This study reveals the dynamic compressive deformation anisotropy among 316L stainless steel fabricated via wire and arc additive manufacturing process(WAAM). Cylindrical samples extracted from as-built WAAM 316L plate with 35°, 45°, 55°and 90° from scanning direction, were referred to as <111>, <110>, <112> and <100> crystallographic orientations hereinafter, which had been confirmed through backscattered diffraction. Cylindrical samples were subjected to dynamic tests by a split Hopkinson pressure bar. The corresponding mechanical behaviors and deformed microstructures are associated. There are approximately 10% higher dynamic flow stresses from the <111> samples than other samples during dynamic tests at strain rates less than 3500 s−1, which can be attributed to lower density of thinner deformation twins. The lower tendency towards deformation twinning in <111> samples arises from the increase of effective stacking fault energy. WAAM 316L presents an anisotropy of resistance to adiabatic shearing, of which the order is < 100>, <110>, <112> and <111>. Two adiabatic shear bands(ASB) in <111> sample present distinct orientation characters, where the sub-grains in the first ASB show <111> and <112>-fiber while that in the subsequent one take <110>-fiber. This micro-texture discrepancy from two ASBs could be contributed to the precondition change of macro texture in the matrix which give birth to.