The key technologies for advanced autonomous vehicles include those relating to perception, decision making, and execution. Path-tracking control in autonomous vehicles is heavily dependent on their positioning system. Therefore, the development of low-cost and reliable positioning systems is crucial to improving perception and decision-making technologies for autonomous vehicles. Although the accuracy of the global positioning system (GPS) is extremely high, it is vulnerable to interference. Further, despite the low positioning accuracy of inertial navigation systems (INSs), their robustness is notably high. Therefore, an integrated navigation information method based on the Adaptive Particle Filter and the Iterative Kalman Filter (APF-IKF) was developed in this study. Firstly, an integrated navigation system model was established. Then, the IKF was adopted to estimate the speed, latitude and longitude errors of the INS. Thirdly, the newest estimated error results were introduced into the APF to optimize the distribution function, and the particle quality was improved. In this process, the APF can filter non-Gaussian noise, preliminarily estimate the error, optimize the result with the IKF and correct the output information of the INS with the final estimated error. Finally, by using differential GPS positioning as the benchmark, we built a real-vehicle test platform with a low-cost and low-precision GPS and inertial units and carried out a series of real-vehicle tests. The experimental results show that compared with the traditional KF method, APF-IKF can significantly improve the positioning accuracy and robustness of the system.