Achillea Fragrantissima Research Articles

Irregular oxygenated monoterpenes from Achillea fragrantissima

From the aerial parts of A. fragrantissima, a santoline aldehyde and two highly oxygenated santoline derivatives were isolated in addition to several known compounds. The structures were elucidated by high field 1H NMR spectroscopy.

Glaucolides from Achillea fragrantissima

Achillea fragrantissima afforded, in addition to several known glaucolides, five new compounds whose structures were elucidated by high field 1H NMR spectroscopy.

The sesquiterpene lactones from achillea fragrantissima, I. Achillolide A and B, two novel germacranolides

With the aid of one- and two-dimensional multipulse NMR techniques the structure of two novel sesquiterpene lactones from Achillea fragrantissima growing in Israel were elucidated and their conformational behaviour investigated. Although both compounds are closely related in their structures their CD spectra indicate that they belong to different enantiomeric series.

Mechanisms of action of transmitters and other substances on smooth muscle.

Mechanisms of action of transmitters and other substances on smooth muscle.

Chromatographic Investigation of the Essential Oil of Achillea fragrantissima

Achillea fragrantissima oil was obtained by steam distillation in a yield of 0.83 per cent (v/w)−d23230.9001,[α]D20+8.25°,nD231.4640. It was light yellow and had a fresh aromatic odor. The oil was free from azulene, proazulene, aldehydes, and acids; but it contained the following: terpene hydrocarbons—α-pinene, d-myrcene, and sabinene; esters of formic, acetic, and butyric acids (the alcoholic parts of the esters were l-linalool, α-terpineol, n-hexen(3)-ol(1), and a small amount of nerol); ketones—ethyl n-amylketone and a short-chain unsaturated, unidentified ketone; phenols—eugenol and carvacrol; alcohols—l-linalool, n-bexen(3)-ol(1), 3-non-anol, and the possible presence of methanol, ethanol, and n-butanol is indicated.