Absolute Load Research Articles

Lower body kinetics during the jump shrug: impact of load

The jump shrug (JS) is a weightlifting variation that can be used to teach the power clean (PC), but can also be used to train lower body power itself.1 The JS is ballistic in nature and requires a subject to perform a countermovement with the barbell to the top of the knee, return to the mid-thigh position, and maximally jump while simultaneously shrugging their shoulders.1-3 This PC variation differs from others in that there is a deliberate attempt to jump with the barbell. Despite its potential to produce high amounts of lower body power, only one study has investigated the power development potential of the JS. Suchomel et al.1 demonstrated that the JS produced statistically greater peak force (PF), velocity (PV) and power (PP) than the hang clean (HC) when performed at the same absolute loads. However, their study only examined main effect differences and did not examine the impact that load had on the kinetics associated with power development during the JS.

Knee joint loading during gait in healthy controls and individuals with knee osteoarthritis

People with knee osteoarthritis (OA) are thought to walk with high loads at the knee which are yet to be quantified using modeling techniques that account for subject specific electromyography (EMG) patterns, kinematics and kinetics. The objective was to estimate medial and lateral loading for people with knee OA and controls using an approach that is sensitive to subject specific muscle activation patterns. Sixteen OA and 12 control (C) subjects walked while kinematic, kinetic and EMG data were collected. Muscle forces were calculated using an EMG-Driven model and loading was calculated by balancing the external moments with internal muscle and contact forces. OA subjects walked slower and had greater laxity, static and dynamic varus alignment, less flexion and greater knee adduction moment (KAM). Loading [normalized to body weight (BW)] was no different between the groups but OA subjects had greater absolute medial load than controls and maintained a greater %total load on the medial compartment. These patterns were associated with body mass, sagittal and frontal plane moments, static alignment and close to significance for dynamic alignment. Lateral compartment unloading during mid-late stance was observed in 50% of OA subjects. Loading for control subjects was similar to data from instrumented prostheses. Knee OA subjects had high medial contact loads in early stance and half of the OA cohort demonstrated lateral compartment lift-off. Results suggest that interventions aimed at reducing BW and dynamic malalignment might be effective in reducing medial compartment loading and establishing normal medio-lateral load sharing patterns.

Oxidative in situ deposition of conductive PEDOT:PTSA on textile substrates and their application as textile heating element

Conductive organic polymers are outstanding materials with exciting properties. Besides several other applications – especially in the field of high-performance electric devices and photovoltaic technology – they can be used for the creation of conductive textile materials. Commercial dispersions of such polymers can be applied to textile constructions in a downstream coating process leading to poor add-ons and relatively low conductivity. In contrast, the authors have developed strategies to deposit conductive polymers by an oxidative in situ polymerization directly on the textile surface. Here, poly(3,4-ethylene dioxythiophene) p-toluenesulfonic acid (PEDOT:PTSA) was durably immobilized on a textile polyester fleece following this new approach. The extremely high achievable add-ons lead to extraordinary high-conductive textiles with surface resistances down to 10Ω/sq. Such a way finished textiles can be used as high-performance textile heating elements. For example, by applying a standard voltage of 24V temperatures up to 170°C are practicable. Moreover, the desired temperature is easily adjustable by the absolute load and the applied voltage. These conductive textiles can be used, e.g., in carpets, electric blankets or automotive seat heaters.

High HBV Viral Loads in HIV-Infected Pregnant Women at a Tertiary Hospital, South Africa

High HBV Viral Loads in HIV-Infected Pregnant Women at a Tertiary Hospital, South Africa

Obesity-related differences in muscular capacity during sustained isometric exertions

Over one-third of the world adult population is overweight or obese, and the prevalence continues to increase. Obesity is a risk factor for injury, and the growing prevalence may be associated with increases in the future incidence and cost of injuries. In this study, we examined obesity-related differences in muscular capacity during sustained isometric exertions involving hand grip, shoulder flexion, and trunk extension. Thirty-six young individuals who were obese or not obese (aged 18–29) completed these exertions at fixed levels of absolute loads involving low-moderate levels of effort. Individuals who were obese had an overall ∼20% higher absolute strength, but ∼20% lower relative strength. These differences were most evident in the hand grip and shoulder exertions. Parameters of fitted exponential relationships between endurance time and task demands (as a percentage of strength) were similar in both groups. Perceptual and performance responses were also consistent between groups. Accordingly, we conclude that obesity may not substantially influence muscular capacity for these tasks.

The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period

Mechanical loading of human tendon stimulates collagen synthesis, but the relationship between acute loading responses and training status of the tendon is not clear. We tested the effect of prolonged load deprivation on the acute loading-induced collagen turnover in human tendons, by applying the same absolute load to a relative untrained Achilles tendon (2-week immobilization period prior to acute loading) and a habitually loaded contra-lateral Achilles tendon, respectively, within the same individuals. Eight untrained, healthy males had one lower limb totally immobilized for 2weeks, whereas the contra-lateral leg was used habitually. Following the procedure both Achilles tendons and calf muscles were loaded with the same absolute load during a 1-h treadmill run. Tissue collagen turnover was measured by microdialysis performed post-immobilization but pre-exercise around both Achilles tendons and compared to values obtained by 72-h post-exercise. Power Doppler was used to monitor alterations in intratendinous blood flow velocity of the Achilles tendon and MRI used to quantitate changes in tendon cross-section area. Acute loading resulted in an increased collagen synthesis 72h after the run in both Achilles tendons (p<0.05) with no significant difference. No signs of acute tendon overloading were demonstrated by Power Doppler, and tendon cross-section area did not change as a result of immobilization and reloading. The present study indicates that 2weeks of tendon load deprivation is not sufficient to affect the normal adaptive response to loading determined as increased collagen synthesis of peritendinous Achilles tendon tissue in humans.

Evaluation of muscle oxygenation by near-infrared spectroscopy in patients with Becker muscular dystrophy

Several authors have reported alterations in vasodilation during effort in patients with dystrophinopathies, in which a lack of neuronal NO synthase is thought to lead to functional muscle ischemia. In order to determine changes in muscle oxygenation during effort in patients with Becker muscular dystrophy (BMD) and assess the parameters’ links with disease severity and functional status, 10 BMD patients and 10 age-matched controls performed isokinetic, constant-load knee extension exercises at (i) 20% of their extensors’ peak torque (i.e. the same relative load) and (ii) the same absolute load (20Nm). Muscle oxygenation was evaluated noninvasively using near-infrared spectroscopy (NIRS), with the time course of deoxygenation as the main criterion. As expected, BMD patients displayed a lower peak torque than controls (−62%). During both types of exercise, initial muscle deoxygenation was faster (by 27–41%) in BMD patients than in controls. Greater disease severity (according to the Motor Function Measure) and functional impairment (walking endurance) were associated with a faster second deoxygenation phase (τ). The validity and relevance of muscle deoxygenation parameters and the alteration of vasodilatation by nNOS deficiency in dystrophinopathies should be assessed by further studies.

The Nutrient-Load Hypothesis: Patterns of Resource Limitation and Community Structure Driven by Competition for Nutrients and Light

Resource competition theory predicts that the outcome of competition for two nutrients depends on the ratio at which these nutrients are supplied. Yet there is considerable debate whether nutrient ratios or absolute nutrient loads determine the species composition of phytoplankton and plant communities. Here we extend the classical resource competition model for two nutrients by including light as additional resource. Our results suggest the nutrient-load hypothesis, which predicts that nutrient ratios determine the species composition in oligotrophic environments, whereas nutrient loads are decisive in eutrophic environments. The underlying mechanism is that nutrient enrichment shifts the species interactions from competition for nutrients to competition for light, which favors the dominance of superior light competitors overshadowing all other species. Intermediate nutrient loads can generate high biodiversity through a fine-grained patchwork of two-species and three-species coexistence equilibria. Depending on the species traits, however, competition for nutrients and light may also produce multiple alternative stable states, suppressing the predictability of the species composition. The nutrient-load hypothesis offers a solution for several discrepancies between classical resource competition theory and field observations, explains why eutrophication often leads to diversity loss, and provides a simple conceptual framework for patterns of biodiversity and community structure observed in nature.

Neuromuscular and cardiovascular responses of Royal Marine recruits to load carriage in the field

Cardiovascular and neuromuscular responses of 12 male Royal Marine recruits (age 22 ± 3 years, body mass 80.7 ± 6.8 kg, V˙O2max 52.3 ± 2.7 ml kg−1 min−1) were measured during 19.3 km of load carriage walking at 4.2 km h−1 and carrying 31.0 kg. Heart rate during load carriage was 145 ± 10 beats·min−1 (64 ± 5 %HRR) and showed a negative relationship with body mass (r = −0.72, P = 0.009) but no relationship with V˙O2max (ml kg−1 min−1; r = −0.40, P = 0.198). Load carriage caused a decrease in vertical jump height (8 ± 9%) and power (5 ± 5%) (P < 0.001). Change in vertical jump power showed a positive relationship with body mass (r2 = 0.40, P = 0.029) but no relationship to V˙O2max (ml kg−1 min−1; r2 = 0.13, P = 0.257). In conclusion, load carriage caused a reduction in vertical jump performance (i.e. decreased neuromuscular function). Lighter individuals were disadvantaged when carrying absolute loads, as they experienced higher cardiovascular strain and greater decreases in neuromuscular function.

Benefits for bone from resistance exercise and nutrition in long-duration spaceflight: Evidence from biochemistry and densitometry

Exercise has shown little success in mitigating bone loss from long-duration spaceflight. The first crews of the International Space Station (ISS) used the "interim resistive exercise device" (iRED), which allowed loads of up to 297 lb(f) (or 1337 N) but provided little protection of bone or no greater protection than aerobic exercise. In 2008, the Advanced Resistive Exercise Device (ARED), which allowed absolute loads of up to 600 lb(f) (1675 N), was launched to the ISS. We report dietary intake, bone densitometry, and biochemical markers in 13 crewmembers on ISS missions from 2006 to 2009. Of these 13, 8 had access to the iRED and 5 had access to the ARED. In both groups, bone-specific alkaline phosphatase tended to increase during flight toward the end of the mission (p = 0.06) and increased 30 days after landing (p < 0.001). Most markers of bone resorption were also increased in both groups during flight and 30 days after landing (p < 0.05). Bone densitometry revealed significant interactions (time and exercise device) for pelvis bone mineral density (BMD) and bone mineral content (p < 0.01), hip femoral neck BMD (p < 0.05), trochanter BMD (p < 0.05), and total hip BMD (p < 0.05). These variables were unchanged from preflight only for ARED crewmembers, who also returned from flight with higher percent lean mass and lower percent fat mass. Body mass was unchanged after flight in both groups. All crewmembers had nominal vitamin D status (75 ± 17 nmol/L) before and during flight. These data document that resistance exercise, coupled with adequate energy intake (shown by maintenance of body mass determined by dual-energy X-ray absorptiometry [DXA]) and vitamin D, can maintain bone in most regions during 4- to 6-month missions in microgravity. This is the first evidence that improving nutrition and resistance exercise during spaceflight can attenuate the expected BMD deficits previously observed after prolonged missions.

Optimization of the twists of double-twisted high-melting fibers

Ceramic fibers produced in the form of multi-filament filament fibers are not strong enough to be used directly as a structural material. Factorial experiment planning is used to obtain a regression equation that describes the dependence of the absolute breaking load of a filament with a linear density of 100 tex on the degree of twisting when the initial 10-tex filament is doubled to form two strands and then five strands. The optimum degree of twisting is determined through the use of evolutionary planning.

Culture-based detection of methicillin-resistant Staphylococcus aureus by a network of European laboratories: an external quality assessment study

Twenty-three hospital laboratories from Europe and Israel participated in an external quality assessment (EQA) of the culture-based detection of methicillin-resistant Staphylococcus aureus (MRSA). Participants also reported the MRSA prevalence in clinical cultures and patient screening specimens, as well as the MRSA screening practices employed at their hospitals. An EQA panel of 18 samples consisting of two MRSA harbouring SCCmec IV and I, and one strain each of methicillin-resistant coagulase-negative S. epidermidis, methicillin-sensitive S. aureus and Escherichia coli as pure strains or in mixtures at 10(7)-1 cfu absolute loads was analysed by the 23 participants. Seventeen (74%) participants identified 17 or more samples correctly. Of these, 15 (88%) utilised a chromogenic medium alone (ChromID, bioMérieux; BBL CHROMagar, BD Diagnostics; MRSA Select, Bio-Rad Laboratories) or combined with a conventional medium and up to three confirmatory tests. Proportions of MRSA among S. aureus isolated from clinical cultures varied widely, even among hospitals within countries, ranging from 11-20% to 61-70%. MRSA carriage rates were less variable (0-20%) between countries. Almost all participants (n=22, 96%) screened patients for MRSA carriage during 2009-2010, of which 15 (68%) screened intensive care unit (ICU) patients alone or combined with other targeted high-risk groups, and 10 (45%) combined nasal screening with another body site.

Digital PCR provides absolute quantitation of viral load for an occult RNA virus

Using a multiplexed LNA-based Taqman assay, RT-digital PCR (RT-dPCR) was performed in a prefabricated microfluidic device that monitored absolute viral load in native and immortalized cell lines, overall precision of detection, and the absolute detection limit of an occult RNA virus GB Virus Type C (GBV-C). RT-dPCR had on average a 10% lower overall coefficient of variation (CV, a measurement of precision) for viral load testing than RT-qPCR and had a higher overall detection limit, able to quantify as low as three 5'-UTR molecules of GBV-C genome. Two commercial high-yield in vitro transcription kits (T7 Ribomax Express by Promega and Ampliscribe T7 Flash by Epicentre) were compared to amplify GBV-C RNA genome with T7-mediated amplification. The Ampliscribe T7 Flash outperformed the T7 Ribomax Express in yield of full-length GBV-C RNA genome. THP-1 cells (a model of monocytic derived cells) were transfected with GBV-C, yielding infectious virions that replicated over a 120h time course and could be infected directly. This study provides the first evidence of GBV-C replication in monocytic derived clonal cells. Thus far, it is the only study using a microfluidic device that measures directly viral load of mammalian RNA virus in a digital format without need for a standard curve.

Strength and power training did not modify cardiovascular responses to aerobic exercise in elderly subjects

Resistance training increases muscle strength in older adults, decreasing the effort necessary for executing physical tasks, and reducing cardiovascular load during exercise. This hypothesis has been confirmed during strength-based activities, but not during aerobic-based activities. This study determined whether different resistance training regimens, strength training (ST, constant movement velocity) or power training (PT, concentric phase performed as fast as possible) can blunt the increase in cardiovascular load during an aerobic stimulus. Older adults (63.9 ± 0.7 years) were randomly allocated to: control (N = 11), ST (N = 13, twice a week, 70-90% 1-RM) and PT (N = 15, twice a week, 30-50% 1-RM) groups. Before and after 16 weeks, oxygen uptake (VO(2)), systolic blood pressure (SBP), heart rate (HR), and rate pressure product (RPP) were measured during a maximal treadmill test. Resting SBP and RPP were similarly reduced in all groups (combined data = -5.7 ± 1.2 and -5.0 ± 1.7%, respectively, P < 0.05). Maximal SBP, HR and RPP did not change. The increase in measured VO(2), HR and RPP for the increment in estimated VO(2) (absolute load) decreased similarly in all groups (combined data = -9.1 ± 2.6, -14.1 ± 3.9, -14.2 ± 3.0%, respectively, P < 0.05), while the increments in the cardiovascular variables for the increase in measured VO(2) did not change. In elderly subjects, ST and PT did not blunt submaximal or maximal HR, SBP and RPP increases during the maximal exercise test, showing that they did not reduce cardiovascular stress during aerobic tasks.

Cytomegalovirus viraemia in the modern antiretroviral era*

Cytomegalovirus viraemia in the modern antiretroviral era*

Cadmium exposure route affects antioxidant responses in the mayfly Centroptilum triangulifer

Aquatic organisms accumulate metals directly from water and from their diets. Exposure to metals is known to generate oxidative stress in living organisms and this stress may be ameliorated via activation of antioxidant enzymes and non-enzymatic antioxidants. To determine if antioxidant physiology is dependent on Cd exposure route in the mayfly Centroptilum triangulifer, we exposed larvae to environmentally relevant concentrations of Cd from isolated dissolved or dietary exposure routes to achieve comparable tissue concentrations. Dissolved Cd had no effect on the antioxidant enzymes examined. However, dietary Cd significantly suppressed catalase and superoxide dismutase activities, and decreased concentrations of the reduced (active) form of glutathione in C. triangulifer larvae. These findings suggest that dietary Cd is potentially more toxic than aqueously derived Cd in this mayfly. We further examined the effect of dietary Cd tissue loading rates on antioxidant enzyme suppression and found that absolute tissue load appeared more important than loading rate. These results may help explain why insects are routinely unresponsive to dissolved metal exposures in the laboratory, yet highly responsive to metal pollution in nature.

Physical Fitness Of High Performance Swimmers With Mild Intellectual Disability

INTRODUCTION: There is a growing number of swimmers with mild (IQ<75) Intellectual Disability (ID) competing internationally. Although many of these swimmers train intensively, not much is known about the physical fitness of this population of swimmers or how to grade their performance. PURPOSE: To determine some physical characteristic of ID swimmers and compare them with able bodied (AB) swimmers competing at European level, and also to compare finalist and non-finalist at an international competition for ID swimmers. METHODS: Thirty-one male and 36 female swimmers at the Global Games 2004 (World Championships) were tested with Eurofit test battery for general fitness and with a swim-specific test battery of 7 body structure, 7 flexibility, and 4 static strength measures. Informed consent was given. RESULTS: There were nearly no significant differences between finalists and non-finalist in swim-specific body build, flexibility or strength. Male finalists were taller, had wider shoulders and larger forearms (p< 0.05). However, compared to European level elite AB swimmers in both men and women, ID swimmers scored on the average below the 40th percentile in 5 of the 7 body structure measures, and below the 35th percentile in all strength measures. The mean scores for all strength measures were actually only at the 18th percentile for men and 11th for women. Global Games swimmers were also short and relatively heavy. Both male and females, scored only above the 50th percentile in 3 of the 8 flexibility measures. CONCLUSION: Among ID swimmers, finalist and non-finalists differ only slightly in body structure, and not at all in flexibility or strength. Although the absolute training load of ID swimmers might not differ from that of AB swimmers, their performance is worse and their scores on body structure, flexibility, and strength measures are much lower. Better understanding of ID swimmers training needs is required.

Strength Testing and Training of Rowers

In the quest to maximize average propulsive stroke impulses over 2000-m racing, testing and training of various strength parameters have been incorporated into the physical conditioning plans of rowers. Thus, the purpose of this review was 2-fold: to identify strength tests that were reliable and valid correlates (predictors) of rowing performance; and, to establish the benefits gained when strength training was integrated into the physical preparation plans of rowers. The reliability of maximal strength and power tests involving leg extension (e.g. leg pressing) and arm pulling (e.g. prone bench pull) was high (intra-class correlations 0.82-0.99), revealing that elite rowers were significantly stronger than their less competitive peers. The greater strength of elite rowers was in part attributed to the correlation between strength and greater lean body mass (r = 0.57-0.63). Dynamic lower body strength tests that determined the maximal external load for a one-repetition maximum (1RM) leg press (kg), isokinetic leg extension peak force (N) or leg press peak power (W) proved to be moderately to strongly associated with 2000-m ergometer times (r = -0.54 to -0.68; p < 0.05). Repetition tests that assess muscular or strength endurance by quantifying the number of repetitions accrued at a fixed percentage of the strength maximum (e.g. 50-70% 1RM leg press) or set absolute load (e.g. 40 kg prone bench pulls) were less reliable and more time consuming when compared with briefer maximal strength tests. Only leg press repetition tests were correlated with 2000-m ergometer times (e.g. r = -0.67; p < 0.05). However, these tests differentiate training experience and muscle morphology, in that those individuals with greater training experience and/or proportions of slow twitch fibres performed more repetitions. Muscle balance ratios derived from strength data (e.g. hamstring-quadriceps ratio <45% or knee extensor-elbow flexor ratio around 4.2 ± 0.22 to 1) appeared useful in the pathological assessment of low back pain or rib injury history associated with rowing. While strength partially explained variances in 2000-m ergometer performance, concurrent endurance training may be counterproductive to strength development over the shorter term (i.e. <12 weeks). Therefore, prioritization of strength training within the sequence of training units should be considered, particularly over the non-competition phase (e.g. 2-6 sets × 4-12 repetitions, three sessions a week). Maximal strength was sustained when infrequent (e.g. one or two sessions a week) but intense (e.g. 73-79% of maximum) strength training units were scheduled; however, it was unclear whether training adaptations should emphasize maximal strength, endurance or power in order to enhance performance during the competition phase. Additionally, specific on-water strength training practices such as towing ropes had not been reported. Further research should examine the on-water benefits associated with various strength training protocols, in the context of the training phase, weight division, experience and level of rower, if limitations to the reliability and precision of performance data (e.g. 2000-m time or rank) can be controlled. In conclusion, while positive ergometer time-trial benefits of clinical and practical significance were reported with strength training, a lack of statistical significance was noted, primarily due to an absence of quality long-term controlled experimental research designs.

Small scale impact of gas technologies on electric load management – μCHP & hybrid heat pump

To face winter electricity peaking issues the authors proposes an analysis of the potential of distributed gas technologies for demand side management. This impact has to be analysed at small scale before any large scale extrapolation. Bi-energy technologies (gas and electricity) are a path to transfer loads from one system to another. Indeed, the flexible gas infrastructure adapts to load while electricity demand variations cause risk of black-out. The impacts of two hybrid technologies are studied at transformer level with 1-min experimental load profiles of 40 dwellings equipped with micro Combined Heat and Power (μCHP) boilers over a year in France. An absolute peak load reduction by 17% at small scale is found. Different technology mixes are then simulated to assess the effect on local infrastructure. Finally a methodology for temperature dependence analysis of load is used to assess different potential benefits of gas technologies.

Safety and Efficacy of Supervised Strength Training Adopted in Pregnancy

Describe safety and efficacy of a supervised, low-to-moderate intensity strength training program adopted during pregnancy among women at increased risk for back pain. 32 women adopted strength training twice per week for 12 weeks. Data on musculoskeletal injuries, symptoms, blood pressure, and the absolute external load used for 5 of 6 exercises were obtained during each session. A submaximal lumbar extension endurance exercise test was performed at weeks 5, 10, and 13. The mean (± SD) exercise session attendance rate was 80.5% (± 11.3%). No musculoskeletal injuries occurred. Potentially adverse symptoms (eg, dizziness) were infrequent (2.1% of sessions). Repeated-measures ANOVA showed large increases in the external load across 12 weeks (all P values < .001) and the percentage increases in external load from weeks 1 to 12 were 36% for leg press, 39% for leg curl, 39% for lat pull down, 41% for lumbar extension and 56% for leg extension. Training was associated with a 14% increase in lumbar endurance. Blood pressure was unchanged following acute exercise sessions and after 12 weeks of exercise training. The adoption of a supervised, low-to-moderate intensity strength training program during pregnancy can be safe and efficacious for pregnant women.