Additional Supervision Research Articles

Uncertainty‐guided symmetric multilevel supervision network for 3D left atrium segmentation in late gadolinium‐enhanced MRI

Atrial fibrillation (AF) is a common arrhythmia and requires volumetric imaging to guide the therapy procedure. Late gadolinium-enhanced magnetic resonance imaging (LGE MRI) is an efficient noninvasive technology for imaging the diseased heart. Three-dimensional segmentation of the left atrium (LA) in LGE MRI is a fundamental step for guiding the therapy of patients with AF. However, the low contrast and fuzzy surface of the LA in LGE MRI make accurate and objective LA segmentation a challenge. The purpose of this study is to propose an automatic and efficient LA segmentation model based on a convolutional neural network to obtain a more accurate predicted surface and improve the LA segmentationresults. In this study, we proposed an uncertainty-guided symmetric multilevel supervision (SML) network for 3D LA segmentation in LGE MRI. First, we constructed an SML structure to combine the corresponding features from the encoding and decoding stages to learn the multiscale representation of LA. Second, we formulated the discrepancy of predictions of our model as model uncertainty. Then we proposed an uncertainty-guided objective function to further increase the segmentation accuracy on thesurface. We evaluated our proposed model on the public LA segmentation database using four universal metrics. The proposed model achieved Hausdorff Distance (HD) of 11.68 mm, average symmetric surface distance of 0.92 mm, Dice score of 0.92, and Jaccard of 0.85. Compared with state-of-the-art models, our model achieved the best HD that is sensitive to surface accuracy. For the other three metrics, our model also achieved better or comparableperformance. We proposed an efficient automatic LA segmentation model that consisted of an SML structure and an uncertainty-guided objective function. Compared to other models, we designed an additional supervision branch in the encoding stage to learn more detailed representations of LA while learning global context information through the multilevel structure of each supervision branch. To address the fuzzy surface challenge of LA segmentation in LGE MRI, we leveraged the model uncertainty to enhance the distinguishing ability of the model on the surface, thereby the predicted accuracy of the LA surface can be further increased. We conducted extensive ablation and comparative experiments with state-of-the-art models. The experiment results demonstrated that our proposed model could handle the complex structure of LA and had superior advantages in improving the segmentation performance on thesurface.

Implementation of Group Interpersonal Psychotherapy in primary care.

ABSTRACTOBJECTIVE To show the implementation process of IPT-G in primary care, including facilitating and obstructing factors, implementation strategies, and training and supervision of primary care professionals.METHODS Quantitative (cross-sectional and longitudinal) analysis of pre and post-knowledge tests; qualitative analyses of the training courses; patient recruitment; conduction of IPT-G sessions; supervision of IPT-G therapists; application of a semi-structured questionnaire to assess, investigate, and develop strategies against the identified barriers.RESULTS About 120 clinicians answered the pre-test; 84 completed the post-test. Pre- and post-test scores of IPT-G knowledge were significantly different. Twenty initially trained clinicians completed additional supervision in IPT-G. Qualitative analysis identified twelve barriers and six facilitators to IPT-G implementation in individual, organizational, and systemic contexts.CONCLUSIONS Implementation of IPT-G in primary care is a complex process with several steps. In the first step, health professionals were successfully trained in IPT-G. However, subsequent steps were more complex. Therefore, careful planning of IPT-G implementation is essential to maximize the success of this innovation.

Behavioral Game Theory Model in Pollution Control with Additional Supervision

The work is devoted to the study of the impact of external control on the strategies of pollutant discharge enterprises and government regulators in the field of environmental protection. The authors construct a model of the relationship between these entities. It is an evolutionary game in which the players are entities that generate pollutants and the government departments that implement pollution supervision. The choice of strategies of both of these entities and the evolutionary stability of the system controlled by different regulatory efforts, i.e., a third party, are analyzed. The authors then verify the evolutionary paths and evolutionary results of the model under different conditions using simulation analysis based on this model. The conducted research shows that the weak power of third-party supervision is not enough to promote the evolution of the behavioral decisions of the government and enterprises. An appropriate increase in the power of third-party supervision will change the choice of the government and enterprises strategies in the short term; however, due to the mutual influence of the strategies between both sides of the game, in this situation, the evolutionary system does not pursue a stable state. The strong power of third-party supervision will push enterprises to choose a pollution control strategy, change the intensity of government supervision, and replace government supervision to a certain extent. It is an interesting example of modeling the relationship of this system on the basis of evolutionary game theory. The findings can be regarded as a theoretical reference for environmental pollution control of enterprises.

Measuring intrinsic human activity information using WiFi-based attention model

In this work, we have proposed the first WiFi-based attention model for intrinsic human activity information measuring. First, both convolutional layers and time-recurrent layers are integrated in a one-off manner for joint feature learning. Based on this, a temporal attention module is introduced to capture activity moments and reduce lengthy data collections. In addition, a channel-spatial attention module is further designed to retrieve the activity feature of interest, without requiring any additional supervision. Extensive experiments were conducted for performance comparison under diverse environmental settings. The results showed that our model can achieve the best overall accuracy of 94.62%, 94.36% and 91.04% in three datasets with minimal manual efforts involved, and consistently outperforms other baselines under diverse parameter settings.

CEKD:Cross ensemble knowledge distillation for augmented fine-grained data

Data augmentation has been proved effective in training deep models. Existing data augmentation methods tackle the fine-grained problem by blending image pairs and fusing corresponding labels according to the statistics of mixed pixels, which produces additional noise harmful to the performance of networks. Motivated by this, we present a simple yet effective cross ensemble knowledge distillation (CEKD) model for fine-grained feature learning. We innovatively propose a cross distillation module to provide additional supervision to alleviate the noise problem, and propose a collaborative ensemble module to overcome the target conflict problem. The proposed model can be trained in an end-to-end manner, and only requires image-level label supervision. Extensive experiments on widely used fine-grained benchmarks demonstrate the effectiveness of our proposed model. Specifically, with the backbone of ResNet-101, CEKD obtains the accuracy of 89.59%, 95.96% and 94.56% in three datasets respectively, outperforming state-of-the-art API-Net by 0.99%, 1.06% and 1.16%.

Integrating a community-based approach to non-communicable diseases care: a pilot programme in Bangladesh

BackgroundAs the threat of non-communicable diseases grows in Bangladesh, BRAC, in partnership with Medtronic, launched a pilot programme in early 2020 to leverage community health workers to improve the health outcomes of patients with hypertension and diabetes. This project builds off of BRAC's existing non-communicable disease programme, established in 2016, but incorporates patient-centred approaches to monitor and improve both patient compliance and outcomes. MethodsActivities included BRAC-run non-communicable disease centres to diagnose and treat patients with non-communicable diseases and specially trained community health workers to provide community-level care and strengthen referral linkages with NCD centres. BRAC also worked diligently to adapt its programming to the context of COVID-19, including equipping a subset of enrolled patients with machines to record their blood pressure and blood glucose levels at home with additional supervision by community health workers. FindingsPreliminary results were promising—on average, 90% of both home-based and clinic-based patients showed clinical improvements, and 91% were retained in care. About 98% of community health workers had on-time follow-up of patients with non-communicable diseases, showing routine compliance of care at the household level. InterpretationDespite the pandemic, community health workers proved to be an effective tool in chronic disease management because the community trusts them and is receptive to their guidance, empowering health workers to deliver non-communicable disease care and promote lifestyle modifications. Contingent on further funding, BRAC will evaluate the effectiveness of this model in sustaining clinical outcomes and identifying pathways to scale across BRAC's large-scale health programme of over 40 000 community health workers. FundingMedtronic (formerly known as Medtronic Foundation).

Unsupervised Learning of Monocular Depth and Ego-Motion with Optical Flow Features and Multiple Constraints.

This paper proposes a novel unsupervised learning framework for depth recovery and camera ego-motion estimation from monocular video. The framework exploits the optical flow (OF) property to jointly train the depth and the ego-motion models. Unlike the existing unsupervised methods, our method extracts the features from the optical flow rather than from the raw RGB images, thereby enhancing unsupervised learning. In addition, we exploit the forward-backward consistency check of the optical flow to generate a mask of the invalid region in the image, and accordingly, eliminate the outlier regions such as occlusion regions and moving objects for the learning. Furthermore, in addition to using view synthesis as a supervised signal, we impose additional loss functions, including optical flow consistency loss and depth consistency loss, as additional supervision signals on the valid image region to further enhance the training of the models. Substantial experiments on multiple benchmark datasets demonstrate that our method outperforms other unsupervised methods.

Out-of-Domain Discourse Dependency Parsing via Bootstrapping: An Empirical Analysis on Its Effectiveness and Limitation

Abstract Discourse parsing has been studied for decades. However, it still remains challenging to utilize discourse parsing for real-world applications because the parsing accuracy degrades significantly on out-of-domain text. In this paper, we report and discuss the effectiveness and limitations of bootstrapping methods for adapting modern BERT-based discourse dependency parsers to out-of-domain text without relying on additional human supervision. Specifically, we investigate self-training, co-training, tri-training, and asymmetric tri-training of graph-based and transition-based discourse dependency parsing models, as well as confidence measures and sample selection criteria in two adaptation scenarios: monologue adaptation between scientific disciplines and dialogue genre adaptation. We also release COVID-19 Discourse Dependency Treebank (COVID19-DTB), a new manually annotated resource for discourse dependency parsing of biomedical paper abstracts. The experimental results show that bootstrapping is significantly and consistently effective for unsupervised domain adaptation of discourse dependency parsing, but the low coverage of accurately predicted pseudo labels is a bottleneck for further improvement. We show that active learning can mitigate this limitation.

Human action recognition by multiple spatial clues network

Human action can be recognized in still images since the whole image represents an action with some spatial clues, such as human poses, action-specific parts, and global surroundings. To represent the spatial clues, the recent methods require labor-intensive annotations to locate the human body and objects, which are computationally intensive. To eliminate strong supervision, a Multiple Spatial Clues Network (MSCNet) is proposed to represent the spatial clues with only image-level action label. Neither accurately manual annotated bounding boxes nor extra labeled datasets are required as additional supervision. First, the proposed MSCNet exploits spatial-attention module to generate spatial attention regions, and detects the spatial clues with minimal supervision. Then, spatial clues exploitation is proposed to utilize the learned spatial clues with three modules: the context module, body + context module and body + semantics module. Experiments on three benchmark datasets demonstrate the effectiveness of the proposed MSCNet.

CrabNet for Explainable Deep Learning in Materials Science: Bridging the Gap Between Academia and Industry

Despite recent breakthroughs in deep learning for materials informatics, there exists a disparity between their popularity in academic research and their limited adoption in the industry. A significant contributor to this “interpretability-adoption gap” is the prevalence of black-box models and the lack of built-in methods for model interpretation. While established methods for evaluating model performance exist, an intuitive understanding of the modeling and decision-making processes in models is nonetheless desired in many cases. In this work, we demonstrate several ways of incorporating model interpretability to the structure-agnostic Compositionally Restricted Attention-Based network, CrabNet. We show that CrabNet learns meaningful, material property-specific element representations based solely on the data with no additional supervision. These element representations can then be used to explore element identity, similarity, behavior, and interactions within different chemical environments. Chemical compounds can also be uniquely represented and examined to reveal clear structures and trends within the chemical space. Additionally, visualizations of the attention mechanism can be used in conjunction to further understand the modeling process, identify potential modeling or dataset errors, and hint at further chemical insights leading to a better understanding of the phenomena governing material properties. We feel confident that the interpretability methods introduced in this work for CrabNet will be of keen interest to materials informatics researchers as well as industrial practitioners alike.

Beyond state scope of practice laws for advanced practitioners: Additional supervision requirements for buprenorphine prescribing

BackgroundBuprenorphine is a life-saving medication for people with opioid use disorder (OUD). U.S. federal law allows advanced practice clinicians (APCs), such as nurse practitioners (NPs) and physician assistants (PAs), to obtain a federal waiver to prescribe buprenorphine in office-based practices. However, states regulate APCs' scope of practice (SOP) variously, including requirements for physician supervision. States may also have laws entirely banning NP/PA buprenorphine prescribing or requiring that supervising physicians have a federal waiver to prescribe buprenorphine. We sought to identify prevalence of state laws other than SOP laws that either 1) prohibit NP/PA buprenorphine prescribing entirely, or 2) require supervision by a federally waivered physician. MethodsWe searched for state statutes and regulations in all 50 states and Washington D.C. regulating prescribing of buprenorphine for OUD by APCs during summer 2021. We excluded general scope of practice laws, laws only applicable to Medicaid-funded clinicians, laws not applicable to substance use disorder (SUD) treatment, and laws only applicable to NPs/PAs serving licensed SUD treatment facilities. We then conducted content analysis. ResultsOne state prohibits all APCs from prescribing buprenorphine for OUD, even though the state's general SOP laws permit APC buprenorphine prescribing. Five states require PA supervision by a federally waivered physician. Three states require NP supervision by a federally waivered physician. ConclusionsAside from general scope of practice laws, several states have created laws explicitly regulating buprenorphine prescribing by APCs outside of licensed state SUD facilities.

Rolling Shutter Inversion: Bring Rolling Shutter Images to High Framerate Global Shutter Video.

A single rolling-shutter (RS) image may be viewed as a row-wise combination of a sequence of global-shutter (GS) images captured by a (virtual) moving GS camera within the exposure duration. Although rolling-shutter cameras are widely used, the RS effect causes obvious image distortion especially in the presence of fast camera motion, hindering downstream computer vision tasks. In this paper, we propose to invert the rolling-shutter image capture mechanism, i.e., recovering a continuous high framerate global-shutter video from two time-consecutive RS frames. We call this task the RS temporal super-resolution (RSSR) problem. The RSSR is a very challenging task, and to our knowledge, no practical solution exists to date. This paper presents a novel deep-learning based solution. By leveraging the multi-view geometry relationship of the RS imaging process, our learning based framework successfully achieves high framerate GS generation. Specifically, three novel contributions can be identified: (i) novel formulations for bidirectional RS undistortion flows under constant velocity as well as constant acceleration motion model. (ii) a simple linear scaling operation, which bridges the RS undistortion flow and regular optical flow. (iii) a new mutual conversion scheme between varying RS undistortion flows that correspond to different scanlines. Our method also exploits the underlying spatial-temporal geometric relationships within a deep learning framework, where no additional supervision is required beyond the necessary middle-scanline GS image. Building upon these contributions, this paper represents the very first rolling-shutter temporal super-resolution deep-network that is able to recover high framerate global-shutter videos from just two RS frames. Extensive experimental results on both synthetic and real data show that our proposed method can produce high-quality GS image sequences with rich details, outperforming the state-of-the-art methods.

Video Pivoting Unsupervised Multi-Modal Machine Translation.

The main challenge in the field of unsupervised machine translation (UMT) is to associate source-target sentences in the latent space. As people who speak different languages share biologically similar visual systems, various unsupervised multi-modal machine translation (UMMT) models have been proposed to improve the performances of UMT by employing visual contents in natural images to facilitate alignment. Commonly, relation information is the important semantic in a sentence. Compared with images, videos can better present the interactions between objects and the ways in which an object transforms over time. However, current state-of-the-art methods only explore scene-level or object-level information from images without explicitly modeling objects relation; thus, they are sensitive to spurious correlations, which poses a new challenge for UMMT models. In this paper, we employ a spatial-temporal graph obtained from videos to exploit object interactions in space and time for disambiguation purposes and to promote latent space alignment in UMMT. Our model employs multi-modal back-translation and features pseudo-visual pivoting, in which we learn a shared multilingual visual-semantic embedding space and incorporate visually pivoted captioning as additional weak supervision. Experimental results on the VATEX Translation 2020 and HowToWorld datasets validate the translation capabilities of our model on both sentence-level and word-level and generalizes well when videos are not available during the testing phase.

Brain Lesion Synthesis via Progressive Adversarial Variational Auto-Encoder.

Laser interstitial thermal therapy (LITT) is a novel minimally invasive treatment that is used to ablate intracranial structures to treat mesial temporal lobe epilepsy (MTLE). Region of interest (ROI) segmentation before and after LITT would enable automated lesion quantification to objectively assess treatment efficacy. Deep learning techniques, such as convolutional neural networks (CNNs) are state-of-the-art solutions for ROI segmentation, but require large amounts of annotated data during the training. However, collecting large datasets from emerging treatments such as LITT is impractical. In this paper, we propose a progressive brain lesion synthesis framework (PAVAE) to expand both the quantity and diversity of the training dataset. Concretely, our framework consists of two sequential networks: a mask synthesis network and a mask-guided lesion synthesis network. To better employ extrinsic information to provide additional supervision during network training, we design a condition embedding block (CEB) and a mask embedding block (MEB) to encode inherent conditions of masks to the feature space. Finally, a segmentation network is trained using raw and synthetic lesion images to evaluate the effectiveness of the proposed framework. Experimental results show that our method can achieve realistic synthetic results and boost the performance of down-stream segmentation tasks above traditional data augmentation techniques.

Distillation Remote Sensing Object Counting via Multi-Scale Context Feature Aggregation

Remote sensing object counting is an important issue in remote sensing analysis. Remote sensing object counting has many challenges, such as large-scale variations and complex backgrounds. The previous counting methods have many shortboards, such as only focusing on local appearance features of target scenes and ignoring the self-supervision ability of the network itself. To remedy the above problems, in this article, we propose a novel remote sensing object counting method, which contains the adaptive multi-scale context aggregation module (AMCAM) and the self-context distillation module (SCDM). The AMCAM can model and fuse context information from different receptive fields effectively. It also keeps detailed information through multiple pixel attention (PA) modules step by step. The SCDM can improve the representation learning without adding any additional supervision information. SCDM uses feature maps from the deeper layer of the network to supervise feature maps from the earlier layer of the network. Our method has achieved good performance on the remote sensing object counting dataset, RSOC, and mainstream crowd counting datasets, such as ShanghaiTech and UCF-QNRF datasets.

Image Super-Resolution Reconstruction Based on Dual Residual Network

Research shows that deep learning algorithms can effectively improve a single image's super-resolution quality. However, if the algorithm is solely focused on increasing network depth and the desired result is not achieved, difficulties in the training process are more likely to arise. Simultaneously, the function space that can be transferred from a low-resolution image to a high-resolution image is enormous, making finding a satisfactory solution difficult. In this paper, we propose a deep learning method for single image super-resolution. The MDRN network framework uses multi-scale residual blocks and dual learning to fully acquire features in low-resolution images. Finally, these features will be sent to the image reconstruction module to restore high-quality images. The function space is constrained by the closed-loop formed by dual learning, which provides additional supervision for the super-resolution reconstruction of the image. The up-sampling process includes residual blocks with short-hop connections, so that the network focuses on learning high-frequency information, and strives to reconstruct images with richer feature details. The experimental results of ×4 and ×8 super-resolution reconstruction of the image show that the quality of the reconstructed image with this method is better than some existing experimental results of image super-resolution reconstruction in subjective visual effects and objective evaluation indicators.

Deformable convolutions in multi-view stereo

The Multi-View Stereo (MVS) is a key process in the photogrammetry workflow. It is responsible for taking the camera's views and finding the maximum number of matches between the images yielding a dense point cloud of the observed scene. Since this process is based on the matching between images it greatly depends on the ability of features matching throughout different images. To improve the matching performance several researchers have proposed the use of Convolutional Neural Networks (CNNs) to solve the MVS problem. Despite the progress in the MVS problem with the usage of CNNs, the Video RAM (VRAM) consumption within these approaches is usually far greater than classical methods, that rely more on RAM, which is cheaper to expand than VRAM. This work then follows the progress made in CasMVSNet in the reduction of GPU memory usage, and further study the changes in the feature extraction process. The Average Group-wise Correlation is used in the cost volume generation, to reduce the number of channels in the cost volume, yielding a reduction in GPU memory usage without noticeable penalties in the result. The deformable convolutions are applied in the feature extraction network to augment the spatial sampling locations with learning offsets, without additional supervision, to further improve the network's ability to model transformations. The impact of these changes is measured using quantitative and qualitative tests using the DTU and the Tanks and Temples datasets. The modifications reduced the GPU memory usage by 32% and improved the completeness by 9% with a penalty of 6.6% in accuracy on the DTU dataset.

Changes Made to Orders Placed by Overnight Admitting Residents on Teaching Rounds the Next Day.

Increased focus on health care quality and safety has generally led to additional resident supervision by attending physicians. At our children's hospital, residents place orders overnight that are not explicitly reviewed by attending physicians until morning rounds. We aimed to categorize the types of orders that are added or discontinued on morning rounds the morning after admission to a resident team and to understand the rationale for these order additions and discontinuations. We used our hospital's data warehouse to generate a report of orders placed by residents overnight that were discontinued the next morning and orders that were added on rounds the morning after admission to a resident team from July 1, 2017 to June 29, 2018. Retrospective chart review was performed on included orders to determine the reason for order changes. Our report identified 5927 orders; 538 were included for analysis after exclusion of duplicate orders, administrative orders, and orders for patients admitted to non-Pediatric Hospital Medicine services. The reason for order discontinuation or addition was medical decision-making (n = 357, 66.4%), change in patient trajectory (n = 151, 28.1%), and medical error (n = 30, 5.6%). Medical errors were most commonly related to medications (n = 24, 80%) and errors of omission (n = 19, 63%). New or discontinued orders commonly resulted from evolving patient management decisions or changes in patient trajectory; medical errors represented a small subset of identified orders. Medical errors were often errors of omission, suggesting an area to direct future safety initiatives.

A feasibility study to assess non-clinical community health workers\u2019 capacity to use simplified protocols and tools to treat severe acute malnutrition in Niger state Nigeria

BackgroundSevere acute malnutrition (SAM) is a major determinant of childhood mortality and morbidity. Although integrated community case management (iCCM) of childhood illnesses is a strategy for increasing access to life-saving treatment, malnutrition is not properly addressed in the guidelines. This study aimed to determine whether non-clinical Community Health Workers (called Community-Oriented Resource Persons, CORPs) implementing iCCM could use simplified tools to treat uncomplicated SAM.MethodsThe study used a sequential multi-method design and was conducted between July 2017 and May 2018. Sixty CORPs already providing iCCM services were trained and deployed in their communities with the target of enrolling 290 SAM cases. Competency of CORPs to treat and the treatment outcomes of enrolled children were documented. SAM cases with MUAC of 9 cm to < 11.5 cm without medical complications were treated for up to 12 weeks. Full recovery was at MUAC≥12.5 cm for two consecutive weeks. Supervision and quantitative data capturing were done weekly while qualitative data were collected after the intervention.ResultsCORPs scored 93.1% on first assessment and increment of 0.11 (95% CI, 0.05–0.18) points per additional supervision conducted. The cure rate from SAM to full recovery, excluding referrals from the denominator in line with the standard for reporting SAM recovery rates, was 73.5% and the median length of treatment was 7 weeks. SAM cases enrolled at 9 cm to < 10.25 cm MUAC had 31% less likelihood of recovery compared to those enrolled at 10.25 cm to < 11.5 cm. CORPs were not burdened by the integration of SAM into iCCM and felt motivated by children’s recovery. Operational challenges like bad terrains for supervision, supply chain management and referrals were reported by supervisors, while Government funding was identified as key for sustainability.ConclusionThe study demonstrated that with training and supportive supervision, CORPs in Nigeria can treat SAM among under-fives, and refer complicated cases using simplified protocols as part of an iCCM programme. This approach seemed acceptable to all stakeholders, however, the effect of the extra workload of integrating SAM into iCCM on the quality of care provided by the CORPs should be assessed further.

Data-Efficient Sensor Upgrade Path Using Knowledge Distillation.

Deep neural networks have achieved state-of-the-art performance in image classification. Due to this success, deep learning is now also being applied to other data modalities such as multispectral images, lidar and radar data. However, successfully training a deep neural network requires a large reddataset. Therefore, transitioning to a new sensor modality (e.g., from regular camera images to multispectral camera images) might result in a drop in performance, due to the limited availability of data in the new modality. This might hinder the adoption rate and time to market for new sensor technologies. In this paper, we present an approach to leverage the knowledge of a teacher network, that was trained using the original data modality, to improve the performance of a student network on a new data modality: a technique known in literature as knowledge distillation. By applying knowledge distillation to the problem of sensor transition, we can greatly speed up this process. We validate this approach using a multimodal version of the MNIST dataset. Especially when little data is available in the new modality (i.e., 10 images), training with additional teacher supervision results in increased performance, with the student network scoring a test set accuracy of 0.77, compared to an accuracy of 0.37 for the baseline. We also explore two extensions to the default method of knowledge distillation, which we evaluate on a multimodal version of the CIFAR-10 dataset: an annealing scheme for the hyperparameter and selective knowledge distillation. Of these two, the first yields the best results. Choosing the optimal annealing scheme results in an increase in test set accuracy of 6%. Finally, we apply our method to the real-world use case of skin lesion classification.