AbstractDue to the increasing importance of advanced systems, whose development calls for interdisciplinary and integrative approaches, and fundamental changes in the work environment, leaders are required to have a wide range of competences. Therefore, the aim of this work is to identify competences of future leaders, that are specifically relevant in Advanced Systems Engineering (ASE). Thus, professional, social, methodological, and self competences developed by a literature review are validated through expert interviews and prioritized by a survey. The insights are then presented in a competence portfolio including 30 areas of competences. The portfolio consists of areas of competence that are either relevant in the context of ASE (e.g. intercultural and interdisciplinary competence), New Work (e.g. competence to empower employees) or are relevant to leaders in general. It was possible to add further aspects that are necessary in ASE to the aspects from the literature review. The experts interviewed emphasized various aspects of interdisciplinary work and made clear that in future, leaders should place their employees at the heart of their activities and empower them according to their strengths and weaknesses.