Active Avoidance Research Articles

White-tailed deer detection rates increase when coyotes are present.

Predator species can indirectly affect prey species through the cost of anti-predator behavior responses, which may involve shifts in occupancy, space use, or movement. Quantifying the various strategies implemented by prey species to avoid adverse interactions with predators can lead to a better understanding of potential population-level repercussions. Therefore, the purpose of this study was to examine predator-prey interactions by quantifying the effect of predator species presence on detection rates of prey species, using coyotes (Canis latrans) and white-tailed deer (Odocoileus virginianus) in Central Appalachian forests of the eastern United States as a model predator-prey system. To test two competing hypotheses related to interspecific interactions, we modeled species detections from 319 camera traps with a two-species occupancy model that incorporated a continuous-time detection process. We found that white-tailed deer occupancy was independent of coyote occupancy, but white-tailed deer were more frequently detectable and had greater detection intensity at sites where coyotes were present, regardless of vegetation-related covariates. In addition, white-tailed deer detection rates at sites with coyotes were highest when presumed forage availability was relatively low. These findings suggest that white-tailed deer may be exhibiting an active avoidance behavioral response to predators by increasing movement rates when coyotes are present in an area, perhaps due to reactive evasive maneuvers and/or proactive attempts to reduce adverse encounters with them. Concurrently, coyotes could be occupying sites with higher white-tailed deer densities. Because white-tailed deer did not exhibit significant shifts in daily activity patterns based on coyote occupancy, we further suggest that white-tailed deer in our study system generally do not use temporal partitioning as their primary strategy for avoiding encounters with coyotes. Overall, our study implements a recently developed analytical approach for modeling multi-species occupancy from camera traps and provides novel ecological insight into the complex relationships between predator and prey species.

Research on robustness of intelligent vehicle longitudinal active collision avoidance system based on equivalent external interference

The rate of fatal traffic accidents caused by sudden risks such as pedestrians crossing the road in violation of regulations and goods falling in front of the vehicles has remained high under the complex dynamic environment. The appearance of sudden obstacles/pedestrians will indirectly trigger sudden changes in sensor signals and control signals, and cause the drivers’ improper driving behaviors. At the same time, the parameter perturbation of the vehicle itself and the sensor noise and other direct disturbances will also put forward high requirements for the robust performance of the vehicle braking system controller. Traditional control methods are difficult to ensure the robust stability required by the vehicle braking system in the actual driving process under sudden emergency conditions. In order to improve the braking control performance and robust performance of the active collision avoidance system under sudden emergency conditions under the influence of its own parameter perturbation, sensor perturbation and other perturbations, this manuscript analyzes the accident risk characteristics of sudden emergency conditions, and establishes an equivalent virtual external force interference model [Formula: see text]. Considering the virtual external force interference model, self-driving parameter perturbation and sensor perturbation, we adopt the [Formula: see text] control theory-design brake controller. Under different perturbation conditions the [Formula: see text] controller, PID controller, and [Formula: see text] controller are simulated and compared. The results show that the [Formula: see text] controller can effectively suppress sudden emergency conditions under parameter uncertainty and external sensor noise interference compared with the PID controller and the [Formula: see text] controller, realizing emergency braking and collision avoidance, and having better closed-loop robustness.

Health Equity in the Veterans Health Administration From Veterans’ Perspectives by Race and Sex

Advancing equitable patient-centered care in the Veterans Health Administration (VHA) requires understanding the differential experiences of unique patient groups. To inform a comprehensive strategy for improving VHA health equity through the comparative qualitative analysis of care experiences at the VHA among veterans of Black and White race and male and female sex. This qualitative study used a technique termed freelisting, an anthropologic technique eliciting responses in list form, at an urban academic VHA medical center from August 2, 2021, to February 9, 2022. Participants included veterans with chronic hypertension. The length of individual lists, item order in those lists, and item frequency across lists were used to calculate a salience score for each item, allowing comparison of salient words and topics within and across different groups. Participants were asked about current perceptions of VHA care, challenges in the past year, virtual care, suggestions for change, and experiences of racism. Data were analyzed from February 10 through September 30, 2022. The Smith salience index, which measures the frequency and rank of each word or phrase, was calculated for each group. Responses from 49 veterans (12 Black men, 12 Black women, 12 White men, and 13 White women) were compared by race (24 Black and 25 White) and sex (24 men and 25 women). The mean (SD) age was 64.5 (9.2) years. Some positive items were salient across race and sex, including "good medical care" and telehealth as a "comfortable/great option," as were some negative items, including "long waits/delays in getting care," "transportation/traffic challenges," and "anxiety/stress/fear." Reporting "no impact" of racism on experiences of VHA health care was salient across race and sex; however, reports of race-related unprofessional treatment and active avoidance of race-related conflict differed by race (present among Black and not White participants). Experiences of interpersonal interactions also diverged. "Impersonal/cursory" telehealth experiences and the need for "more personal/attentive" care were salient among women and Black participants, but not men or White participants, who associated VHA care with courtesy and respect. In this qualitative freelist study of veteran experiences, divergent experiences of interpersonal care by race and sex provided insights for improving equitable, patient-centered VHA care. Future research and interventions could focus on identifying differences across broader categories both within and beyond race and sex and bolstering efforts to improve respect and personalized care to diverse veteran populations.

The Active Place Avoidance (APA) Test, an Effective, Versatile and Repeatable Spatial Learning Task for Mice.

Hippocampus-dependent spatial learning in rodents has been tested using a variety of methods. These include the Morris water maze (MWM), Y-maze, and novel object location (NOL) tasks. More recently, the active place avoidance (APA) task has been developed as an alternative to these more traditional approaches. In the APA task, mice must use spatial cues placed around a rotating arena to avoid a stationary shock zone. Due to the multiple parameters that can be adjusted, the APA task has been demonstrated to be a very versatile approach. It lends itself to being used longitudinally and repeatedly for the same cohort of mice. Here, we provide a detailed protocol to successfully conduct the APA task. We also highlight alternative APA approaches that can be used to examine different components of spatial learning. We describe the data collection and analysis processes. Critical steps during the APA task are discussed to increase the likelihood of successfully conducting the test. The APA task has several advantages over more traditional spatial navigation tests. It is appropriate to use with aged mice or those with disease phenotypes such as Alzheimer's disease. The complexity of the task can be easily altered, allowing a wide range of mouse strains to be tested. Further, the APA task is suitable for testing animals that have undergone surgery or experimental interventions that may have affected motor or neural function, such as stroke or traumatic brain injury.

Design of Human-Machine Integration System to Meet Diverse Interactive Tasks

A flexible production model in which humans and robots collaborate has become an urgent need for industrial production. Therefore, research on human-machine integration systems has received more and more attention in recent years. Human-computer interaction is widely used in industrial production and entertainment life, such as industrial control, VR games, etc. In this article, we designed and implemented a human-machine fusion system that meets different interactive tasks. Human movement estimation and robot interactive control are the key technologies. First, we propose a human posture solution method based on information fusion of multiple cameras and inertial measurement units. This method constructs an optimization problem, fuses the 2D joint detection information under multiple cameras and the measurement information of the worn inertial measurement unit, and optimizes the estimation of human kinematic posture, which improves the problems of incomplete posture information and sensitivity to noise under a single sensor. Therefore, this method improves the accuracy of pose estimation. Secondly, combining the kinematic characteristics of the robot and the characteristics of human-computer interaction, we designed a robot control strategy based on target point tracking and model predictive control, so that the robot can adapt to dynamic environments and different interaction needs by adjusting control parameters. At the same time, our design ensures the safety of robots and operators. Finally, we conducted human-computer interaction experiments such as action following, item delivery, and active obstacle avoidance. The experimental results show the effectiveness and reliability of the designed robot interaction system in a human-machine fusion environment.

Heed guidance from new OCR letter for handling AAOs/no contact orders

The Office for Civil Rights has published its first determination letter of 2024 on its website (bit.ly/3SpW9Ol). Although not the sole focus of the determination, the letter and accompanying Title IX analysis offer extremely valuable guidance on how to issue and monitor active avoidance orders/no contact orders in compliance with Title IX.

Lateralized Active Avoidance Learning and Memory to Ang II and Losartan Microinjected into Amygdala in Rats Depression Model

Depression is a widespread socially significant disease. Studies aiming to reveal the pathogenesis of depression have lasted for decades, but the specific mechanisms remain unclear. Olfactory bulbectomy (OBX) in rats provides a well-validated animal model of depression and Alzheimer's disease. The aim is to evaluate the involvement of Ang II and AT1 receptors in learning and memory after unilateral infusion of Ang II and losartan (specific AT1 antagonist) into CeA (central nucleus of the amygdala) in rats with a model of depression (bilateral olfactory bulbectomy, OBX). The effects of Ang II and losartan infused into CeA on the avoidance performance in OBX rats using the active avoidance (shuttle box) test were investigated. A stereotaxic technique was used for bilateral implantation of guide cannulae into CeA. Fourteen days after OBX, Ang II, or losartan were microinjected unilaterally into CeA of rats with depressive-like behaviour. For the first time it was found that Ang II infused into the left CeA impaired learning and memory, while losartan infused into the left CeA significantly improved these processes and prevented the memory deficits induced by the bulbectomy. The data suggest an involvement of amygdala Ang II and AT1 receptors in learning and memory of rats and a differential distribution of the AT1 receptors in the left and right central nucleus of the amygdala in rats with a model of depression.

Evidence of active oviposition avoidance to systemically applied imidacloprid in the Colorado potato beetle.

Agricultural pests can develop behavioral resistance to insecticides by choosing to feed or oviposit on insecticide-free hosts. As young larvae have relatively low mobility, oviposition preferences from female adults may play a critical role in shaping the evolutionary trajectory of pest populations. While oviposition avoidance of insecticide-treated hosts was found in different agriculture pests, it remains unclear whether female adults actively choose to occupy insecticide-free hosts. To address this question, we investigated feeding and oviposition preferences between imidacloprid-treated and imidacloprid-free plants in the Colorado potato beetle, Leptinotarsa decemlineata Say, a major potato pest. We performed behavioral choice assays on two strains that differed in both fecundity and insecticide resistance. We found that one strain preferred to feed on the insecticide-free plants and that this preference is not innate. Meanwhile, the other strain chose plants for feeding and oviposition randomly. Further analyses of the moving patterns of the beetles suggested that the oviposition preference in the first strain is likely due to active learning.

Intersection collision risk evaluation and active collision avoidance strategies for autonomous vehicles

In order to ensure that the autonomous vehicle can predict and taking actions to avoid the collision in time when facing the obstacles with intersection collision risk, an intersection collision risk prediction system is proposed in this paper, and two kinds of active obstacle avoidance strategies are designed according to the system: braking strategy and steering strategy. The position information of the obstacle is predicted by Fractional extended Kalman filter, the collision risk rate is determined by the time difference between the vehicle and the obstacle through the intersection point, and a neural network is trained to quickly give the collision risk of the vehicle and the obstacle. Braking strategy and steering strategy are formulated according to collision risk, the braking deceleration and Sigmoid path parameters are given. Finally, the simulation results of PreScan and MATLAB show that the collision risk prediction system can accurately predict the collision between vehicles and obstacles, the braking and steering strategies can effectively avoid the collision.

Anhedonia influences threat avoidance and relief: A conceptual replication

Active threat avoidance is an adaptive coping strategy but can evolve into maladaptive behavior patterns when it is disproportionate to an actual threat. While excessive and persistent avoidance, as often seen in anxiety-related disorders, have been investigated extensively, it is presently unclear under what circumstances insufficient avoidance might occur in the presence of a genuine threat. We hypothesized that anhedonia, the reduced ability to experience pleasure, might undermine the relief experience after successful threat avoidance and thus reduce future active avoidance responses. Using an established avoidance learning paradigm, we examined the relationship between anhedonia, relief, and active avoidance responses. Forty participants learned that two threat cues signaled electrical stimulation and they could click a button during cue presentations to prevent electrical stimulation from occurring. While clicking the button worked for one threat cue, it did not work for the other one. After several repetitions, button effectiveness was reversed. Another safety cue that never signaled electrical stimulation was presented intermixed with the two threat cues. Every time there was an omission of electrical stimulation, self-reported relief was measured. We found that participants who scored higher on anhedonia experienced weaker relief during all outcome omissions. Behaviorally, at the early stage of each phase, participants who scored higher on anhedonia executed fewer avoidance actions, specifically for the threat cue that signaled avoidable electrical stimulation. Relief induced by threat omission is a pleasant experience, which trait anhedonia seems to impair. This attenuation of relief might reduce the reinforcement of future adaptive avoidance behaviors.

The role of the GABAergic cells of the median raphe region in reinforcement-based learning

Learning and memory are important in everyday life as well as in pathological conditions. The median raphe region (MRR) contributes to memory formation; however, its precise role and the neurotransmitters involved have yet to be elucidated. To address this issue, we stimulated the MRR neurons of mice by chemogenetic technique and studied them in the operant conditioning and active avoidance tests. The virus carrier infected a variety of neuron types including both GABAergic and glutamatergic ones. Behavior was not influenced by stimulation. We hypothesize that the lack of effect was due to opposing effects exerted via GABAergic and glutamatergic neurons. Therefore, next we used VGAT-Cre mice that allowed the specific manipulation of MRR-GABAergic neurons. The stimulation did not affect behavior in the learning phase of the operant conditioning task, but increased reward preference and total responses when operant contingencies were reversed. The enhanced responsiveness might be a proclivity to impulsive behavior. Stimulation facilitated learning in the active avoidance test but did not affect reversal learning in this paradigm. Our findings suggest that MRR-GABAergic neurons are involved in both learning and reversal learning, but the type of learning that is affected depends on the task.

Fracture-Induced Effects on the Onset & Progression of Alzheimer’s Disease

Alzheimer’s disease and related dementias (AD/ADRD) are multifactorial, highly heterogeneous, and complex age-dependent disorders that severely affect memory and cognitive function, impacting nearly 35.6 million people worldwide. In the elderly, dementia increases the risk of falls and fractures by 2-3 times, due in part to neurovascular instability, low bone mineral density due to pre-existing osteoporosis, and poor musculature supporting joints due to cachexia and/or sarcopenia.
 While the occurrence of fractures due to AD/ADRD is well documented, an association between fractures and AD/ADRD onset or progression is underappreciated and warrants additional investigation. We aim to investigate the mechanistic actions underlying fracture healing as a precipitating event for AD/ADRD pathogenesis.
 Four-month-old, male, 5xFAD (AD model) and wild-type control (C57BL/6) mice were divided into 2 groups: surgically induced femoral fractures and uninjured mice. Prior to surgery mice underwent baseline AD behavior testing including: spontaneous alternation in the y-maze, light-dark exploration in the open field, and active place avoidance assays. Mice are undergoing weekly x-ray imaging to monitor fracture healing progression and longitudinal AD behavior testing. 22 weeks post-surgery mice will be euthanized, and femurs and brains collected. Femurs will undergo uCT imaging and histological assessment of bone healing and immunohistochemical assessment of inflammatory markers. Brains will be processed for histology and neuroinflammatory marker analysis, including Aβ plaque deposition, tau tangles, neuronal survival, neurogenesis, and activation/proliferation of microglia and astrocytes.
 At the conclusion of the study, we expect to see an increase in neuroinflammatory markers and delayed fracture healing in the experimental 5xFAD group. We anticipate that compared to uninjured controls, femoral fracture results in cognitive decline, Aβaccumulation/neurodegeneration, increases in neuroinflammation, and vascular impairment. We anticipate finding a correlation between fracture and worsened AD outcomes. By uncovering the mechanisms underlying this relationship, we hope to guide future studies to develop more robust therapeutics.

Lateral hypothalamic glutamatergic inputs to VTA glutamatergic neurons mediate prioritization of innate defensive behavior over feeding

The lateral hypothalamus (LH) is involved in feeding behavior and defense responses by interacting with different brain structures, including the Ventral Tegmental Area (VTA). Emerging evidence indicates that LH-glutamatergic neurons infrequently synapse on VTA-dopamine neurons but preferentially establish multiple synapses on VTA-glutamatergic neurons. Here, we demonstrated that LH-glutamatergic inputs to VTA promoted active avoidance, long-term aversion, and escape attempts. By testing feeding in the presence of a predator, we observed that ongoing feeding was decreased, and that this predator-induced decrease in feeding was abolished by photoinhibition of the LH-glutamatergic inputs to VTA. By VTA specific neuronal ablation, we established that predator-induced decreases in feeding were mediated by VTA-glutamatergic neurons but not by dopamine or GABA neurons. Thus, we provided evidence for an unanticipated neuronal circuitry between LH-glutamatergic inputs to VTA-glutamatergic neurons that plays a role in prioritizing escape, and in the switch from feeding to escape in mice.

Perineuronal nets are associated with decision making under conditions of uncertainty in female but not male mice

Biological sex influences decision-making processes in significant ways, differentiating the responses animals choose when faced with a range of stimuli. The neurobiological underpinnings that dictate sex differences in decision-making tasks remains an important open question, yet single-sex studies of males form most studies in behavioural neuroscience. Here we used female and male BALB/c mice on two spatial learning and memory tasks and examined the expression of perineuronal nets (PNNs) and parvalbumin interneurons (PV) in regions correlated with spatial memory. Mice underwent the aversive active place avoidance (APA) task or the appetitive trial-unique nonmatching-to-location (TUNL) touchscreen task. Mice in the APA cohort learnt to avoid the foot-shock and no differences were observed on key measures of the task nor in the number and intensity of PNNs and PV. On the delay but not separation manipulation in the TUNL task, females received more incorrect trials and less correct trials compared to males. Furthermore, females in this cohort exhibited higher intensity PNNs and PV cells in the agranular and granular retrosplenial cortex, compared to males. These data show that female and male mice perform similarly on spatial learning tasks. However, sex differences in neural circuitry may underly differences in making decisions under conditions of uncertainty on an appetitive task. These data emphasise the importance of using mice of both sexes in studies of decision-making neuroscience.

Neuroprotective effect of the RNS60 in a mouse model of transient focal cerebral ischemia.

Stroke is a major cause of death, disability, and public health problems. Its intervention is limited to early treatment with thrombolytics and/or endovascular clot removal with mechanical thrombectomy without any available subacute or chronic neuroprotective treatments. RNS60 has reduced neuroinflammation and increased neuronal survival in several animal models of neurodegeneration and trauma. The aim here was to evaluate whether RNS60 protects the brain and cognitive function in a mouse stroke model. Male C57BL/6J mice were subjected to sham or ischemic stroke surgery using 60-minute transient middle cerebral artery occlusion (tMCAo). In each group, mice received blinded daily administrations of RNS60 or control fluids (PNS60 or normal saline [NS]), beginning 2 hours after surgery over 13 days. Multiple neurobehavioral tests were conducted (Neurological Severity Score [mNSS], Novel Object Recognition [NOR], Active Place Avoidance [APA], and the Conflict Variant of APA [APAc]). On day 14, cortical microvascular perfusion (MVP) was measured, then brains were removed and infarct volume, immunofluorescence of amyloid beta (Aβ), neuronal density, microglial activation, and white matter damage/myelination were measured. SPSS was used for analysis (e.g., ANOVA for parametric data; Kruskal Wallis for non-parametric data; with post-hoc analysis). Thirteen days of treatment with RNS60 reduced brain infarction, amyloid pathology, neuronal death, microglial activation, white matter damage, and increased MVP. RNS60 reduced brain pathology and resulted in behavioral improvements in stroke compared to sham surgery mice (increased memory-learning in NOR and APA, improved cognitive flexibility in APAc). RNS60-treated mice exhibit significant protection of brain tissue and improved neurobehavioral functioning after tMCAo-stroke. Additional work is required to determine mechanisms, time-window of dosing, and multiple dosing volumes durations to support clinical stroke research.

Old Age Exacerbates White Matter Neuroinflammation and Cognitive Deficits Following Closed-Head Injury, Particularly in Female Mice.

The increasing incidence of traumatic brain injury (TBI) among older adults, particularly mild injuries from falls, underscores the need to investigate age-related outcomes and potential sex differences in response to TBI. Although previous research has defined an aging-TBI signature (heightened glial responses and cognitive impairment) in open-skull moderate-to-severe TBI models, it is unknown whether this signature is also present in mild closed-head injuries (CHIs). This study explores the influences of age and sex on recovery in a mouse CHI model induced by an electromagnetic impactor device in 4-month-old and 18-month-old C57BL/6 mice. We assessed the righting reflex, body weight, behavior (radial arm water maze and active avoidance), and inflammation (GFAP, IBA1, CD45) in the neocortex, corpus callosum, and hippocampus. We observed that aged female mice exhibited more severe TBI-induced cognitive deficits. In addition, a more pronounced reactive neuroinflammatory response with age was noted within white matter regions. Conversely, gray matter regions in aged animals either showed no enhanced pathological changes in response to injury or the aged mice displayed hyporesponsive glia and signs of dystrophic glial degeneration that were not evident in their younger counterparts following CHI. These findings suggest that aging influences CHI outcomes, partially reflecting the aging-TBI signature seen in more severe injuries in white matter, while a distinct aging and mild-TBI signature was identified in gray matter. The heightened vulnerability of females to the combined effects of age and mild CHI establishes a foundation for further investigation into the mechanisms underlying the sexually dimorphic response in aging females.

Research on Active Obstacle Avoidance in Seismic Acquisition using Compressed Sensing and deep learning Reconstruction Technology

Research on Active Obstacle Avoidance in Seismic Acquisition using Compressed Sensing and deep learning Reconstruction Technology

Ethological study of the state of anxiety in rats with chronic nickel nitrate poisoning on the background of experimental atherosclerosis

The purpose of this study was to study the effect of chronic poisoning with nickel nitrate in experimental atherosclerosis on the state of anxiety in the «elevated plus maze» test. The experiments were carried out on 50 white non-linear male rats. The model of atherosclerosis was created according to I.V. Savitsky et al. (2016), which is based on the polyetiological theory of the development of the disease. After modeling atherosclerosis, poisoning with nickel nitrate was carried out through the drinking water for 60 days at a dose of 2 mg/kg. The results showed that the behavioral disturbances that occurred after the modeling of atherosclerosis were aggravated after poisoning with nickel nitrate. In particular, in the «elevated plus maze» test, adequate parameters visually reflecting the state of anxiety were manifested in active avoidance of the open space of the maze, in a decrease in the number of vertical stands, in a decrease in the number of hanging from open sleeves, in a decrease in the number of looks from closed sleeves, as well as in a decrease of grooming number with a corresponding increase in its duration. Maximum disturbances were observed two months after exposure to nickel nitrate. The obtained data show a toxic neurotropic effect of chronic intoxication with nickel nitrate in experimental atherosclerosis and highlight the necessity of creating efficient remediation methods.

Toxicity of products of thermal oxidative degradation of nitrogen-containing building polymer materials

Introduction. In the event of fires in residential premises in which nitrogen-containing thermal insulation materials (foam rubber, polyisocyanurate foam) are used, the victims will be exposed to toxic thermal degradation products. Data on long-term disorders caused by intoxication by thermal degradation products of these materials could not be found in the available literature. The aim of the study was to assess the toxicity of the products of thermal oxidative degradation of nitrogen-containing thermal insulation materials, both in the early and long-term post-intoxication period. 
 Material and methods. Static inhalation intoxication of rats with products of thermooxidative destruction of polyfoam and polyisocyanurate foam (at a concentration of 0,8HLC50) was simulated. The concentration of carboxyhemoglobin in the blood of rats, indicators of vital functions were determined immediately before and on days 1, 7 and 28 after exposure. To assess learning disabilities in rats, a conditioned reflex of active avoidance by swimming was developed. To assess spatial memory in rats, the method of developing and reproducing the conditioned reflex of searching for food was used.
 Results and discussion. The intoxication of rats with products of thermooxidative destruction of the studied materials of moderate severity was simulated. Violations of the functions of the respiratory and cardiovascular system of rats in the early (7 days) and long-term (28 days) post-intoxication period were not detected. In the long-term (28 days) post-intoxication period, an increase in the duration of the latent period of active avoidance by swimming of rats was determined (compared with the control), an increase in the number of spatial memory errors in rats and the time of testing (compared with the control) was revealed.
 Limitation of the study. Limitations are due to the methodology of the research being conducted. A quantitative analysis of only some gaseous products of thermal oxidative destruction was perfomed.
 Conclusion. It was found that intoxication of rats with products of thermooxidative destruction of foam rubber and foam polyiysocyanurate (at a concentration of 0,8HLC50) led to impaired learning and spatial memory of rats in the long-term post-intoxication period.

Research on the Hydraulic Characteristics of Active Ship Collision Avoidance Devices for Hydrodynamic High-Energy Beam Bridges under Relatively Optimum Deployment Conditions

To address the limitations of existing bridge anti-ship collision devices, which cannot protect both ships and bridges, this study introduced a hydraulic high-energy beam for inland navigation safety. Using a bridge as the technical basis and a typical ship in a navigable river section as the research object, the reasonable deployment angle of the device was investigated and the optimal jet ratio of the device R (the ratio of the high-energy beam jet to the mainstream flow velocity) was clarified through combined numerical simulations and a generalized model test. The ship’s motion response state was subsequently validated when the device was reasonably deployed. The results showed that the reasonable deployment angles of the device were 0°, 15°, and 30°. R = 4 served as the optimal jet ratio. Furthermore, the peak value of turbulence intensity in the Y direction was noticeably smaller than in the other three groups, with a stable change. The coordinate error of the key positions in the numerical simulations and generalized model test of ship motion response was less than 10%, the maximum error of the transverse coordinate of the deflection position was −9.8% and the maximum error of the longitudinal coordinate was −7.0%. The maximum error of the transverse coordinate of the maximum deflection position was −6.8% and the maximum error of the longitudinal coordinate was 3.7%. The numerical simulations and generalized model tests of ship motion response fit well.