2nd Edition Research Articles

Cops, Teachers and Counselors, 2nd edition: narratives on the front line of public services

Cops, Teachers and Counselors, 2nd edition: narratives on the front line of public services

Buddhism as Philosophy, 2nd edition, by Mark Siderits

Buddhism as Philosophy, 2nd edition, by Mark Siderits

Theory and Reality: An Introduction to the Philosophy of Science, 2nd edition, by Peter Godfrey-Smith

Theory and Reality: An Introduction to the Philosophy of Science, 2nd edition, by Peter Godfrey-Smith

Isotianil (2nd edition) (Pesticides).

Food Safety Commission of Japan (FSCJ) conducted a risk assessment of isotianil (CAS No. 224049-04-1), an isothiazole agent for induced resistance to blast disease. This evaluation was requested from Ministry of Agriculture, Forestry and Fisheries (MAFF) on the reevaluation article of Agricultural Chemicals Regulation Act. Additional information including the fate in livestock (goats and chickens) and genotoxicity, and also the list of published scientific literature were newly submitted from the MAFF. The following data were used in the assessment; fate in plants (including paddy rice and potatoes), residues in crops, fate in livestock (goats and chickens), residues in livestock products, fate in animals (rats), subacute toxicity (rats, mice and dogs), chronic toxicity (rats and dogs), carcinogenicity (rats and mice), two-generation reproductive toxicity (rats), developmental toxicity (rats and rabbits), and genotoxicity. Major adverse effects of isotianil were observed in the stomach (mucosal epithelium hyperplasia of the forestomach limiting ridge in rats), the liver (including organ weight gain), and the kidney (including chronic nephropathy). No adverse effects were observed on carcinogenicity, fertility, teratogenicity, and genotoxicity. The lowest no-observed-adverse-effect level (NOAEL) obtained from the studies described above was 2.83 mg/kg bw per day in a one-year chronic toxicity study in rats. FSCJ specified an acceptable daily intake (ADI) of 0.028 mg/kg bw per day based on the NOAEL after applying a safety factor of 100. An acute reference dose (ARfD) was judged unnecessary to be specified, based on the results of a single oral administration of isotianil and other related tests.

Philosophy of Sport: Core Readings, 2nd edition, edited by Jason Holt

Philosophy of Sport: Core Readings, 2nd edition, edited by Jason Holt

Review of the book: Byzantinorossica. Code of Byzantine literary about Russia (until 13th century). T. IV / Author-compilator M. V. Bibikov. The 2nd edition. Moscow: Dom YaSK, 2021. 478 p

Review of the book: Byzantinorossica. Code of Byzantine literary about Russia (until 13th century). T. IV / Author-compilator M. V. Bibikov. The 2nd edition. Moscow: Dom YaSK, 2021. 478 p

Sumner’s Hemodynamic Guide to Venous Diagnosis and Intervention

The 2nd Edition of ‘Strandness & Sumner’s hemodynamics for Surgeons’ for the venous section. Editors: Seshadri Raju, Jose Almeida, Ghassan Kassab, and Fedor Lurie.

Infant gross motor development and childhood physical activity: Role of adiposity

Later achievement of standing and walking in infancy predicts childhood physical inactivity. This study aimed to examine associations between ages of achieving six gross motor milestones and childhood physical activity, and whether these associations were mediated by adiposity. A retrospective analysis of a subset from a cohort study. Data were available for 211 first-grade primary school children (aged 6–7 years) in the Kanto region, Japan. Information on ages of achieving holding head up, sitting, crawling, standing supported, walking supported, and independent walking were obtained from parental records in the Maternal and Child Health Handbooks. Adiposity was assessed using dual-energy X-ray absorptiometry, and expressed as body fat percentage. Current gross motor skills were assessed by the Test of Gross Motor Development 2nd edition. Physical activity was measured using a triaxial accelerometer and defined as time involved in moderate-to-vigorous-intensity physical activity (MVPA). Multiple regression analyses revealed that the age of achieving standing supported was negatively associated with MVPA (p ​= ​.021), while ages of achieving crawling (p ​= ​.010), standing supported (p ​= ​.002), and walking supported (p ​= ​.033) were positively associated with adiposity, after adjusting for potential confounders including current gross motor skills. When adiposity was introduced as a covariate, the age of achieving standing supported was still associated with MVPA (p ​= ​.048), and the indirect effect of achievement of standing supported on MVPA was not significant. Infants who achieve standing supported at a later age are less likely to be active during early school age, and adiposity may not mediate this association.

Self-concept among Indonesian adolescents in coastal areas: A cross-sectional study.

Adolescence is a transitional phase from childhood to adulthood, characterized by various biological, psychological, and social changes. Adolescents living in coastal regions are exposed to social-environmental risk factors that can affect their emotional wellbeing, primarily due to the demanding and unpredictable nature of coastal communities. These challenging and volatile circumstances can have a negative impact on adolescents' emotions, making them more vulnerable to mental and emotional disorders. This study aimed to examine the self-concept and its differences according to sociodemographic factors among adolescents residing in coastal areas of Indonesia. A cross-sectional design was employed for this study, which involved 644 adolescents living in coastal regions of Indonesia, specifically in the West Sumatra and Bali provinces. The Tennessee Self Concept Scale (TSCS) 2nd Edition Short Form was used to assess self-concept from August to September 2022. Descriptive statistics, Independent-t-test, and One-way ANOVA were utilized for data analysis. The findings revealed that adolescents in coastal areas had a high level of self-concept. A statistically significant difference was discovered in the overall self-concept according to gender (p = 0.002). Similarly, a significant difference was observed in the physical domain based on class level (p = 0.019). Regarding the personal domain, significant differences were identified according to age (p = 0.030), class level (p = 0.030), parent's marital status (p = 0.030), father's education (p = 0.05), and family income (p = 0.01). Furthermore, in the family domain, significant differences were found based on parents' marital status (p <0.001) and adolescents' residence status (p = 0.002). Additionally, a significant difference in the academic domain was observed with respect to gender (p = 0.001). However, no significant differences were noted in the moral ethics and social domains across all sociodemographic variables (p >0.05). This study emphasizes the need for attention from various stakeholders, including mental health nurses, to prioritize interventions to promote positive self-concept among adolescents, consider sociodemographic factors that influence self-concept, and address areas of dissatisfaction such as moral behavior and academic/work efficiency. Incorporating family support and nurturing positive parent-child relationships are also important for fostering a healthy self-concept in adolescents.

Combining MRI and Spectral EEG for Assessment of Neurocognitive Outcomes in Preterm Infants

Introduction: Predicting impairment in preterm children is challenging. Our aim is to explore the association between MRI at term-equivalent age (TEA) and neurocognitive outcomes in late childhood and to assess whether the addition of EEG improves prognostication. Methods: This prospective observational study included forty infants with gestational age 24 + 0–30 + 6. Children were monitored with multichannel EEG for 72 h after birth. Total absolute band power for the delta band on day 2 was calculated. Brain MRI was performed at TEA and scored according to the Kidokoro scoring system. At 10–12 years of age, we evaluated neurocognitive outcomes with Wechsler Intelligence Scale for Children 4th edition, Vineland adaptive behavior scales 2nd edition and Behavior Rating Inventory of Executive Function. We performed linear regression analysis to examine the association between outcomes and MRI and EEG, respectively, and multiple regression analysis to explore the combination of MRI and EEG. Results: Forty infants were included. There was a significant association between global brain abnormality score and composite outcomes of WISC and Vineland test, but not the BRIEF test. The adjusted R² was 0.16 and 0.08, respectively. For EEG, adjusted R² was 0.34 and 0.15, respectively. When combining MRI and EEG data, adjusted R² changed to 0.36 for WISC and 0.16 for the Vineland test. Conclusion: There was a small association between TEA MRI and neurocognitive outcomes in late childhood. Adding EEG to the model improved the explained variance. Combining EEG and MRI data did not have any additional benefit over EEG alone.

INTRODUCING PRAGMATICS IN USE (2ND EDITION)

Among the array of textbooks on linguistics in general and of pragmatics in particular, Introducing Pragmatics in Use (2nd edition) has emerged as a user-friendly guide to the field of pragmatics as it has been described as “a lively and accessible introduction to pragmatics” (O’Keeffe, Clancy &amp; Adolphs, 2020). As its name suggests, the book is designed with the combination of theoretical and practical aspects of pragmatics by not only introducing theories but also guiding the employment of the theories to examine real or naturally-occurring data in spoken and written forms. Introducing Pragmatics in Use (2nd edition) makes systematic use of several language corpora and related software programs. The adoption of the corpus technique to investigate key component areas, namely reference, speech acts, linguistic politeness, language variety, and register is its central focus. By analyzing various language settings offered by spoken and written corpora, the book aims at contextualizing pragmatics in linguistic study as well as making suggestions concerning applying pragmatics to teaching languages. It seeks to provide an introduction to the key theoretical and methodological issues in the study of Pragmatics; therefore, it is a good choice for senior undergraduate or graduate students enrolled in the courses of TESOL, applied linguistics, discourse analysis, corpus linguistics, or research methods in applied linguistics so that they can enhance their understanding of corpus pragmatics and apply its methodology to serve their researching and teaching purposes.

A NEXUS BETWEEN RELIGION, PHILOSOPHY AND SCIENCE With special reference to “The Reconstruction of Religious Thought in Islam”

Dr. Allama Muhammad Iqbal (1877-1938) (Iqbal, D. J. 1979) is a well-known Muslim theologian, philosopher, mystic, political theorist, politician, and wisdom poet of the 20th century. He is also known as the architect of Pakistan. He contributed in both the mediums of prose and poetry. His poetry is in both the languages Urdu and Persian. Similarly, he wrote and delivered lectures in both Urdu and English. His major philosophical work is in English. The magnum opus of his philosophical work is ‘The Reconstruction of Religious Thought in Islam’. This book consists of seven lectures. In the beginning, in 1924, he wrote an article on the concept of Ijtihad. He delivered it as a lecture on 13th December 1924 in Habibia Hall, Islamia College Lahore. Sheikh Abdul Qadir presided over the address. This lecture was warmly welcomed by Muslim intellectuals all over the subcontinent. The representative of the Madras Muslim Association Saith Jamal Ahmad invited Iqbal to deliver a series of lectures under the above-said title. He wrote and delivered six lectures in Madras in January 1929 and later at Hyderabad and Aligarh University. The 1st edition of this book was published in 1930 with six lectures. In 1932/1933 he visited England to participate in the second round table conference. During his stay in England at the request of Aristotelian Society London, he delivered a lecture under the title ‘Is Religion Possible?’ Later on, he included the above-mentioned lecture in the second edition of this book. The 2nd edition was published in 1934 by Oxford University Press. The problem of the relationship between religion, philosophy, and science was a subject of special interest to him. Although he discussed this issue in his wisdom poetry also but he systematically addressed it in this book which is his major philosophical contribution. This article is an effort to critically appreciate Allama Iqbal’s views on religion, philosophy, and science from the perspective of his philosophical discourse. Key Words: Religion, Philosophy, Science, Civilization, Reconstruction, Revelation, Reason

Foundations of Educational Technology: Integrative Approaches and Interdisciplinary Perspectives

This paper reviews the book “Book Review: Foundations of Educational Technology. Integrative Approaches and Interdisciplinary Perspectives”, written by J. Michael Spector (published in 2016 by Routledge, 2nd edition, first edition in 2012, 253 p.).

635. Is Azole Prophylaxis in Liver Transplant Recipients Effective in Preventing Invasive Candidiasis in the Era of Emerging Resistance?

Abstract Background Antifungal prophylaxis (px) in liver transplant (LT) recipients reduces invasive candidiasis (IC) and its associated mortality. Studies from our institution (UPMC) and others have shown that targeted px was as effective as universal px. Antifungal resistance has emerged among Candida spp., with ∼7% of the bloodstream isolates tested at CDC resistant to fluconazole. We sought to determine if our targeted antifungal px in LT recipients remained effective in the era of rising azole resistance. Methods We performed a retrospective study of patients undergoing LT at UPMC between 11/2010 and 06/2021. IC episodes were included if they occurred within 6 months of transplant. IC was defined using EORTC/MSGERC criteria, 2020. CLSI’s M60 2nd edition was used for antifungal susceptibility interpretation. Px was with fluconazole or voriconazole, based on risk factors for yeast or mold infection, respectively (Fig. 1). Results 1065 patients (pts) underwent LT over the study period. The most common indications for LT were HCC and NASH cirrhosis. Thirty-four pts (3%) developed IC within six months. 74% and 65% of these pts had risk factors for yeast or mold infection at some point, respectively (Table 1). Twenty-five of 34 (73.5%) pts received antifungal px, with voriconazole most commonly. Sixteen pts with IC (47%) had living donor transplant, and 11 (32%) had Roux-en-Y anastomosis. Types of IC were intra-abdominal candidiasis in 19 (56%), fungemia in 11 (32%), and intra-abdominal IC with secondary fungemia in 4 (12%). Seventeen (50%) episodes were breakthrough (BT) IC (most BT occurred in the voriconazole group), eight (24%) developed after stopping px, and nine (26%) occurred in those without px (Table 2). C. albicans and C. glabrata were the most common species (Fig. 2). Sixteen isolates underwent susceptibility testing: 12% and 44% were resistant and S-DD to fluconazole (Fig. 2); none were resistant to voriconazole. Attributable mortality of IC was 8%. Conclusion Targeted antifungal px in LT recipients with fluconazole or voriconazole effectively prevented IC, even in the era of rising azole resistance among Candida spp. We recommend antifungal susceptibility testing for Candida spp. obtained from infected sites to guide antifungal therapy. Disclosures Fernanda P. Silveira, MD, Ansun: Grant/Research Support|Janssen: Honoraria|Merck: Grant/Research Support|Novartis: Grant/Research Support|Regeneron: Grant/Research Support|Takeda: Advisor/Consultant|Takeda: Grant/Research Support.

Pendampingan Literasi Melalui Pembuatan Majalah “Jiwa” di MTs Sunan Drajat Banjarwati Paciran Lamongan

Community service is one from of the Tri Dharma of Higher Education in addition to education and research. In tertiary institutions, it can be said that KKN is a strategic method used to carry out the dharma of their service. In addition, KKN, which is an integral part of the curriculum, is also a medium for experiential learning or experience based learning. This jurnal aims to describe the report on the results of KKN using the ABCD method. In the ABCD principle, the ability of the community to identify the assets, strenghts and potential they have is seen as capable of moving and motivating them to make changes as well as being the main actors of the change. Through this service, the author is able to utilize and develop the assets owned by the MTs Sunan Drajat Banjarwati institution through literacy assistance with the output of making the 2nd edition of the JIWA magazine which has been in hiatus for approximately 7 years. So the output printed in the ABCD KKN is the launching of the magazine on september 7, 2021 at the same time as the closing of the KKN

Prenatal and Childhood Smoke Exposure Associations with Cognition, Language, and Attention-Deficit/Hyperactivity Disorder

To assess the relationships of prenatal and childhood smoke exposure with specific neurodevelopmental and behavioral problems during early childhood. A subsample (n=386) of mother-child dyads from the Newborn Epigenetic Study (NEST) prebirth cohort participated in the study. Cotinine concentrations were used to objectively measure prenatal and childhood smoke exposure when youth were aged 3-13years. Multivariable regression models were used to estimate associations of prenatal and childhood cotinine concentrations with performance on the National Institutes of Health (NIH) Toolbox and attention-deficit/hyperactivity disorder and behavioral symptoms, measured using the Behavior Assessment System for Children, 2nd edition (BASC-2). After adjusting for confounders, childhood cotinine concentrations were associated with poorer cognitive performance on tasks measuring cognitive flexibility (B=-1.29; P=.03), episodic memory (B=-0.97; P=.02), receptive language development (B=-0.58; P=.01), and inhibitory control and attention (B=-1.59; P=.006). Although childhood cotinine concentration was associated with higher levels of attention problems (B=0.83; P=.004) on the BASC-2, after adjustment for confounders, the association is nonsignificant. Although associations for maternal cotinine concentrations were null, an interaction was detected between prenatal and childhood cotinine concentrations on the NIH Toolbox Picture Vocabulary Task (P=.02). Our findings suggest that childhood tobacco smoke exposure may lead to poorer attention regulation and language acquisition, complex visual processing ability, and attention problems.

Extremely preterm children and relationships of minor neurodevelopmental impairments at 6 years.

This study investigated minor impairments in neurological, sensorimotor, and neuropsychological functioning in extremely preterm-born (EPT) children compared to term-born children. The aim was to explore the most affected domains and to visualize their co-occurrences in relationship maps. A prospective cohort of 56 EPT children (35 boys) and 37 term-born controls (19 boys) were assessed at a median age of 6 years 7 months with Touwen Neurological Examination, Movement Assessment Battery for Children, 2nd edition (MABC-2), Sensory Integration and Praxis Test (SIPT), and a Developmental Neuropsychological Assessment, 2nd edition (NEPSY-II). Altogether 20 test domains were used to illustrate the frequency of impaired test performances with a bar chart profile and to construct relationship maps of co-occurring impairments. The EPT children were more likely to perform inferiorly compared to the term-born controls across all assessments, with a wider variance and more co-occurring impairments. When aggregating all impaired test domains, 45% of the EPT children had more impaired domains than any term-born child (more than five domains, p < 0.001). Relationship maps showed that minor neurological dysfunction (MND), NEPSY-II design copying, and SIPT finger identification constituted the most prominent relationship of co-occurring impairments in both groups. However, it was ten times more likely in the EPT group. Another relationship of co-occurring MND, impairment in NEPSY-II design copying, and NEPSY-II imitation of hand positions was present in the EPT group only. Multiple minor impairments accumulate among EPT children at six years, suggesting that EPT children and their families may need support and timely multi-professional interventions throughout infancy and childhood.

Report on the 2nd Linked Archives International Workshop (LinkedArchives 2022) at TPDL 2022

The 2nd edition of the International Workshop on Archives and Linked Data ran in conjunction with the 26th International Conference on Theory and Practice of Digital Libraries (TPDL 2022). TPDL 2022 was an in-person event in Padua with an online-only registration for non-speakers. Archives, the guardians of large volumes of historical and current information, are showing a growing interest in linked data and semantic web technologies. These technologies can be used to link archives' information with data from other cultural heritage institutions and more informal sources. In a world of linked data, users can access richer interfaces where the archival records are available in their context, with explicit metadata. The workshop gathered about 20 researchers and specialists engaged in initiatives crossing linked data technologies, archives, and cultural heritage in general, discussing advances and challenges in this area. The workshop was a successful event, with active participation in the discussions that followed the presentations. The participants found the workshop interesting (40%) or extremely interesting (60%), and everyone who answered a post-workshop survey would be interested in another edition of the workshop. Date: 20 September, 2022. Website: https://linkedarchives.inesctec.pt/.

PCR279 Value-Based Assessment of Clinical Trial Outcomes: A Hypothetical Example Using the Childhood Autism Rating Scale in Autism Spectrum Disorder

This research explores the application of patient preferences, as estimated by a discrete choice experiment (DCE), to hypothetical clinical trial results in childhood autism spectrum disorder (ASD), as measured by (between-group) changes from baseline. In childhood ASD, the Childhood Autism Rating Scale–2nd edition (CARS2) instrument is used to assess severity and change.

Hubungan Intensitas Nyeri Kepala Tipe Tegang Dengan Derajat Depresi

Depression is a natural feeling disorder (mood) which is characterized by excessive feelings of sadness, depression, lack of enthusiasm, feeling worthless, feeling that life is empty and hopeless, thinking is centered on failure and self-blame or self-blame, and often accompanied by envy and suicidal thoughts. Depressive disorders can occur in anyone with a higher risk of physical illness, which is about 15-60%. Medical conditions that have long been associated with depressive disorders include primary tension-type headache (TTH). Patients with chronic TTH will experience more severe depression than episodic TTH and chronic headache is significantly associated with psychopathological scores, but the direction of the relationship is not clear. This study aims to determine the relationship between the intensity of tension-type headaches and the degree of depression. This research is an observational analytic study with a cross sectional research design. To find out the frequency and duration of tension-type headaches, the history and filling of the questionnaire provided were carried out. Then the Beck Depression Inventory (BDI) questionnaire was used to assess the degree of depression. Patients with tension headaches were assessed based on The International Headache Classification 2nd Edition in 2004, and pain intensity was assessed based on the NPRS (Numeric Pain Rating Scale) score. The results showed that the Spearman correlation test obtained a significance value of 0.014, a correlation value of 0.399. between the Numeric Pain Rating Scale (NPRS) and Visual Analog Scale (VAS) scores with the Beck Depression Inventory (BDI) score on the subject of tension-type headache, and there is a significant relationship between the intensity of the tension-type headache and depression where the higher the pain intensity, the more severe the pain. degree of depression.