Background: Burn injuries are among the most severe types of child injuries, leading to significant functional, social, and psychological disabilities. Physiotherapy plays a crucial role in the rehabilitation of pediatric burn patients, and caregivers are essential in facilitating the treatment process. Understanding caregivers' perceptions and adherence to physiotherapy treatment can inform better care strategies. Objective: This study aimed to assess the perceptions of caregivers towards physiotherapy treatment for pediatric burn patients and to evaluate adherence to prescribed exercise regimens. Methods: A descriptive cross-sectional study was conducted from June 2023 to December 2023. Data were collected from caregivers at two public hospitals and one private rehabilitation center using a non-probability convenience sampling method. The sample included 53 caregivers of children aged 1-5 years with burn injuries covering more than 20% of their total body surface area and who had been undergoing physiotherapy for 3-4 weeks. Exclusion criteria were caregivers not actively involved in daily care, those unable to communicate in English or Urdu, and patients without a caregiver. Data were collected using a semi-structured questionnaire based on the Measure of Processes of Care (MPOC). The questionnaire was validated and had a Cronbach’s alpha of 0.703. Data were analyzed using SPSS version 25, with descriptive statistics presented as frequencies, percentages, means, and standard deviations. Results: Among the caregivers, 64.2% were mothers, 15.1% were fathers, and 20.8% were other relatives. A total of 81.1% of caregivers agreed and 18.9% strongly agreed that the physiotherapist encouraged active participation in decision-making. Comfort in discussing concerns was reported by 69.3% agreeing and 18.9% strongly agreeing. Emotional and social aspects were adequately addressed according to 39.6% of caregivers, with 41.5% neutral and 15.5% disagreeing. Clear communication of treatment plans was reported by 75.5% agreeing and 24.5% neutral. Adherence to exercise routines varied, with 47.2% often, 32.1% always, and 20.8% sometimes helping with exercises. However, 39.6% reported that the child always refused to do exercises, and 64.2% noted the child always complained of pain during therapy. Conclusion: The study concluded that caregivers generally have a positive perception of physiotherapy for pediatric burn patients and actively participate in their care. Challenges such as pain during exercises and time constraints highlight the need for enhanced support and communication to improve adherence and outcomes.