Academy Of Dermatology Research Articles

24th European Academy of Dermatology and Venereology.

The 24th European Academy of Dermatology and Venereology was held in Copenhagen, Denmark, from 7-11 October 2015. It has become Europe's biggest meeting of its kind with roughly 10,000 participants, approximately 3000 abstracts and about 180 exhibitors from all over the world. The organizers offer a venue for the latest cutting edge research and newest developments. Thus, their goal is to foster progress in clinical care and promote scientific excellence related to dermatovenereology for the benefit of patients with skin diseases.

American Academy of Dermatology (AAD) - 74th Annual Meeting. Washington, D.C., USA - March 4-8, 2016

American Academy of Dermatology (AAD) - 74th Annual Meeting. Washington, D.C., USA - March 4-8, 2016

Vulvar edema and weight loss in a pediatric patient

From the Department of Dermatology, Virginia Commonwealth University, Richmond, Virginia. Funding sources: None. Conflicts of interest: None declared. Correspondence to: Alex G. Ortega-Loayza, MD, Department of Dermatology, Virginia Commonwealth University, 401 N 11th St, Nelson Clinic, 5th fl, Ste 520, Richmond, VA 23219. E-mail: alex. ortegaloayza@vcuhealth.org. J Am Acad Dermatol 2015;73:e193-4. 0190-9622/$36.00 a 2015 by the American Academy of Dermatology, Inc. http://dx.doi.org/10.1016/j.jaad.2015.08.002

What "leaning in together" means to me.

TheWomen’s Dermatologic Society luncheon at this year’s American Academy of Dermatology meeting featured a speaker whose talk centered on the problems associated with gender stereotypes in negotiations.Although much of her talk was focused on the impact this has on women, one of her final comments resonated with me: “Rigid ideas about gender roles are really limiting, especially for men.”I was so glad to hear her say this.For the last year, I have been wondering how many working professionals like me deal with this problem on a regular basis.Her words inspired me to write this article.

Crusted dusky red papules in a newborn

From the University of Kentucky College of Medicine, Lexington, and the Section of Dermatology, Medical College of Georgia at Georgia Regents University, Augusta. Funding sources: None. Conflicts of interest: None declared. Presented at the Georgia Society of Dermatology and Dermatologic Surgery Meeting, June 7-9, 2013. Correspondence to: Jennifer L. Brooks, BS, Medical Student, MS4, University of Kentucky College of Medicine, 138 Leader Avenue, Lexington, KY 40506. E-mail: Jennifer.brooks@uky.edu. J Am Acad Dermatol 2015;73:e1-2. 0190-9622/$36.00 a 2015 by the American Academy of Dermatology, Inc. http://dx.doi.org/10.1016/j.jaad.2015.01.047

Research Unit of the Spanish Academy of Dermatology and Venerology Foundation

Research Unit of the Spanish Academy of Dermatology and Venerology Foundation

American Academy of Dermatology, 73rd Annual Meeting: Advisors' Introduction

American Academy of Dermatology, 73rd Annual Meeting: Advisors' Introduction

Evaluation of life quality in patients with acnes vulgaris

Abstract. Preliminary few studies indicate that age, gender and duration of acne vulgaris (acne) affect the quality of life of these patients.Objective - to assess the impact of the duration and severity of acne on quality of life of patients in gender, age and professional aspects in connection with the treatment.Material and methods: 98 patients with acne aged 18-29 years, among whom 36 were males (36,73 %), and 62 (63,26 %) females have been examined. The assessment of acne severity classification was carried out according to the classification of the American Academy of Dermatology, while the quality of their life was assessed by means of SF- 36 questionnaire.Results. Mild acne was found in 6 (6,12 %) patients, moderate one in 72 (73,47 %), severe one in 20 (20,41 %) cases. It was established that clinically significant severity of acne was more common in younger male patients (22 years). However, a greater impact on quality of life was found in female patients, older than 22 years, with professions associated with being among a large group of people and in case of long course (more than 4-5 years) of dermatosis. Mild acne had little impact on quality of life.Standard complex acne treatment during two months significantly improved quality of life indicators of patients with moderate degree of acne and most of the indicators in those with severe disease, which, however, didn’t reach the indicators in the people of the control group, and it shows the necessity to improve the programme of treating and preventive measures concerning such patients.Conclusion: Patients with acne have significant changes in life quality, depending on their gender, age and professional peculiarities as well as on the severity of dermatosis course. Determining the indicators of life quality by means of SF-36 questionnaire is an important aspect of the patient’s physical and psychiatric health assessment as well as a reliable criterion of their treatment efficacy.

GRAPPA Fellows Symposium Adjacent to the European Academy of Dermatology and Venereology (EADV) Congress, Istanbul, 2013: A Meeting Report

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) organized its second Fellows Symposium adjacent to the European Academy of Dermatology and Venereology (EADV) congress in Istanbul in October 2013. Wolf-Henning Boehncke from Geneva, Brian Kirby from Dublin, and Diamant Thaci from Lübeck formed the faculty. The 9 best-ranked abstracts submitted to this symposium were presented and discussed in detail. Five abstracts focused on comorbidities in patients with psoriasis or psoriatic arthritis; summaries of all abstracts are included herein.

Efinaconazole 10% nail solution: a new topical treatment with broad antifungal activity for onychomycosis monotherapy.

Topical therapies for onychomycosis are associated with less adverse events than systemic therapies, but poor nail penetration limits their efficacy. Consequently, an efinaconazole 10% nail solution was developed. To review the evidence supporting the usefulness of efinaconazole monotherapy in onychomycosis management. PubMed and clinicaltrials.gov databases and abstracts from the 2013 annual meeting of the American Academy of Dermatology were searched in April 2013 using the terms "efinaconazole," "IDP-108," and "KP-103." In vitro, efinaconazole possesses a broad antifungal activity similar or superior to that of other antifungals. Its low affinity for keratin results in good nail penetration. Efinaconazole 10% nail solution administered daily for 36 or 48 weeks to treat mild to moderate toenail onychomycosis caused by dermatophytes results in complete and mycologic cure rates of 15 to 25% and 53 to 87%, respectively. No serious skin reaction is associated with its use. Efinaconazole 10% nail solution is a promising new treatment for onychomycosis.

72nd Annual Meeting of the American Academy of Dermatology

In his presentation on the co-morbidities of pediatric AD, Associate Professor Eric Lawrence Simpson (Oregon Health and Science University, Portland, OR, USA) discussed the higher prevalence of food allergy compared with the general pediatric population. Unfortunately, possible preventative measures such as breastfeeding or delaying solid food have not been proven to be helpful. In fact, a recent study has shown that increased food diversity in the first year of life is inversely associated with allergic diseases [1], and current recommendations are that there should be no restriction on food introduction after 6 months of age. Interestingly, various studies including one by Simpson’s group [2] have shown an increased prevalence of attention deficit hyperactivity disorder (ADHD) in patients with AD. This association was confirmed by Deckert et al. [3] in their 2014 overview of systematic reviews. It is uncertain if all of these AD patients truly have ADHD or whether the effect of their AD on sleep is contributing to their symptoms. However, severe AD should be treated aggressively to decrease co-morbidities such as neuropsychological effects. 2 New Rosacea Therapies

GRAPPA Fellows Symposium Adjacent to the European Academy of Dermatology and Venerology Meeting, Verona, 2012: A Meeting Report

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) organized a Fellows Symposium adjacent to the European Academy of Dermatology and Venerology (EADV) spring meeting in Verona, Italy, in 2012. Wolf-Henning Boehncke from Geneva and Brian Kirby from Dublin formed the faculty. Five papers were presented, followed by extended discussions among participants and faculty. Two contributions were on comorbidities of psoriasis patients and 2 on treatment of non-plaque-type psoriasis; the fifth presentation was a discussion of possible modes of action of vitamin D derivatives in the treatment of psoriasis. Summaries of all 5 papers are included here.

Prologue: 2012 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)

The 2012 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) was held in June 2012 in Stockholm, Sweden, and attended by rheumatologists, dermatologists, and representatives of biopharmaceutical companies and patient groups from around the world. In this Prologue we introduce discussions that were held among meeting attendees. Prior to the 2012 meeting, 2 GRAPPA members organized a Fellows Symposium adjacent to the European Academy of Dermatology and Venerology meeting in Verona, where they discussed comorbidities and treatments of patients with psoriasis. The 2012 GRAPPA meeting began with a trainee symposium, where 30 rheumatology fellows and dermatology residents presented their research work. Other presentations and discussions included a review of arthritis mutilans; dermatology issues including screening tools for psoriatic arthritis (PsA) and the instruments to measure psoriasis severity; cardiovascular and other comorbidities of psoriasis and PsA; development of criteria to define inflammatory arthritis, enthesitis, dactylitis, and spondylitis; distinctions between peripheral spondyloarthritis and PsA; the status of an ultrasound outcome measure for dactylitis; and updates on several GRAPPA projects, including a study of biomarkers to predict structural damage in PsA, the ongoing video project, and several education initiatives.

The American Suntanning Association

The American Suntanning Association

A dark papule within an unevenly pigmented plaque

the Department of Otolaryngology and Communicative rvices, University of Mississippi Medical Center, Jackson, d the Department of Dermatology, University of Rochester hool of Medicine and Dentistry, Rochester. rodell is on the speaker’s bureau for Allergan, Galderma, /Graceway Pharmaceuticals, GlaxoSmithKline/Stiefel, Deric, Novartis Pharmaceuticals Corporation, Sanofi-Aventis, edicis, and PharmaDerm, a division of Nycomed US Inc. He s serves as a consultant for Galderma Laboratories, LP, edicis, Dow Pharmaceuticals Sciences, and Promius; has rved on advisory boards for Dow Pharmaceutical Sciences d Nycomed US Inc, and has received grant/research support from Galderma, Abbott Laboratories, and Dow Pharmaceutical Sciences. None of these disclosures are thought to be relevant conflicts of interest. Ms Shlapak and Dr Ward have no conflicts to disclose. Funding sources: None. Reprint requests: Robert T. Brodell, MD, 2500 N State St, Jackson, MS 39216. E-mail: rbrodell@umc.edu. J Am Acad Dermatol 2013;68:e149-50. 0190-9622/$36.00 a 2012 by the American Academy of Dermatology, Inc. http://dx.doi.org/10.1016/j.jaad.2012.10.029

Dermatology conquering distance

4th World Congress on TeledermatologyTbilisi, Georgia, 4–6 October 2012The 4th World Congress of Teledermatology was held from 4–6 October 2012 at Tbilisi, Georgia. George Galdava from the Tbilisi State University, Tbilisi, Georgia and Oleg Kvlividze from the Institute of Dermatology and Venereology, Tbilisi, Georgia, were the Congress President and Secretary, respectively. The Congress theme of ‘dermatology conquering distance’ was exemplified by the speaker delegates from across the globe. Stella Atkins from the University of British Columbia, Canada, started the scientific session with her sterling talk on ‘Automated melanoma diagnosis using a dermoscope attached to a smart phone’. The role of NGOs in the establishing and promotion of telemedicine network today was stressed by Olga Litusi, from Ukraine. Saul Halpern of the British Teledermatology Society expressed that dermatologists in the UK appear to be gradually accepting Teledermatology. The American Academy of Dermatology, African Teledermatology...

The so-called dysplastic nevus is not dysplastic at all

In a recent two-part essay entitled “The dysplastic nevus: from historical perspective to management in the modern era” published in the Journal of American Academy of Dermatology, Duffy and Grossman concluded, following comprehensive literature review, historically, histologically, clinically and molecularly, that the so-called dysplastic nevus is a type of melanocytic nevus and should be managed like other types of melanocytic nevi [1,2]. This reinforces the notion set forth by the late Bernie Ackerman, who asserted more than two decades ago that the so-called dysplastic nevus is the commonest melanocytic nevus in man [3]. Duffy and Grossman acknowledged that the term dysplastic nevus is inappropriate, however, they did not advocate change of the term in these words: “the term ‘dysplastic nevus,’ despite its problems, should not be abandoned—it has become entrenched in our dermatologic language and practice.” [1] We believe the authors underestimated the ramification of continuing the use of an inappropriate term. Historically, the introduction of the term dysplastic nevus was based on an assumption, which has been found to be incorrect. Clark and coworkers believed in the multistep carcinogenesis theory and thought that the lesion under discussion represented an intermediate step between nevus and melanoma. In an article by Clark and coworkers, they expressed this view in these words: “[dysplastic nevi] fit nicely into the schema of progression from hyperplasia to dysplasia to neoplasia that is accepted in many epithelial tumor systems, both experimental and human” [4]. As one examines the literature, there is really no evidence in support of the multistep carcinogenesis theory and there is no intermediate entity between nevus and melanoma [5]. Secondly, although the word “dysplasia” has never been lucidly defined in pathology, whenever the word dysplasia is used in tumor pathology, it generally refers to intraepithelial neoplasia with cytomorphologic features of malignancy, namely, carcinoma in situ lesions, by surgical pathologists. If one looks for an equivalent lesion to the so-called dysplastic (carcinoma in situ) lesions of epithelial tissue in melanocytic neoplasia, melanoma in situ would be the one, not the socalled dysplastic nevus. We have come to know the lesion under discussion is as a variant of melanocytic nevus and the commonest nevus in humans. In other words, it is totally benign and not dysplastic at all, namely, neither an intermediate step between nevus and melanoma nor a carcinoma in situ equivalent. There is no need to excise it surgically unless other than for cosmetic reasons or suspicion of melanoma. However, such a benign lesion has certainly been overtreated since 1980, when the term dysplastic nevus was first introduced [4], due to the continued wrong belief that it represented an intermediate step between nevus and melanoma or a carcinoma in situ equivalent. A survey by Tripp et al found that 86% The so-called dysplastic nevus is not dysplastic at all

Vitiligo: A quantitative analysis of the world research output during 2001-2012

The study aimed to evaluates vitiligo research carried out in different countries of the world during 2001-2012 using bibliometric indicators. Data of the present study has been obtained from Scopus (http://www.scopus) database using the keywords “Alopecia universalis” “onychodystrophy” “Schrander-Stumpel Theunissen Hulsmans syndrome”, “Spastic paraplegia”, “Pigmentation Disorders”, “Hypopigmentation” during the period of study. The study examined the type of documents, country-wise contribution, subject-wise distribution, most productive institutions, most productive authors, highly productive journals and highly cited papers in vitiligo research. A total of 4091 papers were published during 2001-2012 at the annual growth rate of (20.24%). USA is the most productive country which shared (19.41%) of the world publications. India holds 2 nd rank with 388 (9.48%) papers. Overall, 50 or more citations have been witnessed to 207 papers. Germany, France, Spain and Japan activity index has been come down during the period of 2007-2012. However, majority of leading institutions are located in developed countries such as USA, UK, France and Germany. Nevertheless, Postgraduate Institute of Medical Education and Research, Chandigarh has been identifi ed the most productive institution in vitiligo research. Besides this, Karin Uta Schallreuter from University of Bradford is found the most productive author who has contributed 45 articles. Journal of the European Academy of Dermatology and Venereology’ is identifi ed the most productive journal. In the last two decades considerable progress has been made to cope this affl iction, nevertheless scientist are not able to develop a vaccine. It is expected that in near future a vaccine will be available in the market to counter the disease.

The inner golfer in dermatology: “You might as well praise me for not robbing banks”

Luke Lane is a second-year resident in a dermatology residency. He and his fellow residents are already fretting about their preparation for the dermatology certification examination. Passage of the certifying Board examination is a very high-stakes undertaking. Board certification is a requirement of many insurance companies, important for academic stature for university professors, and one of the highest honors that can be achieved by a dermatologist. Historically residents in preceding years who had taken the certifying Board examination had tried to write down as many questions and topics that were on the examination and hand them off to the more junior residents. These ‘‘airplane notes’’ have been a tradition for many decades and have been used as a way to help ensure younger residents that they were well prepared for their examination. Residents have historically known that a significant number of questions on the Board examinations are recycled questions and familiarity with old test questionsconveysasignificantadvantage.Thethird-yearresidentsareLuke’sfriendsandhavepromised to continue this tradition to help their junior residents in their preparation for the Boards. Recently there have been official broadcast e-mail statements from the American Board of Dermatology (ABD) stating that the Board ‘‘has always been opposed to the use of its copyrighted test material, and has openly discussed its opposition to this practice (‘airplane notes’) in the ABD Resident Newsletter and at the Residents in Transition Forum held at the annual American Academy of Dermatology meeting.’’ 1 In addition, residents are required to sign at the start of the Board and practice Board examinations the following statement: ‘‘I agree not to retain the certifying examination of the American Board of Dermatologyinanyformat,nottofurnishanyquestionstoanyentity,andnottodiscussthequestionsor answers with anyone other than the physicians who have taken this examination with me.’’ 1 Luke should: A. Accept the airplane notes from his friends as residents have done for decades before him. To not accept these notes will put him at a major disadvantage when he takes the examination as all his friends at other residencies are continuing this practice. B. Not accept the notes from the graduates who have taken the examination and know that he is following the rules although he is putting himself in a potentially vulnerable position as his peers in his own residency and other residencies may be continuing this tradition. C. Not accept the notes from the graduates who have taken the examination but discuss with them topics that are covered on the examination so that he knows he is preparing correctly. D. Do none of the above.

70th Annual Meeting of the American Academy of Dermatology

70th Annual Meeting of the American Academy of Dermatology