Active Involvement Research Articles

Complex case of multiple sclerosis with multiple demyelinating locations

Multiple sclerosis (MS) is a chronic inflammatory disorder with an unpredictable progression that affects the central nervous system and has significant emotional, social, and professional implications. The therapeutic approach is multifactorial and requires complex management coordinated by a specialized, multidisciplinary team over the long term. Current non-pharmacological treatment strategies under study, which may improve the course of the disease, focus on the gut microbiome and include the administration of probiotics and fecal transplantation. This study presents a case of secondary progressive multiple sclerosis in a young patient, with rapidly progressive evolution despite ongoing background therapy. The study analyzed literature data regarding both medical rehabilitation programs used in secondary progressive multiple sclerosis and other therapeutic strategies that can improve the quality of life. Medical rehabilitation has no proven impact on disease progression but can enhance the quality of life for patients with multiple sclerosis through spasticity management, improved mental health, increased mobility, and muscle strength. These therapeutic strategies can improve involvement in professional activities and participation in social and family life for patients with multiple sclerosis.

Multidimensional Approach to Curriculum Transformation in Increasing Multicultural Appreciation

The need for curriculum transformation in Indonesia to support multicultural education is increasingly evident. This study focuses on how a multidimensional approach to curriculum transformation can effectively enhance students' appreciation of multiculturalism. This approach fosters tolerance and respect for cultural, ethnic, and religious diversity. This study used qualitative methods. Data were collected through in-depth interviews and documentation. Data analysis using thematic coding and triangulation techniques to ensure data validity, consistency, and reliability of findings. Curriculum transformation at State Junior High School I Medan integrates cognitive, affective, psychomotor, and socio-cultural dimensions to foster multicultural appreciation. Key changes include shifting the curriculum's focus from academic achievement to developing tolerance and respect for cultural diversity. Teaching materials now incorporate multicultural perspectives, and project-based participatory learning methods actively engage students in cultural activities. Classrooms are organized to promote gender and religious balance, and assessments are more holistic, evaluating students' academic performance and involvement in multicultural activities. This transformation creates a more inclusive and culturally responsive educational environment, helping students develop the academic and socio-emotional skills needed to live in a diverse society. This approach prepares students to be more tolerant and inclusive, positively impacting their interactions in an increasingly globalized world. This research provides valuable insights for educators and policymakers on increasing multicultural appreciation among students.

An estimation of the tower crane safety risk factors in the Vietnamese construction industry

The construction industry is among the riskiest sectors worldwide due to its involvement in complex and hazardous activities, primarily because of the use of tower cranes. Tower cranes are considered the most hazardous construction machinery, contributing to a high rate of serious accidents, including fatalities and disabling injuries, not only in Vietnam but also globally. In this paper, we identify and evaluate 42 tower crane safety risk factors specific to the Vietnamese construction industry based on their probability of occurrence, severity of impact, and associated risk levels. The paper reveals that the most probable risk factor is “Unfavorable winds (including intensity, direction, etc.)” with a mean value of 3.641. The factor with the highest severity is “Wire rope is broken” with a mean value of 4.179. Furthermore, the study shows that twenty-five out of forty-two (59.52%) factors present a moderate risk level, with a Relative Significant Index Score (RSIS) ranging from 8.019 to 13.047. Among these, the factor “Bad maintenance management of the tower crane and auxiliary aids” poses the highest risk level, with an RSIS value of 13.047. This paper aims to enhance the understanding oftower crane safety among subcontractors, government safety regulators, main contractors, maintenance personnel, and workers in the Vietnamese construction industry. Additionally, the methodology presented in this paper can be adapted for assessing safety risk factors in other industries within Vietnam.

Ювенальна превенція в Україні: функціональні особливості в період воєнного стану

It was found that Ukraine has ratified and implements the norms of international legislation related to the protection of children’s rights, in particular, by means of criminal law. The activity of juvenile prevention bodies in Ukraine is extremely important in the conditions of martial law for the implementation of the principles of international humanitarian law regarding the safety of childhood and national norms for the protection of the fundamental rights of the child. Juvenile prevention bodies concentrate their activities on the prevention of offenses committed by children, on the detection, termination and disclosure of criminal offenses committed by children on the basis of measures provided for by current legislation. It was emphasized that it is important to identify the reasons and conditions that contribute to the commission of offenses by minors and, within the limits of their competence, to stop and eliminate illegal acts. Very often, the main work is carried out on the basis of the fact that minors have committed an offense. For a person who is just forming his life values and determining the directions of self-realization, it is important to focus on legitimate self-determination. In this process, preventive activities and cooperation of educational institutions, families and representatives of law enforcement agencies, juvenile police are important. It is noted that today in Ukraine, an important area of activity of juvenile police representatives is work with children who are internally displaced persons. Such minors may more often become involved in illegal activities due to the fact that they are in a state of stress associated with a change in their usual living conditions. Offenders can take advantage of the child’s condition and involve himin illegal activities both directly and through social networks. Attention is focused on the fact that wartime realities prove the importance of enhanced protection of childhood and motherhood in Ukraine, as well as the need for competent authorities to actively work with minors to preserve their lives and health, because today law enforcement agencies are faced with new problems related to the violation children’s rights, which are caused by active hostilities, illegal removal of children to the territory of Russia, loss of relatives and housing by minors, their involvement in illegal activities, in particular, in the temporarily occupied territories.

Сравнительный анализ развития Eдиных Информационных Систем Здравоохранения (ЕИСЗ) в странах Африки, Северной Америки и Европы: проблемы и перспективы.

This study presents a comparative analysis of the development of unified healthcare information systems (UHIS) in North America, Europe, and Africa. The research examines key aspects of UHIS implementation, including population coverage by electronic health records, telemedicine development, system interoperability, and regulatory frameworks. The analysis revealed significant regional differences in approaches to healthcare digitalization and UHIS implementation levels. North America is characterized by high digital technology adoption but faces challenges in integrating disparate systems. The European region shows heterogeneity, with Northern European countries leading, while Southern and Eastern Europe lag in UHIS development. The African continent presents the most contrasting picture, with a small group of leading countries and most states in the early stages of digitalization. The study identified common challenges across all regions, including ensuring interoperability, protecting personal data, and overcoming healthcare professionals' resistance to change. Special attention is given to innovative approaches, such as the use of mobile technologies in Africa to overcome infrastructure limitations. The research results emphasize the need for a comprehensive approach to UHIS implementation, considering not only technological but also socio-economic factors. The study concludes that successful UHIS development requires a clear national strategy, adequate funding, and active involvement of all stakeholders.

Analisis Resistensi Pegawai Dalam Kebijakan Jam Kerja di Dinas Pendidikan Kota Gunungsitoli

This research aims to analyze employee resistance to the working hour policy at the Gunungsitoli City Education Office, which has an impact on the effectiveness of public services. The research method used is descriptive qualitative, with data collection through observation, interviews, and documentation. The results show that employee resistance is mainly influenced by a strong organizational culture, incompatibility with the new policy, and lack of employee participation in the policy planning process. The study found that such resistance resulted in decreased work discipline, which negatively impacted the quality of public services. The discussion of the results underscores the importance of inclusive and transparent management strategies in designing and implementing policies, to improve employee compliance and reduce resistance. The conclusion of this study confirms that active involvement of employees in policy planning and participatory approaches can minimize resistance and improve organizational performance and the quality of public services at the Gunungsitoli City Education Office.

Weaving the Web to achieve the SDGs: the presence of women in the boardrooms as a key driver

Purpose Due to the importance of mitigating the issues that afflict society and natural habitats on a global scale, the United Nations has established 17 key goals to directly and effectively mitigate problems such as extreme poverty, lack of access to quality educational environments or the loss of life in underwater and terrestrial ecosystems, which need to be addressed from multiple parties, particularly from the business network. In this context, the purpose of this paper is to analyse the potential impact of female participation in boardrooms on the disclosure of corporate information regarding the integration of the Sustainable Development Goals (SDGs) into business strategy. Design/methodology/approach The research hypotheses were developed on the basis of a multi-theoretical perspective, which included agency theory, upper echelon theory, resources dependency theory and critical mass theory. The hypotheses were tested using a regression model for a sample of 8,903 companies for the period 2019–2022. Findings The results highlight the importance of an increase in female boardroom representation as a key driver in the achieving of the SDGs with favourable effects on environmental and social issues, being robust to changes in methodological specifications. Research limitations/implications This research provides valuable evidence for the analysis of gender issues in the business field; however, it has some limitations that can be addressed by academics. In this sense, this research solely examined the impact of chief executive officer (CEO) duality while overlooking the potential for its influence to be amplified by a distinctive configuration of the board, such as the involvement of a former CEO, a greater or lesser degree of participation of executive directors in the boardroom or the fact that the CEO is a woman. These factors could either reinforce or obstruct the benefits of female directors in the accomplishment of the SDGs. Practical implications From a practical standpoint, this research illustrates the advantages of the active involvement of women in the boardroom. Their participation has resulted in notable modifications to corporate strategies, with a focus on aligning business actions with the attainment of the SDGs and related transparency. This facilitates a more comprehensive understanding of the business interest in conserving natural habitats and eradicating social inequalities. Social implications From a societal perspective, the findings illustrate the significance of actively promoting the involvement of women in organisational leadership roles. The inclusion of women's perspectives can enhance the planning of business processes, with far-reaching implications for stakeholders. Therefore, it is vital to guarantee opportunities for women, such as access to higher education and gainful employment, particularly in nations where there are considerable constraints to the intellectual and economic advancement of girls and women. Originality/value The findings contribute to the growing body of knowledge on the optimal configuration of the boardroom, especially the gendered boardroom (i.e. García-Sánchez et al., 2023b; Liao et al., 2015), and its ability to address today's global challenges. Furthermore, the findings indicate the necessity of establishing pathways for women to reach positions of influence within the organisational hierarchy, thereby facilitating beneficial societal changes. These changes can include the mitigation of environmental damage and the rectification of historical social inequalities.

Integrating theory and practice: knowledge exchange and engagement of nursery managers in ecological restoration

Ecological restoration requires the social collaboration of all stakeholders. Native plant nursery managers potentially possess substantial knowledge in native plant cultivation derived from their practical experience, and they could also be consumers of information generated by scientists. Furthermore, their active involvement in various stages of restoration projects could enhance efficiency and ensure successful outcomes. In this study, nursery managers from Argentina associated with restoration projects were surveyed to assess their level of knowledge exchange with the scientific community, the degree of participation in restoration projects, and their perceptions regarding this collaboration. The surveys were completed by 39 nursery managers from native plant nurseries in Argentina. Our findings indicated that, although nursery managers often adopted scientific protocols, there remains a significant communication gap between scientists and nursery managers. Nursery managers contributed beyond seedling production, including planning, planting, maintenance, and environmental education. Despite recognizing its importance, few nursery managers participated in project evaluations. Nursery managers could serve as both providers of cultural and practical insights and receivers of novel knowledge from the academic‐scientific realm. Moreover, as the nursery managers are familiar with the local context and can potentially facilitate connections with other local stakeholders, their involvement as additional social actors not only enhances the success but also adds legitimacy to the restoration projects they engage in. Such collaboration is crucial for achieving the goals of both international and national restoration initiatives.

Consensus and controversies on post-acute care decision making and referral to geriatric rehabilitation: A national survey

BackgroundTransitioning older hospital patients to the appropriate type of post-acute care has become an urgent clinical issue within the context of changing demographics and limited duration of hospital stay. ObjectiveConsensus on assessments that guide post-acute care decision making would benefit potential patients and support cooperation between settings. DesignA national web-based questionnaire focusing on professional contributions, patient involvement and the use of triage items and measures. ParticipantsHospital and geriatric rehabilitation professionals in the Netherlands participated as respondent groups, representing ‘sending’ and ‘receiving’ professionals. MethodsA comprehensive questionnaire was used with open, multiple choice and closed questions, exploring in detail how assessment of hospital patients in need of a post-acute care decision was performed. Descriptive statistics were applied together with deductive coding of qualitative data. ResultsA total of 104 hospital liaison nurses (66.7 %) and 52 GR professionals (33.3 %) participated. Respondents were reasonably satisfied with the current triage practice. Hospital liaison nurses valued their operational responsibility for triage. Geriatric rehabilitation professionals wanted active involvement in decision making and deemed hospital paramedic expertise sub-optimally applied. ‘Too little involvement’ of patients and families was felt by 50.0 % of the GR respondents versus 15.5 % of hospital respondents. The importance of half (47.8 %) of the triage items was rated differently between respondent groups. When discussing complex cases between sending and receiving professionals, views were felt as complementary. ConclusionsBoth sending and receiving professionals expressed moderate satisfaction with post-acute care decision making, whereas their views on triage assessments differed according to setting and role. The patients’ voice may be insufficiently heard in triage decisions. Shared expertise and a consensual approach can develop when triage consultation is facilitated by both hospitals and PAC facilities. This study offers ingredients to reach a multi-professional view on post-acute care decision making and referral to geriatric rehabilitation.

Hispidol Regulates Behavioral Responses to Ethanol through Modulation of BK Channels: A Novel Candidate for the Treatment of Alcohol Use Disorder.

Alcohol use disorder (AUD) is the most common substance use disorder and poses a significant global health challenge. Despite pharmacological advances, no single drug effectively treats all AUD patients. This study explores the protective potential of hispidol, a 6,4'-dihydroxyaurone, for AUD using the Caenorhabditis elegans model system. Our findings demonstrate that hispidol-fed worms exhibited more pronounced impairments in thrashes, locomotory speed, and bending amplitude, indicating that hispidol exacerbated the detrimental effects of acute ethanol exposure. However, hispidol significantly improved ethanol withdrawal behaviors, such as locomotory speed and chemotaxis performance. These beneficial effects were absent in slo-1 worms (the ortholog of mammalian α-subunit of BK channel) but were restored with the slo-1(+) or hslo(+) transgene, suggesting the involvement of BK channel activity. Additionally, hispidol increased fluorescence intensity and puncta in the motor neurons of slo-1::mCherry-tagged worms, indicating enhanced BK channel expression and clustering. Notably, hispidol did not alter internal ethanol concentrations, suggesting that its action is independent of ethanol metabolism. In the mouse models, hispidol treatment also demonstrated anxiolytic activity against ethanol withdrawal. Overall, these findings suggest hispidol as a promising candidate for targeting the BK channel in AUD treatment.

The Role of Government and Community Collaboration in the Implementation of Waste Management Policies in Palu City

Waste management is a crucial issue for the growing city of Palu. Collaboration between the government and the community is the key to effective and sustainable waste management policy implementation. This study aims to describe the collaborative role between the government and the community in the implementation of waste management policies in Palu City. The method used is descriptive, with data collection through observation, in-depth interviews with relevant parties, and analysis of waste management policy documents. The data obtained was analysed qualitatively to provide an overview of the dynamics of collaboration that occurred. The results showed that the Palu City government has played a role in formulating policies, providing waste management facilities and infrastructure, and building a supportive regulatory framework. The government also initiated waste management programmes such as waste banks and temporary disposal sites (TPS)). On the other hand, the role of the community is seen through active participation in these programmes, as well as involvement in waste reduction and recycling activities in their respective neighbourhoods. Nonetheless, challenges are still faced, including the low level of public awareness, the lack of supporting facilities, and inadequate law enforcement. This study concludes that good collaboration between the government and the community is essential in achieving more effective waste management in Palu City. Strengthening collaboration through education, improving facilities, and consistent law enforcement are needed so that waste management policies can be implemented optimally.

An Analysis of the Synergistic Impact of Leadership and Stakeholder Involvement: School-Based Quality Improvement Management

This research aims to analyze the synergistic impact between school leadership and stakeholder involvement in efforts to improve the quality of education at the Al Hijrah Integrated Islamic Middle School, Deli Serdang. A descriptive quantitative approach was used as a research method, and data was collected using questionnaires from respondents, namely the school principal and all school stakeholders. The results of the research show that school leadership that is synergistic and involves school stakeholders has a great influence on the management of improving school quality. Strong leadership and active stakeholder involvement have a significant positive impact on school-based quality improvement management. Visionary and learning-oriented leadership plays a key role in formulating a shared vision and strategy to improve the quality of education. The involvement of stakeholders, including teachers, parents, and the community, provides support, input, and active participation in the implementation of quality improvement programs. The synergy between effective leadership and involving stakeholders can create a collaborative and supportive learning environment. This leads to achieving the goals of better quality education, improving the quality of learning, and holistic development of student potential.

Cyber Pragmatic Analysis of Impoliteness Strategies Used by Detractors and Supporters of Presidential Candidates in Online Conflicts

This research aims to analyze the synergistic impact between school leadership and stakeholder involvement in efforts to improve the quality of education at the Al Hijrah Integrated Islamic Middle School, Deli Serdang. A descriptive quantitative approach was used as a research method, and data was collected using questionnaires from respondents, namely the school principal and all school stakeholders. The results of the research show that school leadership that is synergistic and involves school stakeholders has a great influence on the management of improving school quality. Strong leadership and active stakeholder involvement have a significant positive impact on school-based quality improvement management. Visionary and learning-oriented leadership plays a key role in formulating a shared vision and strategy to improve the quality of education. The involvement of stakeholders, including teachers, parents, and the community, provides support, input, and active participation in the implementation of quality improvement programs. The synergy between effective leadership and involving stakeholders can create a collaborative and supportive learning environment. This leads to achieving the goals of better quality education, improving the quality of learning, and holistic development of student potential.

Creating group work-integrated learning experiences for non-clinical health degrees: A practitioner reflection

Work-Integrated Learning (WIL) experiences, integral for equipping students with the skills and knowledge crucial for employment and success in their chosen careers, have traditionally been associated with accreditation requirements in professional programs. More recently, acknowledging the importance of WIL experiences in non-professional programs has grown. In this reflective paper, the experiences of the practitioner tasked with developing a new WIL capstone course for students in Health and Biomedical Science degrees are described. Grounded in social exchange theory, where interactions are viewed as exchanges aimed at maximising rewards while minimising costs, the intent was for student groups to engage with a range of authentic project experiences offered by industry, community, and academic staff (the WIL partners). Critical elements were the active involvement of a diverse array of partners and the importance of relationship building for the long-term sustainability of the project experiences. I discuss and reflect on the specific strategies employed to engage the WIL partners, inspiring them to collaborate and develop meaningful projects suitable for students pursuing various career paths. Additionally, I reflect on the invaluable experiences and feedback provided by our partners.

Социальная и личностная неопределенность как факторы социально-психологической устойчивости личности к вовлечению в террористическую организацию

Introduction. In the context of countering the ideology of terrorism, two main tasks are being solved: how to identify the most vulnerable social groups of the population to the perception of the ideas of terrorism and what preventive work should be carried out to weaken the effect of the ideology of terrorism. Theoretical analysis. It allows us to conclude that the degree of socio-psychological resistance of a person to involvement in a terrorist organization mainly depends on the recognition of the principles of national, political and religious doctrine by a person. The socio-psychological stability of a person to participate in terrorist acts is a personality quality consisting in a formed critical attitude towards terrorism, knowledge of the disastrous consequences of terrorism in society, and an active civic position, which includes rejection of terrorism. As a result, it can be argued that socio-personal uncertainty affects the socio-psychological stability of a person. Empirical analysis. Consideration of the problem of determining social and personal uncertainty on the socio-psychological stability of a person to involvement in terrorist activities has allowed us to conclude that socio-personal uncertainty affects the socio-psychological stability of a person. Conclusion social and personal uncertainty are a favorable environment for the formation of extremist views and justification of the ideology of violence, therefore it is necessary to introduce psychodiagnostic tools aimed at identifying the socio-psychological resistance of a person to involvement in terrorist activities.

Affective experiences from school physical education in children and adolescents

Affective exercise experiences comprise a spectrum of memories, capturing both unpleasant and pleasant episodes. These can be assessed using the Affective Exercise Experience Questionnaire (AFFEXX, Ekkekakis et al., 2021), which examines three separate aspects: 1) antecedent cognitive appraisals (e.g., “incompetence vs. competence”), 2) core affective exercise experiences (e.g., “displeasure vs. pleasure”), and 3) the hedonistic motivation (“antipathy vs. attraction”) to engage in exercise. A German version, AFFEXX-PEG, designed to assess the affective exercise experiences from physical education (PE) in school-aged students, was used to investigate the correlations with PE school grades (as reported by the participants) and extracurricular sports participation (self-reported as the number of days per week spent engaging in at least 60 minutes of sports activities). This study analysed data from 569 individuals (Mage = 14.62, SD ± 1.84; 52% female) across grades 5 to 13. Nearly one-third (29%) of students reported unpleasant core affective experiences from PE in school, and negative experiences correlated with lower PE grades, r(517) = .52, p < 0.001, 95% CI [.45, .58]. Less attraction or antipathy toward PE was associated with fewer days of sports outside of school, r(559) = .38, p < 0.001, 95% CI [.31, .45]. Multiple regression analysis with negative core affective experiences from PE as the criterion and the six cognitive appraisals as predictors, showed that these experiences were primarily influenced by students’ perceived incompetence (b = .49, p < 0.001; R² = .84, F(6, 500) = 436.52, p < 0.001) in PE. Given the empirical evidence on the correlation between affective experiences and exercise behaviours in adults (Rhodes & Kates, 2015), these findings highlight the potential role of fostering positive affective PE experiences. Such experiences may influence lifelong exercise behaviours, and early intervention may prevent the onset of an inactive lifestyle. A new study focuses on children’s (8-12 years) affective experiences from exercise and parent-child interactions, examining the influences of socioeconomic status, parental exercise involvement, and children’s self-perceived body esteem. Elementary school children will report their affective experiences on another, simplified version of the AFFEXX, while their parents will complete a survey on, for example, socioeconomic status and parental involvement in physical activity. By matching data from both surveys, the analysis will explore the relationships between household factors and children’s affective exercise experiences. The goal is to understand early negative affective exercise experiences, assess the impact of family structures, and offer strategies to promote exercise beyond regular school programs.

Review of foreign experience of professional adaptation of war veterans

Problem setting. After the end of the war, most of the veterans will be an economically active stratum of the population, who will need active support from the state when reintegrating into civilian life, but in return will be able to benefit the country by remaining active subjects of the national economy. The preservation and development of this potential is critically important both for the post-war recovery of Ukraine and for the establishment of social justice in relation to defenders. The study of foreign experiences is an important step in order to learn effective practices that can be adapted and applied to the Ukrainian context. Despite the fact that the experience of other countries does not always fully correspond to Ukrainian realities, it contains useful lessons and methods that can be modified to solve the specific challenges that Ukraine faces. Analysis of recent researches and publications. Such domestic researchers as V.P. Kokhan, A.S. Kolisnyk, O.V. Shapovalova, V.I. Sheverdina, T. Zakharina, V.K. Malolitneva, R.A. Jabrailov. M. Bazaeva studied foreign experience using the example of the USA. At the same time, there is no comprehensive overview of foreign policy regarding the support of veterans and their reintegration into civilian life in domestic works. Purpose of research is to carry out a general review of foreign experience in issues of support for veterans using the example of the USA, EU, Germany, France and Great Britain. Article`s main body. The article examines the issue of professional adaptation of veterans as a key element in the successful reintegration of military personnel into civilian life. It outlines the experiences of the United States, the European Union, Germany, France, and the United Kingdom to identify effective veteran support practices that could be adapted to the Ukrainian context. The focus is on the legal and organizational aspects of veteran policies, including legislative support and the involvement of both governmental and non-governmental organizations in the outlined area. The article concludes that the United States has a well-developed system of veteran support, primarily driven by the Department of Veterans Affairs (VA). Special attention is given to the functioning of the U.S. Court of Appeals for Veterans Claims (CAVC). It is suggested that the establishment of a similar specialized judicial body could be an important step for Ukraine to effectively protect veterans’ rights in the post-war period. The article highlights the absence of unified legislation on veterans within the European Union. Nevertheless, it emphasizes the role of pan-European non-governmental organizations in this field, such as the European Confederation of Veterans. The legal and institutional framework for veteran policies in specific EU member states, particularly Germany and France, is also discussed. Special attention is given to the experience of the United Kingdom, which aspires to have the most advanced veteran support system. It is noted that the strategic approach to veteran policy, particularly through the Veterans’ Strategy Action Plan 2022-2024, provides long-term legal certainty for veterans and enhances the effectiveness of state policy. Conclusions and prospects for the development. The article underlines that professional adaptation of veterans is a critical precondition for successful post-war recovery in Ukraine and the preservation of veterans’ economic activity. The use of foreign experience, particularly the creation of specialized judicial bodies, the development of national veteran support strategies, and the active involvement of non-governmental organizations, could become a subject of further discussion aimed at finding the optimal path for building an effective veteran support system in Ukraine.

Abstract A107: Be Part of the Cure Clinical Trials Campaign: Koreans, Hispanic/Latino/a/e/x, and Black/African Americans living in Los Angeles County

Abstract Background. There is negative perception and lack of participation in clinical trials among Koreans, Hispanic/Latino/a/e/x, and Black/African Americans living in Los Angeles County, which may be attributed to cultural beliefs, language barriers, historical mistrust of medical research, and lack of awareness about the benefits of participation. Without representation from diverse groups, there may be missed opportunities to develop personalized treatment approaches tailored to specific genetic, cultural, and lifestyle factors. Methods. Cedars Sinai Cancer Community Outreach and Engagment (COE) developed a multi-level approach to increase representation of minority populations in clinical trials. With active Community Advisory Board involvement in the development and implementation, a culturally sensitive clinical trials awareness campaign, “Be Part of the Cure”, was developed to offer in-language cancer information, education on clinical trials, and navigation through the cancer care continuum. To support patients and facilitate access to trials, COE has developed bi-directional engagement between CCSC physicians, nurses and Clinical Trials Office representatives, FQHCs, and community and faith-based organizations to ensure a seamless navigation process to care. Additionally, our multicultural and multilingual COE staff have trained Community Health Workers and navigators to expand our outreach efforts and effectively engage our target communities. Results. In total, COE has facilitated 7 health education workshops and attended 3 community outreach events with 501 people educated (37% or 184 Black/African American; 25% or 123 Asians; 17% or 87 Hispanic/Latinx; and 21% or 107 White). Pre/post-tests administered to 73 Koreans during health education workshops showed significant increase in positive perception on clinical trials from 57% to 95%. Korean (n=9) cancer patients have expressed interest in clinical trials, and 1 have been enrolled in Neoadjuvant HER2-Targeted Therapy and Immunotherapy with Pembrolizumab clinical trial. Among Hispanic/Latinx/a/o community, 1 clinical trials health awareness workshop was convened with clinicians who presented to promotores, patients, caregivers, survivors and community members. There were 25 people who completed the pre/post test. There was an increase in positive perception on clinical trials from 52% to 100%, willingness to participate from 60% to 96%, and likelihood of encouraging others to participate from 60% to 96%. In the Black/African American community, 1 clinical trials health awareness workshop was also convened. Among attendees, 21 people completed Pre/Post Test and positive perception on clincal trials increased from 47% to 85%, willingness to participate from 43% to 81%, and likehood on encouraging others to participate from 52% to 81%. Conclusion. Efforts to increase diversity and inclusion in clinical trials should focus on culturally sensitive recruitment strategies, language accessibility, community engagement, and building trust between researchers and communities. Citation Format: Ghecemy Lopez, Dong Hee Kim, Zul Surani, Lourdes Barajas. Be Part of the Cure Clinical Trials Campaign: Koreans, Hispanic/Latino/a/e/x, and Black/African Americans living in Los Angeles County [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A107.

Study of Anxiety Among Older People in Kazakhstan and Factors Affecting This Indicator

<b>Aim:</b> The purpose of this research was to study of anxiety among older people in Kazakhstan and factors affecting this indicator.<br /> <b>Methods:</b> A cross-sectional survey was conducted with 221 randomly selected elderly people from different regions of Kazakhstan. The survey covered questions of socio-demographic type and also used the GAD-7 (Generalized Anxiety Disorder-7).<br /> <b>Results:</b> The majority of participants showed low levels of anxiety on the test. Nevertheless, a significant proportion of older adults experienced mild and moderate anxiety, accounting for 33% and 23.1%, respectively. The analysis showed that age (OR = 0,852, 95% CI: 0,779-0,931, p < 0,001), gender (OR = 8,167, 95% CI: 3,232-20,642, p < 0,001), level of education (OR=9,928, CI 95%: 3,760 - 26,212, p < 0,001) and living conditions (OR=0,167, 95% CI: 0,060-0,467, p = 0,001) have a statistically significant impact on the anxiety level of this population group.<br /> <b>Conclusion:</b><b> </b>The results of the analysis confirm the importance of developing and implementing a set of measures aimed at improving the quality of life of older people, taking into account the individual characteristics and needs of each person. The following measures can be suggested to improve the quality of life of older persons: organize social activity and community involvement programs through clubs and activities; establish accessible health and social service centers where older persons can receive qualified care; use technology, such as mobile applications and smart devices, to facilitate daily life, including telemedicine and home-based services.

Sustainability of Quality Management by Implementing Data Mining to Predict Academic Achievement

This research aims to predict the academic achievement of Pamulang University students using Educational Data Mining (EDM) techniques. With the increasing number of students and the complexity of academic data, it is important to apply methods that can analyze and predict learning outcomes to improve learning strategies and academic support. This study collected data from various sources, including course grades, attendance, and participation in extracurricular activities. The collected data is then analyzed using EDM techniques such as decision trees, neural networks, and support vector machines to identify patterns and factors that contribute to student academic achievement. The results of the analysis show that factors such as attendance, involvement in campus activities, and previous test scores have a significant influence on academic achievement. This research provides valuable insights for the development of targeted interventions, with the aim of improving academic outcomes and facilitating more effective learning strategies at Pamulang University. These findings also offer contributions to further research in the field of EDM and its application in higher education contexts.