The experiment was conducted to determine the effects of vacuum and non-vacuum packaging on the total phenolic content of encapsulated O. stamineus spray-dried powder when stored under different temperatures (10 and 25 °C) for 4 weeks of storage period. The total phenolic compound was measured using the Folin-Ciocalteu method and was analyzed using UV/VIS spectrophotometer. The results showed that both vacuum and non-vacuum packing affected the consistency of capsulated O. stamineus spray-dried powder during storage. The total phenolic content of the samples significantly increased for both vacuum and non-vacuum packaging when stored at 10 °C. However, the total phenolic content of the samples for both vacuum and non-vacuum packaging decreased after 2 weeks of the storage period when the samples stored at room temperature, 25 °C. Thus, it is suggested to keep the encapsulated O. stamineus spray-dried powder under low temperature (10 ˚) with vacuum packaging to sustain the medicinal properties quality and to prolong the shelf-life of the encapsulated products.