The task of minimizing pitfall in quantitative reservoir assessment and evaluation is an integral aspect of any promising petroleum exploration and evaluation project. The Niger Delta oil province in Nigeria is chiefly composed of several pay zones with many stratigraphic intervals of sand and shale formations in varying proportion. Whereas conventional seismic interpretation technique poses certain degree of uncertainty in reservoir characterization, seismic inversion constraint by log data brings significant improvement in interpretation that reduces uncertainty in the delineation of reservoir characteristics, volume and distribution. In this present study, post-stack seismic inversion and seismic attributes analysis were used to evaluate the potentials and prospects of mapped reservoirs in a field, offshore depobelt, Niger Delta. The implementation of the tasks consists of mapping of structural framework, horizon picking, log editing and correlation, wavelet extraction, building of low-frequency model, acoustic impedance inversion and crossplot analysis of reservoir properties and attributes. A hybrid approach (formulated using Greenberg-Castagna equation) specific for the Niger Delta depobelts was used to estimate and generate shear wave velocity for the wells. Results obtained from inversion depict an acoustic impedance values in the range 150–280 ft/s g/cc and $$V_{\text{P}}/V_{\text{S}}$$ of 1.25–2.50 at a depth range of 9250–9280 ft within the hydrocarbon-bearing sands in the two wells. Region of low acoustic impedance (representing high reservoir porosity) coupled with a corresponding low $$V_{\text{P}}/V_{\text{S}}$$ ratio (indicating hydrocarbon accumulation) is presumed to have high prospects for exploration and well development. Altogether the degree of correlation between the inverted and actual impedance was found to be about 90% across the wells. It is evident that the acoustic impedance slice at 3000 ms depicts low acoustic impedance sand within 18,500–20,000 ft/s g/cc at the northeastern and southeastern regions of the field. High reflection amplitudes (bright spots) signifying hydrocarbon accumulation are also revealed on seismic attribute maps with surrounding shale diaper as the source rock. This study has revealed the prospect (i.e., existence of active petroleum system of probable economic value) of the delineated field in the Niger Delta depobelt.