BackgroundUtilizing information and communication technologies through eHealth in exercise programs could support their delivery and improve clinical outcomes in children and adolescents with chronic suppurative lung diseases (CSLDs). This study aimed to systematically investigate the effects of eHealth exercise programs on clinical outcomes for this population.MethodsFive databases were searched from inception to April 12, 2024. Two researchers independently screened the retrieved results and rated the methodological quality of the included studies using the revised Cochrane Risk of Bias tool for randomized trials and the Risk of Bias in Non-Randomized Studies – of Interventions tool. The quality of evidence was graded using the GRADE approach. A narrative synthesis of findings was performed, and a meta-analysis was conducted to evaluate the effects of eHealth exercise programs on clinical outcomes that had data from ≥2 studies.ResultsSeven studies used eHealth exercise programs through active video games (n=3), videoconferencing (n=3), and a digital spirometer (n=1) lasting from 3 to 12 weeks. Five studies had participants with cystic fibrosis (CF). Results showed a greater improvement in the 6-minute walk test following the intervention compared to the control group; pooled estimate mean difference [37.2 meters (95%CI: 7.91 to 66.48), p=0.013]. Pulmonary function, exercise capacity, balance, peripheral and respiratory muscle strength, and HRQoL were also improved. Still, most studies involved a considerable risk of bias.ConclusionseHealth exercise programs can improve clinical outcomes in children and adolescents with CF. Further research is needed for other pediatric populations with CSLDs and also for comparisons with conventional exercise programs.
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