Absolute Intensity Research Articles

Low Geomagnetic Field Paleointensity on the Permian–Triassic Boundary from Study of the Kuznetsk Basin Traps (Southern Siberia)

Abstract ––Here we report the first data on the absolute intensity value of the geomagnetic field on the Permian–Triassic boundary from basalts of the Kuznetsk basin. The latter are considered as one of the manifestations of the initial stage of trap magmatism during the formation of the Siberian large igneous province. The good preservation of information on the ancient geomagnetic field in the Mal’tsevskaya Formation basalts is due to the presence of small single domain and pseudo-single domain grains of primary magmatic titanomagnetite in the groundmass. The paleointensity values obtained following the Thellier-Coe method correspond to the generally accepted criteria of reliability and indicate that the geomagnetic field intensity during the formation of the Kuznetsk basin traps on the Permian–Triassic boundary was almost an order of magnitude lower than the present-day one. Moreover, the mean values of the virtual dipole moment for the Kozhukhta and the Vlasov units in the lower and middle Mal’tsevskaya Formation ((1.9 ± 0.6) ⋅ 1022 A ⋅ m2 and (1.1 ± 0.7) ⋅ 1022 A ⋅ m2, respectively) are in good alignment with determinations of the paleointensity during the accumulation of the Ivakinsky Formation of the Norilsk Region in the Siberian province, which confirms the accuracy of traditional regional correlations.

Short-lived Alpha Power Suppression Induced by Low-intensity Arrhythmic rTMS

This study was conducted to provide a better understanding of the role of electric field strength in the production of aftereffects in resting state scalp electroencephalography by repetitive transcranial magnetic stimulation (rTMS) in humans. We conducted two separate experiments in which we applied rTMS over the left parietal-occipital region. Prospective electric field simulation guided the choice of the individual stimulation intensities. In the main experiment, 16 participants received rhythmic and arrhythmic rTMS bursts at between ca. 20 and 50 mv/mm peak absolute electric field intensities. In the control experiment, another group of 16 participants received sham rTMS. To characterize the aftereffects, we estimated the alpha power (8–14 Hz) changes recorded in the inter-burst intervals, i.e., from 0.2 to 10 s after rTMS. We found aftereffects lasting up to two seconds after stimulation with ca. 35 mV/mm. Relative to baseline, alpha power was significantly reduced by the arrhythmic protocol, while there was no significant change with the rhythmic protocol. We found no significant long-term, i.e., up to 10-second, differences between the rhythmic and arrhythmic stimulation, or between the rhythmic and sham protocols. Weak arrhythmic rTMS induced short-lived alpha suppression during the inter-burst intervals.

Blood pressure responses to static and dynamic knee extensor exercise between sexes: Role of absolute contraction intensity

Males have larger blood pressure (BP) responses to relative intensity static handgrip exercise compared to females. Controlling for maximal voluntary contraction (MVC) absolute strength abolishes these differences. Whether similar observations exist during large muscle mass exercise or dynamic contractions remain unknown. BP, heart rate, muscle oxygenation (near-infrared spectroscopy), and rectus femoris electromyography (EMG) were recorded in 28 males and 17 females during 10% and 30% MVC static (120s) and isokinetic dynamic (180s; 1:2 work-to-rest ratio; angular velocity: 60º/s) knee extensor exercise. At baseline and during exercise, continuous BP and heart rate were measured using finger photoplethysmography and single-lead electrocardiography, respectively. MVC, as well as all submaximal exercise testing, was measured and performed on a dynamometer at 80⁰ of knee flexion, and voluntary activation was assessed using the interpolated twitch technique, with ≥90% voluntary activation of the knee extensors set as the acceptable activation threshold. Static and dynamic exercises were completed on separate visits, in a randomized order. The change from baseline of each variable was calculated for every 30 s during each submaximal test. Sex differences were then examined with and without statistical adjustment of MVC using analyses of covariance (ANCOVA). The males were taller and heavier than the females and had higher resting systolic BP (all P<0.05), while BMI, resting diastolic and mean arterial BP, and heart rate were similar between sexes (all P>0.05). Knee extensor MVC was higher in males than females (165 ± 40 vs. 94 ± 22 Nm, P<0.0001). Males had larger systolic BP responses (interaction, P<0.001) and muscle deoxygenation (interaction, P<0.01) than females during 10% static exercise, with no difference in EMG (interaction, P=0.73). Peak systolic BP was correlated to MVC (r=0.53, P=0.0002), and adjustment for MVC abolished sex differences in systolic BP (interaction, P=0.5). BP, heart rate, muscle oxygenation/deoxygenation, and EMG responses did not differ between sexes during 30% static exercise (interaction, All P>0.2), including following adjustment for MVC (All P>0.1). Males had larger systolic BP responses during dynamic exercise at 10% and 30% (interaction, Both P=0.01), which were abolished after adjustment for MVC (interaction, Both P>0.08). Systolic BP responses at 180s were correlated with MVC and stroke volume responses during 10% (r=0.31, P=0.04; r=0.61, P<0.0001, respectively) and 30% (r=0.4, P=0.007; r=0.59, P<0.0001, respectively). In conclusion, MVC can influence systolic BP responses to 10% but not 30% MVC static, as well as 10% and 30% MVC dynamic knee extensor exercise. MVC should be considered when comparing BP responses between males and females. Finally, the mechanisms mediating the larger pressor responses in stronger individuals across different exercise modalities warrant further investigation.

A single session of high‐intensity interval exercise in hypoxia did not change mitochondrial respiration or content in human skeletal muscle biopsies

Both high-intensity interval exercise (HIIE) and hypoxia have been suggested to affect mitochondria. However, it is not yet fully elucidated how a single session of HIIE in hypoxia affects mitochondrial respiration and content in human skeletal muscle. In this current study, we investigated the effects of a single session of HIIE combined with simulated hypoxia (3200 m, oxygen fraction of 14%) on mitochondrial respiration and content. We hypothesized that HIIE in hypoxia would induce substantial changes in mitochondrial respiration, but not in mitochondrial content. Ten healthy male participants (age, 28 ± 5 years; BMI, 26.0 ± 3.4) were recruited and completed three HIIE sessions (six 4-minute exercise bouts, separated by 2 minutes of resting) in a random order, separated by at least one week. Exercise sessions include an HIIE in hypoxia (88.4% of peak oxygen uptake (VO2peak) determined in hypoxia), an HIIE in normoxia matched for relative intensity (88.7% of VO2peak determined in normoxia), and an HIIE in normoxia matched for absolute intensity (74.1% of VO2peak determined in normoxia). Skeletal muscle samples were collected prior to, 3 hours, and 24 hours post-exercise to determine mitochondrial respiration and content. Hypoxia decreased VO2peak (by 20.2 ± 9.1%, p < 0.01), peak power output (PPO, by 9.4 ± 2.1%, p<0.01), and lactate threshold (LT, by 13.1 ± 3.0%, p<0.01). In the skeletal muscle biopsies, mitochondrial respiration, measured by Oroboros O2k with high-resolution respirometry, was similar among the three conditions prior to the HIIE interventions (p > 0.05) and remained unchanged both 3 and 24 hours after HIIE interventions performed in different conditions (p > 0.05). Citrate synthase activity, as a marker of mitochondrial content, did not differ prior to, or 3 and 24 hours after HIIE interventions among the three conditions (p > 0.05) . In conclusion, a single session of HIIE in hypoxia did not alter mitochondrial respiration and content. Gene expression and protein content of mitochondrial biogenesis markers are currently being analyzed.

Seasonal training and match load and micro-cycle periodization in male Premier League academy soccer players

ABSTRACT We quantified on pitch external loading of English Premier League (EPL) academy soccer players (n=76; U12-U18 age groups) over an entire competitive season. Mean accumulative weekly duration and total distance, respectively, was similar in the U12 (329±29 min; 19.9±2.2 km), U13 (323±29 min; 20.0±2.0 km) and U14 (339±25 min; 21.7±2.0 km; P>0.05 for all comparisons) age-groups, though all teams were less than U15 (421±15 min; 26.2±2.1 km), U16 (427±20 min; 25.9±2.5 km) and U18 (398±30 min; 26.1±2.6 km) players (P<0.05 for all comparisons). Mean weekly high-speed running and sprint distance was not different between U12 (220±95 m and 6±9 m respectively), U13 (331±212 m and 6±27 m) and U14 (448±193 m and 21±29 m) age-groups (P>0.05 for all pairwise comparisons) though all squads were less than U15 (657±242 m and 49±98 m), U16 (749±152 m and 95±55 m) and U18 (979±254 m and 123±56 m) age-groups (P<0.05 for all pairwise comparisons). Data demonstrate that absolute weekly training volume in EPL academy soccer players increases throughout the academy pathway. Furthermore, although U16-U18 players are capable of achieving similar training and match volumes as previously reported in adult EPL players, they do not yet achieve the absolute intensities of adult EPL players.

Quantitative and Qualitative Running Gait Analysis through an Innovative Video-Based Approach.

Quantitative and qualitative running gait analysis allows the early identification and the longitudinal monitoring of gait abnormalities linked to running-related injuries. A promising calibration- and marker-less video sensor-based technology (i.e., Graal), recently validated for walking gait, may also offer a time- and cost-efficient alternative to the gold-standard methods for running. This study aim was to ascertain the validity of an improved version of Graal for quantitative and qualitative analysis of running. In 33 healthy recreational runners (mean age 41 years), treadmill running at self-selected submaximal speed was simultaneously evaluated by a validated photosensor system (i.e., Optogait—the reference methodology) and by the video analysis of a posterior 30-fps video of the runner through the optimized version of Graal. Graal is video analysis software that provides a spectral analysis of the brightness over time for each pixel of the video, in order to identify its frequency contents. The two main frequencies of variation of the pixel’s brightness (i.e., F1 and F2) correspond to the two most important frequencies of gait (i.e., stride frequency and cadence). The Optogait system recorded step length, cadence, and its variability (vCAD, a traditional index of gait quality). Graal provided a direct measurement of F2 (reflecting cadence), an indirect measure of step length, and two indexes of global gait quality (harmony and synchrony index). The correspondence between quantitative indexes (Cadence vs. F2 and step length vs. Graal step length) was tested via paired t-test, correlations, and Bland–Altman plots. The relationship between qualitative indexes (vCAD vs. Harmony and Synchrony Index) was investigated by correlation analysis. Cadence and step length were, respectively, not significantly different from and highly correlated with F2 (1.41 Hz ± 0.09 Hz vs. 1.42 Hz ± 0.08 Hz, p = 0.25, r2 = 0.81) and Graal step length (104.70 cm ± 013.27 cm vs. 107.56 cm ± 13.67 cm, p = 0.55, r2 = 0.98). Bland–Altman tests confirmed a non-significant bias and small imprecision between methods for both parameters. The vCAD was 1.84% ± 0.66%, and it was significantly correlated with neither the Harmony nor the Synchrony Index (0.21 ± 0.03, p = 0.92, r2 = 0.00038; 0.21 ± 0.96, p = 0.87, r2 = 0.00122). These findings confirm the validity of the optimized version of Graal for the measurement of quantitative indexes of gait. Hence, Graal constitutes an extremely time- and cost-efficient tool suitable for quantitative analysis of running. However, its validity for qualitative running gait analysis remains inconclusive and will require further evaluation in a wider range of absolute and relative running intensities in different individuals.

Parity-violation effects in the vibrational spectra of CHFClBr and CDFClBr

Relativistic four-component electronic structure calculations at the density functional level have been carried out to describe parity-violation (PV) energy shifts to the total electronic energy for the chiral molecule CHFClBr. An $n$-mode ($n=3,4$) expansion of the complete potential energy surface at the explicitly correlated coupled-cluster level has been used for the vibrational analysis of PV effects for CHFClBr and CDFClBr. The vibrational spectrum and corresponding absolute intensities for fundamental, overtone, and combination band transitions obtained from a variational configuration interaction treatment are in excellent agreement with experimental data and the most accurate so far obtained. The results show that a 3-mode expansion is sufficient for the vibrational analysis. The PV energy shifts for the fundamental, overtone, and combination bands are all in the mHz region. The data provided will be useful for future detection of PV in chiral molecules.

Temperature dependence of optical centers in Ib diamond characterized by photoluminescence spectra

The optical properties of defects in Ib diamond prepared by Chemical Vapor Deposition (CVD) and High Pressure High Temperature (HPHT) methods are studied by photoluminescence in a temperature range of 77– 297 K. The temperature dependence of color centers in diamond of 2.65 eV center, NV0, NV-, SiV-, 3H is studied. The zero-phonon line (ZPL) shift, intensity and full width at half maxima (FWHM) have a strong temperature dependence. The study shows that, due to the expansion of the lattice and the enhancement of the electron-phonon coupling strength, the ZPL shift can be described by the modified Varshni model which shows great potential in temperature sensing. The FWHM of ZPL matches a cubic function of temperature, this model can be employed to well describe the broadening of ZPLs in the defect-rich diamond. And the thermal quenching of absolute PL intensity can be described by the Arrhenius equation. Meanwhile, the difference of variable PL signal between CVD and HPHT samples is analyzed.

Sensing with Chirality-Pure Near-Infrared Fluorescent Carbon Nanotubes.

Semiconducting single-wall carbon nanotubes (SWCNTs) fluoresce in the near-infrared (NIR) region, and the emission wavelength depends on their chirality (n,m). Interactions with the environment affect the fluorescence and can be tailored by functionalizing SWCNTs with biopolymers such as DNA, which is the basis for fluorescent biosensors. So far, such biosensors have been mainly assembled from mixtures of SWCNT chiralities with large spectral overlap, which affects sensitivity as well as selectivity and prevents multiplexed sensing. The main challenge to gain chirality-pure sensors has been to combine approaches to isolate specific SWCNTs and generic (bio)functionalization approaches. Here, we created chirality-pure SWCNT-based NIR biosensors for important analytes such as neurotransmitters and investigated the effect of SWCNT chirality/handedness as well as long-term stability and sensitivity. For this purpose, we used aqueous two-phase extraction (ATPE) to gain chirality-pure (6,5)-, (7,5)-, (9,4)-, and (7,6)-SWCNTs (emission at ∼990, 1040, 1115, and 1130 nm, respectively). An exchange of the surfactant sodium deoxycholate (DOC) to specific single-stranded (ss)DNA sequences yielded monochiral sensors for small analytes (dopamine, riboflavin, ascorbic acid, pH). DOC residues impaired sensitivity, and therefore substantial removal was necessary. The assembled monochiral (6,5)-SWCNTs were up to 10 times brighter than their nonpurified counterparts, and the ssDNA sequence determined the absolute fluorescence intensity as well as colloidal (long-term) stability and selectivity for the analytes. (GT)40-(6,5)-SWCNTs displayed the maximum fluorescence response to the neurotransmitter dopamine (+140%, Kd = 1.9 × 10-7 M) and a long-term stability of >14 days. The specific ssDNA sequences imparted selectivity to the analytes mostly independent of SWCNT chirality and handedness of (±) (6,5)-SWCNTs, which allowed a predictable design. Finally, multiple monochiral/single-color SWCNTs were combined to achieve ratiometric/multiplexed sensing of the important analytes dopamine, riboflavin, H2O2, and pH. In summary, we demonstrated the assembly, characteristics, and potential of monochiral (single-color) SWCNTs for NIR fluorescence sensing applications.

Combining Events and Frames Using Recurrent Asynchronous Multimodal Networks for Monocular Depth Prediction

Event cameras are novel vision sensors that report per-pixel brightness changes as a stream of asynchronous “events”. They offer significant advantages compared to standard cameras due to their high temporal resolution, high dynamic range and lack of motion blur. However, events only measure the varying component of the visual signal, which limits their ability to encode scene context. By contrast, standard cameras measure absolute intensity frames, which capture a much richer representation of the scene. Both sensors are thus complementary. However, due to the asynchronous nature of events, combining them with synchronous images remains challenging, especially for learning-based methods. This is because traditional recurrent neural networks (RNNs) are not designed for asynchronous and irregular data from additional sensors. To address this challenge, we introduce Recurrent Asynchronous Multimodal (RAM) networks, which generalize traditional RNNs to handle asynchronous and irregular data from multiple sensors. Inspired by traditional RNNs, RAM networks maintain a hidden state that is updated asynchronously and can be queried at any time to generate a prediction. We apply this novel architecture to monocular depth estimation with events and frames where we show an improvement over state-of-the-art methods by up to 30% in terms of mean absolute depth error. To enable further research on multimodal learning with events, we release EventScape, a new dataset with events, intensity frames, semantic labels, and depth maps recorded in the CARLA simulator.

Track Dependence of Tropical Cyclone Intensity Forecast Errors in the COAMPS-TC Model

AbstractThis study examines the dependence of tropical cyclone (TC) intensity forecast errors on track forecast errors in the Coupled Ocean–Atmosphere Mesoscale Prediction System for Tropical Cyclones (COAMPS-TC) model. Using real-time forecasts and retrospective experiments during 2015–18, verification of TC intensity errors conditioned on different 5-day track error thresholds shows that reducing the 5-day track errors by 50%–70% can help reduce the absolute intensity errors by 18%–20% in the 2018 version of the COAMPS-TC model. Such impacts of track errors on the TC intensity errors are most persistent at 4–5-day lead times in all three major ocean basins, indicating a significant control of global models on the forecast skill of the COAMPS-TC model. It is of interest to find, however, that lowering the 5-day track errors below 80 n mi (1 n mi = 1.852 km) does not reduce TC absolute intensity errors further. Instead, the 4–5-day intensity errors appear to be saturated at around 10–12 kt (1 kt ≈ 0.51 m s−1) for cases with small track errors, thus suggesting the existence of some inherent intensity errors in regional models. Additional idealized simulations under a perfect model scenario reveal that the COAMPS-TC model possesses an intrinsic intensity variation at the TC mature stage in the range of 4–5 kt, regardless of the large-scale environment. Such intrinsic intensity variability in the COAMPS-TC model highlights the importance of potential chaotic TC dynamics, rather than model deficiencies, in determining TC intensity errors at 4–5-day lead times. These results suggest a fundamental limit in the improvement of TC intensity forecasts by numerical models that one should consider in future model development and evaluation.

Laser-Material Interactions of High-Quality Ultrashort Pulsed Vector Vortex Beams.

Diffractive multi-beams based on 1 × 5 and 2 × 2 binary Dammann gratings applied to a spatial light modulator (SLM) combined with a nanostructured S-wave plate have been used to generate uniform multiple cylindrical vector beams with radial and azimuthal polarizations. The vector quality factor (concurrence) of the single vector vortex beam was found to be C = 0.95 ± 0.02, hence showing a high degree of vector purity. The multi-beams have been used to ablate polished metal samples (Ti-6Al-4V) with laser-induced periodic surface structures (LIPSS), which confirm the polarization states unambiguously. The measured ablation thresholds of the ring mode radial and azimuthal polarizations are close to those of a Gaussian mode when allowance is made for the expected absolute intensity distribution of a ring beam generated from a Gaussian. In addition, ring mode vortex beams with varying orbital angular momentum (OAM) exhibit the same ablation threshold on titanium alloy. Beam scanning with ring modes for surface LIPSS formation can increase micro-structuring throughput by optimizing fluence over a larger effective beam diameter. The comparison of each machined spot was analysed with a machine learning method—cosine similarity—which confirmed the degree of spatial uniformity achieved, reaching cosθ > 0.96 and 0.92 for the 1 × 5 and 2 × 2 arrays, respectively. Scanning electron microscopy (SEM), optical microscopy and white light surface profiling were used to characterize and quantify the effects of surface modification.

Blood Pressure Responses to Static and Dynamic Knee Extensor Exercise between Sexes: Role of Absolute Contraction Intensity.

Males have larger blood pressure (BP) responses to relative-intensity static handgrip exercise compared with females. Controlling for absolute load (maximal voluntary contraction (MVC)) abolishes these differences. Whether similar observations exist during large muscle mass exercise or dynamic contractions, and the mechanisms involved, remains unknown. BP, heart rate, muscle oxygenation (near-infrared spectroscopy), and rectus femoris EMG were recorded in 28 males and 17 females during 10% and 30% MVC static (120 s) and isokinetic dynamic (180 s; 1:2 work-to-rest ratio; angular velocity, 60°·s-1) knee extensor exercise. Static and dynamic exercises were completed on separate visits, in a randomized order. Sex differences were examined with and without statistical adjustment of MVC (ANCOVA). Males had larger systolic BP responses (interaction, P < 0.0001) and muscle deoxygenation (interaction, P < 0.01) than did females during 10% static exercise, with no difference in EMG (interaction, P = 0.67). Peak systolic BP was correlated with MVC (r = 0.55, P = 0. 0001), and adjustment for MVC abolished sex differences in systolic BP (interaction, P = 0.3). BP, heart rate, muscle oxygenation/deoxygenation, and EMG responses were similar between sexes during 30% static exercise (interaction; all, P > 0.2), including following adjustment for MVC (all, P > 0.1). Males had larger systolic BP responses during dynamic exercise at 10% and 30% (interaction; both, P = 0.01), which were abolished after adjustment for MVC (interaction; both, P > 0.08). Systolic BP responses were correlated with absolute MVC and stroke volume responses during 10% (r = 0.31, P = 0.04; r = 0.61, P < 0.0001, respectively) and 30% (r = 0.48, P = 0.001; r = 0.59, P < 0.0001, respectively). Absolute contraction intensity can influence systolic BP responses to 10% but not 30% MVC static, as well as 10% and 30% MVC dynamic knee extensor exercise, and should be considered in cross-sectional comparisons of exercise BP.

Numerical simulation of the interaction of wave phase conjugation with bubble clouds

The interaction of the Wave Phase Conjugation (WPC) process with bubble cloud dynamics is investigated via numerical modeling in application to bubble size measurements. The WPC simulator by Modarreszadeh and Timofeev (Computers and Fluids 197, 104353) is used as a starting point. In the simulator, a modified version of the high-order Nodal Discontinuous Galerkin method is used for modeling of acoustic wave propagation in the active WPC conjugator and the surrounding linear or non-linear fluid in 2D/axisymmetric domains. The effects of bubble dynamics are incorporated with the help of induced volume fractions. The modified Keller–Miksis model is employed to simulate vibrations of bubbles subjected to acoustic waves. After thorough verification and validation of the numerical scheme and the physical model, the interaction of various bubble clouds, including poly-disperse ones, with the WPC process is examined with the help of some existing and newly suggested descriptive indicators, e.g., the amplification factor and the absolute and relative signal intensities. The results show that signals scattered from bubble-plane clouds, in which the bubbles are non-physically synced, are strong enough to affect the modulation process if the stimulation frequency is close to the natural frequency of bubbles. For more realistic bubble clouds, the modulation process is almost intact. However, conjugate waves do carry some signatures of bubble-cloud dynamics, e.g., signals with frequencies higher than the natural frequency of bubbles are significantly diminished. The study demonstrates that WPC-based techniques have a promising potential to be used for measuring bubble dimensions.

New approach to precisely measure [formula omitted]-ray intensities for long-lived fission products, with results for the decay of 95Zr

For many fission products, the γ rays emitted following β decay provide an easily-detectable signature that can be used to identify their quantities and distributions in a sample. As a result, γ-ray spectroscopy is often exploited to study fission-product yields, provided sufficiently accurate information on the γ-ray intensity is available. However, in many cases, the uncertainties in the existing nuclear data are large enough that they compromise the precision achievable for modern experiments and applications. To address this need, we have developed a new experimental method that is well suited to precisely measure absolute γ-ray intensities in the β decay of long-lived fission products. The approach involves the production of a radiopure sample by implantation of a mass-separated ion beam from the CAlifornium Rare Isotope Breeder Upgrade (CARIBU) facility on a thin carbon foil. The emitted β-decay radiation is detected with a 4π gas proportional counter and a meticulously efficiency-calibrated high-purity germanium (HPGe) detector. As a first measurement to demonstrate the approach, we studied the absolute γ-ray intensities of the strongest transitions following the β decay of 95Zr and its decay-daughter 95Nb, and determined them to fractional precisions of better than 1–2%. In addition, with a larger sample of activity produced through neutron irradiation of an isotopically-enriched Zr foil, we performed a high-precision measurement of the relative γ-ray intensities following the decay of 95Zr with just the HPGe detector. The sample-production method at CARIBU and the coincidence detection approach demonstrated here can be applied to study fission products with half-lives longer than a day, which includes isotopes important not only for nuclear-energy and national-security applications, but also for medical-isotope research and environmental monitoring.

Intensity Paradox-Low-Fit People Are Physically Most Active in Terms of Their Fitness.

Depending on their cardiorespiratory fitness (CRF), people may perceive the exertion of incident physical activity (PA) differently. Therefore, the use of relative intensity thresholds based on individual fitness have been proposed to evaluate the accumulation of PA at different intensity levels. A subsample of the FinFit2017-study, 1952 adults (803 men and 1149 women) aged 20–69 years, participated in this study. Their maximal oxygen uptake (VO2max) was predicted with a 6 min walk test, and they were instructed to wear a triaxial hip-worn accelerometer for one week. The participants were divided into CRF tertiles by five age groups and sex. Raw acceleration data were analyzed with the mean amplitude deviation method in 6 s epochs. Additionally, the data were smoothed with 1 min and 6 min exponential moving averages. The absolute intensity threshold for moderate activity was 3.0 metabolic equivalent (MET) and for vigorous 6.0 MET. Correspondingly, the relative thresholds were 40% and 60% of the oxygen uptake reserve. Participants in the lowest CRF tertile were the most active with relative thresholds, and participants in the highest CRF tertile were the most active with absolute thresholds. High-fit people easily reached the absolute thresholds, while people in the lowest CRF tertile had to utilize most of their aerobic capacity on a daily basis simply to keep up with their daily chores or peers.

Research on characteristics of flow boiling and dryout inhibition of rifled tube

The two-fluid three-flow field mathematical model is used to carry out the numerical simulation of heat transfer characteristics of steam-liquid two-phase flow in dryout and post-dryout region of the rifled tube. The absolute vorticity flux and intensity of the secondary flow are introduced to quantitatively characterize the heat transfer enhancement. The results show that, compared with smooth tube, the rifled tube can greatly reduce the rise of wall temperature and have a significant effect on dryout inhibition. The cross-section wall temperature of rifled tube presents a periodic distribution. The wall temperature at the intersection of the root and rib side is higher due to the fluid retention. After the dryout occurs, the wall temperature is higher than other locations due to the continuous liquid film on the crest being torn. The secondary flow strength and heat transfer enhancement degree of fluid in rifled tube increase with the increase in axial height. The absolute vortex flux, intensity of the secondary flow and absolute value of the vorticity in main flow direction can reflect the degree of fluid disturbance caused by internal thread.

Effect of topical application of nanoencapsulated eugenol on dental sensitivity reduction after in‐office dental bleaching: a randomized, triple‐blind clinical trial

This randomized, split-mouth, triple-blind clinical study evaluated the effect of application of nanoencapsulated eugenol (NE) on the absolute risk and intensity of tooth sensitivity (TS) resulting from in-office bleaching. Fifty-six patients received a NE in one hemiarch and a placebo gel in the other hemiarch, determined by random sequence, before in-office bleaching. A visual analogue scale (VAS) (0-10) and a numeric rating scale (NRS) (0-4) were used to record TS during bleaching and 1 and 48 h after bleaching. The tooth color was performed from baseline to 2 weeks after bleaching with shade guides (ΔSGU) and a spectrophotometer (∆Eab , ∆E00, and WID ). The TS was assessed through the McNemar test (α = 0.05) and by the Wilcoxon signed-rank test (NRS) and paired t-test (VAS). The paired test-t was employed to compare the color changes (ΔSGU and ΔEab , ∆E00, and WID ). The significance level was 5%. No statistically significant difference was found in the absolute risk or intensity of TS between both groups (p > 0.05). A significant color change was observed in both groups (p > 0.05). Administration of the gel containing NE before the in-office dental bleaching did not reduce the TS and did not interfere in the bleaching effect. The use of desensitizing gel containing NE did not reduce in-office bleaching-induced tooth sensitivity.

Sonic Activation of a Desensitizing Gel Prior to In-Office Bleaching.

This double-blind, randomized, and controlled clinical trial evaluated the effect of sonic activation during the application of a desensitizing agent (DA) containing 5% potassium nitrate and 2% sodium fluoride on the occurrence of tooth sensitivity (TS) associated with in-office dental bleaching. Treatment with or without sonic activation of the DA was randomly assigned to one-half of the maxillary teeth of 34 patients in a split-mouth design. On the side without sonic activation (noSA), the DA was applied and maintained in contact with the teeth for 10 minutes. On the sonic activation side (SA), the DA was activated 30 seconds per tooth. The DA application was followed by application of 35% hydrogen peroxide in two bleaching sessions separated by a one-week interval. The primary outcome was the absolute risk of TS, recorded using a numeric rating scale and a visual analog scale. Color was evaluated with a digital spectrophotometer and a value-oriented shade guide. No significant difference between treatments was observed in the absolute risk of TS, which occurred in 93% (p=1.00) of both noSA and SA groups. The TS intensity was higher in the 24-hour interval after sessions, for both treatments, without differences between them. There was no difference in the color change for the treatments, with the average change in number of shade guide units of the Vita Classical scale of 6.35 for both (p=0.87). Sonic activation of DA containing 5% potassium nitrate and 2% sodium fluoride did not reduce the absolute risk and intensity of TS associated with in-office bleaching.

Comparison of the Effect of Agitation on Whitening and Tooth Sensitivity of In-Office Bleaching: A Randomized Clinical Trial.

This single-blind, split-mouth, randomized trial was aimed at evaluating the bleaching efficacy (BE) and tooth sensitivity (TS) of a 20% hydrogen peroxide (HP) bleaching agent used under active or passive application. Twenty-two patients with canines darker than C2 were selected. Teeth were bleached in two sessions, with a one-week interval between treatments. The bleaching agent was applied using active (HPactive) or passive (HPpassive) application. Each tooth in the HPactive-allocated hemiarch received bleaching gel with sonic activation after 10 and 30 minutes from the start of treatment, with rounded movements all over the buccal surface. The color changes were evaluated by subjective (Vita Classical and Vita Bleachedguide) and objective (VITA Easyshade Spectrophotometer) methods at baseline and 30 days after the second session. TS was recorded up to 48 hours after treatment using a 0-10 visual analog scale. Color change in shade guide units (SGUs) and ΔE was analyzed using a Wilcoxon test (α=0.05). The absolute risk and intensity of TS were evaluated using McNemar test and a Wilcoxon test, respectively (α=0.05). Significant whitening was observed in both groups after 30 days of clinical evaluation. The activation did not significantly influence BE (ΔSGU HPpassive=5.6 and HPActive=5.8; p=0.98; and ΔE HPpassive=10.6 and HPactive=10.3; p=0.83). Absolute risk of TS (HPactive=36.4% and HPpassive=31.8%; p=0.94) was similar for both groups (Fisher exact test). TS intensity (visual analogue scale) was higher during the bleaching sessions and up to 24 hours thereafter for both groups, with no differences between groups (two-way analysis of variance and Tukey). The active application of a 20% HP gel did not improve BE and TS.