Activated Hageman Factor Research Articles

Surface activation of plasma clotting: a function of Hageman factor.

Summary1. Asbestos treatment of plasma produced activation (clotting-time acceleration) in normal and AHF, PTC, proconvertin, prothrombin, proaccelerin and Stuart deficient plasmas. Hageman deficient plasma was not activated by comparable treatment. 2. Purified Hageman factor preparations from normal sera simulated activation, whereas preparations from sera of Hageman trait patients were inactive in the same test system. 3. The phenomenon of surface activation resulted from Hageman factor activation and was not due to inhibitor adsorption. 4. Asbestos treatment of plasma may be used as a presumptive test for Hageman trait.

Purification and isolation of certain intermediates formed prior to the activation of prothrombin.

ArticlePurification and Isolation of Certain Intermediates Formed Prior to the Activation of ProthrombinJoseph E. Flynn, and Robert W. CoonJoseph E. FlynnFrom the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York City, and Robert W. CoonFrom the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York CityPublished Online:31 Oct 1953https://doi.org/10.1152/ajplegacy.1953.175.2.289MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByCoagulation of the Blood22 November 2006Membrane-dependent reactions in blood coagulation: role of the vitamin K-dependent enzyme complexesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Vol. 1227, No. 3Activation of bovine factor VII (proconvertin) by factor XIIa (activated Hageman factor)1 May 2002 | Biochemistry, Vol. 16, No. 19Mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa(activated plasma thromboplastin antecedent)1 May 2002 | Biochemistry, Vol. 13, No. 22Simultaneous Purification of Bovine Prothrombin and Factor XJournal of Biological Chemistry, Vol. 248, No. 22Bovine factor X 1 (Stuart factor). Mechanism of activation by a protein from Russell's viper venom1 May 2002 | Biochemistry, Vol. 11, No. 26Physiology and Biochemistry of Blood CoagulationREFERENCESActa Physiologica Scandinavica, Vol. 75Application of A Generalized Rate Equation to the Gaseous Reduction of Iron Oxide18 July 2013 | Canadian Metallurgical Quarterly, Vol. 5, No. 4The Kinetics of Hematite Reduction by Partially Reformed Natural Gas18 July 2013 | Canadian Metallurgical Quarterly, Vol. 5, No. 3The Proteins of Blood CoagulationPurification and Properties of Bovine Factor X: Molecular Changes During Activation *1 May 2002 | Biochemistry, Vol. 3, No. 12Congenital deficiency of factor VII (hypoconvertinemia)The American Journal of Medicine, Vol. 37, No. 1The Activity of Lung Microsomes in Blood CoagulationJournal of Biological Chemistry, Vol. 239, No. 3Coagulation, Hemorrhage and ThrombosisNew England Journal of Medicine, Vol. 252, No. 12[16] Enzymes in blood clotting More from this issue > Volume 175Issue 2October 1953Pages 289-295 Copyright & PermissionsCopyright © 1953 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1953.175.2.289PubMed13114399History Received 29 June 1953 Published online 31 October 1953 Published in print 31 October 1953 Metrics