Purpose: Bystander CPR is a critical step in the chain of survival for out of hospital cardiac arrest (OHCA). In North Carolina, survival is estimated to be 12%; 17% of victims receive bystander CPR. Current public knowledge of cardiac arrest and CPR skills are not well described. Methods: We implemented a CPR awareness/ training program during CPR Awareness Week at the Duke Clinical Research Institute (DCRI), a large academic research organization (ARO) traditionally focused on cardiovascular care, to increase awareness of OHCA and CPR. Prior to implementation, employees completed an online survey to gauge prior CPR training, current confidence with CPR, and knowledge of cardiac arrest and CPR skills. The program included expert lectures on cardiac arrest and CPR, a documentary on a Duke patient’s cardiac arrest, as well as a video demonstration (AHA) of Hands-Only CPR. After the education session, trained volunteer instructors taught and evaluated the practical CPR performance skills of each participant. An online post-program survey concluded the program (data collection ongoing). Results: A total of 173 (14.5%) employees completed the pre-program survey. 75% (n=134) of participants were not health care professionals. 67% (n=120) had been previously trained in CPR, of which 60% (n=70) were trained ≥ 5 years ago. Only 16% (n=28) of participants were “very sure” they could perform CPR if needed immediately. Only a minority of respondents were aware that cardiac arrest is associated with very high mortality rates (20%) or that most cardiac arrests occur in the home (21%). 66% of respondents knew that calling 911 is a necessary first step after witnessing a cardiac arrest. While 84% (n=145) respondents knew correct hand placement position for CPR, only 27% (n=47) and 29% (n=54) knew correct compression rate and depth for CPR performance, respectively. In the presence of gasping, only 37% (n=60) knew to start or continue performing CPR on OHCA victims. Conclusion: Cardiac arrest and CPR knowledge are not optimal at our ARO, despite one of our research mission’s to improve emergency cardiovascular care. Community awareness is likely lower than observed at the DCRI. These data highlight opportunities for CPR awareness programs in academic settings and in the community.