Administration Of Vedolizumab Research Articles

Considerations for Creating a Protocol for Vedolizumab Infusions

Vedolizumab (Entyvio, Takeda Pharmaceuticals America, Inc., Deerfield, IL) is one of several treatment options for the management of ulcerative colitis and Crohn's disease. It is a recombinant humanized anti–alpha-4-beta-7 integrin monoclonal antibody. This biologic immunotherapy is used in patients who have failed or achieved inadequate response to the different therapies currently available for these disease processes. Certain considerations include monitoring for tuberculosis, and the administration of immunizations before the initiation of therapy. A protocol for the safe administration of vedolizumab at New York University Center for Musculoskeletal Care Infusion Center is based on current prescribing guidelines.