In this paper, a fixed-time tracking control problem for an unmanned underwater vehicle (UUV) is investigated in the case of strong external sudden disturbances, model uncertainty, time-varying disturbances and specified performance constraints. First, a modified barrier Lyapunov function (QABLF) is proposed to increase applicability by introducing the standard quadratic Lyapunov function (QLF) and the logarithmic asymmetric barrier Lyapunov function (ABLF). The QALBF has two types and can be constructed to avoid violations of full and partial state constraints by parameter modification. Second, adaptive antisaturation appointed-time prescribed performance functions (APPFs) are introduced in the QABLF for the first time to relax the overshoot restriction and reduce the effect of input saturation on the performance constraint. Third, based on the backstepping method, a robust H∞ control strategy is developed to address strong, sudden disturbances. An auxiliary variable is designed to compensate for input saturation. Next, an improved adaptive radial basis function neural network (ARBFNN) is proposed to match the time-varying disturbances and model uncertainty. Finally, composite robust fixed-time control is achieved with high robustness and transient performance, which guarantees that the closed-loop system is fixed-time convergent. Moreover, the feasibility of the proposed controller is verified by Lyapunov analysis and numerical simulation.