Activity Energy Expenditure Research Articles

Assessing the post-release effects of capture, handling and placement of satellite telemetry devices on narwhal (Monodon monoceros) movement behaviour.

Animal-borne telemetry devices have become a popular and valuable means for studying the cryptic lives of cetaceans. Evaluating the effect of capture, handling and tagging procedures remains largely unassessed across species. Here, we examine the effect of capture, handling and tagging activities on an iconic Arctic cetacean, the narwhal (Monodon monoceros), which has previously been shown to exhibit an extreme response to extended capture and handling. Using accelerometry-derived metrics of behaviour, including activity level, energy expenditure and swimming activity, we quantify the post-release responses and time to recovery of 19 individuals following capture and tagging activities considering the intrinsic covariates of sex and individual size and the extrinsic covariates of handling time and presence of a 'bolt-on' satellite telemetry device. From accelerometer-derived behaviour, most narwhals appeared to return to mean baseline behaviour (recovery) within 24hours after release, which was supported by longer-term measures of diving data. None of the covariates measured, however, had an effect on the time individuals took to recover following release. Using generalized additive models to describe changes in behaviour over time, we found handling time to be a significant predictor of activity levels, energy expenditure and swimming behaviour following release. Individuals held for the longest period (>40min) were found to display the largest effect in behaviour immediately following release with respect to swimming behaviour and activity levels. We also found some support for relationships between activity levels, energy expenditure and swimming activity and two other covariates: sex and the attachment of a bolt-on configuration satellite tags. Our results indicate that narwhals recover relatively quickly following capture, handling and tagging procedures, but we suggest that researchers should minimize handling time and further investigation is needed on how to mitigate potential effects of bolt-on satellite tags in these sensitive species.

Reliability and validity of the Glittre-ADL test to assess the functional status of patients with interstitial lung disease.

The study objective was to investigated the reliability and validity of the ADL-Glittre test (TGlittre) to assess the functional status of patients with interstitial lung disease (ILD). Twenty-one individuals with ILD participated (age: 63 ± 11 years; DLCO: 51.0 ± 12.6%predicted), evaluated with body plethysmography, Saint George Respiratory Questionnaire, modified Medical Research Council dyspnea scale, six-minute walk test (6MWT) and monitoring of physical activity of daily living. Two TGlittre were performed, with an interval of 30 minutes between them. The TGlittre demonstrated high test-retest reliability, with an intraclass correlation coefficient of 0.90 (95%CI: 0.75–0.96; p < 0.001). Nineteen patients (90.5%) performed better on the second test (mean difference between TGlittre 1 and 2: −0.57 ± 0.96 minute; p = 0.001), with a learning effect of 11.6%. The time in TGlittre correlated with 6MWT (r = −0.70; p = 0.002) and with the total energy expenditure in physical activity of daily living (r = −0.52; p = 0.02). In %predicted, TGlittre and 6MWT also correlated (r = −0.50; p = 0.04). Correlations were observed between TGlittre and pulmonary function variables (r = −0.47 to −0.57; p = 0.01 to p = 0.04). There was no difference in the physiological response between TGlittre 1 and 2, and between TGlittre and 6MWT (p > 0.05). In conclusion, the TGlittre is reliable and valid for assessing functional status of patients with ILD.

Can We Use Consumer-Wearable Activity Tracker Fitbit in Parkinson Disease?

Consumer-wearable activity trackers have been used for monitoring health-related metrics to estimate steps, distance, physical activity, energy expenditure, and sleep. The purpose of this mini review was to summarize the evidence for validity of the most popular wrist-worn activity tracker (Fitbit) to estimate those health-related metrics in Parkinson disease. We researched full-length English studies in PubMed, Science Direct, Google Scholar, and Scopus, through September, 2021. In total, 27 studies and a textbook description were included in the review. To adapt consumer-wearable activity trackers for evaluating health-related metrics in Parkinson’s disease (PD) patients, there may be some points to be elucidated and conquered. First, measurement accuracy and precision are required. Second, inter-device reliability for measuring steps, distance, and energy expenditure must be considered. Third, wearability: there are some types of device such as wrist-worn, ankle-worn, belt-fixed, and so on. Overall, Fitbit has advantage for these points. This mini review indicates that Fitbit has enough measurement accuracy and precision to estimate health-related metrics of PD patients including amount of step, physical activity energy expenditure, and quality of sleep.

The development and initial validation of the Health and Reproductive Survey (HeRS).

Background:Due to the diversity in profiles associated with the female reproductive cycle and their potential physiological and psychological effects, monitoring the reproductive status of exercising females is important from a practical and research perspective. Moreover, as physical activity can influence menstrual function, the effects of physical activity energy expenditure on reproductive function should also be considered.Aim:The aim of this study was to develop and establish initial face and content validity of the Health and Reproductive Survey (HeRS) for physically active females, which is a retrospective assessment of menstrual function from menarche (first menstruation) to menopause (cessation of menstruation).Methods:Face validity was evaluated qualitatively, and the initial content validity was established through a principal component analysis. The face validity process was completed by 26 females aged 19–67 years and the content validity was established through a survey sent to a convenience sample of 392 females, of which 230 females (57.9% and aged 18–49 years) completed the survey.Results:The revisions made following the face validation improved the understanding, flow, and coherence of the survey. The principal component analysis indicated that, at a minimum, the survey measures these constructs: menstrual cessation and associated moderators, athletic participation and performance levels (as associated with menstruation change and the menstrual cycle), age and menstrual cessation, hormonal contraception (“birth control”), and menarche and associated moderators.Conclusion:The Health and Reproductive Survey (HeRS) is a partially validated tool that can be used by researchers to characterize the menstrual status of physically active females relative to their physical activity status.

The Relevance of Revising Food Supply Norms for Students of Cadet-Type Boarding Schools

Summary. Introduction: At present, training of highly qualified military personnel including cadet corps students acquires special importance. Educational programs in cadet corps provide for high daily physical activity of students. At the same time, daily food rationing regulated by current sanitary norms and rules does not comply with higher energy expenditures of such students. The purpose of our study was to substantiate a healthy diet of students of boarding schools taking into account their total daily energy expenditures, calorie needs and requirements for micro- and macronutrients ensuring a high level of functional state of the body, high mental and physical performance. Materials and methods: We studied indicators of health status and physical development of cadets based on the results of medical examinations, results of assessing daily physical activity, and school meals. Daily timekeeping and pulse measurements were used to estimate daily energy expenditures and activity levels. Evaluation of nutrition was based on the analysis of a cyclic menu, process charts, menu layouts, and catering hours. Conclusions: The regulated daily norms of food products adopted in cadet corps subordinate to the Ministry of Education of the Russian Federation are significantly lower than actual energy expenditures of their students. This reality determines the necessity of revising food rationing. Draft guidelines for hygienic justification of the recommended diet for students with a higher level of physical activity have been developed. The proposals for improvement of boarding school meals were included in the appropriate sanitary rules and regulations within the framework of the regulatory guillotine.

Prevalence of Low Energy Availability in Collegiate Women Soccer Athletes.

(1) Background: Limited information exists on the prevalence of low energy availability (LEA) in collegiate team sports. The purpose of this study was to examine the prevalence of LEA in collegiate women soccer players. (2) Methods: Collegiate women soccer athletes (n = 18, height: 1.67 ± 0.05 m; body mass: 65.3 ± 7.9 kg; body fat %: 24.9 ± 5.6%) had their body composition and sport nutrition knowledge assessed in the pre-season. Energy availability was assessed mid-season using a 4-day dietary log and activity energy expenditure values from a team-based monitoring system. A validated screening tool was used to screen for LEA. (3) Results: The screening tool classified 56.3% of athletes as at risk of LEA (<30 kcal/kg of FFM); however, the actual dietary intake identified 67% as LEA. Athletes identified as non-LEA consumed significantly more absolute (p = 0.040) and relative (p = 0.004) energy than LEA athletes. (4) Conclusions: There was a high prevalence of LEA among collegiate women soccer athletes. Although previously validated in women endurance athletes, the LEA screening tool was not effective in identifying those at risk of LEA in this sample of athletes.

The Association Between Self-Reported and Objectively Measured Energy Level in Older Adults

Energy is an important concept in human health and diseases. Self-reported energy has been described as “the individual’s potential to perform physical and mental activity” and “the individual’s energy availability”. However, little empirical data exists on whether self-reported energy level is related to objectively measured energy level. Prior research suggests that more energy availability is associated with higher physical activity level. It remains unclear whether self-reported energy availability would be associated with objectively measured energy level, such as active energy expenditure and total energy expenditure. Using data from the Health, Aging and Body Composition Study, we identified 94 participants (mean age=86.2±2.4 y/o, 46%blacks, 52%women) with concurrent data on self-reported energy (scale 0-10) and objective energy level by the SenseWear Armband. We examined cross-sectional associations of self-reported energy with objectively measured energy and physical activity levels using Spearman correlation. Greater self-reported energy level was associated with higher daily active energy expenditure in kcal (r=0.30,p=0.004), higher METs (r=0.33,p<0.001), more minutes of physical activity (r=0.35,p<0.001), and more step counts (r=0.36,p<0.001). Self-reported energy was not associated with total energy expenditure (p=0.87) or estimated resting metabolic rate (p=0.53). Self-reported energy may reflect an individual’s activity energy expenditure but not total energy expenditure. It further supports the hypothesis that energy availability even by self-report connects to physical activity behavior. Whether self-reported energy correlates with other health outcomes warrants further investigation.

Influence of Physical Activity Energy Expenditure on Functional Fitness Among Older Adults

Remaining physically active as one ages plays a critical role in maintaining health and improving functional capacity. Further, older adults can see additional health-related benefits by increasing intensity, duration, frequency, and/or levels of physical activity. However, there is limited research examining physical activity energy expenditure (PAEE) and measures of functional fitness. Therefore, the purpose was to examine differences between older adults with varying levels of PAEE on selected measures of functional fitness. A sample of 25 adults (age: 74.0±7.1 years) were recruited from an urban area and divided into two groups. PAEE was calculated using the total caloric expenditure per week for all exercise-related activities from a self-reported PA questionnaire. Group one expended less than 3,000 calories per week and group two spent more than 3,000 calories per week performing PA. The selected measures of functional fitness were a 4-m gait speed (GS), 30-s chair stand test (CS-30), 2-min step test (ST), and the 8-foot up and go test (GUG). Data were analyzed using a one-way ANOVA. There was a statistically significant difference between the groups on GS (F1, 24 = 9.29, p < .01) and CS-30 (F1, 24 = 4.37, p = .05). The results yielded a trend for the GUG (p =.06). However, there was not a difference between the groups on the ST (p = .11). These results suggest older adults expending more than 3,000 calories per week performing PA walk faster and have greater lower-body strength.

Test-retest reliability and concurrent validity of the Adapted Short QUestionnaire to ASsess Health-enhancing physical activity (Adapted-SQUASH) in adults with disabilities

ABSTRACT The current study determined the test–retest reliability and concurrent validity of the Adapted Short QUestionnaire to ASsess Health-enhancing physical activity (Adapted-SQUASH) in adults with disabilities. Before filling in the Adapted-SQUASH twice with a recall period of 2 weeks, participants wore the Actiheart activity monitor up to 1 week. For the test–retest reliability (N = 68), Intraclass correlation coefficients (ICCs) were 0.67 (p < 0.001) for the total activity score (min x intensity/week) and 0.76 (p < 0.001) for the total minutes of activity (min/week). For the concurrent validity (N = 58), the Spearman correlation coefficient was 0.40 (p = 0.002) between the total activity score of the first administration of the Adapted-SQUASH and activity energy expenditure from the Actiheart (kcals kg−1 min−1). The ICC was 0.22 (p = 0.027) between the total minutes of activity assessed with the first administration of the Adapted-SQUASH and Actiheart. The Adapted-SQUASH is an acceptable measure to assess self-reported physical activity in large populations of adults with disabilities but is not applicable at the individual level due to wide limits of agreement. Self-reported physical activity assessed with the Adapted-SQUASH does not accurately represent physical activity assessed with the Actiheart in adults with disabilities, as indicated with a systematic bias between both instruments in the Bland–Altman analysis.

Effects of fatigue and kinesiophobia on functional capacity, physical activity and quality of life in Parkinson's disease.

The aim of this study was to investigate the effects of fatigue and fatigue-related kinesiophobia on functional capacity, physical activity and quality of life in patients with Parkinson's disease. Twenty patients with Parkinson's disease were included in the study. The fatigue severity was assessed by the Fatigue Severity Scale, kinesiophobia by the Tampa Kinesiophobia Scale, functional capacity with the Six-Minute Walk Test, and quality of life was evaluated by the Parkinson's Disease Questionnaire. In addition, the physical activity level of each patient, such as the number of steps, active energy expenditure and total energy expenditure, were recorded for one week with an activity monitor mounted on the patients' arms. The mean age of the patients (10 female/10 male) was 69.85 ± 9.38. According to the multiple regression analysis, a significant correlation was found between fatigue with 6-min walking test score (P = 0.039) and number of steps (P = 0.030). Also, a significant correlation was found between kinesiophobia with total energy expenditure (P = 0.013) and quality of life (P = 0.042). While fatigue was a significant determinant for functional capacity and number of steps, kinesiophobia was a significant determinant for total energy expenditure and quality of life. Fatigue and kinesiophobia are emphasized less compared to other findings in Parkinson's disease. However, fatigue and kinesiophobia symptoms negatively affect the functional capacity, physical activity and quality of life of patients. The results of this study revealed the need to evaluate fatigue and kinesiophobia, and the need to use physiotherapy and rehabilitation interventions to reduce these symptoms.

Acute Changes in Energy Expenditure and Heart Rate Variability During and Right After One Hour of Hatha Yoga Practice

Abstract Introduction. This study purposed to examine energy expenditure (EE) of one-hour hatha yoga (HY) practice and to compare changes in heart rate variability (HRV) during and right after HY practice. Material and methods. A total of ten experienced female HY practitioners participated in the study voluntarily. Daily EE on a weekday and during a one-hour HY session was measured using a metabolic holter. The ECG holter was applied to record HRV variables 5 minutes before, during, 5 minutes after and 10 minutes after the one-hour HY session. The HY session included HY asanas for the first 55 minutes and meditation during the last 5 minutes. Results. Participants showed 2201.40 kcal of total EE, and 421.70 kcal of active EE during the weekday. Active EE was 109.70 kcal (26% of daily active EE) during the one-hour HY session, and the mean MET was recorded as 2.57. HRV measurements showed crucial changes. Increased sympathetic activity observed in SDNN, RMSSD, NN50, pNN50, LF/HF, and HF did not reach the initial level after 15 minutes of total recovery time. Conclusions. One hour of HY practice provided moderate EE. Moreover, 10 minutes of supine rest in addition to 5 minutes of the meditation phase of HY practice is not seen as completely effective in improving parasympathetic activity and returning the practitioners to their initial level. Extending the meditation phase at the end of the HY session by more than 10 minutes and measuring the recovery process of HRV could add more detailed results to the literature.

Associations between physical activity and markers of brain pathology in autosomal dominant Alzheimer’s disease: A preliminary report

AbstractBackgroundPhysical activity is a promising lifestyle factor that could protect against memory decline in preclinical Alzheimer’s disease (AD). Greater physical activity has been shown to attenuate the relationship between amyloid‐b and cognitive decline and neurodegeneration in individuals at risk for dementia. Yet, little is known about the relation of physical activity with tau pathology, a strong predictor of cognitive decline. Autosomal dominant Alzheimer’s disease (ADAD) provides a unique opportunity to study preclinical AD since carriers of ADAD mutations are destined to develop dementia at early age, have a well‐characterized disease trajectory, and do not present age‐related comorbidities. We examined physical activity levels in young mutation carriers and non‐carriers from a Colombian kindred with ADAD, and explored the associations among physical activity, brain pathology (amyloid and tau), hippocampus volume, and memory performance.MethodsTen Presenilin‐1 E280A cognitively unimpaired mutation carriers and 23 matched non‐carriers (ages: μ=37.46, σ:6.01) traveled from Colombia to Boston for 11C Pittsburgh compound B‐PET (amyloid), Flortaucipir‐PET (tau), MRI and cognitive testing. All completed the 7‐day Physical Activity Recall questionnaire, which provides a measure of metabolic equivalents (METS) based on an estimate of the energy expenditure for common physical activities. Group differences were tested using the Mann Whitney U test. Linear regressions were used to examine associations between METS, imaging markers, and memory.ResultsCompared to non‐carriers, mutation carriers had greater cortical amyloid (non‐carriers: μ=1.05, σ=0.03, carriers: μ=1.26, σ=0.20, p&lt;.001), and performed worse on the CERAD word list recall test (non‐carriers: μ=7.96, σ=1.24, carriers: μ=5.83, σ=2.75, p=.012). Groups did not differ in age, sex, education or METS (non‐carriers: μ=248.89, σ:27.53; carriers: μ=249., σ:20.81). Further, METS were not significantly associated with pathology levels, age, hippocampus volume or memory. However, those carriers (n=4) with the highest entorhinal and inferior temporal tau burden also had the lowest METS.ConclusionPreliminary findings of this ongoing study suggest that physical activity levels may not be associated with markers of neurodegeneration or memory performance in early preclinical ADAD. Future studies with larger samples and longitudinal follow‐up are needed to better understand the role of physical activity in the risk and progression of AD.

Higher-Impact Physical Activity Is Associated With Maintenance of Bone Mineral Density But Not Reduced Incident Falls or Fractures in Older Men: The Concord Health and Aging in Men Project.

High-impact physical activities with bone strains of high magnitude and frequency may benefit bone health. This study aimed to investigate the longitudinal associations between changes in loading intensities and application rates, estimated from self-reported physical activity, with bone mineral density (BMD) changes over 5 years and also with incident falls over 2 years and long-term incident fractures in community-dwelling older men. A total of 1599 men (mean age 76.8 ± 5.4 years) from the Concord Health and Aging in Men Project (CHAMP) were assessed at baseline (2005-2007) and at 2- and 5-year follow-up. At each time point, hip and lumbar spine BMD were measured by dual-energy X-ray absorptiometry, and physical activity energy expenditure over the past week was self-reported via the Physical Activity Scale for the Elderly (PASE) questionnaire. Sum effective load ratings (ELRs) and peak force were estimated from the PASE questionnaire, reflecting the total and highest loading intensity and application rate of physical activities, respectively. Participants were contacted every 4 months over 2 years to self-report falls and over 6.0 ± 2.2 years for fractures. Hip fractures were ascertained by data linkage for 8.9 ± 3.6 years. Compared with sum ELR and PASE scores, peak force demonstrated the greatest standardized effect size for BMD maintenance at the spine (β = 9.77 mg/cm2 ), total hip (β = 14.14 mg/cm2 ), and femoral neck (β = 13.72 mg/cm2 ) after adjustment for covariates, including PASE components (all p < .01). Only PASE scores were significantly associated with reduced falls risk (standardized incident rate ratio = 0.90, 95% confidence interval 0.81-1.00, p = .04). All physical activity measures were significantly associated with reduced incident fractures in univariate analyses, but none remained significant after multivariable adjustments. Older men who engaged in physical activity of high and rapid impact maintained higher BMD, while higher energy expenditure was associated with reduced falls risk. Coupling traditional physical activity data with bone loading estimates may improve understanding of the relationships between physical activity and bone health. © 2020 American Society for Bone and Mineral Research (ASBMR).

Relationship between primary school healthy eating and physical activity promoting environments and children’s dietary intake, physical activity and weight status: a longitudinal study in the West Midlands, UK

ObjectiveWe aimed to examine the association between food and physical activity environments in primary schools and child anthropometric, healthy eating and physical activity measures.DesignObservational longitudinal study using data from a...

Assessment of Fatigue Using Wearable Sensors: A Pilot Study

Background: Fatigue is a broad, multifactorial concept encompassing feelings of reduced physical and mental energy levels. Fatigue strongly impacts patient health-related quality of life across a huge range of conditions, yet, to date, tools available to understand fatigue are severely limited. Methods: After using a recurrent neural network-based algorithm to impute missing time series data form a multisensor wearable device, we compared supervised and unsupervised machine learning approaches to gain insights on the relationship between self-reported non-pathological fatigue and multimodal sensor data. Results: A total of 27 healthy subjects and 405 recording days were analyzed. Recorded data included continuous multimodal wearable sensor time series on physical activity, vital signs, and other physiological parameters, and daily questionnaires on fatigue. The best results were obtained when using the causal convolutional neural network model for unsupervised representation learning of multivariate sensor data, and random forest as a classifier trained on subject-reported physical fatigue labels (weighted precision of 0.70 ± 0.03 and recall of 0.73 ± 0.03). When using manually engineered features on sensor data to train our random forest (weighted precision of 0.70 ± 0.05 and recall of 0.72 ± 0.01), both physical activity (energy expenditure, activity counts, and steps) and vital signs (heart rate, heart rate variability, and respiratory rate) were important parameters to measure. Furthermore, vital signs contributed the most as top features for predicting mental fatigue compared to physical ones. These results support the idea that fatigue is a highly multimodal concept. Analysis of clusters from sensor data highlighted a digital phenotype indicating the presence of fatigue (95% of observations) characterized by a high intensity of physical activity. Mental fatigue followed similar trends but was less predictable. Potential future directions could focus on anomaly detection assuming longer individual monitoring periods. Conclusion: Taken together, these results are the first demonstration that multimodal digital data can be used to inform, quantify, and augment subjectively captured non-pathological fatigue measures.

Clinical Impact of Nutritional Status and Energy Balance in Elderly Hospitalized Patients.

This study aimed 1) to assess the nutritional status of patients hospitalized in a geriatric ward using the recent Global Leadership Initiative on Malnutrition (GLIM) criteria, 2) to determine the balance between the energy intake (EI) with an enriched diet and the energy requirement (ER) using indirect calorimetry, and 3) to assess whether undernutrition is associated with 1-year outcome. This is a prospective cross-sectional study. This study was performed in a geriatric unit. Patients of this geriatric unit were eligible for the study if they agreed to participate and if they did not meet the exclusion criteria (presence of malignant tumour, uncontrolled heart or renal failure, thyroidal disease, uncontrolled sepsis, oedema of the lower limbs, wearing of a pacemaker, biological thyroid dysfunction and inability to perform walking tests). Rest energy expenditure (REE) was measured by indirect calorimetry within the week of hospitalization. Total energy expenditure (TEE) was obtained by multiplying REE by a physical activity level coefficient and energy expenditure that was related to thermogenesis (i.e., 10% of the total amount of energy ingested over 24 h) was added. Food intake was measured over a 3-day period. Undernutrition was defined using MNA and the criteria of the GLIM leadership. Clinical outcomes included 1-year institutionalisation and mortality. Seventy-nine patients (84.9 ± 5.3 years) were included. A total of 21 (26.6 %) patients were found undernourished. REE was 1088 ± 181kcal/day (17.8 ± 2.9 kcal/kg/day) and TEE was 1556 ± 258 kcal/day (25.4 ± 4.2 kcal/kg/day). Weight-adjusted REE and TEE were higher in undernourished patients compared to those well-nourished (19.8 ± 3.1 vs. 17.1 ± 2.6 kcal/day and 28.4±4.5 vs. 24.4±3.7 kcal/day) (p<0.05). The lower was the Body Mass Index (BMI), the higher was the energy needs (p<0.01). EI was significantly greater than energy requirements (difference requirements - intake with enriched diet = -354 ± 491 kcal/day; p<0.0001). This difference did not depend on BMI (p=0.82), appendicular skeletal mass index (ASMI) (p=0.63), or the presence of undernutrition (p=0.33). At 1-year follow-up, 15 (19%) patients died and 20 (25.6%) were institutionalized. On multivariable analysis, male gender (OR=5.63; p=0.015) and undernutrition (OR=7.29; p=0.0043) emerged as independently associated with death. On multivariable analysis, only ASMI (OR 0.59 (0.35-0.99), p=0.044) and activities of daily living (ADL) (OR 1.14 (1.00-1.30), p=0.043) were significantly associated with institutionalization. Undernutrition as assessed by the GLIM criteria remains common in elderly patients hospitalized in a geriatric unit and is associated with increased 1-year mortality but not with institutionalization. Energy requirements are higher in undernourished patients and in patients with a low BMI. Enriched energy intakes could sufficiently cover the energy needs of this population.

Accelerometer output and its association with energy expenditure in persons with mild-to-moderate Parkinson's disease.

ObjectiveThis study examined the association between ActiGraph accelerometer output and energy expenditure across different speeds of walking in persons with Parkinson’s disease (PD), and further generated cut-points that represent a metric for quantifying time spent in moderate-to-vigorous physical activity (MVPA) among persons with PD.MethodsThe sample included 30 persons with mild-to-moderate PD (Hoehn and Yahr stages 2–3) and 30 adults without PD matched by sex and age. All participants completed 5 minutes of quiet, seated rest and then underwent three, 6-minute bouts of walking on a treadmill at three different speeds relative to the individual’s self-selected pace. Activity counts were measured using an ActiGraph accelerometer worn at the waist level on the least affected side for persons with PD and the dominant side for controls. The rate of oxygen consumption, or energy expenditure, was measured using a portable, open-circuit spirometry system.ResultsOur results indicated a strong association between activity counts and energy expenditure for persons with PD (R2 = 0.87) and controls (R2 = 0.89). However, the significant difference in slopes resulted in a lower cut-point of 1,354 counts·min-1 for persons with PD than the cut-point of 2,010 counts·min-1 for controls.ConclusionOur results support the application of the disease-specific cut-point for quantifying the amount of time spent in MVPA using ActiGraph accelerometers among persons with mild-to-moderate PD. Such an application may provide accurate estimates of MVPA in this population, and better inform future research examining the possible determinants and consequences of physical activity as well as testing of interventions for changing MVPA in PD.

A Randomized Controlled Trial of Ovarian Suppression in Premenopausal Women: No Change in Free-Living Energy Expenditure.

The purpose of this study was to determine whether suppression of ovarian function (gonadotropin-releasing hormone agonist [GnRHAG ]) for 24 weeks in premenopausal women approaching menopause causes changes in body composition and a decline in free-living physical activity energy expenditure (PAEE) and whether endurance exercise training attenuates the changes. Premenopausal women who were approaching menopause (mean [SD]: age 46 [3] years, BMI 26.3 [4.8] kg/m2 ) were randomized to 24 weeks of GnRHAG (n = 14), GnRHAG + Exercise (n = 11), or placebo (n = 9). Endurance exercise was performed 4 days per week with the goal of expending 200 to 300 kcal per session. Primary outcome measurements included body composition by dual-energy x-ray absorptiometry, total daily energy expenditure (TDEE), and PAEE by doubly labeled water, and resting energy expenditure (REE) by indirect calorimetry. Changes in TDEE, PAEE, REE, or body composition were not different between groups. However, within the GnRHAG group, fat mass increased (mean [SE]: total 1.7 [0.4] kg, trunk 0.9 [0.2] kg, leg 0.6 [0.2] kg) and fat-free leg mass decreased (mean [SE]: -0.4 [0.2] kg) significantly. In premenopausal women approaching menopause, ovarian hormone suppression resulted in increased adiposity without alterations in TDEE, PAEE, or REE.

Experimentally Manipulated Low Social Status and Food Insecurity Alter Eating Behavior Among Adolescents: A Randomized Controlled Trial.

This randomized trial experimentally manipulated social status to assess effects on acute eating behavior and 24-hour energy balance. Participants (n = 133 Hispanics; age 15-21 years; 60.2% females) were randomized to low social status ("LOW") or high social status ("HIGH") conditions in a rigged game of Monopoly (Hasbro, Inc.). Acute energy intake in a lunchtime meal was measured by food scales. Twenty-four-hour energy balance was assessed via summation of resting metabolic rate (metabolic cart), physical activity energy expenditure (accelerometer), thermic effect of food, and subtraction of twenty-four-hour energy intake (food diary). In the total sample, no significant differences were observed by study condition at lunchtime. LOW females consumed a greater percent of lunchtime daily energy needs (37.5%) relative to HIGH females (34.3%); however, this difference was not statistically significant (P = 0.291). In males, however, LOW consumed significantly less (36.5%) of their daily energy needs relative to HIGH males (45.8%; P = 0.001). For 24-hour energy balance, sex differences were nearly significant (P = 0.057; LOW females: surplus +200 kcal; HIGH males: surplus +445 kcal). Food-insecure individuals consumed a nearly significant greater lunchtime percent daily energy than those with food security (40.7% vs. 36.3%; P = 0.0797). The data demonstrate differential acute and 24-hour eating behavior responses between Hispanic male and female adolescents in experimentally manipulated conditions of low social status.

Physical activity energy expenditure and fat-free mass: relationship with metabolic syndrome in overweight or obese postmenopausal women.

Menopause transition is associated with detrimental changes in physical activity, body composition, and metabolic profile. Although physical activity energy expenditure (PAEE) is inversely associated with metabolic syndrome (MetS) in individuals at higher risk of cardiovascular disease, the association is unknown in low-risk individuals. The aim of the study was to investigate the association between PAEE and MetS (prevalence and severity) in inactive overweight or obese postmenopausal women with a low Framingham Risk Score (<10%). Cross-sectional data of 126 participants were divided into quartiles based on PAEE (Quartile (Q)1 = lowest PAEE) while fat-free mass (FFM) and fat mass were measured by dual-energy X-ray absorptiometry. MetS prevalence was significantly different between Q1 and Q4 (37.9% vs 13.3%, p = 0.03). After controlling for potential confounders, MetS severity was negatively associated with PAEE (B = -0.057, p < 0.01) and positively with FFM (B = 0.038, p < 0.001). Moderation analyses indicated that a greater FFM exacerbated the association between PAEE and MetS severity in Q1 and Q2 (PAEE × FFM; B = -0.004; p = 0.1). Our results suggest that displaying a low FRS and lower PAEE increase MetS prevalence and severity. In addition, greater FFM interacts with lower PAEE to worsens MetS severity, while higher PAEE lessened this effect. Novelty: Inactive individuals displaying higher daily PAEE also have a lower MetS prevalence. Greater FFM is associated with a worse MetS severity where a higher PAEE mitigated this deleterious effect in our cohort.