Automated vehicles (AVs) are deemed to be the key element for the intelligent transportation system in the future. Many studies have been made to improve AVs’ ability of environment recognition and vehicle control, while the attention paid to decision making is not enough and the existing decision algorithms are very preliminary. Therefore, a framework of the decision-making training and learning is put forward in this paper. It consists of two parts: the deep reinforcement learning (DRL) training program and the high-fidelity virtual simulation environment. Then the basic microscopic behavior, car-following (CF), is trained within this framework. In addition, theoretical analysis and experiments were conducted to evaluate the proposed reward functions for accelerating training using DRL. The results show that on the premise of driving comfort, the efficiency of the trained AV increases 7.9% and 3.8% respectively compared to the classical adaptive cruise control models, intelligent driver model and constant-time headway policy. Moreover, on a more complex three-lane section, we trained an integrated model combining both CF and lane-changing behavior, with the average speed further growing 2.4%. It indicates that our framework is effective for AV’s decision-making learning.