CORRIGENDACorrigendumPublished Online:01 May 2007https://doi.org/10.1152/ajpheart.zh4-7517-corr.2007Original articleMoreSectionsPDF (119 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Volume 292, March 2007 Volume 61, March 2007 Adebiyi A, Zhao G, Cheranov SY, Ahmed A, Jaggar JH. Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries. Am J Physiol Heart Circ Physiol 292: H1584-H1592. First published November 10, 2006; doi:10.1152/ajpheart.00584.2006; http://ajpheart.physiology.org/cgi/content/full/292/3/H1584.On page H1588, the sentence in the third line of the left column should read as “Total KCa channel protein, when normalized to actin, was similar in cav-1+/+ and cav-1−/− arteries (Fig. 6, C and D; P > 0.05).” (Corrected text presented in boldface.)Figures 1 and 6 on pages H1586 and H1589, respectively, should appear as in the following (corrected text presented in boldface). Fig. 1.Myogenic constriction is attenuated in caveolin-1 (cav-1)−/− arteries. A: Western immunoblot illustrates the presence of cav-1 in cerebral arteries of control mice and the absence of cav-1 in cerebral arteries of cav-1−/− mice (data are representative of 4 experiments). In contrast, actin was detected in both cav-1+/+ and cav-1−/− arteries. B: representative traces illustrate that an elevation in intravascular pressure from 10 to 50 mmHg induces an attenuated myogenic constriction in a cav-1−/− artery, when compared with the response in a cav-1+/+ artery. C: relationship between intravascular pressure and myogenic tone in cav-1+/+ (n = 6) and cav-1−/− (n = 6) arteries. *P < 0.05 when compared with cav-1+/+ arteries at the same pressure. B and D: diltiazem (DTZ) significantly increased the diameter of both cav-1+/+ (n = 6) and cav-1−/− (n = 6) arteries. In the continued presence of DTZ, removal of extracellular Ca2+ did not cause any further increase in diameter. #P < 0.05 when compared with the respective control; †P < 0.05 when compared with cav-1+/+ at the same pressure. NS, nonsignificant difference.Download figureDownload PowerPoint Fig. 6.Iberiotoxin induces a similar depolarization and constriction in cav-1+/+ and cav-1−/− arteries, but total arterial KCa channel protein is similar. A: membrane depolarization induced by iberiotoxin (100 nM) is similar in pressurized (50 mmHg) cav-1+/+ (n = 6) and cav-1−/− (n = 6) arteries. B: iberiotoxin (100 nM) induces a similar constriction in cav-1+/+ (n = 6) and cav-1−/− (n = 6) arteries pressurized to 50 mmHg. C: representative Western immunoblots for KCa channel α-subunit and actin protein in cav-1+/+ and cav-1−/− cerebral artery lysates. D: mean data illustrating digital densitometric analysis of bands obtained by Western immunoblotting for KCa channel α-subunit normalized to actin (n = 4 separate experiments, with each experiment performed using arteries pooled from 4 mice, giving a total of 16 cav-1+/+ and 16 cav-1−/− mice used to obtain data).Download figureDownload PowerPointThis article has no references to display. Download PDF Previous Back to Top FiguresReferencesRelatedInformationRelated ArticlesCaveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries 01 Mar 2007American Journal of Physiology-Heart and Circulatory PhysiologyCited ByArterial remodeling and plasma volume expansion in caveolin-1-deficient miceSebastian Albinsson*, Yulia Shakirova*, Anna Rippe, Maria Baumgarten, Bert-Inge Rosengren, Catarina Rippe, Rupert Hallmann, Per Hellstrand, Bengt Rippe, and Karl Swärd1 September 2007 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 293, No. 3 More from this issue > Volume 292Issue 5May 2007Pages H2556-H2557 Copyright & PermissionsCopyright © 2007 by the American Physiological Societyhttps://doi.org/10.1152/ajpheart.zh4-7517-corr.2007History Published online 1 May 2007 Published in print 1 May 2007 Metrics