Climate change is a serious challenge to human existence. It threatens efforts towards the attainment of sustainable development goals and aggravates conditions that lead to health inequities and inequalities for vulnerable populations. The study aimed to investigate knowledge and adaptation to climate change among people in Ghana. A nationally representative survey of Ghanaian adults (N = 674) was conducted from August 1, 2019, to December 31, 2019. Results showed that 43.9% of the respondents understood the meaning of climate change. Respondents perceived the causes of climate change to include burning of fossil fuel, deforestation, natural events such as ocean currents, carbon emission from vehicles and industries, agricultural emissions of nitrous oxide from fertilizers, and an act of God. About 53.1% and 41% of the male and female respondents, respectively, had an encounter with climate change-induced natural disasters. About two out of five respondents (43%) were either afraid or confused about climate change. Distilled or maintained public drainage from waste (30.2%) and clearing drains (25.6%) was the leading adaptation strategies towards climate change-induced natural disasters. Training (30.1%), national radio (27.7%), and television (19.1%) were the preferred leading methods for receipt of global warming information. These findings provide useful insights for policy directions. The government of Ghana and other stakeholders should develop a communication strategy to increase and sustain publicity and education on climate change to the citizenry.
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