Activity For Degradation Research Articles

Lamellar Co3O4/NH2-MIL125 composites: boosting photocatalytic activity and stability for toluene degradation

Lamellar Co3O4/NH2-MIL125 composites: boosting photocatalytic activity and stability for toluene degradation

Synergistic degradation and ecotoxicology assessment of tetracycline by II-scheme Cu3BiS3/Bi2Fe4O9 photocatalytic activation of peroxymonosulfate

The increasing reliance on antibiotics in recent years has led to the growing overuse of antibiotics, and tetracycline (TC) is a widely used antibiotic. In this study, a hierarchical configuration system was constructed by combining Cu3BiS3 and Bi2Fe4O9 for the study of photocatalytic activation of persulfate degradation of TC, and its photocatalytic performance on TC was fully evaluated. Results found that Bi2Fe4O9 and Cu3BiS3 formed a type-II heterojunction, which inhibited the complexation of photogenerated carriers and synergized with peroxymonosulfate (PMS) to promote the generation of reactive radicals and thus enhance the photocatalytic effect. Also, in the photocatalytic activation of persulfate systemCu3BiS3/Bi2Fe4O9/PMS/ visible (Vis), the best catalytic performance of 12.5 %Cu3BiS3/Bi2Fe4O9 was achieved when the catalyst injection was 0.3 g/L, the concentration of TC was 20 mg/L, the concentration of PMS was 1 mmol/L, and the pH=6.5, which degraded 97.9 % of TC within 60 min. The 12.5 % Cu3BiS3/Bi2Fe4O9/PMS/ Vis system has a contribution of active substances of SO4•−>O2•−>h+>O12>•OH. Further, the degradation mechanism and pathways of TC by the Cu3BiS3/Bi2Fe4O9/PMS/Vis system was proposed, and it was proved that the system could realize the safe conversion of TC according to the toxicity estimation using software Toxicity Estimation Software Tool (TEST).

Ag/Bi2WO6 Green Nanocomposites with Highly Efficient Photocatalytic Activity for Dye Degradation and Chromium (VI) Reduction Under Blue LED Irradiation

Ag/Bi2WO6 Green Nanocomposites with Highly Efficient Photocatalytic Activity for Dye Degradation and Chromium (VI) Reduction Under Blue LED Irradiation

MicroRNA-Triggered Programmable DNA-Encoded Pre-PROTACs for Cell-Selective and Controlled Protein Degradation.

Proteolysis-targeting chimeras (PROTACs) have accelerated drug development; however, some challenges still exist owing to their lack of tumor selectivity and on-demand protein degradation. Here, we developed a miRNA-initiated assembled pre-PROTAC (miRiaTAC) platform that enables the on-demand activation and termination of target degradation in a cell type-specific manner. Using miRNA-21 as a model, we engineered DNA hairpins labeled with JQ-1 and pomalidomide and facilitated the modular assembly of DNA-encoded pre-PROTACs through a hybridization chain reaction. This configuration promoted the selective polyubiquitination and degradation of BRD4 upon miR-21 initiation, highlighting significant tumor selectivity and minimal systemic toxicity. Furthermore, the platform incorporates photolabile groups, enabling the precise optical control of pre-PROTACs during DNA assembly/disassembly, mitigating the risk of excessive protein degradation. Additionally, by introducing a secondary ligand targeting CDK6, these pre-PROTACs were used as a modular scaffold for the programmable assembly of active miRiaTACs containing two different warheads in exact stoichiometry, enabling orthogonal multitarget degradation. The integration of near-infrared light-mediated photodynamic therapy through an upconversion nanosystem further enhanced the efficacy of the platform with potent in vivo anticancer activity. We anticipate that miRiaTAC represents a significant intersection between dynamic DNA nanotechnology and PROTAC, potentially expanding the versatility of PROTAC toolkit for cancer therapy.

MicroRNA‐Triggered Programmable DNA‐Encoded Pre‐PROTACs for Cell‐Selective and Controlled Protein Degradation

AbstractProteolysis‐targeting chimeras (PROTACs) have accelerated drug development; however, some challenges still exist owing to their lack of tumor selectivity and on‐demand protein degradation. Here, we developed a miRNA‐initiated assembled pre‐PROTAC (miRiaTAC) platform that enables the on‐demand activation and termination of target degradation in a cell type‐specific manner. Using miRNA‐21 as a model, we engineered DNA hairpins labeled with JQ‐1 and pomalidomide and facilitated the modular assembly of DNA‐encoded pre‐PROTACs through a hybridization chain reaction. This configuration promoted the selective polyubiquitination and degradation of BRD4 upon miR‐21 initiation, highlighting significant tumor selectivity and minimal systemic toxicity. Furthermore, the platform incorporates photolabile groups, enabling the precise optical control of pre‐PROTACs during DNA assembly/disassembly, mitigating the risk of excessive protein degradation. Additionally, by introducing a secondary ligand targeting CDK6, these pre‐PROTACs were used as a modular scaffold for the programmable assembly of active miRiaTACs containing two different warheads in exact stoichiometry, enabling orthogonal multitarget degradation. The integration of near‐infrared light‐mediated photodynamic therapy through an upconversion nanosystem further enhanced the efficacy of the platform with potent in vivo anticancer activity. We anticipate that miRiaTAC represents a significant intersection between dynamic DNA nanotechnology and PROTAC, potentially expanding the versatility of PROTAC toolkit for cancer therapy.

Antioxidant and pH-dependent cationic and anionic dye degradation activities of optimum synthesized organic@inorganic Cu hybrid nanoflowers

First time in this study, hybrid Cu nanoflowers (Cu hNFs) were synthesized with Cystosphaera jacquinotii algae extract and the pH-dependent catalytic activities of hNFs synthesized under optimum conditions against brilliant blue and methylene blue dyes were determined. Ideal morphology of hNFs, were synthesized by using 1 ml extract in PBS (pH 7.4). The diameter and petal thickness of optimum synthesized hNF were 7–22 µm, and 35.5 nm, respectively. Main skeleton component (C, O, P, and Cu) of hNFs were determined by EDX. The presence of functional groups and primary phosphate crystals formed by Cu and phosphate reaction in the PBS buffer were confirmed by FT-IR analysis. The hNFs exhibited the antioxidant activity (IC50 = 1.27 mg/ml, R 2 = 0.6971) against to DPPH (2,2-diphenyl-1- (2,4,6-trinitrophenyl) hydrazyl). hNFs degraded methylene blue and brilliant blue dyes at the highest at pH 9 (73.85%) and pH 5 (68.19%) media, respectively. Catalytic activities of hNFs against methylene blue and brilliant blue dyes were explained by Fenton mechanism. The findings are thought to be used in new type hNF synthesis and various environmental applications.

Optimization of waste biomass demineralization through response surface methodology and enhancement of thermochemical and fusion properties

This study examines the impact of leaching with dilute hydrochloric acid solution on the reduction of ash content and the thermal degradation behavior of sugarcane bagasse. Response surface methodology (RSM) was used to statistically design the experiments and investigate the effect of three independent variables: treatment time, solid-to-liquid ratio, and reagent concentration. The leaching conditions were further optimized and experimentally validated for maximum ash reduction for suitability of treated biomass as feedstock for thermochemical conversion technologies. Reagent concentration and treatment time directly affected ash reduction, while the solid-to-liquid ratio inversely influenced it. Concentration had the highest impact, and treatment duration had the least. The maximum 78.2% ash reduction was achieved by treating the biomass with 1 M HCl for 80 min at a solid-to-liquid ratio of 50:1 (wt/vol). This ash reduction also resulted in a 9.82% increase in higher heating value (HHV). Hemicellulose hydrolysis during leaching was observed through chemical composition and Fourier-transform infrared spectroscopy (FTIR). Ash fusion temperatures increased, indicating more thermally stable biomass. Thermogravimetric analysis (TGA) showed elevated maximum degradation temperature and activation energy.

Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy.

Molecular glue degraders (MGDs) are proximity-inducing agents that mediate the cooperative interaction between a target protein and an E3 ligase, introducing an additional layer of specificity beyond that afforded by traditional small molecules. Historically, molecular glues that stabilize protein-protein interactions were often discovered serendipitously. In this study, we leveraged the reprogramming potential of cereblon (CRBN)-based ligands and conducted a CRBN-dependent proliferation screen to identify CRBN-based MGDs capable of inducing the degradation of proteins essential for cell viability. Through our screening and subsequent medicinal chemistry optimization, we identified dCK1α-1 as a potent and selective CK1α-targeting molecular glue degrader. Furthermore, we synthesized an orally active derivative, dCK1α-2, with enhanced pharmacokinetic properties, which exhibited pronounced degradation activity and demonstrated efficacy in mouse models following oral gavage. These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.

Construction and degradation mechanism of the magnetic CoFe1.95Y0.05O4/Ag/g-C3N4 Z-scheme heterojunction for enhanced photocatalytic activity

In this study, a Z-scheme heterojunction CoFe1.95Y0.05O4/Ag/g-C3N4 (CFYO/ACN) magnetic nanocomposite was prepared by hydrothermal synthesis. The composite was characterised and analyzed using different characterization tools and its photocatalytic degradation activity towards methylene blue (MB) was investigated. The results showed that the CFYO/ACN photocatalyst compared to CoFe1.95Y0.05O4 (CFYO) and Ag/g-C3N4 (ACN), the composite CFYO/ACN had the highest degradation efficiency of MB, which was up to 97 % within 120 min, which was 1.26 and 1.09 times higher than that of ACN and CFYO, respectively. The enhancement of the catalytic performance of CFYO/ACN was attributed to the fact that the heterogeneous junction formation effectively inhibited the complexation of photogenerated carriers. In addition, five consecutive cyclic degradation experiments showed that CFYO/ACN exhibited efficient photocatalytic degradation, stable crystal structure, and easy recycling in the photodegradation process. Finally, the capture experiments confirmed that superoxide radicals (⋅O2−) and hydroxyl radicals (·OH) play a major role in the degradation process. This study provides an effective strategy for the construction of efficient photocatalysts.

Fungal Extracellular Enzymes from Aspergillus spp. as Promising Candidates for Extra-Heavy Oil Degradation and Enhanced Oil Recovery.

Heavy crude oil (HCO) and extra-heavy crude oil (EHCO) with high viscosity and density pose enormous challenges to the exploitation of oil reserves. While bacteria are increasingly used in biocatalytic upgrading of HCO and EHCO, less attention has been paid to the potential of fungi. The aim of this study was to ascertain the role of fungal extracellular enzymes from Aspergillus spp. In the biodegradation of EHCO and their application potential for enhanced oil recovery. A. terreus HJ2 and A. nidulans HJ4 with the ability to biodegrade HCO were previously isolated from bitumen enrichment cultures. Both strains grew well on EHCO agar plates supplemented with a small amount of soluble starch (0.2%) and yeast extract (0.3%). Extracellular enzymes from each strain separately, as well as mixtures of the enzymes, exhibited EHCO degradation activity, leading to redistribution of hydrocarbons with substantial formation of biogases and organic acids in a 7-day period. Enzymatic degradation resulted in decreased contents of resins and asphaltenes, accompanied by increased contents of saturates and aromatics. Gas chromatography-mass spectrometry revealed distinct redistribution patterns of n-alkane in the biotreated oil. Enzymatic degradation additionally caused considerable reduction in oil viscosity (by 12.7%) and heavy metal concentrations (Ni, by 44.1%; Fe, by 54.0%; V, by 31.6%). The results provide empirical evidence for the application potential of fungal extracellular enzymes from Aspergillus spp. in EHCO recovery and biocatalytic upgrading of EHCO.

Ion-exchange formation of Ag2CO3-Ag3PO4 binary nanostructure on electrospun polyurethane nanofibers for enhanced photocatalytic degradation and antibacterial activities

In this study, a hybrid Ag2CO3-Ag3PO4/PU NFs membrane was prepared by electrospinning followed by ion-exchange methods. The obtained samples were characterized by SEM, EDS, XRD, and IR techniques. The Ag2CO3-Ag3PO4/PU NFs membrane composite exhibited excellent photocatalytic performance (100 % of the dye removal within 70 min) towards the degradation of methylene blue (MB) under visible light irradiation. This remarkable performance was mainly due to the efficient separation of the photogenerated charge carriers. In addition, the composite showed good antibacterial performance against Salmonella typhimurium and Staphylococcus aureus. The results obtained from the photocatalytic and antibacterial studies showed that the prepared material can be proposed as a multifunctional material in wastewater treatment and environmental applications.

Myroides species, pathogenic spectrum and clinical microbiology sight in Mexican isolates.

Myroides is a bacterial genus of opportunistic bacteria responsible for diverse infections including in the skin and soft tissues, urinary tract, cardiovascular system, and bacteremia, although the incidence of its reported infections is low, it is increasing, likely due the use of better bacterial identification methods, but also perhaps due an increase in its prevalence. In addition, their pathogenic role is limited in terms of reporting their microbial physiology, so the present work provides information in this regard in addition to the information that is available in the international literature. To describe the microbiological and genetic characteristics of seven different Myroides spp. clinical strains and comment on their phylum, pathogenic and resistance characteristics. Seven Myroides spp., strains associated with infections were included from 1/January/2012 to 1/January/20 and identified by miniaturized biochemistry and MALDI-ToF. Susceptibility tests were performed according to CLSI recommendations by broth microdilution. Whole genome sequencing was performed for each strain and bioinformatics analysis were performed. Strains were identified at genus level by two methodologies. Our results revealed that likely four strains belong to the species Myroides odoratimimus, while the other two may be undescribed ones. Remarkably, all isolates harbored several genes encoding antibiotic resistance determinants for ß-lactams, aminoglycosides and glycopeptides and in concordance, presented high levels of resistance, against these antibiotics (AK and GN both 100%, ATM, CAZ and FEP 100%, e.g.); moreover, the presences of carbapenemases were evidenced by meropenem (mCIM) and imipenem (CARBA NP) degrading activity in six isolates and two strains possessed plasmids harboring mainly ribosomal RNA genes, tRNAs and genes encoding proteins with unknown functions. Our study increases the knowledge about the biology of this understudied genus and highlights the potential of Myroides to emerge as a broader cause of recalcitrant opportunistic infections.

Enhanced photocatalytic degradation of organic pollutants by randomly oriented 2D SnS2 nanostructures

Abstract In this study, we present a bottom-up solvothermal technique using tin tetrachloride pentahydrate (SnCl4.5H2O) and thioacetamide as precursors to synthesize SnS2 nanostructures. Different solvents including isopropyl alcohol, ethanol (EN), and ethylene glycol were used in the reaction to enhance the photodegradation efficiency of organic pollutants, Methylene Blue (MB), and Tetracycline (TC) in an aqueous medium under simulated solar light irradiation. The SnS2 nanostructures synthesized with these solvents were characterized using various structural, morphological, and optical techniques, including x-ray diffraction, RAMAN, field emission scanning electron microscope, x-ray photoelectron spectroscopy, UV–Vis, and Brunauer–Emmett–Teller analysis. The choice of solvent was found to significantly affect the structural, morphological, and optical properties of the SnS2 nanostructures. Notably, the sample synthesized with EN as the solvent displayed a unique morphology, enhanced light-harvesting ability, efficient charge carrier separation, and a larger specific surface area, all of which contributed to its superior photocatalytic activity. This sample achieved 99.9% degradation of MB and 95% degradation of TC within 20 and 40 min, respectively. The kinetic analysis revealed maximum rate constant (k) values of 0.15242 min−1 for MB and 0.060 95 min−1 for TC, as determined by the pseudo-first-order kinetic model. We also discuss the plausible mechanism involving visible light-induced electron–hole pairs that generate reactive species, leading to the mineralization of dyes into H2O, CO2, and other gaseous products. The synthesized SnS2 nanostructures demonstrate significant potential for enhanced photocatalytic activity in organic pollutant degradation, underscoring their promise in addressing water pollution challenges.

Efficient RhB degradation and antimicrobial activity with molecular docking study of polymers doped ZnSe nanostructure

A facile coprecipitation approach was adopted to synthesize zinc selenide (ZnSe) doped with a fixed amount (3 wt%) of cetyltrimethylammonium bromide (CTAB) and different concentrations (2 and 4 wt%) of eudragit to form ternary nanostructure (NSs). Eud and CTAB inhibit the dimension and reduce the rate of recombination of NSs to intensify catalytic performance against rhodamine B (RhB) and bactericidal action against MDR Staphylococcus aureus (S. aureus). Doped ZnSe increase active sites, porosity, and surface area to enhance the degradation of RhB dye and antimicrobial efficacy to kill pathogenic S. aureus. Assessment of 4 wt% Eud/CTAB exhibited effective performance for degradation of RhB and bactericidal potential highlights an impressive 94.3 % degradation efficiency and 8.85 ± 0.05 mm of the inhibition zone against MDR S. aureus. Computational molecular docking studies suggest that NSs, such as Eud/CTAB-doped ZnSe, have the ability to inhibit the DNA gyrase enzyme in MDR S. aureus.

Green synthesized nano-TiO2 from Tamarindusindica leaf extract for photo-degradation of combination of dyes by suspension and immobilization on inert supports

ABSTRACT The present study aims to use green synthesized TiO2 as a photocatalyst in suspended and immobilized form under UV light to efficiently degrade a combination of reactive dyes, namely titan yellow, methyl orange, rhodamine B, and methylene blue. TiO2 nanoparticles (NPs) were synthesized using Tamarindus indica leaf extract and were utilized to parametrically study photo-degradation at room temperature. The green synthesized NPs were characterized by Powder XRD, SEM, and FTIR techniques to understand the crystalline phase/purity, morphology, and functional groups respectively. The TiO2 in suspension under UV light showed >90% degradation towards a 10 ppm composite dye at a loading of 1.5 gL−1, pH 7, and an irradiation time of 120 min. Subsequently, TiO2 was further immobilized in-situ, on inert supports of perlite granules and glass and studied for catalytic activity in batch and continuous modes. The TiO2 nanoparticles immobilized on perlite granules and glass showed 59 and 48% degradation in batch operation under the same conditions as in suspended form. In continuous mode, the highest degradation activity was recorded at 2 Lh−1 after 4 passes. Further, kinetic studies reveal that the degradation reaction is best described by Langmuir Hinshelwood kinetics for both suspended and immobilized TiO2.

Unraveling new reactivity pathways of cobalt(II) ammonium phosphate toward activation of peroxymonosulfates and subsequent degradation of antibiotic pollutants in water

This study is aimed at unraveling the catalytic activity of cobalt(II) ammonium phosphate (NH4CoPO4) in activation of peroxymonosulfate (PMS) and degradation of various antibiotics. It was found that NH4CoPO4 enabled swift and efficient removal of ciprofloxacin (CIP) at a high initial concentration (30 mg/L) using very low catalyst loading (10 mg/L) in just several minutes of the reaction. The CIP degradation rate in the presence of NH4CoPO4 was approximately 3.5 times higher than that observed for the well-known and highly active Co3O4 catalyst (k = 0.121 vs. 0.031 min−1, respectively). Catalytic tests with the use of reactive oxygen species scavengers revealed that the primary oxidizing agent responsible for degradation of CIP were cobalt(IV)-oxo species. It was also established that NH4CoPO4 could efficiently degrade CIP even in environmental water samples (e.g., river water). This study contributes to a better understanding of the reactivity of NH4CoPO4 in the degradation of antibiotic pollutants.

Magnetic Fe3O4 nanoparticles supported on carbonized corncob as heterogeneous Fenton catalyst for efficient degradation of methyl orange

The pollution especially organic dyes pollution of water resources is an urgent issue to be solved. It is crucial to develop highly efficient, low cost and recyclable heterogeneous catalysts for wastewater treatment. In this study, a heterogeneous Fenton catalyst loaded with Fe3O4 nanoparticles was prepared by one step pyrolysis using natural crop waste corncob as carbon source. The prepared porous carbon catalyst can effectively degrade methyl orange (MO, 25 mg·L−1) at room temperature, and the degradation rate is 99.7%. In addition to high catalytic degradation activity, the layered porous carbon structure of the catalyst also provides high stability and reusability. The degradation rate can be maintained above 93% after 10 cycles. Furthermore, the prepared catalyst is magnetic, which makes the catalyst easy to recycle in practical applications. In addition, the prepared Fe3O4/RCC catalyst has efficient Fenton degradation activity for bisphenol A (BPA) (96.9%) and antibiotic tetracycline hydrochloride (TC-HCl) (95.5%), which proves that it has universal applicability for the degradation of most organic pollutants. This study provides a feasible and scalable strategy to prepare a heterogeneous Fenton catalyst treating wastewater and high-value utilization of biomass waste.

Fe incorporation and modulation of oxygen vacancies in ZnO nanoparticles for photocatalytic degradation of Rhodamine B

In this study, self-assembled ultrafine nanoclusters of Fe2O3 supported with defective Fe-doped ZnO nanoparticles (NPs) prepared via calcination of a Fe/Zn precursor in the presence of deep eutectic solvents (DES) complex. During the calcination process, surface defects are generated through the decomposition of Fe/Zn precursor with DES complex, simultaneously crystallinity of catalysts improved. The hexagonal wurtzite structure of ZnO NPs is retained after the incorporation of Fe atoms into the ZnO crystal lattice. Notably, the particle size is reduced from 32 to 22 nm after Fe incorporation due to alterations in the nucleation center in the ionic solvent. Electron paramagnetic resonance analysis reveals a broad peak at a g value of 2.0, attributed to Fe3+ atoms doped into ZnO matrix. These doped Fe3+ atoms create additional active sites on the surface of NPs, leading to an extended photoluminescence lifetime of the Fe2O3/ZnO nanocomposite. Consequently, the optimized Vo-Fe/ZnO nanocomposite achieves a 95 % removal efficiency for Rhodamine B (RhB) degradation with a rate constant (k) of 0.0755 min−1. Additionally, nanocomposite shows visible light photo-Fenton activity for RhB degradation with k of 0.0069 min−1.

Uv-activated Ni ions as electron donors for in-situ generation of tunable oxygen vacancies on the surface of Bi2O2CO3 with improving photocatalytic activity for sulfadiazine degradation

In this study, a simple UV-mediated method for creating oxygen vacancies in Bi2O2CO3 is explored. Traditional methods have drawbacks like stringent conditions and difficulty in control. Here, Ni ions embedded in the layers of Bi2O2CO3 act as electron donors, generating oxygen vacancies in situ at room temperature and atmospheric pressure without additional reducing agents. Characterization via ESR, XPS, and other techniques shows a positive correlation between oxygen vacancy concentration and UV irradiation duration. The mechanism of in situ generation under Ni ion doping and UV irradiation is discussed. Additionally, the ability of BOC/Ni-X (Bi2O2CO3 with X minutes of irradiation) catalysts to degrade sulfadiazine under visible light is investigated. Results indicate that controlling irradiation time allows fabrication of Bi2O2CO3 with suitable band gaps, enhancing its ability to degrade sulfadiazine. The initial Bi2O2CO3 material could only remove 5 % of sulfadiazine after 60 min of degradation, while the best modified material with 50 min of light exposure had a removal rate of 90 % for sulfadiazine. This study offers a new approach for constructing oxygen vacancies in metal oxide nanomaterials at room temperature and atmospheric pressure.

Magnetic biochar generated from oil-mill wastewater by microwave-assisted hydrothermal treatment for sonocatalytic antibiotic degradation

The pollution risks of biomass-containing and antibiotics-containing wastewater mean that it must be treated before discharge into the environment. In a process following circular economy principles, oil-mill wastewater (OMWW) was treated in a microwave-assisted hydrothermal process and with simultaneously fabricated magnetic biochar (MBC), which was used as a catalyst for the sonocatalytic degradation of antibiotics metronidazole (MET) and ciprofloxacin (CIP) in aqueous solutions. FeCl3·6H2O, FeCl2·4H2O, and KOH were added to the OMWW, which was then treated in a SynthWave microwave reactor under either a nitrogen or air atmosphere. The UV254 and COD removal efficiencies of the OMWW reached 42.3% and 60.6%, respectively, after treatment at 250 ℃ for 3h. The MBC obtained from the OMWW treatment with air exhibited the highest adsorption and catalytic activity for antibiotics degradation. The synergistic effects of combining adsorption and sonolytic removal were in the ranges of 0.76-3.07 (MET) and 0.75-3.17 (CIP), resulting in significant degradation rate constants of pseudo-first-order kinetics (k1) that ranged from 0.010 to 0.086min-1 (MET) and from 0.018 to 0.050min-1 (CIP). Hydrophobic MET underwent faster degradation than hydrophilic CIP. The •OH is crucial for removing the model antibiotics. Initial antibiotics concentration, reaction volume, ultrasonic frequency, and power had clearer impacts on antibiotics degradation than bulk temperature. Furthermore, the possible sonocatalytic degradation pathways have also been proposed herein. The absorbents and catalysts were derived during the purification of OMWW and subsequently used for antibiotics removal from water, becoming an innovative case of circular economy and sustainable waste treatment.