The following hindrances should be overcome to enhance the efficacy of photo-catalysts such as a poor-visible light response, high charge-carrier recombination rate, less surface area, and inappropriate band-edge alignment for photo-induced redox reaction. This study reported, visible light responsive Cu, Fe-co-doped Bi2Ti2O7/EG-g-C3N4 catalyst for photo-removal of organic pollutants. Series of characterization tools are used to testify and demonstrate the properties of formed material. The photo-removal efficiency of Cu, Fe-co-doped Bi2Ti2O7/EG-g-C3N4 hybrids are estimated to be 69.5 and 83.69% for ciprofloxacin and Rhodamine B organic molecules. Free radical trapping experiments were carried to predict active radical's participating in the reaction. The possible reaction mechanism was explained based on band edge potentials and trapping experiment results. This reporting Cu, Fe-co-doped Bi2Ti2O7/EG-g-C3N4 catalyst showed good durability. This work gives a new insight into coupling tactics of Cu, Fe-co-doped Bi2Ti2O7 and g-C3N4 material and which will helpful for designing efficient photocatalytic materials.