In this study, volumetric, viscometric, and refraction properties of binary 4-diethylamino-2-butanol (DEAB) and water mixture were comprehensively investigated over an entire range of amine concentration and a temperature range of 298.15-343.15 K. In addition to typical density, viscosity, refractive index, and their excess properties, the associated properties (including partial molar volume, apparent partial molar volume, partial molar volume and apparent partial molar volume at infinite dilution, thermal expansion coefficient, excess thermal expansion coefficient, Gibbs free energy, enthalpy, entropy, excess Gibbs free energy, and excess entropy for activation of viscous flow, molar polarizability, and molar free volume) were comprehensively considered. The obtained excess properties revealed that there was a strong contraction of liquid mixture through intermolecular interaction and/or preference molecular packing. Also, Gibbs free energy for activation of viscous flow was a key parameter affecting liquid viscosity. It was suggested that refractive index should be considered with density for a molar polarizability and a free molar volume for CO2 physical solubility. Additionally, the Redlich-Kister equation was very effective for correlating the studied excess physical properties.