburg, Austria More articles by this author Stephan Hruby Salzburg, Austria More articles by this author Manuela Sieberer Salzburg, Austria More articles by this author Reinhold Zimmermann Salzburg, Austria More articles by this author Günter Janetschek Salzburg, Austria More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...