Case Reports1 September 1947HEMOLYTIC ANEMIA COMPLICATING PRIMARY ATYPICAL PNEUMONIA WITH COLD ISOHEMAGGLUTININSBIAGIO BATTAGLIABIAGIO BATTAGLIASearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-27-3-469 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHemolytic anemia of varying severity, associated with cold isohemagglutinins, in primary atypical pneumonia has been previously reported.1, 2, 3 In a series of 200 cases, hemolytic anemia was noted in 11.2 It occurred at a time when the maximal titer of cold agglutinins is most often encountered, between the middle of the second and the middle of the fourth week. The presence of cold agglutinins in high titer does not necessarily result in such hemolytic phenomena.3 In some of the previously reported cases the administration of a sulfonamide compound has been considered a contributory cause of the hemolytic crisis.1The...Bibliography1. DAMESHEK W: Cold hemagglutinins in acute hemolytic reactions, Jr. Am. Med. Assoc., 1943, cxxiii, 77-80. CrossrefGoogle Scholar2. FINLAND M: Cold isohemagglutinins in primary atypical pneumonia, Jr. Clin. Invest., 1945, xxiv, 458-473. CrossrefGoogle Scholar3. YOUNG LE: Clinical significance of cold hemagglutinins, Am. Jr. Med. Sci., 1946, ccxi, 23-39. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, N. Y.*A hydrolysate of lactalbumin, supplied us by Frederick Stearns & Co.†Received for publication March 6, 1947. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Lab: Serological Diagnosis of Acquired Hemolytic AnemiaSerologie und Klinik der autoimmunhämolytischen ErkrankungenTYPE-SPECIFIC COLD AUTO-ANTIBODIES AS A CAUSE OF ACQUIRED HEMOLYTIC ANEMIA AND HEMOLYTIC TRANSFUSION REACTIONS: BIOLOGIC TEST WITH BOVINE RED CELLS*A. S. WIENER, F.A.C.P., L. J. UNGER, L. COHEN, J. FELDMANThe Syndrome of High-Titre Cold Hemagglutination. 1 September 1947Volume 27, Issue 3Page: 469-471KeywordsAgglutininsHemolytic anemiaPneumoniaSulfonamide ePublished: 1 December 2008 Issue Published: 1 September 1947 PDF downloadLoading ...