This paper proposes an adaptive neural trajectory tracking control scheme for n-DOF robotic manipulators subjected to parameter variations, unknown functions, and time-varying external disturbances. First, the computed torque control (CTC) method is designed to reduce the system's nonlinearity. Second, radial basis function neural networks (RBFNNs) are constructed to approximate the uncertainties due to parameter variations and unknown functions. It's also important to note that the RBFNN's centers and widths are defined by state constraints. As a result of the nonlinear disturbance observer (NDO), the RBFNNs' approximation errors and disturbances are estimated to further improve tracking performance. The barrier Lyapunov function (BLF) ensures the closed-loop system's stability, guaranteeing tracking performance while preventing state constraint violation. Furthermore, sensitivity analysis provides a ranking of the importance of design parameters in influencing dynamic responses. Finally, simulations on a 7-DOF robotic manipulator are performed to validate the effectiveness of the proposed method.