Abnormal Nutritional Status Research Articles

Nutritional status disorders in women with lichen sclerosus of the vulva

Research objective: to determine the characteristics of nutritional status (NS) in women of reproductive age with typical clinical signs of lichen sclerosus of the vulva (LSV) using key NS parameters. Materials and methods. The study included 75 women with average age 31.3 ± 1.3 years. 50 women were diagnosed with LSV and NS disorders (main group), and 25 women were practically healthy (control group). Information about all patients was collected through direct interviews, clinical examination and study of medical records. The presence of anogenital pruritus, soreness or burning, dryness, dyspareunia, urinary disturbances, perianal and/or intestinal symptoms, inflammatory bowel disease, thyroid dysfunction and tenderness, and other comorbidities were recorded. NS evaluated using anthropometric, laboratory and clinical studies. Body mass index, index of nutritional risk (nutritional deficiency), vitamins, micro- and macroelements value, scatological parameters were determined in all patients, and the intestinal microflora was examined.Results. The results of the study showed a disorder of NS in most patients with LSV by all studied parameters in comparison with the control group. Thus, it was found that 60% of patients with LSV had abnormal body mass index as well as NS was observed in 72% of patients. In addition, patients with LSV also had a higher deficiency of vitamins D and B12, and some important micro- and macronutrients. The results of the coprological study showed the neutral fats in feces, unchanged muscle fibers, extracellular and intracellular starch, decreased levels of bifidobacteria and lactobacilli in 68–74% of patients and opportunistic bacteria and fungi in 30–46% of women in the main group.Conclusions. Thus, the results of this study indicate the association between the abnormal NS and LSV. However, further research is needed to assess the course of the underlying disease and to analyze the metabolic pathways that lead to disorders of lipid, carbohydrate and protein metabolism in target patients, to select of the correct nutrients and alternative treatments.

Impact of the nutritional status of children with congenital heart diseases on the early post-operative outcome

BackgroundChildren with congenital heart disease (CHD) frequently become malnourished due to many factors including hypermetabolic state, inadequate caloric intake, malabsorption, and fluid restriction as part of the hemodynamic intervention. The abnormal nutritional status may affect early outcome after pediatric cardiac surgery; we aim to prove the importance of nutritional assessment and patient nutritional preparation before performing pediatric cardiac surgery.ResultsWe conducted a prospective observational cohort study from March 2013 till January 2015. All children from birth until 14 years of age admitted to the pediatric cardiac intensive care unit (PCICU) after cardiac surgery. Nutritional status was assessed preoperatively and prognostic nutritional index (PNI) was calculated. All post-operative outcome parameters, PCICU and hospital length of stay (LOS), ventilation time, the rate of infection, and ICU mortality were recorded. Two hundred fifty-nine children were evaluated. At admission, 179 patients (69%) had intake less than 50% of the recommended daily allowance (RDA) of calories intake. There was a statistically significant relationship between pre-admission RDA and the infection rate (P value 0.018). Severely malnourished patients had significantly longer ICU length of stay (LOS) (P value = 0.049). Similarly, weight and height percentiles have a significant effect on ICU LOS (P value 0.009 and 0.045) respectively. There was a significant relation between PNI ≥ 55 and the ICU LOS (P < 0.05), and ventilation time (P = 0.036). Delay in feeding postoperatively was associated with a higher risk of infection (P = 0.005), and higher mortality (P = 0.03).ConclusionsChildren with CHD were significantly malnourished preoperatively and had further weight loss postoperatively. Preoperative nutritional status and delayed postoperative enteral feeding were associated with a higher infection rate and mortality.

STATUS GIZI TERHADAP USIA MENARCHE REMAJA PUTRI

Background: Nutritional status is an important factor for assessing someone in good health or not suffering from diseases due to nutritional disorders. Abnormal nutritional status disrupts reproductive function. In this case, nutritional status is associated with the age of menarche. It is known that early age menarche has a risk of breast cancer.&#x0D; Objective: To determine the relationship between nutritional status and age of menarche.&#x0D; Method: Using a cross-sectional design. The sample size of 50 respondents, was selected using simple random sampling. Data collection includes assessing nutritional status, employment, and education of parents, both fathers and mothers, and physical activity using the PAQ-C questionnaire. Analysis of the data used in this study is the Chi-Square test and logistic regression test.&#x0D; Results: The results of the bivariate analysis showed a significant relationship between father's education and physical activity on the age of menarche with a p-value &lt;0.05 and the results of the multiple logistic regression test showed there was a relationship between overweight status and physical activity on the age of menarche with a p-value &lt; 0.05.&#x0D; Conclusion: Overweight nutritional status and mild physical activity show a significant relationship to the age of early menarche.

HUBUNGAN STATUS GIZI DENGAN PRODUKTIVITAS KERA PADA PEKERJA PEMETK TEH DI PT. SARANA MANDIRI MUKTI KABUPATEN KEPAHIANG TAHUN 2021

AbstractFrom a physiological point of view, productivity is a mental attitude that always tries and holds the view that the quality of life today is better than yesterday and tomorrow must be better than today. This attitude always encourages them not to feel satisfied with what they have achieved, but they always develop themselves and improve their work abilities. Meanwhile, work productivity is the ratio between the results achieved and the participation of a united time labor. A workforce with good nutrition will have a better work capacity and endurance, and vice versa, a workforce with poor nutrition and a heavy workload will interfere with work and accelerate fatigue.The purpose of this study was to determine the relationship between Nutritional Status and Work Productivity of Tea Picking Workers at PT. SaranaMandiriMukti, Kepahiang Regency. This type of analytic observational research with cross sectional design. Held on April 30 to May 6, 2021 at the PT. Sarana Mandiri Mukti Kepahiang Regency with a total population of 496 respondents. The tools used in this study were weighing scales to measure body weight, microtoas to measure height, and questionnaires and observations to measure work productivity.Based on the results of research on tea picker workers, there were 38 people with abnormal nutritional status, consisting of 28 people with a percentage of 45.9% fat, 10 people with a percentage of 16.3% thin, while 23 people with a normal nutritional status were 23 people with a percentage of 37.7. %. Those included in the productive category were 33 people (54.1%) and 28 people (45.9%) who were not productive. Based on the results of statistical tests using the Chi-square test, it was found that the relationship between nutritional status and work productivity was 0.031 (p &lt;0 , 05).Workers are expected to maintain and maintain normal nutritional status to support work productivity for workers

Factors Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, Vietnam

Background: In Vietnam, the horror and mortality of mother and child, whether legitimately or through the back door, is represented by traditions that predominate in the general public. Practices for supporting and educating infants fluctuate according to networks, depending on social tradition. The main objectives of this study were to investigate the situation when rearing and nurturing children and to explore the associated factors that affected to nutritional status of the children. Methods: A cross-sectional survey-based study conducted between September 2018 to April 2019 in ten obstetrics and gynecology clinics located in Ho Chi Minh City. Mothers were chosen if they have at least one child that at the age of 36 months or higher. Children body mass index (BMI) was calculated and assessed by using BMI-for-age-and-gender quantile. Logistic regression was performed where dependent variable was a discrete variable including normal and abnormal nutrition status. Results: The average age of the mothers was 29.4±4.6 years and the average age of the child was 24.1±5.7 months. Over half of the mothers maintain breastfeeding (50.6%). Child whose mothers lived in the rural area had 3.76 times higher risks to be under- or overweight, compared to those lived in rural regions (p=0.009). Child whose mother were well- educated was had a lower risk of abnormal nutritional status. Compared to those who earned high income, mothers earned low income had higher risks to have abnormal-nutritional-status children. Children who were breast-fed till 36 months old had the lower risks to be under- or overweight than the counterparts. Conclusion: The risks of children to be under- or overweight was positively affected by rural area, lower educated, low monthly income and was negative affected by the middle expenditure for child and breastfeeding till 36 months old. ow to Cite this Article Pubmed Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, SRP. 2020; 11(3): 341-344. doi:10.5530/srp.2020.3.41 Web Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, http://www.sysrevpharm.org/?mno=93061 [Access: March 30, 2021]. doi:10.5530/srp.2020.3.41 AMA (American Medical Association) Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, SRP. 2020; 11(3): 341-344. doi:10.5530/srp.2020.3.41 Vancouver/ICMJE Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, SRP. (2020), [cited March 30, 2021]; 11(3): 341-344. doi:10.5530/srp.2020.3.41 Harvard Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran (2020) Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, SRP, 11 (3), 341-344. doi:10.5530/srp.2020.3.41 Turabian Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. 2020. Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, Systematic Reviews in Pharmacy, 11 (3), 341-344. doi:10.5530/srp.2020.3.41 Chicago Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. Factors Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, Vietnam. Systematic Reviews in Pharmacy 11 (2020), 341-344. doi:10.5530/srp.2020.3.41 MLA (The Modern Language Association) Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran. Factors Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, Vietnam. Systematic Reviews in Pharmacy 11.3 (2020), 341-344. Print. doi:10.5530/srp.2020.3.41 APA (American Psychological Association) Style Thoai Dang Nguyen, Tram Thi Huyen Nguyen, Pol Van Nguyen, Thuy Phan Chung Tran (2020) Associated to Abnormal Nutritional Status of Children: A Survey from Clinics in Ho Chi Minh City, Systematic Reviews in Pharmacy, 11 (3), 341-344. doi:10.5530/srp.2020.3.41

Malnutrition and related factors in Filipino patients with Parkinson's disease: results from a pilot study.

Aim: Emerging evidence demonstrates a bidirectional relationship between nutritional status and Parkinson's disease (PD). Our aim was to determine the local prevalence of malnutrition and associated factors among Filipino PD patients. Materials & methods: We assessed the nutritional status of 95 PD patients using the body mass index (BMI) and Subjective Global Assessment (SGA) and identified malnutrition-associated factors. Results & conclusion: In our sample, the mean BMI was 24.5±4.2kg/m2. Consistent with published estimates, five (5.3%) patients were classified as underweightand 57 (60%) patients were classified asoverweight/obese. A total of 30 (31.6%)patients had abnormal nutritional status based on SGA. Weight-adjusted levodopa equivalent daily dose was a significant factor (p =0.032) for BMI, while dysphagia and higher weight-adjusted levodopa equivalent daily dose were found to be predictive of abnormal nutritional status using SGA (adjusted odds ratio of 8.85 [95% CI: 1.59-49.17; p =0.015] and 1.10 [95% CI: 1.02-1.20; p =0.021], respectively).

Nutritional Status and Health-Related Quality of Life in Men with Advanced Castrate-Resistant Prostate Cancer

Background Despite professional recommendations malnutrition is not adequately addressed in cancer patients. Here, we explored whether nutritional status (NS) is associated with HRQoL in men with metastatic castrate-resistant prostate cancer (mCRPC). Methods: Men with mCRPC enrolled into this prospective observational study were allocated to one of the four NS categories based on clinical, laboratory, and patient self-reported criteria: well-nourished (WN), nutritional risk without criteria for cachexia/sarcopenia (NR), sarcopenia, and cachexia. The HRQoL was evaluated by the Functional Assessment of Cancer Therapy-Prostate (FACT-P) questionnaire. Association between NS and self-reported HRQoL was sought by the linear regression model, which was adjusted for known prognostic variables and body mass index. Results: Over the period of two years, 141 patients were enrolled. Their median age was 74.1 years (IQR 68.6–79.4 years) and majority of them were minimally symptomatic. Fifty-nine patients (41.8%) were WN, followed by 24 (17%), 42 (29.8%), and 16 (11.4%) patients with NR, sarcopenia, and cachexia, respectively. As compared to WN patients, all three other NS categories were significant negative predictors of HRQoL (P < 0.04). Conclusions: Abnormal NS is highly prevalent in men with mCRPC and is negatively associated with their HRQoL, which supports the recommendation for management of malnutrition in these patients.

Malnutrition and Associated Motor and Non-motor Factors in People with Parkinson's Disease.

People with Parkinson's disease (PwP) are at higher risk of developing malnutrition. Several factors have been suggested to be involved including motor symptoms, non-motor symptoms, and treatment-related complications. The objective of the study was to analyze the combined effect of motor, non-motor, and pharmacological factors in the risk of malnutrition in PwP. Eighty-seven consecutive PwP were included in the study. Clinical data and pharmacological treatment were collected. Nutritional status was assessed using the Mini-Nutritional Assessment (MNA) questionnaire. Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Non-motor Symptoms Scale (NMSS), Hamilton Depression Rating Scale HAM-D, and Montreal Cognitive Assessment were applied. Thirty (34.4%) PwP were at risk of malnutrition and seven had malnutrition (8%). Abnormal nutritional status was associated with lower education, higher MDSUPDRS Parts I, II, and III and total scores, and higher scores in the NMSS domain of sleep disorders and fatigue. MDS-UPDRS motor score remained as a determinant of abnormal nutritional status, defined as MNA < 23.5, with an odds ratio 1.1 (95% confidence interval 1.01-1.10, p = 0.02). The main factor associated with nutritional status was severity of the motor symptoms as assessed by the MDS-UPDRS Part III. Non-motor symptoms and treatment-related complications were not associated with malnutrition.

Hubungan Antara Status Gizi Dengan Kejadian Anemia Pada Remaja Putri

A girl had a higher risk to get anemia because they consumed food that have a lower iron, usually girl wanted to look slim so that they limited to eaten food and girl had menstruation every month. If the habit of their eaten wrong will give rise to a problem like have a skinny body and indication of anemia. This research had a goal for find out the relation between nutritional status with indication of anemia on the girl. This research uses observational analityc methods with have approach on cross sectional of the seventy nine respondents. The process of taking the respondents was held by purposive sampling methods and data collection that use a scale, microtoise and digital hemometer. Research results of seventy nine respondents showed that most of them had an abnormal nutritional status which is they had a skin body 31(39,2%) and fat 11(14,0%). And almost half of all respondents got a indication of anemia. Data analysis results with chi square test (x²) showed that there was a relation between nutritional status with indication of anemia with p value= 0,000 (&lt;0,05), r hitung(34,700) &gt; r tabel(5,991). Girl who had a skin body tend havean indication of anemia and girl who had a normal nutritional status and who had a fat body tend haven't an indication of anemia.

Correlation between intensive phase treatment of antituberculosis drugs with nutritional status of patients with tuberculosis in Kupang city

Background: Indonesia is a country with the third highest tuberculosis incident in the world. Nutritional status is very important to patients with tuberculosis, an optimal nutritional status created an optimal immune system. Lack of adequate nutritional intake, prolonged the anti-tuberculosis drug treatment and caused them to get a slower recovery. Therefore, the writer found the need of knowing the relation of intensive phase treatment of anti-tuberculosis drugs with nutritional status of patients with tuberculosis in Kupang City.Objectives: To know the relation between intensive phase treatment of anti tuberculosis drugs with nutritional status of patients with tuberculosis in Kupang City.Methods: This study was an observational analytic study with a nested cohort design conducted by 11 public health centers in Kupang City by taking secondary data from medical records. The sampling technique used consecutive sampling with 84 respondents who met the inclusion and exclusion criteria. The study was analyzed univariately, and bivariately using Mc Nemar.Results: From 84 respondents, before intensive phase tuberculosis treatment 61 respondents (72.6%) had abnormal nutrition status, and 23 respondents (27.4%) had normal nutritional status, while after intensive phase tuberculosis treatment from 84 respondents it was found that 50 respondents (59.5%) had abnormal nutrition status, and 34 respondents (40.5%) had normal nutritional status. The result of the bivariate analysis test shows a significant different in nutritional status before and after tuberculosis treatment with p value = 0.001.Conclusions: There was a significant different in nutritional status before and after tuberculosis treatment indicating that anti-tuberculosis drug treatment can affect the nutritional status of patients with tuberculosis.Cl

Factors Associated with Work Fatigue in the Fuel Truck Drivers at Oil Company Padalarang

Fatigue can affect work productivity. Based on data obtained from Oil Company Padalarang in 2013 had 16 fuel truck accidents, work fatigue factor ranks 4th (25%). This study aims to determine the factors associated with work fatigue in fuel truck drivers Oil Company in 2015. The research design used was analytic survey study with Cross Sectional research design. With the number of cases 60 respondents, sampling techniques using Quota Sampling. Data collection using reaction timer, questionnaires and interviews. Data analysis using univariate and bivariate (Chi-Square) analysis. The results showed a description of work fatigue 61.7%, age at risk (?40 years) 65.0%, abnormal nutritional status 45.0%, work period (?5 years) 63.3% and heavy workload 38.3 %. It is known that there is a relationship between fatigue and age with P Value (0.002), work period with P Value (0.001), workload with P Value (0.018) and there is no relationship between work fatigue and nutritional status with P Value (0.936). It is recommended to provide a resting place for fuel truck drivers, making a policy to regulate the distance of fuel delivery between drivers who are old and young, do a health check before and after sending fuel and maintain a pattern of rest or sleep for fuel truck drivers.

Pemeriksaan Status Gizi Indeks Massa Tubuh Menurut Umur untuk Deteksi Dini Status Gizi Tidak Normal pada Remaja Puteri

AbstractMacro and micro nutrient deficiency in female adolescents causes the body to be thin and weight (BB) to drop dramatically impact on nutritional status becomes abnormal. One risk factor is an unbalanced diet. The nutritional status of adolescent girls can be seen from the results of the examination of Body Mass Index (BMI / U) by age. The importance of this nutritional status check is carried out considering that adolescent girls are one of the most potential human resources to assist development in a country because adolescents are the next generation and determiners of the future of this nation, in addition, adolescent girls are prospective mothers who will give birth to children of high quality to use for the development of a nation if it consumes food based on balanced nutrition. The examination of abnormal nutritional status of 68 teenage girls (39.3%) can trigger educational institutions in collaboration with health institutions and parents to immediately conduct nutritional interventions in the form of nutritional education, or cooking demonstrations of balanced nutrition requirements for teenagers and parents as a program to tackle problems of abnormal nutritional status and the risk of anemia for adolescent girls, so that nutritional problems in adolescents can be quickly resolved.

HUBUNGAN POLA MENSTRUASI DAN STATUS GIZI DENGAN KEJADIAN ANEMIA PADA REMAJA PUTRI DI SMA NEGERI 2 TEMBILAHAN

The high prevalence of anemia among teenagers if it is not be handled properly, it will continue into adulthood and contribute greatly to maternal and infant mortality. Preliminary study was conducted in Senior High School Number 2 Tembilahan were 10 respondents on the result of hemoglobin check, 4 respondents did not have anemia and 6 respondents experienced anemia. The purpose of this study was to determine the relationship of menstrual pattern and nutritional status with the incidence of adolescent anemia in Senior High School Number 2 Tembilahan. This type of research is analytic quantitative with cross sectional design. The sampling technique is simple random sampling . The population is class XI and XII students of Senior High School Tembilahan with the number 146 students and number of samples were 99 respondents. Data werw collected through a questionnaire and examination of hemoglobin levels and then processed using univariate and bivariate analysis with chi square test. The research result was obtained most of respondents aged 17 years old as many 48,5%, normal menstrual pattern is as many 63,6%, abnormal nutritional status is as many 50,5%, there are no anemia is as many 57,6%, there is relationship between menstrual pattern and between nutritional status with the incidence of anemia with value p value = 0,000. It is expected that the school will continue to collaborate with health workers of UPT Public Health Centre of Gajah Mada in giving KIE to all students.

Higher Proportion of Abnormal Nutritional Status Among Well-Suppressed HIV-Infected Elderly Asians Compared to HIV-Negative Individuals

Older adults face physiological, psychological, social, and economic changes, which may impair nutritional status, making the body vulnerable to illness and adverse clinical outcomes. Little is known regarding the nutritional status among elderly people living with HIV (PLHIV). We aimed to study the prevalence of malnutrition and the associated factors in a Thai aging cohort. A cross-sectional study was conducted among PLHIV >50 years of age on long-term antiretroviral therapy and HIV-negative controls, frequency matched by sex and age in Bangkok, Thailand. Nutritional status was assessed by the Mini Nutrition Assessment (MNA) tool. Abnormal nutritional status was defined as MNA score <24 (malnutrition and at risk of malnutrition). Body composition was measured by bioelectrical impedance analysis using Body Composition Analyzer. Demographic and disease-related factors were assessed for their association with abnormal nutrition status using multivariable logistic regression. There were 349 PLHIV and 103 HIV-uninfected controls, with median age 55 years. The majority were male (63%) with median body mass index (BMI) of 23.4 kg/m2. PLHIV had lower BMI [median, 23.1 (IQR, 20.8-25.2) vs. 25.3 (22.3-28.7) kg/m2, p < .001], lower fat percent [22.8% vs. 26.3%, p < .001] and lower fat mass [14.2 vs. 16.9 kg, p < .001] and higher abnormal nutritional status (18.05% vs. 6.8%, p = .005) than controls. In the multivariate model, older age (adjusted odds ratio [aOR], 1.06, 95% confident interval [CI]: 1.01-1.12, p = .03), positive HIV status (aOR, 2.67, 95% CI: 1.07-6.65, p = .036), diabetes mellitus (aOR, 2.21, 95% CI: 1.003-4.87, p = .049), lower fat mass (aOR, 0.70, 95%CI: 0.57-0.86, p < .001), and lower BMI (aOR, 0.63, 95% CI: 0.51-0.78, p < .001) were independently associated with abnormal nutritional status. PLHIV had higher risks for abnormal nutritional status compared with HIV-uninfected individuals. Regular screening and monitoring of nutritional status among PLHIV may promote better health outcomes.

Identification and prognostic impact of malnutrition in a population screened for liver transplantation

Sarcopenia is prevalent in patients with liver cirrhosis and is negatively associated with clinical outcomes. In a population screened for liver transplantation we aimed to assess the prevalence of abnormal nutritional status and to what extent a clinical screening tool is able to reliably select patients for extensive nutritional assessment including CT. We also evaluated which nutritional parameters are independently associated with clinical outcomes. Analysis of consecutive patients undergoing detailed nutritional assessment during pre-liver transplantation screening from October 2015 to April 2017. In 102 included patients (66.7% male; median age of 56.3 years (IQR 43.9-64.0); median MELDNa score of 14.7 (IQR 9.4-19.0)), presarcopenia was diagnosed in 30/102 patients (29.4%), sarcopenia in 20/102 (19.6%), and impaired muscle quality in 19/102 (18.6%). Application of the European association for the Study of the Liver rapid screen tool as the primary instrument for nutritional assessment would have resulted in selection of 40/69 cases, thus 42.0% of patients with actual muscle mass depletion and/or impaired muscle function would not have been selected for further nutritional evaluation. In contrast to muscle mass depletion, impaired muscle function was a significant predictor for 6-month decompensation-free (p=0.006) and hospitalization-free (p=0.003) survival, when adjusted for age and MELDNa score. In our population the efficacy of a clinical screening tool for malnutrition was unsatisfactory. A detailed nutritional assessment is therefore recommended in all patients undergoing liver transplantation screening. Impaired muscle function might be clinically more relevant than muscle mass depletion, and muscle function testing should be considered an integral part of nutritional assessment in chronic liver disease.

Interventions for Obesity and Nutritional Status in Arthroplasty Patients.

Nutritional risk in patients undergoing total joint arthroplasty has been well-studied with regard to diagnostic criteria; however, therapeutic management of abnormal body mass index (BMI) values and serum markers remains to be studied in patients undergoing joint replacement surgery. Patients with a BMI value of >40 kg/m2 are at increased risk for postoperative complications; weight loss programs and bariatric surgery are therapeutic modalities that can be used in the prehabilitation and long-term rehabilitation of patients undergoing total joint arthroplasty. Management of patients with abnormal nutritional status should be multidisciplinary and allow for the incorporation of dietitians and nutritionists in therapeutic planning. Hypoalbuminemia correction can be completed intravenously or orally; however, arthroplasty studies remain lacking with regard to the preferred modalities of correction.

The effectiveness of pancreatic enzyme replacement therapy using microencapsulated pancreatin preparations in the correction of nutritional status in patients with chronic pancreatitis: a prospective observational study

The goal is to evaluate the effectiveness of pancreatic enzyme replacement therapy (PERT) using microencapsulated pancreatin preparations for the correction of nutritional status in patients with chronic pancreatitis (CP) and associated exocrine pancreatic insufficiency (EPI). The study included 58 patients with CP who were divided into two groups depending on the results of a laboratory assessment of indicators of nutritional status: group I (n=30) consisted of patients with CP and signs of EPI (according to low elastase test values) without deviations in nutritional status; Group II (n=28) consisted of patients with CP with a EPI and an abnormal nutritional status. In both groups, patients during the entire observation period (8-12 months) received PERT using microencapsulated pancreatin preparations at a dose adjusted for the severity of permanent residence permit. Before and after the PERT course, the dynamics of anthropometric [body weight, body mass index (BMI)] and laboratory indicators of nutritional status (total protein, albumin, vitamins D and B12, transferrin, iron and magnesium) were evaluated. After the completion of PERT, a significant tendency towards an increase in BMI in patients was noted in both groups. In group I, this indicator increased from 21.45 [95% confidence interval (CI) 19.80-23.92] kg/m2 to 22.15 (95% CI 20.31-23.86) kg/m2, and in II group - from 19.22 (95% CI 18.33-21.99) kg/m2 to 22.0 (95% CI 19.97-24.08) kg/m2. At the same time, the duration of PERT (months) significantly correlated with the dynamics of the patient's body weight (r=0.4679; 95% CI 0.2384-0.6479, p=0.0002). When assessing laboratory markers of nutritional status after PERT, a general tendency was found to increase the levels of total protein, albumin, vitamin D, magnesium, transferrin, and iron in both groups, however, statistically significant differences in the dynamics were observed mainly in group II patients. So, the level of total protein in group II increased from 69.05 (95% CI 65.6717-70.9000) g/l to 72.8 (95% CI 71.1358-74.9000) g/l, vitamin D - from 10.6 (95% CI 32.8397-38.9603) ng/ml to 17.1 (95% CI 12.0166-23.6232) ng/ml, magnesium - from 0.72 ( 95% CI 0.6892-0.7825) mmol/L to 0.795 (95% CI 0.7692-0.8800) mmol/L, and transferrin from 2.91 (95% CI 2.1800-3.3656 ) g/l to 2.92 (95% CI 2.4000-3.5200) g/l. A prospective observational study demonstrated the effectiveness of PERT using microencapsulated pancreatin preparations in the correction of nutritional status in patients with CP.

Asthma prevalence and the impact of nutritional status on prescribed asthma medications in children

Introduction. Asthma and obesity are the most common chronic health disorders in children. Although heredity plays a significant role in their development, environmental factors and early exposure have contributed to the increasing incidence of both disorders in recent decades. The aim of the study was to estimate asthma prevalence in schoolchildren in Indjija, Srem District, Serbia, and to investigate differences in nutritional status of children with asthma as well as differences between their nutritional status and prescribed asthma medications. Material and Methods. A cross-sectional retrospective cohort study was conducted at the Primary Health Center in Indjija. Of all the medical records of children aged 6 - 14 years, a cohort of children with asthma was formed. The retrospective study evaluated their nutritional status and the prescribed asthma medications. Results. The prevalence of asthma in children aged 6 - 14 was 6.9%. Children with asthma were significantly more overweight and obese (40.5%) than children without asthma. Boys accounted for 63.7% of children with asthma, with a statistically significant gender difference. Abnormal nutritional status was found in 44.3% of children with asthma and boys with asthma were significantly more obese (23%) compared to girls (7.8%). Overweight and obese children with asthma were not prescribed significantly more medications to relieve asthma symptoms than normal-weight children. Conclusion. The prevalence of asthma among schoolchildren in Indjija was 6.9%. Children with asthma were more likely to be overweight and obese than children without asthma, whereas boys with asthma were significantly more obese than girls. No significant differences were found between their nutritional status and prescribed asthma medications.

Interaction of central obesity and sarcopenia on nutritional status in the community-dwelling older people

ObjectivesTo investigate the interrelationships between central obesity, sarcopenia and nutritional status in the elderly. MethodsWe enrolled 501 elderly (women: 47.5 %) with complete datasets. Biochemical and anthropometric data were measured after an overnight fast. Basic characteristics, psychosocial and behavioral factors, nutritional status, and history of chronic disease came from structured questionnaires. Central obesity was defined as waist circumference ≥ 90 cm for men, ≥ 80 cm for women. Sarcopenia was defined by the Asian consensus. Nutritional status was assessed using Mini Nutritional Assessment scores: abnormal nutritional status ≤ 23.5. Multiple logistic regression analysis was done to determine the independent factors of an abnormal nutritional status. ResultsNinety (18.0 %) participants had an abnormal nutritional status, 300 (59.9 %) had central obesity, 52 (10.4 %) sarcopenia and 3 (0.6 %) sarcopenic obesity. Central obesity (OR = 0.455, 95 % CI: 0.244-0.847) and total lymphocyte count (OR = 0.526, 95 % CI: 0.315-0.880) were negatively and sarcopenia (OR = 3.170, 95 % CI: 1.485–6.767), current smoking (OR = 4.071, 95 % CI: 1.357–12.211), and total number of chronic diseases (OR = 1.484, 95 % CI: 1.234–1.785) were positively associated with abnormal nutritional status. An analysis of the combine effects of central obesity and sarcopenia on nutritional status showed that significantly fewer participants with central obesity but not sarcopenia had abnormal nutrition than participants with sarcopenia with or without central obesity (12.8 % vs 38.5 or 65.4 %, p < 0.001). ConclusionsCentral obesity and sarcopenia were interactively associated with the nutritional status of older people living in a rural community.

P2607Quick nutritional assessment and prognosis in outpatients with heart failure with mid-range ejection fraction

Abstract Background Nutritional status is an important prognostic factor in patients with heart failure (HF) beyond body mass index, although its prognostic value in patients with mid-range left ventricular ejection fraction (HFmrEF) is not completely elucidated. In a pilot study we observed that the Mini Nutritional Assessment Short Form (MNA-SF) was the best approach for the screening of nutritional status in HF outpatients over others screening tools. Purpose To assess the prognostic role of malnutrition or risk of malnutrition in HFmrEF outpatients after the implementation of the MNA-SF screening tool in a routine way in a multidisciplinary HF. Methods The MNA-SF screening tool was administered during the global nurse evaluation of patients. The scoring ranges from 0 to 14, being 0 to7 as malnutrition status, 8 to 11 as at risk of malnutrition and 12 to 14 as normal nutritional status. For the present study those patients with malnutrition and at risk of malnutrition were merged and considered abnormal nutritional status. All-cause death was the primary end-point. Univariate and multivariate (backward conditional stepwise) Cox regression analyses were performed. Results Since October 2016 to November 2017, 153 HFmrEF patients were studied (mean age 68.8±11.7 years, 72.5% men, body mass index 28.4±4.4, LVEF 44% ± 3, NYHA class I 5.9%, II 86.3%, and III 7.8%). According to the MNA-SF 25 patients were (16.3%) fulfilled criteria of malnutrition (4) or where at risk of malnutrition (21). During a mean follow-up of 17.4±6.1 months, 23 patients died (15%). In the univariate analysis, nutritional abnormal status was significantly associated with all-cause death (HR 2.93 [1.23–7], p=0.02). In the multivariate analysis which included age, sex, NYHA functional class, body mass index, ischemic aetiology of HF and years of duration of HF, abnormal nutritional status remained significantly associated with all-cause mortality (HR 3.64 [1.39–9.54], p=0.009), together with NYHA functional class (HR 7.93 [2.69–23.4], p&lt;0.001) and years of HF duration (HR 1.10 [1.04–1.16], p=0.001). Conclusions Nutritional status assessed with the screening MNA-SF was an independent predictor of all-cause death in ambulatory patients with HFmrEF – beyond BMI – together with NYHA functional class and HF duration.