articleOverflow of catecholamine neurotransmitters to the circulation: source, fate, and functionsM. Esler, G. Jennings, G. Lambert, I. Meredith, M. Horne, and G. EisenhoferM. EslerBaker Medical Research Institute, Alfred Hospital, Melbourne,Australia., G. JenningsBaker Medical Research Institute, Alfred Hospital, Melbourne,Australia., G. LambertBaker Medical Research Institute, Alfred Hospital, Melbourne,Australia., I. MeredithBaker Medical Research Institute, Alfred Hospital, Melbourne,Australia., M. HorneBaker Medical Research Institute, Alfred Hospital, Melbourne,Australia., and G. EisenhoferBaker Medical Research Institute, Alfred Hospital, Melbourne,Australia.Published Online:01 Oct 1990https://doi.org/10.1152/physrev.1990.70.4.963MoreSectionsPDF (6 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByQuestioning the renoprotective role of L-type calcium channel blockers in chronic kidney disease using physiological modelingKyle H. Moore and John S. Clemmer1 October 2021 | American Journal of Physiology-Renal Physiology, Vol. 321, No. 4Preeminent role of the cardiorenal axis in the antihypertensive response to an arteriovenous fistula: an in silico analysisJohn S. Clemmer, W. Andrew Pruett, Robert L. Hester, and Thomas E. 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Dean1 October 1998 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 275, No. 4Dynamics of heart rate response to sympathetic nerve stimulationAbdelkader Mokrane and Réginald Nadeau1 September 1998 | American Journal of Physiology-Heart and Circulatory Physiology, Vol. 275, No. 3Influence of voluntary exercise on hypothalamic norepinephrineGavin W. Lambert, and Ingibjorg H. Jonsdottir1 September 1998 | Journal of Applied Physiology, Vol. 85, No. 3Different relationships of spillover to release of norepinephrine in human heart, kidneys, and forearmIrwin J. Kopin, Bengt Rundqvist, Peter Friberg, Jacques Lenders, David S. Goldstein, and Graeme Eisenhofer1 July 1998 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 275, No. 1Autonomic control of vasovagal syncopeDavid L. Jardine, Hamid Ikram, Christopher M. Frampton, Rachell Frethey, Sinclair I. Bennett, and Ian G. Crozier1 June 1998 | American Journal of Physiology-Heart and Circulatory Physiology, Vol. 274, No. 6Hypertensive disorders of pregnancyJournal of Hypertension, Vol. 16, No. 5Effect of β-adrenoceptor blockade on postexercise oxygen consumption and triglyceride/fatty acid cyclingMetabolism, Vol. 47, No. 4Effect of standing on neurohumoral responses and plasma volume in healthy subjectsGiris Jacob, Andrew C. Ertl, John R. Shannon, Raffaello Furlan, Rose Marie Robertson, and David Robertson1 March 1998 | Journal of Applied Physiology, Vol. 84, No. 3Insulin stimulates epinephrine release under euglycemic conditions in humansMetabolism, Vol. 47, No. 3Cardiovascular and humoral responses to sustained muscle metaboreflex activation in humansTakeshi Nishiyasu, Nobusuke Tan, Keiko Morimoto, Ryoko Sone, and Naotoshi Murakami1 January 1998 | Journal of Applied Physiology, Vol. 84, No. 1Estrogen Supplementation Decreases Norepinephrine-Induced Vasoconstriction and Total Body Norepinephrine Spillover in Perimenopausal WomenHypertension, Vol. 30, No. 6Cardiorenal epinephrine kinetics: evidence for neuronal release in the human heartMats Johansson, Bengt Rundqvist, Graeme Eisenhofer, and Peter Friberg1 November 1997 | American Journal of Physiology-Heart and Circulatory Physiology, Vol. 273, No. 5Sympathoinhibitory Response to Clonidine Is Blunted in Patients With Heart FailureHypertension, Vol. 30, No. 3Left Ventricular Norepinephrine and Epinephrine Kinetics at Birth in LambsCirculation Research, Vol. 81, No. 3Plasma Epinephrine and Norepinephrine Concentrations of Healthy Humans Associated With Nighttime Sleep and Morning ArousalHypertension, Vol. 30, No. 1Age-related increase in muscle sympathetic nerve activity is associated with abdominal adiposityP. P. Jones, K. P. Davy, S. Alexander, and D. R. Seals1 June 1997 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 272, No. 6Adrenomedullary Secretion of Epinephrine Is Increased in Mild Essential HypertensionHypertension, Vol. 29, No. 6Early Hemodynamic Effects of Left Atrial Administration of Epinephrine After Cardiac TransplantationAnesthesia & Analgesia, Vol. 84, No. 5Intravenous vs. oral rehydration: effects on subsequent exercise-heat stressJohn W. Castellani, Carl M. Maresh, Lawrence E. Armstrong, Robert W. Kenefick, Deborah Riebe, Marcos Echegaray, Douglas Casa, and V. Daniel Castracane1 March 1997 | Journal of Applied Physiology, Vol. 82, No. 3Effects of central metformin administration on responses to air-jet stress and on arterial baroreflex function in spontaneously hypertensive ratsJournal of Hypertension, Vol. 15, No. 3The Cardiac β-Adrenoceptor–Mediated Signaling Pathway and Its Alterations in Hypertensive Heart DiseaseHypertension, Vol. 29, No. 3Oxygen consumption in the heart, hepatomesenteric bed, and brain in young and elderly human subjects, and accompanying sympathetic nervous activityMetabolism, Vol. 45, No. 12The clinical utility of plasma catecholaminesJournal of Laboratory and Clinical Medicine, Vol. 128, No. 5Forearm training attenuates sympathetic responses to prolonged rhythmic forearm exerciseLawrence Sinoway, Jeffrey Shenberger, Gretchen Leaman, Robert Zelis, Kristen Gray, Robert Baily, and Urs Leuenberger1 October 1996 | Journal of Applied Physiology, Vol. 81, No. 4Hemodynamic and norepinephrine responses to pacing-induced heart failure in conscious sinoaortic-denervated dogsMarian Brändle, Kaushik P. Patel, Wei Wang, and Irving H. Zucker1 October 1996 | Journal of Applied Physiology, Vol. 81, No. 4Low-frequency Component of Heart Rate VariabilityAnesthesiology, Vol. 83, No. 4Insulin Modulation of Vascular Reactivity Is Already Impaired in Prehypertensive Spontaneously Hypertensive RatsHypertension, Vol. 26, No. 2Divergent Effects of Dihydropyridine and Phenylalkylamine Calcium Channel Antagonist Classes on Autonomic Function in Human HypertensionHypertension, Vol. 26, No. 1Compartmental analysis of norepinephrine kinetics in congestive heart failureThe American Journal of Cardiology, Vol. 75, No. 4Splanchnic and Renal Sympathetic Activity in Relation to Hemodynamics During Isoflurane Administration in PigsAnesthesia & Analgesia, Vol. 80, No. 1Insulin blunts sympathetic vasoconstriction through the alpha 2-adrenergic pathway in humans.Hypertension, Vol. 24, No. 4Corticotropin-release inhibitory factorTrends in Endocrinology & Metabolism, Vol. 5, No. 7Insulin blunts the natriuretic action of atrial natriuretic peptide in hypertension.Hypertension, Vol. 23, No. 6_pt_2Effect of β-adrenoceptor blockade on post-exercise oxygen consumptionMetabolism, Vol. 43, No. 5Enhanced cardiac norepinephrine release in patients with idiopathic ventricular tachycardia related to the occurrence of arrhythmiasAmerican Heart Journal, Vol. 127, No. 3Relation between tonic sympathetic and vagal control of human sinus node functionJournal of the Autonomic Nervous System, Vol. 46, No. 3Cyclosporine therapy after cardiac transplantation causes hypertension and renal vasoconstriction without sympathetic activation.Circulation, Vol. 88, No. 3Functional and neurochemical evidence for partial cardiac sympathetic reinnervation after cardiac transplantation in humans.Circulation, Vol. 88, No. 3Cardiac sympathetic nervous activity in congestive heart failure. Evidence for increased neuronal norepinephrine release and preserved neuronal uptake.Circulation, Vol. 88, No. 1Norepinephrine turnover and energy expenditure in Pima Indian and white menMetabolism, Vol. 42, No. 6Silent ischemia in unstable angina is related to an altered cardiac norepinephrine handling.Circulation, Vol. 87, No. 6Impaired glucose tolerance after endurance exercise is associated with reduced insulin secretion rather than altered insulin sensitivityMetabolism, Vol. 42, No. 3Regional homovanillic acid production in humansLife Sciences, Vol. 53, No. 1Catecholamines during cardiopulmonary resuscitation for cardiac arrestResuscitation, Vol. 24, No. 3Plasma norepinephrine responses to head-up tilt are misleading in autonomic failure.Hypertension, Vol. 19, No. 6_pt_2Changes in urinary catecholamine excretion after smoking cessationPharmacology Biochemistry and Behavior, Vol. 40, No. 4 More from this issue > Volume 70Issue 4October 1990Pages 963-985 Copyright & PermissionsCopyright © 1990 the American Physiological Societyhttps://doi.org/10.1152/physrev.1990.70.4.963PubMed1977182History Published online 1 October 1990 Published in print 1 October 1990 Metrics