The uniaxial compression experiments with acoustic emission (AE) system are conducted to explore the coupling effect of the JRC and dip angle (α) on the mechanical and fracture characteristics of rock-like specimens containing weak-filled rough joints (WFRJ). With the increasing α, the variation of mechanical properties and the percentage of tensile cracks shows a trend of decreasing and then increasing; the variation of accumulated AE count shows a trend of increasing first, then decreasing, and then increasing again. The increasing JRC weakens the influence of α on mechanical properties but strengthens AE characteristics and the percentage of tensile cracks. The action mechanism of JRC for mechanical properties and AE characteristics is mainly reflected in the waviness and unevenness for α = 27˚ − 60˚ but only in the waviness for α = 0˚ − 90˚. The fracture pattern of WFRJ specimens is strongly related to the waviness of the joint profile. The weak-filled layer is usually broken near the inflection point. Then, the fracture of WFL induces the tensile fracture for α = 0˚ − 45˚ but shear fracture for α = 90˚ in the hard matrix from the inflection point. For α = 67˚, the fracture pattern is almost unaffected by the variation of JRC. Finally, the action mechanism of unevenness and waviness of joint profile on mechanical properties, AE characteristics and fracture pattern is analyzed.