Adhesion Research Articles

Heat transfer origin of adhesion behaviors between liquid-aluminum and solid aluminum/silicon interfaces

Liquid-aluminum tends to adhere to some surfaces rather than others, and the underlying mechanism of the differences in adhesion of liquid-aluminum on different surfaces is still unclear. This manuscript takes liquid-aluminum/aluminum and liquid-aluminum/silicon interfaces as research objects, revealing that solid aluminum surface is aluminophilic but the solid silicon surface is aluminophobic, mainly due to differences in interfacial thermal conductance (ITC) between two interfaces. We also investigate effect of surface temperature on adhesion characteristics of liquid-aluminum on aluminum/silicon surfaces, and decode the reasons from lattice integrity and phonon spectra. It is shown that vibrational state with intact lattice excites fewer low frequency phonons with increasing surface temperature, resulting in a decrease in ITC and thus adhesion force. In diffusion state where lattice is fractured resulting from high temperature, interfacial adhesion is increased due to surface defects.

Study on the wetting characteristics of liquid-Al/ SiO2 interface with Si content in liquid-Al

Aiming to address the issue of aluminum slag adhering to the interior walls of vacuum lifting ladles in the aluminum electrolysis industry, Molecular dynamics simulations are employed to investigate the wetting behavior and adhesion characteristics of aluminum droplets on silica surfaces. Our findings indicate that with an increase in silicon content within the droplets, wetting diminishes and complete wetting of the silica substrate by aluminum droplets is not achieved. The presence of silicon reduces both the melting point temperature and surface tension of aluminum droplets, leading to a significant increase in contact angle and a corresponding decrease in wettability. Moreover, an elevated silicon content within molten aluminum droplets substantially decreases their interaction energy with the substrate surface. The virtual wall method is applied to examine average separation force and work of separation for detaching aluminum droplets from the substrate, revealing that adhesion characteristics are predominantly governed by mutual adhesive forces. This paper presents an atomic-level analysis elucidating how silicon as an alloying element influences adhesion between liquid aluminum and solid surfaces.

Shear bond strength between dental adhesive systems and an experimental niobium-based implant material

This study aimed to investigate adhesive shear bond strength (SBS) on an ultrafine-grained niobium alloy (UFG-Nb) that is a potential dental implant material. SBS of three adhesive systems combined with three composites to UFG-Nb was compared to corresponding SBS to Ti-6Al-4V and to zirconia. Specimens of the substrates UFG-Nb, Ti-6Al-4V and zirconia with plane surfaces were sandblasted with Al2O3, cleaned and dried. Three adhesive systems (Futurabond U, Futurabond M + , Futurabond M + DCA; all VOCO GmbH, Cuxhaven, Germany) were applied each on specimens of each substrate and light cured. One composite (BifixSE, BifixQM, GrandioSO; all VOCO GmbH) was applied and light cured resulting in 27 groups (n = 10) for all substrate-adhesive-composite-combinations. SBS was measured after 24 h of storage. To simulate aging equally prepared specimens underwent 5000 thermocycles before SBS measurement. There was no significant difference in SBS within the non-aged groups. Among the artificially aged groups, GrandioSO-groups showed a greater variance of SBS than the other composites. All significant differences of corresponding UFG-Nb-, Ti-6Al-4V- and zirconia-groups with same adhesive-composite-combination (ACC) were observed between UFG-Nb and zirconia or Ti-6Al-4V and zirconia but never between the two metallic substrates. The similarity between these materials might show in their adhesive bonding behavior. As there were no differences comparing corresponding groups prior to and after artificial aging, it can be concluded that aging does not affect SBS to UFG-Nb, Ti-6Al-4V and zirconia using the tested ACCs. Adhesive bonding of established ACCs to UFG-Nb is possible resulting in SBS comparable to those on Ti-6Al-4V and zirconia surfaces.Graphical

Developing biomimetic PVA/PAA hydrogels with cellulose nanocrystals inspired by tree frog structures for superior wearable sensor functionality

This study developed a wearable sensor device featuring biomimetic structures inspired by tree frog toe pads to measure shoulder joint movements effectively. A PVA/PAA double-network hydrogel was formulated by mixing PVA and PAA in a 3:7 ratio, resulting in a Young's modulus of 7.2 kPa, closely matching human skin's mechanical properties. To enhance moisture retention, the hydrogel was supplemented with 20 mL glycerin, increasing its weight retention rate to 95 % after 28 days, a 5.6-fold improvement over glycerin-free hydrogels. Additionally, the incorporation of 0.2 wt% cellulose nanocrystals (CNC) increased the cross-linking density, reducing the swelling ratio from 124 % to 106 % and minimizing the impact of swelling cycles on mechanical properties from 22 % to 4 %. Treefrog-inspired microstructures were fabricated on the sensor surface using laser cutting and casting techniques, significantly enhancing adhesion under humid conditions, with normal, lateral, and peel-off adhesion forces improving by 500, 700, and 700 %, respectively. The sensor demonstrated accurate measurement of shoulder joint movements with an error margin of 6.3 % for polar angles (45°-135°) and 7.8 % for azimuth angles (0°-45°). The accompanying smartphone application provided real-time feedback, helping to prevent exercise injuries and improve user awareness and control of shoulder movements, making it suitable for both rehabilitation and athletic training.

Surface-Adhered Microbubbles Enhance the Resistance of ANAMMOX Granular Sludge to Sulfamethoxazole Stress.

The granule-based anammox process has been reported to be more resistant to the stress of antibiotics; however, the underlying resistance mechanism is still not fully understood. In this study, we found that more microbubbles stably adhered to the surface layer of anammox granular sludge (AnGS, Gs) operating under long-term sulfamethoxazole (SMZ) stress of 2 mg/L, compared to that in the control reactor (Gc). The difference in covering content can be up to over three times (1.0 ± 0.1% vs 0.3 ± 0.0%). Batch tests showed that the coverage ratio of microbubbles on Gs reached approximately 32.5%, which significantly reduced SMZ transfer into AnGS due to the adsorption of SMZ by bubbles, thus alleviating the inhibition of anammox bacterial activity by 36.5%. The adhesion force between the microbubbles and the surface layer of Gs was found to be largely enhanced by 75.0% compared to that of Gc. The increased hydrophobicity of surface layer due to the increased extracellular polymer substance (EPS, mainly proteins) content, and the larger capillary force of surface layer, owing to the unique micronano structure, were identified as key factors responsible for the stable adhesion of microbubbles on the Gs. Consequently, this study demonstrated the vital roles of the surface-adhered microbubbles in resisting the stress of SMZ and shed light on the regulation and development of robust granule-based anammox processes.

Adhesion performance and enhancement mechanism of FA/GGBFS based geopolymer modified bitumen and acidic aggregate

The primary challenge in utilizing acidic aggregates in bitumen mixtures lies in enhancing the adhesive bond between the bitumen and the acidic aggregates. In this manuscript, to investigate the adhesion of different geopolymer modified bitumen with acidic aggregates, fly ash geopolymer (FG), fly ash- ground granulated blast furnace geopolymer (SFG), and ground granulated blast furnace (SG) were prepared by fly ash (FA), ground granulated blast furnace (GGBFS) with alkali activator. The different geopolymers were characterized with SEM, XRD, FTIR. Different geopolymer modified bitumen was prepared by adding geopolymers into virginal bitumen. The conventional properties, viscosity, and rheological properties of modified bitumen were measured and analysed. The adhesion of bitumen to acidic aggregates was tested by Zeta potential test, the improved boiling water test and pull-off test. The results showed that the electronegativity of bitumen and acidic aggregates were weakened significantly by Na+ in skeletal structure of fly ash geopolymer. The high temperature stability of fly ash geopolymer modified bitumen was improved and the bond strength of bitumen with acidic aggregates increased remarkably with the addition of 9 % fly ash geopolymer.

Predicting lifetime of adhesive bonds for naval steel by time-temperature superposition

There is a lack of knowledge about the long-term behaviour of adhesive joints in the marine environment, and for hence, its reliability. The life cycle expected for a ship is twenty-five years and conduct duration tests would last decades. The importance and originality of this study are that it provides a methodology for predicting the durability of adhesive bonds. For this purpose, three adhesives for bonding naval steel were tested at several temperatures for determination of their shear strength on standard single-lap-joint specimens. Subsequently, using the time temperature superposition principle, these results were combined into one master curve for each adhesive that can be considered as a prediction method of the durability in a long-term period. The usual parametric models of Arrhenius and Williams-Landel-Ferry were used to obtain the master curve for each adhesive by manual shifting. The results were compared with those obtained applying an open-source software developed by the authors in R language, which specifically implements a non-parametric methodology based on the shift of the first derivative curves, following parameters of Explainable Artificial Intelligence. It was found a good correlation between both methodologies, supporting the durability lifetime obtained and therefore the applicability on ships of this adhesive technology.

Engineering tunable catch bonds with DNA

Unlike most adhesive bonds, biological catch bonds strengthen with increased tension. This characteristic is essential to specific receptor-ligand interactions, underpinning biological adhesion dynamics, cell communication, and mechanosensing. While artificial catch bonds have been conceived, the tunability of their catch behaviour is limited. Here, we present the fish-hook, a rationally designed DNA catch bond that can be finely adjusted to a wide range of catch behaviours. We develop models to design these DNA structures and experimentally validate different catch behaviours by single-molecule force spectroscopy. The fish-hook architecture supports a vast sequence-dependent behaviour space, making it a valuable tool for reprogramming biological interactions and engineering force-strengthening materials.

Offset-stoichiometric reflowable composite bonding method with adhesive for mitigating strict faying surface tolerances

Inherent susceptibility of adhesive bonds to miniscule quantities of contamination can cause undetectable weakened bonds. For this reason, the Federal Aviation Administration (FAA) places strict regulations on adhesively bonded joints in primary aircraft structures. To meet certification requirements aircraft manufactures resort to redundant load paths in the form of fasteners which inherently add weight to the structure and increase manufacturing time. In prior work, a secondary bonding technique called AERoBOND was developed, which utilized off-stoichiometric epoxy-matrix resins to facilitate reflow and diffusion of the resin within the joint interface during a secondary bonding/cure process, thus achieving a bond similar to a co-cured joint. However, the AERoBOND process required tight spatial tolerances between the two parts being joined. This study examined the utilization of conventional adhesive with the AERoBOND method to act as a filler in the joint line, effectively reducing the need for tight tolerances on the joining parts and serving as a flexible alternative for existing manufacturing processes. Ultrasonic inspection, optical microscopy, and ASTM International standard tests were performed to analyze the joints for defects and to quantify the mode-I and mode-II interlaminar fracture toughness and short beam strength of the proposed methodology with varying manufacturing parameters. The comprehensive results indicate that the AERoBOND+ method with and without surface preparation performs comparably to co-cured and conventional, adhesively bonded joints when secondary cured in an autoclave with 791 kPa of pressure. As an example, the AERoBOND+ panel without surface preparation bonded with 791 kPa of pressure (referred to as AB+3 throughout paper) had a mode-I fracture toughness (GIc) of 0.643 kJ/m2 and a mode-II fracture toughness (GIIc) of 4.000 kJ/m2 in the non-precracked condition and 4.218 kJ/m2 in the precracked condition at the adhesive-to-prepreg interface. These results were 96 %, 142 %, and 217 %, respectively, of a co-cured baseline panel (referred to as C1 throughout paper).

Influence of punch coating surface properties on sticking during the tableting process

Introduction The present study evaluates the sticking propensity of Uncoated steel, and chromium nitride (CrN), zirconium nitride (ZrN), titanium nitride (TiN) and Ultracoat punch coatings during the tableting process of microcrystalline cellulose (MCC) conducted on a Manesty® F3 single station tableting press. Methods Surface properties including surface roughness, surface free energy (SFE) and its components, the atomic percentage of surface polar functional groups and oxides measured with X-ray photoelectron spectroscopy were used to characterize the surface propensity to sticking. Results After five hours of tablet pressing, MCC powder particles were found to adhere to the TiN coated and the uncoated steel punches. Surface analysis show that surface roughness of all the tested punches was similar. The Lewis base SFE component (LB-comp) was found to govern the acid-base interactions of the tested surfaces, and its value was higher for punch surfaces affected by sticking. The surfaces exhibiting higher LB-comp are more prone to strong acid-base interactions with water molecules that evaporate from the powder bed during compression. Therefore, these surfaces adsorbed water and allow sticking through capillary adhesion force. Conclusion The total atomic percentage of the surface polar functional groups (PFG) and oxides was also high for the surfaces that stick to MCC during tableting, suggesting that hydrophilic molecules on the punch surface favor sticking.

Effect of propolis added to single-bottle adhesives on water permeation through the hybrid layer.

Water treeing and water droplets are observed within adhesive layers and on the hybridized surface after bonding sound dentin using single-bottle etch-and-rinse adhesives, indicating permeability of the hybrid layer to water. The aim of this study was to assess the efficacy of dentin sealing by adhesives containing propolis by quantifying the area of water transudation from dentinal tubules after dentin hybridization. Brazilian red propolis was added to experimental adhesive and Single Bond (3M/ESPE) adhesive; experimental adhesive and Single Bond without propolis were used as controls. Under simulated pulp pressure, two layers of adhesive were applied to etched human dentin discs. Three minutes after light-curing, the hybridized dentin surface was replicated, and epoxy resin replicas were created to obtain scanning electron microscope images. Data were evaluated using ANOVA and Tukey's test. Single Bond containing propolis significantly decreased water permeation through the hybrid layer compared with the control group. Three minutes after polymerization, the experimental adhesive without propolis had formed a permeable hybrid layer. The addition of Brazilian red propolis significantly reduced surface water on hybridized dentin in a concentration-dependent manner. Two-step etch-and-rinse adhesives containing propolis were effective in reducing water permeation through the hybridized dentin surface.

Human Mastication Analysis-A DEM Based Numerical Approach.

Mastication is an essential and preliminary step of the digestion process involving fragmentation and mixing of food. Controlled muscle movement of jaws with teeth executes crushing, leading towards fragmentation of food particles. Understanding various parameters involved with the process is essential to solve any biomedical complication in the area of interest. However, exploring and analyzing such process flow through an experimental route is challenging and inefficient. Computational techniques such as discrete element numerical modeling can effectively address such problems. The current work employs the Discrete Element Method (DEM) as a numerical modeling technique to simulate the human mastication process. Tavares and Ab-T10 breakage models coupled with Gaudin Schumann and Incomplete Beta fragment distribution models have been implemented to analyze the fragmental distribution of food particles. The effect of particle shape (spherical, polyhedron, and faceted cylinder), size (aspect ratio), and orientation (vertical and horizontal) on breakage and fragment distribution is analyzed. To account for the elastic-plastic behavior and moisture content in food particles, modifications has been made in breakage models by incorporating numerical softening factor and adhesion force. The study demonstrates how numerical modeling techniques can be utilized to analyze the mastication process involving multiple process parameters.

Superhydrophobicity induced antibacterial adhesion and durability of laser bidirectionally-textured zirconia surfaces with different inclination angles

Femtosecond laser bidirectional texturing with different laser energy densities and inclination angles was performed on zirconia (ZrO2) surfaces. The laser bidirectional texturing models under different inclination angles were constructed to predict the water contact angles (WCAs), and the superhydrophobicity induced antibacterial adhesion mechanism was analyzed. The results revealed that under the combined effect of the optimal laser energy density (7.0 J/cm2) and inclination angle (90°), the laser-textured ZrO2 surface could obtain a micro-nano dual-scale structure composed of periodic regular micro-cones and nanoparticles. This structure not only promoted the adsorption of carbon-containing hydrophobic groups from the stearic acid and the air to form a superhydrophobic surface with excellent chemical/mechanical durability and anti-fouling/self-cleaning abilities, but also minimized the contact area with the bacterial suspension (solid/liquid contact area ratio of 6 %) to enhance antibacterial ability. The optimal stearic acid-modified laser-textured ZrO2 surface exhibited an extremely low adhesive force (Fadhesive=6.69 μN) to the bacterial suspension, and thus achieved the highest antibacterial ratio of 85.3 %. This study is expected to enrich the application of ZrO2 ceramics in the medical field.

Fabrication of Surface-Enhanced Raman Scattering (SERS) Substrates in Analytical Science by Natural-inspired Materials: A Review

Surface-Enhanced Raman Scattering (SERS) spectroscopy, as a novel rapid detection technology, offers molecular fingerprinting capabilities that achieve trace-level detection. The key to optimizing SERS sensitivity and reliability lies in the precise control of the nanostructures of SERS substrates. Nature, through billions of years of evolution, has served as a masterful creator, developing organisms with remarkable abilities based on micro/nanostructures, such as the superhydrophobicity of lotus leaves and the strong adhesive forces of gecko feet. This review categorizes the recent developments in SERS substrates inspired by natural materials into three main types: plant-based, animal-based, and virus-based. Each category is explored in detail, describing how their unique nanoarchitectures inspire the development of highly sensitive SERS substrates, along with their fabrication methods and applications in analytical science. Additionally, the review identifies current challenges, such as the uniformity and scalability of naturally inspired SERS substrates and suggests future directions, including the integration of hybrid biomimetic structures and advanced manufacturing techniques. By fostering a deeper understanding of these nature-inspired materials, we aim to enhance the practical application of SERS in analytical science in the future.

The investigation of adhesion force of support membrane on the structure and performance of nanofiltration membrane

The surface properties of non-porous areas (>90 %) of support membranes were often overlooked to influence the performance of nanofiltration (NF) membranes. In this work, the role of the support membrane in interfacial polymerization (IP) during synthesis of NF membrane and consequently on its performance were quantitatively investigated from the perspective of adhesion force for the first time. The support membranes with considerable pore structures and different surface sulfonate (-SO3-) contents were prepared from different concentrations of polyethersulfone/sulfonated polysulfone (PES/SPSf) solutions. The adhesion forces of different support membranes were measured by atomic force microscope (AFM). The IP process between piperazine (PIP) and trimethylbenzoyl chloride (TMC) and the obtained polyamide (PA) layer on the support membranes were monitored by Quartz crystal microbalance with dissipation (QCM-D). The results indicated that the contents of sulfonic groups on the surface of the support membranes decreased as the casting-solution concentration increased (from 16 % to 28 %) due to a negative segregation phenomenon, which resulted in a decrease in the adhesion force (from 17.9 to 2.6 nN) between the support membranes and PIP monomers. The reduced adhesion force between the support membrane and PIP monomers led to an increase in the PA layer thickness (from 0.8 to 18 nm). Interestingly, the time to reach PA layer thickness equilibrium decreased (from 91 to 23 s). The obtained NF membranes (from PA@PES/SPSf16 to PA@PES/SPSf28) achieved the pure water permeance from 51.2 to 26.2 L m−2 h−1·bar−1 while the salt (Na2SO4) rejection from 97.5 to 99.5 %, respectively, was noted. It was demonstrated that controlling the adhesion force between the support membranes and PIP monomers could effectively regulate the structure and the performance of NF membranes. This work would provide valuable insights for designing high-performance NF membranes in practical applications.

Growth Behavior of Ni on Hydrogen-Etched WS2 Surface.

Transition metal dichalcogenides (TMDs) are 2D materials in which the layers are stacked together by van der Waals forces. Although TMDs are expected to be promising for electronic applications, forming a uniform electrode on them is challenging because of the low adhesion forces between metals and TMDs. This study focuses on improving the quality of metal electrodes by introducing atomic H to create surface defects, using Ni on WS2 as an example. The detailed effects of H etching and subsequent Ni growth were investigated using scanning tunneling microscopy (STM) and synchrotron-based X-ray photoemission (XPS) techniques. Our studies reveal that introducing point defects of ∼3.05 × 1011 cm-2 on the WS2 surface, results in a significant shift in Ni growth from the Volmer-Weber to a near Frank-van der Merwe mode. The origin of the change is the bond formation between the Ni and W atoms, which is expected to realize ohmic contact. The optimization of metal-TMD interfaces offers valuable insights for advanced applications.

Programmable adhesion through triangular and hierarchical cuts in metamaterial adhesives.

Metamaterial design approaches, which integrate structural elements into material systems, enable the control of uncommon behaviours by decoupling local and global properties. Leveraging this conceptual framework, metamaterial adhesives incorporate nonlinear cut architectures into adhesive films to achieve unique combinations of adhesion capacity, release, and spatial tunability by controlling how cracks propagate forward and in reverse directions during separation. Here, metamaterial adhesive designs are explored with triangular cut features while integrating hierarchical and secondary cut patterns among primary nonlinear cuts. Both cut geometry and secondary cut features tune adhesive force capacity and energy of separation. Importantly, the size and spacing of cut features must be designed around a critical length scale. When secondary cut features are greater than a critical length, cracks can be steered in multiple directions, going both forward and backwards within a primary attachment element. This control over crack dynamics enhances the work of separation by a factor of 1.5, while maintaining the peel force relative to a primary cut. If hierarchical cut features are too small or too compliant, they interact and do not distinctly modify crack behaviour. This work highlights the importance of adhesive length scales and stiffness for crack control and attachment characteristics in adhesive films.This article is part of the theme issue 'Origami/Kirigami-inspired structures: from fundamentals to applications'.

Mrlac1, an extracellular laccase, is required for conidial morphogenesis as well as the well adaptability in field of Metarhizium rileyi

Acting as an extremely promising fungal pesticide, Metarhizium rileyi exhibits robust insecticidal activity against Lepidoptera pests, particularly the larvae. Though there is a slight delay in efficacy, biopesticides offer salient advantages over traditional chemical pesticide especially in environmental safety, cyclic infection and resistant inhibition. In this study, an exterior T-DNA was randomly inserted into the genome of M. rileyi, resulting in the acquisition of a mutant strain that displayed a colour transition from green to yellow within its conidia. The disruption of Mrlac1, a laccase, has been confirmed to attribute to the epigenetic alterations. Mrlac1 is a secreted protein harboring an N-terminal signaling peptide that undergoes in vivo synthesis and accumulates on the cell wall of M. rileyi. Targeted knock-out mutant exhibited alterations not just in conidia coloration, but significantly diminished capacity to withstand external stressors, particularly non-biological factors such as high humidity, Congo red exposure, and UV radiation. The disruptant suffered a constraint on hyphal polar growth, alteration in conidial surface structure, as well as noticeable increase in adhesion forces between conidia, the core infection factors. There is a remarkable diminution in virulence of Mrlac1 deletion variant against larvae of Spodoptera litura by topical inoculation, but not hemolymph injection. Our findings suggest that Mrlac1 acts as a positive regulator in the normal morphogenesis of fungal conidia, encompassing pigment production, inter-conidia adhesion, and conidial cell wall integrity, while the preservation of these structures holds paramount importance for the survival and infection of M. rileyi in the field.

Peeling-induced interfacial roughness and charging for enhanced triboelectric power generation

To date, there have been a lot of efforts to enhance the conversion efficiency of triboelectric nanogenerators (TENGs) via physical and chemical modifications of the polymer surface. Herein, we report that a facile peeling of polymer from a substrate can enhance the triboelectric power output. The peeling of spin-coated polydimethylsiloxane (PDMS) from glass and polytetrafluoroethylene (PTFE) substrates has revealed a considerable increase in interfacial roughness and lateral friction. Surface-sensitive X-ray photoemission spectroscopy and non-contact current measurements have also revealed the transfer of counter-material and interfacial charging. The surface roughness of peeled PDMS is significant for the PTFE substrate, while the surface charge is significant for the glass substrate. The triboelectric output power density for peeled PDMS from the substrate is similar, 10.3 µW/cm2, but significantly larger than that for as-grown PDMS (2.2 µW/cm2). The peeling strength of PDMS significantly increases for glass compared to PTFE after the oxygen plasma treatment of substrates. The triboelectric charge of peeled PDMS from a plasma-treated glass substrate is almost 1.3 times larger than that from a PTFE substrate. This work implies that peeling polymer from a rough substrate with a large adhesion force would be a facile and effective way to increase the triboelectric power output, without any delicate surface treatments.

An experimental-cohesive zone model approach to predict fatigue life of adhesive joints with varying modes of loading and joint configurations for automotive applications

ABSTRACT Predictive fatigue life models of adhesive joints are necessary to enable the assessment of automotive-bonded structures while reducing costly experimental testing. However, contemporary models have typically been calibrated for specific joint configurations and modes of loading, limiting their applicability to large-scale structures. Additionally, available models are based on simulation of cumulative fatigue cycling, making them computationally prohibitive. In the current study, cross-tension (CT) (load angles of 0°, 45°, and 90°) and single-lap shear joint (SLJ) configurations were bonded using an epoxy adhesive (BetaGuard CI6125R; PPG, France) used in automotive production (one part) and tested under fatigue cyclic loading. A total of nine joint configurations, having symmetrical (same material and thickness) and asymmetrical (dissimilar material or unequal thickness) joints, were tested. Fatigue tests at load levels between 25% and 75% of the static peak load were performed until joint failure or to runout (two million load cycles). The static tests of the joints were simulated to failure using finite element (FE) models with the cohesive zone method (CZM). The maximum strain energy release rates ( G max ) were calculated within the adhesive bond line at static loads corresponding to the peak loads of the fatigue tests. The G max values, computed from single cycle, specimen-specific FE simulations, were correlated with the measured fatigue life ( N f ) of the adhesive joints with varying modes of loading and joint configurations. The fatigue life prediction model, based on G max − N f correlation and following a crack propagation approach, predicted the cycles to failure for 85% of the fatigue tests, and 81% of the independent validation tests. The proposed fatigue life prediction approach provides computational efficiency and large-scale compatibility.