Tobacco smoking among adolescents is still frequent and stalling in the last decades, so the main purpose of this research is to know if the COVID-19 pandemic had an impact on adolescents' perceptions regarding smoking. We investigated: 1) the prevalence of active cigarette smoking; 2) if smoking of parents and friends and school environment influences the choice to smoke; 3) if the students capture the presence of images of smoking in films; 4) the level of concern of the younger people regarding the association between Covid-19 disease and smoke. 719 students (65% boys, aged 13-19 years, from the high school, technical and professional institutes) filled an anonymous questionnaire (31-item), during Covid-lockdown. The students have been subdivided into the following categories: daily smokers (12.8%), occasional (30.3%), former (8.8%) and never smokers (48.1%). 52% of students have smoked at least once (n.s. for gender). Interestingly, over time the probability of starting to smoke decreases (fig1). Furthermore, the students who start smoking early tend to smoke daily (r=-0.13;p < 0.01) and more cigarettes (r=-0.30; p < 0.01). 83% of students start smoking out of curiosity and a spirit of adventure, consuming 1 to 4 cigarettes daily. Moreover 30% of them would want to quit but failed; 27% never thought about it; while 44% report that they will quit smoking in a few years. 59% consume manufactured cigarettes, 36% smoke rolling tobacco; 3% use HNB and 2% e-cigarettes. The type of cigarettes considered less harmful are electronic cigarettes. 68% of the student smokers have in turn someone in the family who smokes, on the contrary only 37.5% of non-smoking students have parent smokers. Considering only the students who smoked at least once, 65% replied that someone among friends smoke, while only 4% of no-smokers have smoking friends. Finally, the adolescents attending professional institutes smoke daily and more cigarettes (F (2, 368)=5.32; p<0.05) compared to the other. Moreover, it emerged that 48% do not pay attention to smoking scenes in the movies. About the coronavirus epidemic, 80% reported a upper-middle concern and 84% think that is very dangerous for smokers, while 76,3% consider that the respiratory symptoms of smokers Covid-19 patients could have a worse outcome and that being a smoker can become very dangerous for the clinical complications that can occur (84%). These data, even more meaningful during COVID-19 pandemic, highlight the importance and the need of primary prevention as well as of suitable secondary prevention programs.