Advanced digital volume correlation (DVC) combined with X-ray computed tomography (XCT) was utilized to investigate the 3D crack propagation in nodular graphite cast iron under tensile loading. The objective of this work was to quantify crack growth at the voxel-scale and extract fracture mechanics parameters such as the 3D crack front, crack opening displacements (CODs), and stress intensity factors (SIFs). By employing a crack growth updating strategy and an adaptive multiscale mesh, the 3D crack shape and propagation were accurately captured throughout the entire process. Von Mises strain and COD fields were characterized to provide insights into plastic zones and variations in crack opening behavior. Estimation of SIFs revealed a mode I dominant regime and limited influence from modes II and III. This study provides comprehensive insights into crack propagation and crack opening behavior, providing valuable information to fracture mechanics.