This study introduces a lead-free alternative for enhanced radiation protection. While lead aprons effectively attenuate ionizing radiation, concerns regarding flexibility, weight, and environmental hazards persist. In response, the present research is focused on producing an innovative sheet shielding comprised of carefully selected dense metal oxide microparticles (DMOs-MPs) and liquid silicone rubber (LSR). To evaluate the efficacy of the LSR samples, the current study uses rigorous testing procedures, such as microstructure characterization using EDX and FESEM. Furthermore, the study investigated key attenuation parameters within the LSR samples. Radiation protection was greatly and effectively supplied using DMOs-MPs filler (Bi-1 to Bi-7) in LSR samples; this protection reached 99.9% in the X-ray energy range. Due to the unique characteristics of the Bi-7, the results demonstrated that the samples’ shielding efficiency improved with the addition of high atomic number and high-density fillers. It had the greatest attenuation coefficient and density. At 60 keV, Bi-7’s density was 2.980 gcm−3, and its LAC and MAC were 19.2621 cm−1 and 6.4638 cm2/g, respectively. It also had the lowest half-value layer values in the energy range of 60–120 keV. The LSR samples showed effective radiation absorption for different energy levels, indicating that LSR can enhance the flexibility and comfort of the apron while providing adequate radiation protection. The incorporation of the DMOs-MPs with LSR represents an effective contribution and a noteworthy stride to enhance the safety and well-being of medical professionals routinely exposed to ionizing radiation.