This paper addresses the trade-off between ride comfort and road-holding capability of a quarter-car semi-active suspension system, collaborated by an active aerodynamic surface (AAS), using an optimal control policy. The semi-active suspension system is more practical to implement due to its low energy consumption than the active suspension system while significantly improving ride comfort. First, a model of the two-DOF quarter-car semi-active suspension in the presence of an active airfoil with two weighting sets based on ride comfort and road-holding preferences is presented. Then, a comprehensive comparative study of the improved target performance indices with various suspension systems is performed to evaluate the proposed suspension performance. Time-domain and frequency-domain analyses are conducted in MATLAB® (R2024a). From the time-domain analysis, the total performance measure is enhanced by about 50% and 35 to 45%, respectively, compared to passive and active suspension systems. The results demonstrate that a semi-active suspension system with an active aerodynamic control surface simultaneously improves the conflicting target parameters of passenger comfort and road holding. Utilizing the aerodynamic effect, the proposed system enhances the vehicle’s dynamic stability and passenger comfort compared to other suspension systems.