3D Plotting Research Articles

An Open-Source Deep Learning-Based GUI Toolbox For Automated Auditory Brainstem Response Analyses (ABRA).

In this paper, we introduce a new, open-source software developed in Python for analyzing Auditory Brainstem Response (ABR) waveforms. ABRs are a far-field recording of synchronous neural activity generated by the auditory fibers in the ear in response to sound, and used to study acoustic neural information traveling along the ascending auditory pathway. Common ABR data analysis practices are subject to human interpretation and are labor-intensive, requiring manual annotations and visual estimation of hearing thresholds. The proposed new Auditory Brainstem Response Analyzer (ABRA) software is designed to facilitate the analysis of ABRs by supporting batch data import/export, waveform visualization, and statistical analysis. Techniques implemented in this software include algorithmic peak finding, threshold estimation, latency estimation, time warping for curve alignment, and 3D plotting of ABR waveforms over stimulus frequencies and decibels. The excellent performance on a large dataset of ABR collected from three labs in the field of hearing research that use different experimental recording settings illustrates the efficacy, flexibility, and wide utility of ABRA.

3D Plotting of Gold Solubility and Gold Fineness: Quantitative Analysis of Ore-Forming Conditions in Hydrothermal Gold Deposits

Abstract The 3D plotting of gold solubility and gold fineness aims to illustrate how to quantify their correlations with ore-forming conditions in hydrothermal gold deposits. The thermodynamic calculation of the Au-Ag solid solutions in Mathematica and the 3D plotting in MATLAB are used to build isopleths of gold solubility and gold fineness at different temperatures (200℃, 400℃), pressures (0.1, 5 kbar), salinities (1, 40 wt% NaCl eq.), and sulfur concentrations (0.01, 0.5 mol/kg). The plot indicates that the ore-forming conditions have different correlations with gold solubility and gold fineness. Average rates of change for the correlations are quantified, showing distinct values in the four pH-logfO2 fields of (I) HSO4−, (II) SO42−, (III) H2S, and (IV) HS−, where dominant gold and silver complexes have different dependencies on the conditions. The quantification of the plots illustrates that a decrease in gold solubility by one order of magnitude is possibly caused by a decrease in temperature of ≥40℃, the salinity of ≥9.6 wt% NaCl eq. or sulfur concentration of ≥0.14 mol/kg, or an increase in pressure of ≥3 kbar, while a decrease in gold fineness by 100 units is possibly caused by a decrease in temperature of ≥14 ℃, pressure of ≥1.4 kbar, or salinity of ≥4 wt% NaCl eq., or an increase in sulfur concentration of ≥0.07 mol/kg. Quantification results suggest that a sharp decrease in temperature may result in large-scale gold mineralization and a great variation in gold fineness. In addition, the quantification reveals that the correlation between gold solubility and gold fineness can be expressed by a function, providing a rapid method for 3D plotting.

Impact of ICME- and SIR/CIR-Driven Geomagnetic Storms on the Ionosphere over Hungary

We investigate the differences between the effects of geomagnetic storms due to Interplanetary Coronal Mass Ejections (ICME) and due to Stream Interaction Regions or Corotating Interaction Regions (SIR/CIR) on the ionospheric F2-layer during the maximum of solar cycle 24. We have created a unique list of the ICME- and SIR/CIR-driven geomagnetic storm events for the time interval between November 2012 and October 2014. Finally, 42 clear ICME and 34 clear SIR/CIR events were selected for this analysis. The individual geomagnetic storm periods were grouped by seasons, time of day, and local time of Dstmin and were analyzed using three different methods: linear correlation analysis using 4-h averages of foF2 parameters and the geomagnetic indices (1st), daily variation of deltafoF2 (2nd), and 3D plotting: geomagnetic indices vs. time vs. deltafoF2 (3rd). The main phase day of the ICME- and SIR/CIR-induced geomagnetic storms was our main focus. We used manually evaluated ionospheric foF2 parameters measured at the Sopron ionosonde station and the geomagnetic indices (Kp, Dst, and AE) for this analysis. We have found that in most cases, the variation of the Dst index is the best indicator of the impact caused in the F2 layer. We conclude as well that the representation of the data by the third method gives a better description of the ICME and SIR/CIR-triggered storm behavior. In addition, our investigation shows that the SIR/CIR-related perturbations can be predicted with greater accuracy with the second method.

Composites consisting of calcium phosphate cements and mesoporous bioactive glasses as a 3D plottable drug delivery system.

Calcium phosphate cements (CPC) and mesoporous bioactive glasses (MBG) are two well studied biomaterial groups widely under investigation on their applicability to treat bone defects in orthopaedics and maxillofacial surgery. Recently the extrusion properties of CPC-MBG composites using a pasty CPC based on a hydrophobic carrier-liquid were studied in our group demonstrating that such composites are suitable for low temperature 3D plotting. Based on this work, we show in this study that by variation of the MBG content in the composite the degradation of the final scaffolds can be influenced. Furthermore, by modifying the cement phase and/or the MBG with therapeutically active ions like strontium, the released ion concentration can be varied over a wide range. In a second step the MBG was functionalized exploiting the high specific surface area of the glass as a carrier system for proteins like lysozyme or grow factors. We developed a protocol that allows the incorporation of protein-laden MBG in CPC pastes without impairing the extrudability of the CPC-MBG composites. Additionally, we found that released proteins from pure MBG or 3D plotted composite-scaffolds maintained their biological activity. Therefore, the combination of CPC and MBG allows the creation of a highly flexible composite system making it a promising candidate for bone tissue engineering. STATEMENT OF SIGNIFICANCE: Calcium phosphate cements and mesoporous bioactive glasses are two promising degradable biomaterials for the regenerative treatment of bone defects. The combination of both materials to a 3D printable composite enables the creation of implants with patient specific geometry. By varying the composition of the composite, the degradation behaviour can be influenced and especially the release of therapeutically active ions is tailorable over a wide range. We demonstrated this for strontium, as it has been shown to stimulate bone formation. Moreover, the bioactive glass can be used as a carrier system for drugs or growth factors and we show the successful combination of such functionalised glass particles and a cement paste without affecting the printability.

DFT insights into Nb-based 211 MAX phase carbides: Nb2AC (A = Ga, Ge, Tl, Zn, P, In, and Cd).

In this study, we performed the first-principles calculations to study the 211 MAX phase carbides: Nb2AC (A = Ga, Ge, Tl, Zn, P, In, Cd, and Al). The structural characteristics are in good agreement with those of the prior studies. The mechanical behavior has been explored by calculating the stiffness constants, elastic moduli, and Vickers hardness. The stiffness constants and phonon dispersion curves were used to check the structural stability of the selected compounds. 2D and 3D plotting of elastic moduli and calculated anisotropy indices disclosed the anisotropy of the elastic properties. We utilized the Mulliken atomic and bond overlap population to explain the mixture of ionic and covalent bonding among these carbides. The metallic behavior has been confirmed by calculating the band structure and density of states (DOS). Partial DOS was also used to discuss the bonding nature and strength among the different states. The optical properties of these phases have also been computed and analyzed to reveal possible relevance in diverse fields. The Debye temperature (Θ D), Grüneisen parameter (γ), melting temperature (T m), and minimum thermal conductivity (K min) were studied to bring out their possible relevance in high-temperature technology. The outcomes of this research indicate that the titled carbides are suitable for use as solar radiation-protecting coating and thermal barrier coating (TBC) materials.

Edge-based 3D vibration measurement of rotating cylinder-shaped structure through epipolar line-based corresponding point extraction between two camera images

Three-dimensional (3D) vibration measurements are important for monitoring rotating structures in order to reproduce the directional displacements of vibration signals such that they are similar to the actual movement. Photogrammetric techniques, which can be used to determine the relationship between 3D objects and their two-dimensional images, allow 3D vibrations in a structure to be measured without direct contact. Therefore, we herein present a multipoint 3D vibration measurement approach for rotating cylinder-shaped structures, which performs the imaging of a structure from two directions using two cameras. First, an epipolar line-based corresponding point extraction technique is applied to extract the corresponding regions of interest (ROIs) in videos acquired by the two cameras placed at 90° to the structure. Subsequently, an edge-based vibration measurement approach is used to detect vibrations in the corresponding ROIs. Noise reduction is then applied to reduce the noise, induced by the cameras or edge-based vibration measurement technique, by extracting and employing the frequencies at which the vibrations were occurring to the phase-based motion magnification technique. Subsequently, vibrations in the corresponding ROIs of the magnified videos are detected. For 3D plotting, the two vibration signals are combined. Simulation and real datasets are prepared for the qualitative and quantitative assessments of the proposed method. The simulation data results are compared with the results obtained before noise reduction, those obtained after noise reduction via bandpass filtering, and the reference data. A 3D vibration analysis is performed on the real data in multiple ROIs. The results yielded by the proposed method can be used to identify the weak points in a rotating cylinder-shaped structure that cause the structure to function abnormally.

UV curing-assisted 3D plotting of ceramic feedstock containing thermo-regulated phase-separable, photocurable vehicle for dual-scale porosity structure

We propose a novel approach for manufacturing dual-scale porosity alumina structures by UV curing-assisted 3D plotting of a specially formulated alumina feedstock using a thermo-regulated phase separable, photocurable camphene/triethylene glycol dimethacrylate (TEGDMA) vehicle. In particular, 3D plotting process was conducted at - 5 °C, and thus an alumina suspension prepared using liquid camphene/TEGDMA at room temperature could undergo phase separation, resulting in camphene crystals surrounded by walls comprised of liquid photopolymer enclosing alumina particles. To enhance the shape retention ability of extruded filaments, polystyrene (PS) polymer was used as the tackifier . The phase-separated feedrod could be extruded favorably through a nozzle and rapidly photopolymerized by UV light during the 3D plotting process. Thr ee-dimensionally interconnected macropores were tightly constructed, which were separated by microporous alumina filaments, where micropores were created by the removal of camphene crystals via freeze-dying. The macroporosity of porous alumina ceramics was controlled by adjusting the distance between deposited filaments, while their microporosity was kept constant, leading to tightly tailored overall porosity and mechanical properties.

3D Plotting of Calcium Phosphate Cement and Melt Electrowriting of Polycaprolactone Microfibers in One Scaffold: A Hybrid Additive Manufacturing Process.

The fabrication of patient-specific scaffolds for bone substitutes is possible through extrusion-based 3D printing of calcium phosphate cements (CPC) which allows the generation of structures with a high degree of customization and interconnected porosity. Given the brittleness of this clinically approved material, the stability of open-porous scaffolds cannot always be secured. Herein, a multi-technological approach allowed the simultaneous combination of CPC printing with melt electrowriting (MEW) of polycaprolactone (PCL) microfibers in an alternating, tunable design in one automated fabrication process. The hybrid CPC+PCL scaffolds with varying CPC strand distance (800–2000 µm) and integrated PCL fibers featured a strong CPC to PCL interface. While no adverse effect on mechanical stiffness was detected by the PCL-supported scaffold design; the microfiber integration led to an improved integrity. The pore distance between CPC strands was gradually increased to identify at which critical CPC porosity the microfibers would have a significant impact on pore bridging behavior and growth of seeded cells. At a CPC strand distance of 1600 µm, after 2 weeks of cultivation, the incorporation of PCL fibers led to pore coverage by a human mesenchymal stem cell line and an elevated proliferation level of murine pre-osteoblasts. The integrated fabrication approach allows versatile design adjustments on different levels.

New dynamical soliton propagation of fractional type couple modified equal-width and Boussinesq equations

The space–time fractional coupled modified equal-width equation and the coupled Boussinesq equation are a category of fractional partial differential equations, which might be crucial mathematical feathers in nonlinear optics, solid-state physics, vibrations in the nonlinear string, ion sound waves in plasma, hydro-magnetic waves in cold plasma and many more. To assemble such new exact solutions of the mentioned equations, the Sine-Gordon expansion (SGE) technique has been proposed with inside the sense of conformable derivative and the fractional order partial differential equation that is capable to change into an ordinary differential equation by using the traveling wave transform. In this article, the SGE technique has been employed to search the higher-dimensional fractional nonlinear evolution equations and hooked up consistent soliton solutions to the faster thought fractional nonlinear evolution equations through installing use of the prolonged higher-dimensional SGE technique. The compatibility of the extended SGE technique confirms through the scoring of soliton solutions. Moreover, we explored a couple of varieties of solutions over the maple calculations, including soliton, kink types, bell types, single soliton type, dark soliton, singular kink type, and anti-bell type solutions for distinct values of constants, which have been illustrated by the usage of 3D, list-point, contour analysis, and vector plotting. It is far incredible to understand that the feature of the solutions relies upon the selection of the parameters from the figures. This takes a look at an impactful position in studying higher-dimensional fractional nonlinear evolution equations through the prolonged SGE technique.

Surface Coverage Simulation and 3D Plotting of Main Process Parameters for Molybdenum and Vanadium Adsorption onto Ferrihydrite.

Ferrihydrite, FHY, was synthesized and characterized for morphology, mineralogy, surface area, hydrodynamic diameter and surface charge properties before molybdenum (Mo) and vanadium (V) adsorption. The potentiometric titration results showed first direct evidence that CO2 affects FHY surface sites at pH 6–9. Beside CO2, particles concentration may affect surface properties with an impact on adsorption performance. Additional new adsorption simulation results on theoretical surface coverage vs. experimental results obtained at varying particles concentration help theoreticians and experimentalists to better estimate and apply anion adsorption processes to real environments and suggest that simulation may not always be entirely reliable. Uptake capacities obtained experimentally, varying pH, particles and metals concentrations, were plotted to assess their synergetic effect and derive trends for future process optimization. Adsorption kinetics and isotherms were also considered. Experimentally derived values for maximum uptake capacities (0.43 and 1.20 mmol g−1, for Mo and V, respectively) and partitioning coefficients have applications, such as in making decisions for anions removal from wastewaters to achieve depollution efficiency or concentration required for effluents discharge and also implications in elements cycling from a geochemical perspective. In this work, the 3D plotting of the main adsorption process parameters obtained experimentally showed inter-correlations between significant process parameters that influence the adsorption process, and provides guidelines for its optimization and indicates that laboratory data can be transposed to real systems.

UV curing–assisted 3D plotting of core-shelled feedrod for macroporous hydroxyapatite scaffolds comprised of microporous hollow filaments

The present study demonstrates the manufacturing of macroporous hydroxyapatite (HA) scaffolds, comprised of microporous hollow filaments with high shape retention, by UV curing-assisted 3D plotting using a feedrod comprised of a photocurable HA shell and a carbon black (CB) core. Two types of scaffolds with different filament interspaces (0.5 mm and 1 mm) were produced by depositing core-shelled filaments extruded through a 1.07-mm-diameter nozzle with in situ polymerization process. Both scaffolds exhibited that the hollow HA filaments were produced after the removal of CB core by heat-treatment, while micropores in the HA walls were created as the replica of camphene-camphor crystals. Overall porosity and macroporosity obtained using a camphene-camphor content of 60 vol% increased from 74.3 vol% to 79.3 vol% and from 50.7 vol% and 64.6 vol%, respectively, with an increase in filament interspace sizes from 0.5 mm to 1 mm. Both scaffolds exhibited reasonably high compressive strengths (2.36 ― 3.58 MPa) and modulus (68–86 MPa).

3D Plotting of Silica/Collagen Xerogel Granules in an Alginate Matrix for Tissue-Engineered Bone Implants.

Today, materials designed for bone regeneration are requested to be degradable and resorbable, bioactive, porous, and osteoconductive, as well as to be an active player in the bone-remodeling process. Multiphasic silica/collagen Xerogels were shown, earlier, to meet these requirements. The aim of the present study was to use these excellent material properties of silica/collagen Xerogels and to process them by additive manufacturing, in this case 3D plotting, to generate implants matching patient specific shapes of fractures or lesions. The concept is to have Xerogel granules as active major components embedded, to a large proportion, in a matrix that binds the granules in the scaffold. By using viscoelastic alginate as matrix, pastes of Xerogel granules were processed via 3D plotting. Moreover, alginate concentration was shown to be the key to a high content of irregularly shaped Xerogel granules embedded in a minimum of matrix phase. Both the alginate matrix and Xerogel granules were also shown to influence viscoelastic behavior of the paste, as well as the dimensionally stability of the scaffolds. In conclusion, 3D plotting of Xerogel granules was successfully established by using viscoelastic properties of alginate as matrix phase.

Tumor Detection and Sectional Analysis in 3D Model

Tumor detection is a necessary task that identifies the presence of the tumor with the help of image processing. In this paper, image processing is used for the detection of the tumor with enough precision for doctors to understand about shape and size of a tumor. The 3D mapping task of a tumor is followed by image processing of each MRI (Magnetic Resonance Imaging) slice. This 3D plotting is performed with the Plotly Python library. This approach is helpful for doctors to understand the tumor at each slice. With color differentiation, every MRI slice is visualized in the X, Y, and Z-axis. A tumor specialist can identify the size of a tumor with every co-ordinate plotted. This paper gives the solution for almost every tumor and its organ visualization. The slight change in parameters of the image processing algorithm can detect a tumor in multi organs.

Toward Biofabrication of Resorbable Implants Consisting of a Calcium Phosphate Cement and Fibrin-A Characterization In Vitro and In Vivo.

Cleft alveolar bone defects can be treated potentially with tissue engineered bone grafts. Herein, we developed novel biphasic bone constructs consisting of two clinically certified materials, a calcium phosphate cement (CPC) and a fibrin gel that were biofabricated using 3D plotting. The fibrin gel was loaded with mesenchymal stromal cells (MSC) derived from bone marrow. Firstly, the degradation of fibrin as well as the behavior of cells in the biphasic system were evaluated in vitro. Fibrin degraded quickly in presence of MSC. Our results showed that the plotted CPC structure acted slightly stabilizing for the fibrin gel. However, with passing time and fibrin degradation, MSC migrated to the CPC surface. Thus, the fibrin gel could be identified as cell delivery system. A pilot study in vivo was conducted in artificial craniofacial defects in Lewis rats. Ongoing bone formation could be evidenced over 12 weeks but the biphasic constructs were not completely osseous integrated. Nevertheless, our results show that the combination of 3D plotted CPC constructs and fibrin as suitable cell delivery system enables the fabrication of novel regenerative implants for the treatment of alveolar bone defects.

Geometry and classification of carved Monge surfaces

There are more and more needs of new forms in the world architecture. The thin shells theory and the surfaces theory give enough materials to scientifics and designers. This article is devoted to the geometric investigation of carved Monge surfaces. The geometry of these surfaces is inner and outer. For this, the coefficients of their fundamental forms are found and allow the classification of these surfaces. The kinetic method is used for their geometric investigation and classification. The parametric definitions of these multitude forms of carved Monge surfaces allow the 3D plotting of these surfaces by mean of the software MathCAD. The results obtained by this investigation are their vector, implicite, explicite and parametric definitions, the mathematic modelling of their inner and outer geometry, their 3D plotting and their classification. This variety of carved Monge surfaces can be used as the median surface of thin elastic shells design from them. The geometry these elastic shells, because their thin is the one of the carved Monge surfaces. The multitude of the designed thin elastic shells are expressive, durable and cover large spans. The multitude of their forms can find applications in the architecture of civil and industrial buildings and also in mechanical engineering.

CREATION OF HIGH DEFINITION MAP FOR AUTONOMOUS DRIVING

Abstract. High Definition Map (HD Map) is one of the essential components for autonomous driving systems. The HD Map helps localization, detection, prediction and planning of autonomous driving cars in combination with GNSS and IMU sensors. A lot of map providers and major car manufactures have been trying the development of efficient ways to create and update HD Maps with centimeter-level precision. However, there are no open standard ways well-established to produce HD Map at the present time. Since 2013, we have been being engaged in the research projects and actual production projects on the creation of HD Maps. This paper introduces practical knowledge on five key steps of our large-scale production lines for HD Map creation, which are 1) Mobile Mapping System (MMS) survey, 2) 3D plotting, 3) Feature attributes editing and road network topology building, 4) Format conversion and 5) Quality assurance.

Additive Manufacturing in the Geopolymer Construction Technology: A Review

This research paper presents a scientific attempt of a comprehensive systematic review of three-dimensional printing in geopolymer construction technology. The concept of 3D printing is an automated manufacturing process, layer- by- layer command, with computer-aided design model to create physical objects, acquiring swift development for the last few decades. An expansion of novel Geopolymer technology has been adopted in the construction and infrastructure industries for decades. The critical challenges of construction and infrastructure industries, such as the need for architectural, holistic, and rational designs, can be dealt with 3D printing techniques. Plentiful advantages of this emerging novel technology include a reduced amount of cost, ease of construction, a lesser amount of time, freedom of design, less wastage, aptitude to create complex structures, decrease in labor requirements, etc. Accordingly, The paper discusses common 3D techniques, such as Fused Deposition Modelling, Selective Laser Sintering, Stereolithography, 3D plotting, Laminated Object Manufacturing technique, Direct Energy deposition technique or laser engineered net shaping, Powder Bed Fusion and Inject Head 3D printing and direct deposition method. Overall, this study provides an introduction of 3D printing automation and robotics processes in a geopolymer construction industry. Ultimately, the paper emphasizes to motivate researchers towards future studies about 3D printing.

3D Bioprinting of osteochondral tissue substitutes \u2013 in vitro-chondrogenesis in multi-layered mineralized constructs

For the generation of multi-layered full thickness osteochondral tissue substitutes with an individual geometry based on clinical imaging data, combined extrusion-based 3D printing (3D plotting) of a bioink laden with primary chondrocytes and a mineralized biomaterial phase was introduced. A pasty calcium phosphate cement (CPC) and a bioink based on alginate-methylcellulose (algMC) – both are biocompatible and allow 3D plotting with high shape fidelity – were applied in monophasic and combinatory design to recreate osteochondral tissue layers. The capability of cells reacting to chondrogenic biochemical stimuli inside the algMC-based 3D hydrogel matrix was assessed. Towards combined osteochondral constructs, the chondrogenic fate in the presence of CPC in co-fabricated and biphasic mineralized pattern was evaluated. Majority of expanded and algMC-encapsulated cells survived the plotting process and the cultivation period, and were able to undergo redifferentiation in the provided environment to produce their respective extracellular matrix (ECM) components (i.e. sulphated glycosaminoglycans, collagen type II), examined after 3 weeks. The presence of a mineralized zone as located in the physiological calcified cartilage region suspected to interfere with chondrogenesis, was found to support chondrogenic ECM production by altering the ionic concentrations of calcium and phosphorus in in vitro culture conditions.

3D Printing of Bone Grafts for Cleft Alveolar Osteoplasty - In vivo Evaluation in a Preclinical Model.

One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. Current clinical practice, the augmentation of the persisting alveolar bone defect by using autologous bone grafts, has considerable disadvantages motivating to an intensive search for alternatives. We developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials and integration of osteogenic cells allowing fabrication of patient-specific, tissue-engineered bone grafts. Objective of the present study was the in vivo evaluation of implants in a rat alveolar cleft model. Scaffolds were designed according to the defect’s geometry with two different pore designs (60° and 30° rotated layer orientation) and produced by extrusion-based 3D plotting of a pasty calcium phosphate cement. The scaffolds filled into the artificial bone defect in the palate of adult Lewis rats, showing a good support. Half of the scaffolds were colonized with rat mesenchymal stromal cells (rMSC) prior to implantation. After 6 and 12 weeks, remaining defect width and bone formation were quantified histologically and by microCT. The results revealed excellent osteoconductive properties of the scaffolds, a significant influence of the pore geometry (60° > 30°), but no enhanced defect healing by pre-colonization with rMSC.

Novel poly(ε-caprolactone) scaffolds comprised of tailored core/shell-structured filaments using 3D plotting technique

This study presents a novel type of poly(ε-caprolactone) (PCL) scaffold comprised of tailored core/shell-structured filaments. The scaffold can be produced using a nonsolvent-induced phase separation phenomenon during the 3D plotting of PCL solutions in a coagulation bath. Specifically, a mixture of water and ethanol was employed as the nonsolvent, in order to tailor the phase separation behavior of a PCL/acetone solution. The addition of water to ethanol allowed for the creation of dense shells due to the fast exchange between acetone and water during the early stage of the 3D plotting process, while in the cores a number of micropores were formed. In addition, the thickness of the dense shell increased with an increase in water content in the water/ethanol mixture, increasing the mechanical properties (i.e., tensile strength, modulus, and strain at failure) of the porous PCL scaffolds with tailored core/shell-structured filaments remarkably.