Accumulation Of Harmful Substances Research Articles

Contribution of Direct Cerebral Vascular Transport in Brain Substance Clearance.

The accumulation of harmful substances has long been recognized as a likely cause of many neurodegenerative diseases. The two classic brain clearance pathways are cerebrospinal fluid (CSF) and vascular circulation systems. Since the discovery of the glymphatic system, research on the CSF pathway has gained momentum, and impaired CSF clearance has been implicated in virtually all neurodegenerative animal models. However, the contribution of the direct participation of vascular transport across the blood-brain barrier in clearing substances is often ignored in glymphatic papers. Supportive evidence for the direct involvement of parenchymal vasculature in substance clearance is accumulated. First, multiple mechanisms have been proposed for the vascular drainage of exogenous and endogenous substances across the blood-brain barriers. Second, the "traditional" role of arachnoid villi and granulations as the main site for CSF draining into the vasculature system has been questioned. Third, MRI studies using different CSF tracers indicate that parenchymal vasculature directly participates in tracer efflux, consistent with immunohistochemical findings. Here we will review evidence in the literature that supports the direct participation of the parenchymal vascular system in substance clearance, in addition to the CSF clearance pathways.

Role of Lifestyle Changes and Natural Herbs in the Management of Hepatic Health

Liver ailments are significant contributors to human illness and death globally. The prevalence of liver disorders is increasing owing to the widespread prevalence of hepatitis and alcohol addiction. These conditions can be triggered by infection, trauma, exposure to pharmaceuticals or hazardous substances, autoimmune disorders, or genetic abnormalities resulting in the accumulation of harmful substances. Despite advances in understanding the causes underlying hepatic dysfunction, no standard pharmaceutical therapy is available. The only currently advised option is to make lifestyle changes such as diet, intermittent fasting, and increased physical exercise. However, a lack of compliance continues to impede this strategy. As a result, there is an apparent need to characterize novel therapeutic alternatives. Current advances in the communication between the gut and hepatic tissue open new avenues for better explaining the molecular mechanisms behind the pathology of hepatic illness. Natural bioactive compound research has emerged as an appealing strategy for overcoming lifestyle change resistance. The current study aims to review some of the identified compounds and other herbal approaches with favourable characteristics to hepatic health. This review study discusses their protective properties, mode of action in ameliorating the major pathological events involved in liver disorders, and therapeutic applications.

Co-treatment with free nitrous acid and calcium peroxide regulates microbiome and metabolic functions of acidogenesis and methanogenesis in sludge anaerobic digestion

Wasted activated sludge (WAS) is a promising feedstock for carbon management because of its abundance and carbon-neutral features. Currently, the goal is to maximize the energy in WAS and avoid secondary toxic effects or accumulation of harmful substances in the environment. Chemical pretreatment is an effective strategy for enhancing WAS disintegration and production of short chain fatty acids (SCFAs). However, the role of pretreatment in shaping the core microbiome and functional metabolism of anaerobic microorganisms remains obscure. Here, the mechanisms of SCFA synthesis and microbiome response to free nitrous acid (FNA) and calcium peroxide (CaO2) co-treatment during sludge anaerobic digestion (AD) were investigated. The combination of FNA and CaO2 enriched acidogenic Macellibacteroides, Petrimonas, and Sedimentibacter to a relative abundance of 15.0%, 10.3%, and 7.3%, respectively, resulting in an apparent increase in SCFA production. Metagenome analysis indicated that FNA + CaO2 co-treatment facilitated glycolysis, phosphate acetyltransferase-acetate kinase pathway, amino acid metabolism, and acetate transport, but inhibited CO2 reduction and common pathway of methanogenesis compared with the untreated control. This work provides theoretical insights into the functional activity and interaction of microorganisms with ecological factors.

Identifying relationships between disposal behavior, purchase pattern, price, and awareness with the e-waste management systems

E-waste contains toxic materials which require a special treatment for avoiding environmental pollution and accumulation of harmful substances in human body. According to BTRC there are 173.357 million mobile phone subscribers up to February 2021 in Bangladesh. Among all ICT appliances mobile phone has shortest average lifespan of 2 years. Due to increasing availability of e-services in public and private sector, the use of computer and laptop and internet is growing hurriedly during covid-19. Although Bangladesh has policies and instructions to develop ICT, there are no proper instructions and guidelines for management of the waste of technology. If government doesn’t take proper initiatives to control e-waste the toxic substances of these technological appliances spread over everywhere and pollute the environment, the development project of Digital Bangladesh turns into in development hazard. The aim of this paper was to identify the factors influencing towards the e-waste management system in Bangladesh. Through analyzing 250 questionnaires by SmartPLS software, we documented a positive relationship (p 0.05) between price and e-waste management system in Bangladesh.

Evaluation of Rational Antibiotic Use in Non-Pneumonia ARI Disease Patients in the Working Area of Health Center "X" in Mining Area PT. ANTAM, Tbk Pomalaa Subdistrict


 
 
 
 
 
 
 
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 Introduction: Infection of the airways is a common disease in the community. Most respiratory infections are caused by infections, but can also be caused by installation of organic materials or chemical vapors and inhalation of dust materials containing allergens. The main effects of dust on workers are both acute lung disorders and chronic physiological dysfunction, eye irritation, sensory irritation, and accumulation of harmful substances in the body. This study is intended to find out the rigors of antibiotics in cases of non-pneumonia airway infection disease in the working area of health center "X" in the mining area of PT. Antam Tbk Pomalaa Subdistrict June-December 2021 period.
 Method: Data retrieval is done descriptively by taking secondary data in the health center "X" mining area pt. Antam Tbk Pomalaa Subdistrict. The maximum value of antibiotics in ARI non-pneumonia disease is the maximum limit set by the health department, which is 20%.
 Result: The study there were 230 patients affected by non-pneumonia ARI disease in health center "X" mining area PT. Antam Tbk Pomalaa Subdistrict.
 Conclusion: The use of antibiotics in ARI non-pneumonia in health center "X" Pomalaa subdistrict is rational.

Contributions of Beneficial Microorganisms in Soil Remediation and Quality Improvement of Medicinal Plants.

Medicinal plants (MPs) are important resources widely used in the treatment and prevention of diseases and have attracted much attention owing to their significant antiviral, anti-inflammatory, antioxidant and other activities. However, soil degradation, caused by continuous cropping, excessive chemical fertilizers and pesticide residues and heavy metal contamination, seriously restricts the growth and quality formation of MPs. Microorganisms, as the major biota in soil, play a critical role in the restoration of the land ecosystem. Rhizosphere microecology directly or indirectly affects the growth and development, metabolic regulation and active ingredient accumulation of MPs. Microbial resources, with the advantages of economic efficiency, harmless to environment and non-toxic to organisms, have been recommended as a promising alternative to conventional fertilizers and pesticides. The introduction of beneficial microbes promotes the adaptability of MPs to adversity stress by enhancing soil fertility, inhibiting pathogens and inducing systemic resistance. On the other hand, it can improve the medicinal quality by removing soil pollutants, reducing the absorption and accumulation of harmful substances and regulating the synthesis of secondary metabolites. The ecological and economic benefits of the soil microbiome in agricultural practices are increasingly recognized, but the current understanding of the interaction between soil conditions, root exudates and microbial communities and the mechanism of rhizosphere microecology affecting the secondary metabolism of MPs is still quite limited. More research is needed to investigate the effects of the microbiome on the growth and quality of different medicinal species. Therefore, the present review summarizes the main soil issues in medicinal plant cultivation, the functions of microbes in soil remediation and plant growth promotion and the potential mechanism to further guide the use of microbial resources to promote the ecological cultivation and sustainable development of MPs.

Effect of Nickel Mining on Acute Respiratory Infection Cases in Boenaga Village, Lasolo District, North Konawe Regency

Introduction: Nickel mining industry with air with nickel dust and combu stion gases. The main effects of dust on workers are either acute lung disorders or chronic physiological disorders, eye irritation, sensory irritation, and accumulation of harmful substances in the body. One of the negative impacts of nickel processing activities is environmental degradation which is characterized by air and many diseases related to the respiratory tract. This greatly affects the people who live close to mining areas, based on data from the Lasolo Island Health Center shows that ARI cases in 2020 were 126 cases, Asthma 85 cases, and Toddler Pneumonia 23 cases. The purpose of this study was to determine the effect of mining on cases of ARI in mining areas in the village of Boenaga.
 Method: The type of research used in this study is an observational study with a cross sectional analytic study.
 Result: The results showed that there was a relationship between dust exposure and cases of respiratory disease.
 Conclusion: The condition of indoor and outdoor air quality in exposed areas was higher than in non-exposed areas, but all of these are still below the permissible threshold value. The incidence of ARI in exposed locations increased significantly compared to non-exposed locations in Pomalaa district.

Assessment of the Impact of Motor Transport on the Ecological State of Atmospheric Air of Urbanized Areas

The article reflects the results of studies on assessing the impact of pollutants entering the atmospheric air from vehicles on the ecological state of the urban environment, analyzes the distribution of emissions of the main pollutants in the context of data for the North Caucasian Federal District and considers the dynamics of the qualitative composition of atmospheric air using the example of the city of Stavropol. As a result of analyzing the data for 2014-2019 in the district, a decrease in the intake of carbon monoxide, nitrogen oxide, sulfur oxide, volatile organic compounds into the atmospheric air from vehicles was found, an increase in carbon content was noted. The study of pollutants included in the daily monitoring program and the intensity of vehicles showed the maximum presence of oxides of sulfur, nitrogen, carbon at 14:00, an increase in gas content at 20:00 indicating the accumulation of harmful substances in the atmosphere during the day and negative impact on the ecological situation of the city.

Prerequisites for taking into account the influence of air exchange in the design of residential districts in the regulatory documentation

Many cities face environmental problems, which are currently receiving a lot of attention. The layout of the city' micro-district corresponding to the regulations can provide the most favorable environmental conditions due to air exchange. The building of the city has been developing for centuries, microdistricts have a layout that was regulated by the law, valid at the times of their construction. The object of research is the processes of air exchange in city districts – on the example of Krasnoyarsk. The method of analysis of scientific sources and standards was used for the study, which allowed determining the chronology of changes in factors affecting air exchange and building blocks. The study includes the solution of the following tasks: analysis of the building regulations affecting air exchange in the neighborhood; to determine the principles of planning a residential neighborhood and establish their compliance with the standards on the example of the city of Krasnoyarsk; to consider the prerequisites for the implementation of an environmental aspect in building codes. For the sake of clarity of the data obtained on the problems of air exchange and the principles of development of microdistricts, the history of the planning structure of the development of Krasnoyarsk is investigated. As a result of the study, a general characteristic of the development of regulatory requirements for the development of microdistricts has been identified and presented. The relevance of the topic is determined by the presence of a problem with the accumulation of harmful substances in residential neighborhoods in Krasnoyarsk. In the current planning methods of development in some residential areas of Krasnoyarsk, this problem cannot be solved due to the increase in height and density of buildings while maintaining the same values of distances between buildings, since the regulatory requirements of insolation do not ensure effective ventilation of the district. According to the results of the study, it was concluded that not all previous standards included effective regulations to ensure the necessary air exchange, or they are completely absent. In these standards, factors affecting effective air exchange (height of buildings, distances between buildings and the angle of the buildings) were determined by other requirements, such as sanitary and fire safety standards, insolation requirements.

Distribution, Formation and Human Health Risk of Fluorine in Groundwater in Songnen Plain, NE China

Songnen Plain is one of the three great plains in northeast China with abundant groundwater resources. The continuous population growth and the rapid development of agriculture and economy in China has caused a series of environmental problems in the plain, such as endemic diseases caused by the accumulation of harmful substances in drinking water. This paper conducts a systematic investigation of fluorine in the groundwater of Songnen Plain. The results showed that fluorine was widespread in the groundwater of the plain in the concentration range of BDL–8.54 mg·L−1, at a mean value of 0.63 mg·L−1 and detectable at a rate of 85.91%. The highest concentrations of fluorine were found in central and southwest areas of the plain. The concentration exceeded the guideline values for fluorine in drinking water and may have varying degrees of adverse effects on adults, and especially children, in the study area. The fluorine in groundwater mainly came from the dissolution of fluorite and other fluorine-containing minerals, and the concentrations and distribution of fluorine were affected by cation exchange, groundwater flow field and hydrochemical indexes (pH, TDS and HCO3−). The study provides scientific basis for the investigation, evaluation and prevention of endemic diseases caused by fluorine.

STUDY OF THE SORPTION ABILITY OF NATURAL SORBENTS ISOLATED FROM THE CAMPSIS RADICANS

Currently, more and more chemical additives are used in food products, which leads to the accumulation of harmful substances in the body. Therefore, it is relevant to search for new substances of natural origin with detoxification properties. The aim of the work was to determine the sorption ability of pectin substances and water-soluble polysaccharides isolated from the leaves and flowers of the campsis radicans. By the method of N.K. Kochetkova and M. Sinner isolated polysaccharides from water-borne campsis leaves and flowers: water-soluble polysaccharides, pectin, hemicellulose A and hemicellulose B. The adsorption capacity of pectins and water-soluble polysaccharides was studied on the basis of their complexing properties with respect to lead ions. The determination of their content in the raffinate was carried out by titration with a solution of sodium ethylenediaminetetraacetate disubstituted. To evaluate the nature of the sorbent, the calculated Langmuir and Freindlich equations were used. A study of the sorption ability of polysaccharides isolated from leaves of the campsis radicans showed the presence of a high binding ability of Pb2+ ions in pectin substances was associated with 54.2%, and in water-soluble polysaccharides – 37.5%. Polysaccharides isolated from the flowers of the campsis radicans showed sorption activity in the ratio: pectin substances – 32.6%, water-soluble polysaccharides – 80.1%.
 The expressed complexing ability of the studied polysaccharides with respect to lead ions was revealed. The ratio of the experimental and calculated data on the values of the adsorption of lead ions showed that the sorption process is largely subordinate to the Langmuir equation. Pectic substances and water-soluble polysaccharides obtained from the leaves and flowers of the campsis radicans can be considered as effective detoxifiers. Further study of the physicochemical properties will make it possible to assess the possibility of their biomedical use.

New estimates of eco-intensity considering the hazardous industrial pollution accumulation

The paper proposes a new approach to environmental and economic assessments based on the author’s economic and mathematical model that takes into account the accumulation of hazardous pollutants in natural environments. It also presents the results of calculations showing the dynamics of the increase in the negative impact depending on the natural assimilation of pollutants. This data can be considered as a quantitative assessment of the “environmental cost” that society pays by consuming goods the production of which is accompanied by the accumulation of long-lived pollutants. It is shown that this “price” can very significantly exceed the eco-intensity calculated without taking into account the accumulation of pollutants. Thus, the accumulation of pollutants as a result of economic activity is an important factor in the context of the impact on the ecological and economic balance. The implementation of the results obtained in the adjustment of the calculations of payments for negative environmental impact is proposed: to set payments per unit of production which are not proportional to emissions, but proportional to the eco-intensity calculated according to the proposed methodology. In this case, the accumulation of harmful substances in natural environments, the added value of production and the timing of project implementation will be taken into account. This corresponds to the concept of “green” economy, which provides the growth of well-being and quality of life with the maximum possible reduction of the negative anthropogenic pressure and improvement of the quality of the environment.

Evaluation of the effectiveness of the fungicidal effect of drugs against pathogens of cultivated grapes (Vitis vinifera L.)

The Vitis vinifera L. cultural grape includes many varieties that are highly valued in winemaking and viticulture, as raw materials for the production of fresh and dried berries, for the production of wines. The fruits of cultural grapes play an important role in medicine, where they are used as a source of substances with high antioxidant activity. Grapes are often affected by phytopathogenic fungal infections. In recent years, a large number of reports have appeared in the literature about the acquisition of resistance of microorganisms to industrial pesticide preparations, which in turn leads to an increase in drug doses, the multiplicity of treatments and the accumulation of harmful substances in the environment and in the plants themselves. In this study, we evaluate the effectiveness of the fungicidal action of industrial preparations and plant extracts in relation to two native species of fungi (V1 and V2) isolated from the leaves of cultivated Vitis vinifera L. grapes, as well as against the phytopathogen Alternaria solani K-100054. Minimal inhibitory (MIC) and fungicidal concentrations (MFC) were detected for each sample. Ethanol extracts of plants showed low antimycotic activity in relation to fungi cultures isolated from grapes. Activity started from 0.0625%. The best result among industrial fungicides was shown by the drug “Maxim”, whose MIC values was 0.097 μg/mL, and the MFC varies between 3.125-12.5 μg/mL for pathogens V1 and V2, respectively.

Effects of biochar and biofertilizer on cadmium-contaminated cotton growth and the antioxidative defense system

Consistent use of large amounts of fertilizers, pesticides, and mulch can cause the accumulation of harmful substances in cotton plants. Among these harmful substances, cadmium (Cd), an undegradable element, stands out as being particularly highly toxic to plants. The objective of this study was to evaluate the ability of biochar (3%) and biofertilizer (1.5%) to decrease Cd uptake, increase cotton dry weight, and modulate the activities of photosynthetic and peroxidase (POD), superoxide dismutase (SOD), catalase enzyme (CAT) in cotton (Gossypium hirsutum L.) grown in Cd-contaminated soil (0, 1, 2, or 4 mg Cd kg−1 soil) in pots. These studies showed that, as expected, exogenous Cd adversely affects cotton chlorophyll and photosynthesis. However, biochar and biofertilizer increased cotton dry weight by an average of 16.82% and 32.62%, respectively. Meanwhile, biochar and biofertilizer decreased the accumulation of Cd in cotton organs, and there was a significant reduction in the amount of Cd in bolls (P < 0.05). Biochar and biofertilizer have a positive impact on cotton chlorophyll content, net photosynthesis, stomatal conductance, transpiration rate, and intercellular CO2 concentration. Thus, the addition of biochar and biofertilizer promote cotton growth. However, biochar and biofertilizer increased the SOD activity of leaves (47.70% and 77.21%), CAT activity of leaves (35.40% and 72.82%), SOD activity of roots (33.62% and 39.37%), and CAT activity of roots (36.91% and 60.29%), respectively, and the addition of biochar and biofertilizer decreased the content of MDA and electrolyte leakage rate. Redundancy analyses showed that biochar and biofertilizer also improved SOD and POD activities by reducing the heavy metal-induced oxidative stress in cotton and reducing Cd uptake in cotton organs. Therefore, biochar and biofertilizer have a positive effect on the growth of cotton.

Procedure and installation for processing iron-containing metallurgical waste

The review and the analyses of publications in the domain of recycling crushed iron containing metallurgical waste, including dust, slam, etc., has made it possible to determine the generated tendency of their processing. As this waste contains a significant amount of harmful admixtures, their recycling in the basic manufacture process results in accumulation of harmful substances that negatively affect the operation of metallurgical units. Therefore their processing in insulated installations is strongly recommended nowadays. The first installations had high capital and current expenditures. Creation of rotary-hearth kilns has allowed to lower essentially current expenditures, however capital expenditures remaining high. Besides the rise in prices for heating gas under the conditions of Ukraine made the installations unprofitable. That is why there arises a problem of cardinal reduction of such installations employment as well as current expenditures for their maintenance. The executed investigations have made it possible to develop both the procedure and the installation realizing this procedure. So, the principal differences of the given procedure from the known ones are simultaneous crushing of the charge to micron level, the use of bichofit МgCl2·6Н2О as the connector and the flux, preliminary consolidation of the charge material in the runners and application of a special multizonal induction furnace for metallic coating. The set of the measures realized on the given procedure, raises the degree of metallic coating of iron from 90%, realized according to the known procedure, up to 99,6% and reduces the restoration cycle by 4-8 times, i. e. from 1-2 h. to 0,25 h. It also allows to improve ecological environment and to reduce the total metal loss by 3-5%. The installation has been developed as a mobile variant for which the equipment is arranged as separate units fixed on welded frames. The installation has been developed with regard to the equipment fabricated in Ukraine, and does not depend on the deliveries of the component parts and the connectives from abroad; it considerably reducing its cost

Lakes in the era of global change: moving beyond single-lake thinking in maintaining biodiversity and ecosystem services.

The Anthropocene presents formidable threats to freshwater ecosystems. Lakes are especially vulnerable and important at the same time. They cover only a small area worldwide but harbour high levels of biodiversity and contribute disproportionately to ecosystem services. Lakes differ with respect to their general type (e.g. land-locked, drainage, floodplain and large lakes) and position in the landscape (e.g. highland versus lowland lakes), which contribute to the dynamics of these systems. Lakes should be generally viewed as 'meta-systems', whereby biodiversity is strongly affected by species dispersal, and ecosystem dynamics are contributed by the flow of matter and substances among locations in a broader waterscape context. Lake connectivity in the waterscape and position in the landscape determine the degree to which a lake is prone to invasion by non-native species and accumulation of harmful substances. Highly connected lakes low in the landscape accumulate nutrients and pollutants originating from ecosystems higher in the landscape. The monitoring and restoration of lake biodiversity and ecosystem services should consider the fact that a high degree of dynamism is present at local, regional and global scales. However, local and regional monitoring may be plagued by the unpredictability of ecological phenomena, hindering adaptive management of lakes. Although monitoring data are increasingly becoming available to study responses of lakes to global change, we still lack suitable integration of models for entire waterscapes. Research across disciplinary boundaries is needed to address the challenges that lakes face in the Anthropocene because they may play an increasingly important role in harbouring unique aquatic biota as well as providing ecosystem goods and services in the future.

Productivity and accumulation of heavy metals in grain of various genotypes of spring durum wheat under conditions of soil contamination with cadmium and zinc

The developed industry has an adverse effect on the ecological state of the environment, accompanied by the accumulation of harmful substances in the soil, including heavy metals. Therefore, thecreation of technogenically resistant varieties of agricultural crops is one of the components of environmentally friendly technologies. This study is aimed at studying various genotypes of spring durum wheatfor their resistance to the accumulation of cadmium and zinc in grain, which is a commercial part ofthe product. The content of the studied heavy metals in the soil of the root zone of various genotypesof spring durum wheat was investigated. The accumulation of the studied elements in seeds was determined, which is the most important studied indicator. The indices of productivity and survival of springdurum wheat genotypes were investigated in the field of natural pollution of the environment with heavymetals. The most stable and sensitive to the action of cadmium and zinc genotypes were revealed. Thestructure of spring wheat productivity from the collection and the relationship of its elements wereanalyzed. The identified resistant genotypes are recommended for further study of their productivityand survival in weather conditions of the East Kazakhstan region in field experiments to identify formspromising for agricultural production.Key words: cadmium, zinc, spring durum wheat.

Environmental issues of agriculture as a consequence of the intensification of the development of agricultural industry

The paper deals with the environmental issues of agriculture. Examples are given that pose a threat to the vital activity of living organisms from various types of agricultural and human activities. The subject of the study is the analysis of environmental issues arising from the intensification of the development of agricultural industry. Intensive agricultural activity leads to pollution of surface rivers, lakes, seas and groundwater, soil degradation and aquatic ecosystems; violation of the water regime in large areas during drainage and irrigation; desertification due to wind erosion; destruction of natural habitats of living organisms of flora and fauna. An urgent problem of agriculture is a decrease in the content of vitamins and microelements in crop production and the accumulation of harmful substances in them. The reasons for these negative processes are soil degradation, intensification of agricultural production.

Progress in the treatment of atrophic age-related macular degeneration

Atrophic age-related macular degeneration (AMD) does not show obvious loss of visual function in the early stage, so it is not easy to be taken seriously. In the advanced stage, most of the patients suffered from macular area retinal map atrophy, which affected night vision and central vision. Drugs currently used in clinical or clinical trials to treat atrophic AMD include drugs for improving choroidal perfusion, reducing the accumulation of harmful substances, preventing oxidative stress injury, inhibiting inflammatory reactions, as well as neuroprotectants and lipid metabolism drugs. Stem cell transplantation for atrophic AMD is currently the most promising treatment. In theory, it is feasible to replace atrophic AMD with retinal photoreceptor cells and RPE cells derived from human stem cell differentiation. However, there are still many problems to be solved, such as how to improve the efficiency of directional differentiation of seed cells and how to ensure the safe and effective RPE cell transplantation and survival after transplantation. At present, several studies have found that multiple locus mutations are associated with atrophic AMD, so gene therapy also plays an important role in the development of the disease. Key words: Macular degeneration/therapy; Geographic atrophy; Review

Studying the Effects of Essential Oil Bearing Plants on the Physico-Chemical Characteristics of Vodka

Ancient vodka was an alcoholic tincture made of herbs and berries, where ethyl alcohol was modified by the many complex combinations of healthy substances. The ancient vodka makers preserved the preparation principle based on using an alcohol purified of harmful impurities in combination with herbal components; subsequent processing was what distinguished alcoholic drinks from medications. Thus, Russia finally invented and popularized aromatic vodkas, tinctures, liqueurs, and rataphias, which then became popular worldwide. Essential oil bearing plants have been known to human since long ago; they boast a high content of biologically active agents and minerals. They are broadly used in perfumery, cosmetics, confectionary, paint and liqueur production. When used in making alcohol, the beverage is infused with the biologically active components of such plants. Modern use of plants for vodka aromatization is mainly due to strong competition in the market, the producers’ marketing policy, or the need to achieve a desired taste or aroma. There are very few publications that describe the effects of biologically active agents on the human body, whereby drinking vodka has a hepatoprotective effect. In our quest for new vodka formulations, we added the total aromatic alcohol produced from essential oil bearing plants and found out that such vodka was less toxic while having unquestionable organoleptic advantages. It was found out that the use of aromatic alcohols based on aromatic plants did not cause any accumulation of harmful substances in special vodkas. We have developed new formulations for vodkas we named Zemlyanichnaya (Strawberry), Brusnichnaya (Cowberry), and Chernichnaya (Blueberry) based on total aromatic alcohols produced from aromatic plants growing in RNO-Alania; we found out that the use of aromatic alcohols based on aromatic plants did not cause any accumulation of harmful substances in special vodkas.