Adult Eating Disorder Patients Research Articles

Plasma homocysteine levels in female patients with eating disorders

To examine plasma homocysteine, vitamin B(12), and folate levels in females with restricting and bingeing/purging eating disorders (EDs). Adolescent and adult female patients were compared to appropriate control groups with regard to plasma homocysteine levels. The plasma homocysteine level of the adult ED patients was higher than that of controls for all age groups examined. In adolescents, no significant difference was found comparing ED patients younger than 16 years of age to control data, whereas in the 16-20 year age group, the plasma homocysteine level was significantly higher among the ED group, regardless of the type of ED. Vitamin B(12) and folate levels were within normal limits in all ED groups. Elevated plasma homocysteine levels were found in adult and older adolescent female ED patients (but not in younger adolescents) compared to controls. This finding is not related to deficiencies in vitamin B(12) or folate.

Childhood onset neuropsychiatric disorders in adult eating disorder patients

Autism spectrum disorders (ASD) have been suggested to be overrepresented in anorexia nervosa. This study aimed to explore the comorbidity of ASD and other childhood onset neuropsychiatric disorders (COND) [attention-deficit/hyperactivity disorder (AD/HD) and tic disorders] in a group of severe eating disorder (ED) patients. Thirty female ED patients from a specialist hospital clinic were examined on measures tapping into COND and personality disorders. In our group of longstanding ED, 53% had at least one COND diagnosis; 23% had ASD, 17% had AD/HD, and 27% had a tic disorder. These preliminary data suggest that COND may be common in patients with severe ED and should be kept in mind when treating these patients.

Adults with chronic eating disorders. Two-year follow-up after inpatient treatment

Objective The aims of this prospective study were (1) to report on the 2-year outcome of chronically ill adult eating disorder patients, (2) to investigate whether a specialized inpatient treatment might influence the course of the illness, and (3) to search for prognostic factors. Method Seventy-two patients were treated in a 4–5-month specialized group treatment programme for chronically ill adults with eating disorders. Sixty-five (90%) with mean age of 30 years were available for the follow-up assessment. Results Forty-six (71%) patients had improved at the 2-year follow-up and 17 (26%) did not meet diagnostic criteria for an eating disorder. The symptom reductions per time were statistically significantly larger during the inpatient period compared to the waiting-list and follow-up periods. No significant predictors of treatment outcome were found. Patients with avoidant personality disorder had a higher level of distress at all times, but improved at the same rate as the others. Conclusion At the 2-year follow-up, there were substantial reductions in eating disorder symptoms and general psychiatric symptoms. Most of the improvement occurred during inpatient treatment, which might be an option for chronic eating disorders. Copyright © 2005 John Wiley & Sons, Ltd and Eating Disorders Association.

Do adolescent anorexia nervosa patients have deficits in emotional functioning?

Adult eating disorder patients have been characterised by alexithymia. We investigated whether adolescent eating disorder patients also show deficits in emotional functioning. To measure emotional functioning a questionnaire (the TAS) and an emotion recognition test were administered to 30 eating disorder (ED) adolescent girls and 31 healthy controls (HC), matched for age, education, and social status. Non-emotional, cognitive parallel tasks were administered on the same occasion to find out whether a possible deficit was emotion-specific or of a more general cognitive nature. The ED patients scored higher on the TAS and performed worse on the emotion recognition test, but no differences between the groups were found on the non-emotional cognitive instruments. It was concluded that adolescent eating disorder patients, just like adult eating disorder patients, are characterised by alexithymia and show specific deficits in emotional functioning. The implications of these findings are discussed.