A major water governance concern is how to coordinate the complex relationships of the water, food, and energy sectors and the resulting economic, social, and environmental consequences. Focusing on the challenges in one sector (e.g. water shortage in the water sector) and making decisions without considering other sectors will not solve these problems; rather, it will create a new problem (the decline of food production) in the food sectors. The nexus approach is a novel method to represent the interrelated challenges of the water, food, and energy sectors by considering the sectors’ policies to achieve sustainable development. The present study analyzes the social network of nexus actors in the Yazd-Ardakan aquifer, Yazd province, Iran. For this purpose, 54 partners in the nexus network were first identified in various public, private, semi-private and non-governmental organizations. Three types of interactions (knowledge and information exchange, budget transfer, and collaboration) were analyzed among the actors. The actor-network was, then, assessed at the levels of the entire network and individual actors. Then, a coherence analysis was performed by the density index at the entire network level, and the power analysis was carried out using in-degree, out-degree, betweenness, closeness, and eigenvector centrality indices at the individual actor level. Social network analysis criteria were, then, incorporated with the multi-criteria decision-making model ELECTRE I to select the key and powerful actors in the nexus network. Next, the powerful actors were identified and introduced with respect to 15 criteria employed in the social network analysis. According to the results, the power structure in the nexus network of the research area is not at equilibrium. Most of the power lies with the public sector. The water, food, and energy sectors act alone and they do not exploit their maximum organizational capacities to establish relationships with one another.