Groundwater Rn concentration has been monitored at several sites in the Campi Flegrei Caldera since the time of the last episode of bradyseismic activity. The results concerning the period 1983–88 indicate that the Rn concentration is spatially variable due to the different chemico-physical characteristics of the waters or structural features. Rn concentration is generally influenced by the long-term changes of meteorological factors. Rainfalls appear to affect the Rn content of the most superficial aquifers. Several short-term spike-like Rn anomalies have been detected both during and after the period of the bradyseismic crisis. They do not show correlation with temporal changes of the pH and/or temperature of waters. A systematic correlation between Rn anomalies and episodic strong rainfall events is also absent. Furthermore, a clear relationship between Rn spikes and both uplift velocity changes and seismic activity has not been found. The overall evidence makes it very difficult to understand the temporal changes of groundwater Rn concentration that have occurred during and after the 1982–84 bradyseismic crisis. Nevertheless, a clear causal relationship between Rn concentration and the dynamics of the bradyseism is observed in some monitored sites. Its appearance may have been favoured by the low Rn concentration in the groundwaters during periods of quiescent activity.