Adult Human Females Research Articles

MESONEPHRIC REMNANTS IN THE CERVIX

I T IX well known that certain portions of the mesonephros may persist near the ovary and in the broad ligament and the vagina of ‘the adult human female. That fetal remnants of mesonephric origin may persist in the uterine cervix is less commonly realized. From time to time reports have appeared in the European literature commenting on the development of tumors arising from mesonephric residues in the cervix. Meyer’w3 has presented factual data establishing the embryonic source of such neoplasms as being from the cervical portion of the mesonephric duct. With the exception of Wolfe’s case reports several years ago,4 the American literature has contained no reference to this unique and unusual problem. It should be a matter of interest shared in common by t,he clinician, the gynecologic histopathologist, and the embryologist. This is particularly true when it is realized that mesonephric remnants in the cervix may cause confusion in the histologic study of surgically excised tissues and that they may give rise to bizarre tumors which can be either benign or malignant. Because of the paucity and the relative inaccessibility of available information on the subject, it has seemed worth while to make this presentation an attempt to portray in definitive fashion the embryology, the histology, and the microscopic pathology of mesonephric remnants in the uterine cervix. In order to accomplish this the literature has been reviewed, serially sectioned tissues have been studied, and sections from 1,192 surgically excised cervices in the gynecologic laboratory at Northwestern Cniversity Medical School (comprising tissues from Passavant Memorial and Wesley Memorial Hospitals) have been examined.

Mesonephric remnants in the cervix

I T IX well known that certain portions of the mesonephros may persist near the ovary and in the broad ligament and the vagina of ‘the adult human female. That fetal remnants of mesonephric origin may persist in the uterine cervix is less commonly realized. From time to time reports have appeared in the European literature commenting on the development of tumors arising from mesonephric residues in the cervix. Meyer’w3 has presented factual data establishing the embryonic source of such neoplasms as being from the cervical portion of the mesonephric duct. With the exception of Wolfe’s case reports several years ago,4 the American literature has contained no reference to this unique and unusual problem. It should be a matter of interest shared in common by t,he clinician, the gynecologic histopathologist, and the embryologist. This is particularly true when it is realized that mesonephric remnants in the cervix may cause confusion in the histologic study of surgically excised tissues and that they may give rise to bizarre tumors which can be either benign or malignant. Because of the paucity and the relative inaccessibility of available information on the subject, it has seemed worth while to make this presentation an attempt to portray in definitive fashion the embryology, the histology, and the microscopic pathology of mesonephric remnants in the uterine cervix. In order to accomplish this the literature has been reviewed, serially sectioned tissues have been studied, and sections from 1,192 surgically excised cervices in the gynecologic laboratory at Northwestern Cniversity Medical School (comprising tissues from Passavant Memorial and Wesley Memorial Hospitals) have been examined.

The detailed anatomy of the paraurethral ducts in the adult human female

The material studied consisted of serial sections and wax model reconstructions of adult human female urethras. As a result of this study, a concept of the anatomy and histology of the paraurethral ducts is presented. It would appear that these ducts are not constant in number or location; that they not only form extensive ramifications throughout the tissues about the distal urethra, but that they may also extend to within a short distance of the bladder; and that the often numerous ducts terminate in tubular glands which are lined for the most part by columnar epithelium. This epithelium has some, although limited, secretory activity.The role which the paraurethral ducts may play in the etiology of lesions of the urethra and anterior vaginal wall is discussed.

The weight of the principal components of the normal hypophysis cerebri of the adult human female

The weight of the principal components of the normal hypophysis cerebri of the adult human female

Studies in the physiology and pharmacology of the human vagina: Drs. R. D. Templeton, Irving Stein and Sydney Schochet presented a paper entitled

1.1. Spontaneous rhythmic contractions are present in the vagina of adult human females during the childbearing period and are absent in those past the menopause.2.2. The rhythmic contractions are more marked during the week after the menstrual period (postmenstrual).3.3. Vaginal contractions are not induced by contractions of an adjacent organ (bladder).4.4. Pituitrin and ergotoxin cause increase in rate and amplitude of the vaginal contractions.