The rapid advancement of Health Information Technology (HIT) has revolutionized cancer care, introducing new capabilities in early detection, individualized treatment, and data security. This paper reviews the key HIT innovations that have reshaped oncology, including the widespread adoption of Electronic Health Records (EHRs), the use of artificial intelligence (AI) in diagnostic processes, and the application of telemedicine and predictive analytics to improve treatment planning. These technologies have enabled earlier and more accurate diagnoses, expanded access to care, and facilitated data-driven, personalized treatment strategies. In parallel, this review addresses the importance of safeguarding sensitive patient data, focusing on encryption, anonymization techniques, and the regulatory frameworks like HIPAA and GDPR that ensure data privacy. Finally, the paper discusses future directions for HIT, particularly the potential of AI-driven decision support systems, real-time data analytics, and privacy-enhancing algorithms to further advance cancer care, creating a more secure, efficient, and patient-centered healthcare system.