Adenocarcinoma Of Sigmoid Colon Research Articles

Patterns of recurrence following curative resection alone for adenocarcinoma of the rectum and sigmoid colon.

Two-hundred-four patients with previously untreated adenocarcinoma of rectum, rectosigmoid, and sigmoid colon were retrospectively evaluated to determine patterns of recurrence following curative resection. Seventy-eight (38%) subsequently developed recurrent disease. Of these, 40% (31/78) presented with local recurrence alone, 28% (22/78) with regional recurrence, 15% (12/78) with concomitant local recurrence and distant metastasis, and 17% (13/78) with distant metastasis alone. The degree of tumor anaplasia and depth of tumor penetration into the bowel wall influenced the rate of local recurrence. Through five years local recurrence without clinical evidence of distant metastasis was the most common cause of death. Need for adjuvant radiation therapy is discussed.

Patterns of recurrence following resection for adenocarcinoma of rectum, rectosigmoid and sigmoid colon

Patterns of recurrence following resection for adenocarcinoma of rectum, rectosigmoid and sigmoid colon

Carcinoma of the Colon Occurring in an Inguinal Hernia

The presence of tumours within hernial sacs has been reported by a number of authors (Pagliani, 1937; Zimmerman, 1940; Oppenheimer, 1943). However, despite the frequency of carcinoma of the colon in surgical practice, its presence in a hernial sac is of extreme rarity. A review of the literature reveals only two reported instances. Gerhardt (1938) described the successful removal of a scirrhous adenocarcinoma of the upper sigmoid colon with an associated abscess in a left inguinal hernia, the diagnosis, in this instance, being determined at operation. Fieber and Wolstenholm (1955) recorded a further case of colonic tumour in a hernial sac, the patient being admitted with an obstructed left inguinal hernia. A radiograph of the abdomen revealed dilated loops of small and large bowel, the gas terminating in the sigmoid colon. A barium enema showed narrowing of the lumen of the sigmoid colon within the hernial sac. At operation the true nature of the hernial contents was disclosed. A mass of inflammatory tissue surrounded the incarcerated loop of sigmoid colon and, in the most dependent portion of the loop, a firm annular mass was felt. This was subsequently shown, histologically, to be an adenocarcinoma with invasion of the wall of the hernial sac. The authors wish to place on record a further example of this rare combination of tumour within a hernia. In this instance the diagnosis was suggested pre-operatively. B.P., aged 66 years, was admitted on 22.8.56 with symptoms suggestive of a carcinoma of the colon.